-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

618.O2.6 618. Acute Lymphoblastic Leukemia: Biology, Cytogenetics, and Molecular Markers in Diagnosis and Prognosis II Clinically Relevant Abstract

Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Adult, ALL, Biological, Leukemia, Diseases, cell regulation, Therapies, Biological Processes, immune cells, Technology and Procedures, Young Adult, epigenetics, Lymphoid Malignancies, Study Population, Clinically relevant, genetic profiling, genomics, NK cells, immune mechanism, molecular testing, NGS, RNA sequencing, pathways, signal transduction
Sunday, December 6, 2020: 12:00 PM-1:30 PM
Moderators:
Emmanuelle Clappier, PharmD, PhD, and Jean-Pierre Bourquin, MD, PhD, Division of Pediatric Oncology, and Children Research Center, University Children´s Hospital
Disclosures:
No relevant conflicts of interest to declare.
12:00 PM

Shawn Lee, MBBS1, Maoxiang Qian, PhD2, Wentao Yang, PhD1, Jonathan Diedrich, PhD1*, Elizabeth A. Raetz, MD3, Wenjian Yang, PhD1*, Qian Dong, PhD1*, Meenakshi Devidas, PhD4*, Deqing Pei, MS5*, Allen Eng Juh Yeoh, MD6*, Cheng Cheng, PhD5*, Ching-Hon Pui, MD7, William E. Evans, PharmD1, Charles G Mullighan, MBBS, MD8, Stephen P Hunger, MD9, Daniel Savic, PhD1, Mary V. Relling, PharmD1, Mignon L. Loh, MD10 and Jun J. Yang, PhD1

1Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN
2Children's Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, TN
3New York University Langone Medical Center, New York, NY
4Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN
5Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN
6Centre for Translational Research in Acute Leukaemia, Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
7Department of Oncology, Member, St Jude Faculty, Chair, Oncology Department, Coleader, Hematological Malignancies Program, Director, China Region, St Jude Global, American Cancer Society Professor, Fahad Nassar Al-Rashid Chair of Leukemia Research, St Jude Children’s Research H, Memphis, TN
8Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN
9Department of Pediatrics, Division of Oncology and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
10Department of Pediatrics, Division of Pediatric Hematology/Oncology, University of California Benioff Children’s Hospital, San Francisco, CA

12:15 PM

Martin Neumann1*, Lorenz Bastian2*, Sonja Hänzelmann1*, Alina Hartmann1*, Heiko Trautmann, PhD1*, Jutta Ortiz Tanchez3*, Cornelia Schlee3*, Michael P Schroeder, PhD3*, Lars R. Fransecky, MD2*, Sebastian Vosberg4*, Walter Fiedler, MD5, Nael Alakel, MD6*, Mustafa Kondakci, MD7*, Michael Starck, MD8*, Stefan Schwartz, MD, PhD3*, Carsten Müller-Tidow, MD9*, Folker Schneller10*, Albert Reichle11*, Thomas Burmeister3*, Philipp A. Greif, MD, PD4, Monika Brüggemann, MD1*, Nicola Goekbuget, MD12 and Claudia D Baldus, MD1*

1Medical Department II, Hematology and Oncology, University Hospital Schleswig-Holstein, Kiel, Germany
2Hematology and Oncology, University Hospital Schleswig-Holstein, Kiel, Germany
3Department of Hematology / Oncology, Charité - Universitätsmedizin Berlin, Berlin, Germany
4Department of Internal Medicine III, Ludwig-Maximilians-University, Munich, Germany
5Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
6University Hospital, Dresden, Germany
7Dept. of Hematology, Oncology and Clinical Immunology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany
8Medical Department I, Hospital München-Schwabing, München, Germany
9Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany
10Medical Department III, Klinikum rechts der Isar, Technical University Munich, Munich, Germany
11Department of Hematology and Oncology, University Hospital Regensburg, Regensburg, Germany
12University Hospital, Department of Medicine II, Hematology/Oncology, Head of Study Center Depart of Medicine II, Hematology/Oncology Goethe University Hospital, Frankfurt, Germany

12:30 PM

Daniela Kužílková, PhD1*, Tomas Kalina, MD, PhD1*, Cristina Bugarin, Dr.2*, Katerina Rejlová, Dr.1*, Daniel Thurner, Dr.1*, Pavel Semerák, Dr.1*, Jan Stuchly, MSc1*, Andrea Biondi, MD, PhD2 and Giuseppe Gaipa, PhD3

1CLIP - Childhood Leukaemia Investigation Prague, Department of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic
2Tettamanti Research Center, Department of Pediatrics, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy
3Tettamanti Research Center, Department of Pediatrics, University of Milano - Bicocca/Fondazione MBBM, Monza, Italy

12:45 PM

Caroline Duault, PharmD, PhD1*, Anil Kumar, PhD2*, Adeleh Taghi Khani, PhD2*, Sung June Lee, BA2*, Lu Yang, PhD3*, Min Huang, PhD4*, Christian Hurtz, PhD5, Bryan Manning, BS6*, Lucy Ghoda, PhD7*, Tinisha McDonald, BS8*, Norman J. Lacayo, MD4, Kathleen M. Sakamoto, MD, PhD4, Martin P. Carroll, MD9, Guido Marcucci, MD10, Jianhua Yu, PhD11*, Michael A. Caligiuri, MD12, Holden T. Maecker, PhD13* and Srividya Swaminathan, PhD2,14

1Institute for Immunity, Transplantation and Infections, Stanford University - School of Medicine, Stanford, CA
2Department of Systems Biology, Beckman Research Institute of City of Hope, City of Hope, Duarte, CA
3Department of Systems Biology, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA
4Department of Pediatrics, Stanford University School of Medicine, Stanford, CA
5Medicine, University Of Pennsylvania, Philadelphia, PA
6University of Pennsylvania, Philadelphia, PA
7Department of Hematologic Malignancies Translational Science, Gehr Family Center for Leukemia Research, Beckman Research Institute, City of Hope, Duarte, CA
8Hematogic Malignancies Translational Science, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA
9Medicine, University of Pennsylvania, Philadelphia, PA
10Department of Hematologic Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematologic Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope, Monrovia, CA
11Department of Hematology and Hematopoietic Stem Cell Transplantation, Beckman Research Institute of City of Hope, City of Hope, Duarte, CA
12City of Hope National Medical Center, Duarte, CA
13Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA
14Department of Hematological Malignancies and Translational Science, Beckman Research Institute of City of Hope, City of Hope, Duarte, CA

1:00 PM

Yuya Sasaki, MD, PhD1, Hagop M. Kantarjian, MD2, Nicholas J. Short, MD1, Nitin Jain, MD3, Koji Sasaki, MD4, Farhad Ravandi, MBBS5, Marina Konopleva, MD, PhD6, Guillermo Garcia-Manero, MD1, Latasha Little, BS7*, Curtis Gumbs8*, Li Zhao, PhD9*, P Andrew Futreal, PhD10*, Feng Wang, PhD11*, Ken Furudate, DDM, PhD1*, Rebecca Garris, MSc1*, Koichi Takahashi, MD, PhD11 and Elias Jabbour, MD1

1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
2University of Texas MD Anderson Cancer Center, Houston, TX
3Associate Professor of Medicine Department of Leukemia The University of Texas MD Anderson Cancer Center, Houston, TX
4Department of Leukemia, MD Anderson Cancer Center, Houston, TX
5Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX
6Department of Leukemia, University of Texas, MD Anderson Cancer Center, Houston, TX
7Department of Genomics Medicine, UT M. D. Anderson Cancer Center, Houston, TX
8The University of Texas MD Anderson Cancer Center, Houston, TX
9UT MD Anderson Cancer Center, Houston, TX
10Department of Genomic Medicine, UT M. D. Anderson Cancer Center, Houston, TX
11Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

1:15 PM

Janine Stutterheim, MD, PhD1, Inge M. van der Sluis, MD, PhD2, Paola De Lorenzo3*, Julia Alten, MD4*, Philip Ancliff, MD5*, Andishe Attarbaschi, MD6,7*, Benoit Brethon, MD8*, Andrea Biondi, MD9,10, Myriam Campbell, MD11*, Giovanni Cazzaniga, PhD12, Gabriele Escherich, MD13,14*, Alina Ferster, MD15, Rishi Sury Kotecha, MBBChir, PhD16,17*, Birgitte Lausen, MD18,19*, Chi Kong Li, MD20, Luca Lo Nigro, PhD, MD21, Franco Locatelli, MD, PhD22, Rolf Marschalek, PhD23*, Martin Schrappe, MD PhD24, Jan Stary, MD, PhD25*, Ajay Vora, MD26,27, Jan Zuna, PhD28, Vincent H.J. Van Der Velden, PhD29*, Tomasz Szczepanski, MD, PhD30,31, Maria Grazia Valsecchi, PhD32* and Rob Pieters, MD, PhD, MSc33

1Princess Maxima Center, Utrecht, Netherlands
2Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands
3University of Milano-Bicocca, Monza, Italy
4Dept. of Pediatrics, UKSH, Kiel, DEU
5Department of Haematology, Great Ormond Street Hospital, London, UK, London, GBR
6St. Anna Children's Hospital, Vienna, Austria
7BFM-A – Berlin-Frankfurt-Münster Austria, Vienna, Austria
8FRALLE - French Acute Lymphoblastic Leukemia Study Group, Paris, France
9Dept. Pediatrics, University of Milano-Bicocca, Fondazione MBBM/San Gerardo Hospital, Monza, Italy
10AIEOP - Associazione Italiana Ematologia Oncologia Pediatrica, Monza, Italy
11Hospital Roberto del Rio Santiago, Chilean National Pediatric Oncology Group, PINDA., Santiago, Chile
12Tettamanti Research Center, Department of Pediatrics, University of Milano-Bicocca/Fondazione MBBM, Monza, Italy
13Department of Pediatric Hematology and Oncology, University Medical Center Hamburg, Hamburg, Germany
14COALL - German Cooperative Study Group for Childhood Acute Lymphoblastic Leukemia, Hamburg, Germany
15Hematology Oncology, Hôpital Universitaire des Enfants Reine Fabiola, Université Libre de Bruxelles, Brussels, Belgium
16Telethon Kids Institute, University of Western Australia, Perth, Australia
17ANZCHOG - Australia New Zealand Children Oncology Group, Perth, Australia
18NOPHO – Nordic Society of Pediatric Hematology/Oncology, Copenhagen, Denmark
19Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
20Department of Paediatrics, The Chinese University of Hong Kong, Shatin, Hong Kong
21Head of Cytogenetic-Cytofluorimetric-Molecular Biology Lab - Azienda Policlinico OVE - Center of Pediatric Hematology Oncology, Catania, Italy
22IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Sapienza, University of Rome, Rome, Italy
23DCAL, Institute of Pharmaceutical Biology, Goethe-University, Frankfurt am Main, Germany
24BFM-G - Berlin-Frankfurt-Münster Group Germany, Kiel, Germany
25CPH- Czech Working Group for Pediatric Hematology, Prague, Czech Republic
26Great Ormond Hospital, London, United Kingdom
27UKCCSG - United Kingdom Children Cancer Study Group, London, United Kingdom
28CLIP, Dept. of Paediatric Haematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic
29Department of Immunology, Erasmus University Medical Center, Rotterdam, NLD
30Department of Pediatrics Hematology and Oncology in Zabrze, Medical University of Silesia, Zabrze, Poland
31PPLLSG - Polish Pediatric Leukemia/Lymphoma Study Group, Zabrze, Poland
32University of Milano Bicocca, Monza, Italy
33Princess Maxima Center for Pediatric Oncology, Utrecht, Netherlands

*signifies non-member of ASH