-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

626.O1.6 626. Aggressive Lymphoma (Diffuse Large B-Cell and Other Aggressive B-Cell Non-Hodgkin Lymphomas)—Results from Prospective Clinical Trials: Updates and advances in bispecific antibody therapies and autologous CAR-T approaches Clinically Relevant Abstract

Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Adult, antibodies, Biological, CRS, Diseases, Lymphoma (any), CAR-Ts, Therapies, Non-Hodgkin Lymphoma, Adverse Events, B-Cell Lymphoma, Biological Processes, DLBCL, immunotherapy, Lymphoid Malignancies, Study Population, Clinically relevant, immune mechanism
Sunday, December 6, 2020: 12:00 PM-1:30 PM
Moderators:
Eliza A Hawkes, FRACP, MD, MBBS, Austin Health, University of Melbourne and Paul M. Barr, MD, Medical Director, Clinical Trial Office, Professor of Medicine, James P. Wilmot Cancer Institute, University of Rochester Medical Center
Disclosures:
Barr: Seattle Genetics: Consultancy; TG therapeutics: Consultancy, Research Funding; Morphosys: Consultancy; Gilead: Consultancy; AstraZeneca: Consultancy, Research Funding; Verastem: Consultancy; Celgene: Consultancy; Merck: Consultancy; Genentech: Consultancy; Janssen: Consultancy; Abbvie/Pharmacyclics: Consultancy, Research Funding.
12:00 PM

Rajat Bannerji, MD, PhD1, John N. Allan, MD2, Jon E. Arnason, MD3, Jennifer R. Brown, MD, PhD4*, Ranjana Advani, MD5, Stephen M. Ansell, MD, PhD6, Susan M. O'Brien, MD7, Johannes Duell, MD8*, Peter Martin, FRCPC, MD, MS2, Robin M. Joyce, MD9, Jingjin Li, PhD10*, Dina M. Flink, PhD10*, Min Zhu, PhD10*, David M. Weinreich, MD10*, George D. Yancopoulos, MD, PhD10*, Andres Sirulnik, MD, PhD10, Aafia Chaudhry, MD, MBA, MS10*, Srikanth R. Ambati, MBBS, MD10* and Max S. Topp, MD8

1Rutgers Cancer Institute of New Jersey, New Brunswick, NJ
2Weill Cornell Medicine, New York, NY
3Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
4Dana-Farber Cancer Institute, Boston, MA
5Stanford University, Stanford, CA
6Division of Hematology, Mayo Clinic, Rochester, MN
7Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange, CA
8Universitätsklinikum Würzburg, Würzburg, Germany
9Beth Israel Deaconess Medical Center, Boston, MA
10Regeneron Pharmaceuticals, Inc., Tarrytown, NY

12:15 PM

Adam J Olszewski, MD1, Abraham Avigdor, MD2,3, Sunil Babu4*, Itai Levi, MD5*, Uri Abadi2,6*, Houston Holmes7*, Matthew McKinney8, Ron McCord9*, Yuying Xie10*, Cindy Chen9*, Kati Sarouei9*, Naseer Qayum11*, Carol O’Hear9*, Gila Sellam12* and Herbert Eradat13

1Brown University, Providence, RI
2Tel Aviv University, Tel Aviv, Israel
3Institute of Hematology, Sheba Medical Center, Ramat Gan, Israel
4Fort Wayne Medical Oncology and Hematology, Fort Wayne, IN
5Soroka University Medical Center, Be'er-Sheva, Israel
6Meir Medical Center, Kfar Saba, Israel
7Texas Oncology, Dallas, TX
8Duke Cancer Institute, Durham, NC
9Genentech, Inc., South San Francisco, CA
10F. Hoffmann-La Roche Ltd, Mississauga, Canada
11F. Hoffmann-La Roche Ltd, Welwyn Garden City, United Kingdom
12F. Hoffmann-La Roche Ltd, Basel, Switzerland
13University of California, Los Angeles, CA

12:30 PM

Martin Hutchings, MD, PhD1*, Rogier Mous, MD, PhD2*, Michael Roost Clausen, MD, PhD3*, Peter Johnson, MD, FRCP4, Kim M Linton5*, Martine E.D. Chamuleau, MD, PhD6, David John Lewis, MD7*, Anna Sureda Balari, MD, PhD8*, David Cunningham, MD, FRCP, FMedSci9*, Roberto S Oliveri, MD, PhD10*, Dena DeMarco11*, Brian Elliott, MD11, Kuo-mei Chen, PhD11* and Pieternella J. Lugtenburg, MD, PhD12

1Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
2on behalf of the Lunenburg Lymphoma Phase I/II Consortium-HOVON/LLPC, Universitair Medisch Centrum Utrecht, Utrecht, Netherlands
3Vejle Hospital, Vejle, Denmark
4Cancer Research UK, Cancer Services, University of Southampton, Southampton, United Kingdom
5Christie Hospital NHS Foundation Trust, Manchester, United Kingdom
6on behalf of the Lunenburg Lymphoma Phase I/II Consortium-HOVON/LLPC, VU University Medical Center, Amsterdam, Netherlands
7Plymouth University Medical School, Plymouth, United Kingdom
8Institut Català d'Oncologia-Hospital Duran i Reynals, Hospitalet del Llobregat, Spain
9The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom
10Genmab A/S, Copenhagen, Denmark
11Genmab, Princeton, NJ
12Erasmus MC Cancer Institute, department of Hematology, Rotterdam, Netherlands

12:45 PM

Martin Hutchings, MD, PhD1*, Carmelo Carlo-Stella, MD2, Emmanuel Bachy, MD, PhD3*, Fritz Offner, MD, PhD4, Franck Morschhauser, MD, PhD5*, Michael Crump6, Gloria Iacoboni, MD7*, Anna Sureda Balari, MD, PhD8*, Joaquin Martinez-Lopez, MD9*, Linda Lundberg10*, Mark Dixon11*, David Perez Callejo10*, James Relf11*, David Carlile11*, Emily Piccione12*, Kathryn Humphrey11* and Michael Dickinson, MBBS, FRACP, FRCPA13

1Rigshospitalet, Copenhagen, Denmark
2Humanitas Clinical and Research Center, and Humanitas University, Milan, Italy
3Hospices Civils De Lyon and Université Claude Bernard, Pierre-Bénite, France
4Universitair Ziekenhuis Gent, Ghent, Belgium
5Hôpital Claude Huriez and Centre Hospitalier Régional Universitaire de Lille, Lille, France
6Princess Margaret Hospital, Toronto, ON, Canada
7Vall d’Hebron University Hospital, Barcelona, Spain
8Institut Català d'Oncologia-Hospital Duran i Reynals, Hospitalet del Llobregat, Spain
9Hospital Universitario 12 de Octubre (H12O), Centro Nacional de Investigaciones Oncológicas (CNIO)-H12O and Universidad Complutense de Madrid, Madrid, Spain
10F. Hoffmann-La Roche Ltd, Basel, Switzerland
11Roche Products Ltd, Welwyn Garden City, United Kingdom
12Genentech, Inc., South San Francisco, CA
13Peter MacCallum Cancer Centre, Royal Melbourne Hospital and The University of Melbourne, Melbourne, VIC, Australia

1:00 PM

Peter Borchmann1, Anja Jühling1*, Philipp Gödel1*, Hyatt Balke-Want1*, Christoph Schmid2*, Francis A. Ayuk3*, Silke Holtkamp4*, Liane Preussner4*, Gregor Zadoyan4*, Linda Hanssens4*, Andrew Kaiser5*, Marion Jurk5*, Iris Bürger5*, Dina Schneider6*, Boro Dropulic6*, Toon Overstijns4,5*, Christof Scheid, MD7, Udo Holtick8*, Stefan Miltenyi4,5,6* and Michael Hallek1,8

1Department of Internal Medicine I, Cologne Lymphoma Working Group, University Hospital of Cologne, Cologne, Germany
2II. Med. Klinik Hämatologie/Onkologie, Universitäts-Klinikum Augsburg, Augsburg, Germany
3UKE Hamburg-Eppendorf, Hamburg, Germany
4Miltenyi Biomedicine GmbH, Bergisch Gladbach, Germany
5Miltenyi Biotec B.V. & Co. KG, Bergisch Gladbach, Germany
6Lentigen Technology Inc., A Miltenyi Company, Gaithersburg, MD
7Department of Internal Medicine I, Leukapheresis and Stem Cell Transplant Unit, University of Cologne, Cologne, Germany
8Department of Internal Medicine I, Leukapheresis and Stem Cell Transplant Unit, University Hospital of Cologne, Cologne, Germany

1:15 PM

Sattva S. Neelapu, MD1, Michael Dickinson, MBBS, FRACP, FRCPA2, Matthew L. Ulrickson, MD3, Olalekan O. Oluwole, MBBS, MPH4, Alex F. Herrera, MD5, Catherine Thieblemont, MD, PhD6, Chaitra S. Ujjani, MD7, Yi Lin, MD, PhD8, Peter A. Riedell, MD9*, Natasha Kekre, MD, MPH, FRCPC10, Sven de Vos, MD, PhD11, Yin Yang, MS12*, Francesca Milletti, PhD12*, Lovely Goyal, PhD12*, Jun Kawashima, MD12* and Julio C. Chavez, MD13

1The University of Texas MD Anderson Cancer Center, Houston, TX
2Peter MacCallum Cancer Centre and University of Melbourne, East Melbourne, VIC, Australia
3Banner MD Anderson Cancer Center, Gilbert, AZ
4Vanderbilt-Ingram Cancer Center, Nashville, TN
5City of Hope National Medical Center, Duarte, CA
6Hospital Saint-Louis, Paris, France
7Seattle Cancer Care Alliance/Fred Hutchinson Cancer Research Center, Seattle, WA
8Mayo Clinic, Rochester, MN
9University of Chicago Medicine, Chicago, IL
10The Ottawa Hospital, Ottawa, ON, Canada
11David Geffen School of Medicine at UCLA, Santa Monica, CA
12Kite, a Gilead Company, Santa Monica, CA
13Moffitt Cancer Center, Tampa, FL

*signifies non-member of ASH