Kanak Joshi, MS^1*, Shanhui Liu, PhD^2*, Lei Zhang, PhD^3*, Ryan Michael Mack, BS⁴, Austin Runde, MS^5*, Patrick Hagen, MD, MPH^6*, Kevin Barton, MD⁷, Peter Breslin, PhD^8*, Ameet R. Kini, MD, PhD⁹ and Jiwang Zhang, MD, PhD^1*

¹Department of Cancer Biology, Loyola University Medical Center, Maywood, IL
²Second Hospital of Lanzhou University, Lanzhou, China
³Soochow University, Suzhou, China
⁴Department of Cancer Biology, Loyola University Chicago, Oak Park, IL
⁵Loyola University Medical Center, Maywood
⁶Division of Hematology and Oncology, Loyola University Medical Center, Maywood, IL
⁷Department of Medicine, Loyola University-Chicago, Maywood, IL
⁸Department of Cancer, Loyola University Medical Center, Maywood, IL
⁹Loyola Univ. Medical Ctr., Maywood, IL

Sheida Hayati^1*, Amer M. Zeidan, MBBS, MHS², Guillermo Garcia-Manero, MD³, Uwe Platzbecker, MD⁴, Aarif Ahsan^5*, Amit K. Verma, MD⁶, Srinivas Aluri, PhD^7*, Manuel Ugidos Guerrero^1*, Anita K. Gandhi, PhD⁸, Rajasekhar N.V.S. Suragani, PhD⁹ and Sadanand Vodala⁹

¹Informatics and Predictive Sciences, Bristol Myers Squibb, Princeton, NJ
²Department of Internal Medicine, Yale Cancer Center and Smilow Cancer Hospital, New Haven, CT
³Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Department of Hematology, Cell Hematology and Hemostaseology, Leipzig University Hospital, Leipzig, Germany
⁵Formerly Translational Medicine, Bristol Myers Squibb, Summit, NJ
⁶Department of Oncology, Albert Einstein College of Medicine, New York, NY
⁷Montefiore Einstein Cancer Center, Blood Cancer Institute, Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY
⁸Bristol Myers Squibb, Summit, NJ
⁹Hematology, Translational Medicine and Disease Team, Bristol Myers Squibb, Summit, NJ

Safa F Mohamad, PhD^1*, Meaghan McGuinness^2*, Gabriele Casirati, MD, PhD², Chad Everett Harris, MS^2*, Raffaele Renella, MD, PhD³, Pietro Genovese, PhD², Eric Allenspach, MD, PhD^4* and David A. Williams, MD²

¹Boston Children's Hospital/ Harvard Medical School, Boston, MA
²Boston Children's Hospital, Boston, MA
³Pediatric Hematology-Oncology Research Laboratory, University Hospital of Lausanne, Lausanne, VD, Switzerland
⁴Seattle Children's Hospital, Seattle, WA

Devendra Hiwase, MD, MBBS, PhD, FRACP, FRCPA^1,2,3, David M. Ross, MBBS, PhD, FRACP, FRCPA^1,2,4,5,6*, Steven W. Lane, MD, PhD⁷, Chloe Thompson-Peach, PhD^1,5*, Chun Yew Fong^8*, Agnes S. M. Yong, MD, PhD^1,9, David T Yeung, MBBS, PhD, BSc, FRACP, FRCPA^1,2, Timothy P Hughes, MD, MBBS, FRACP, FRCPA^2,10 and Daniel Thomas, MD, PhD^1,2,5

¹Blood Cancer, Precision Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia
²Haematology, Central Adelaide Local Health Network (CALHN), Adelaide, SA, Australia
³Adelaide Medical School, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia
⁴Department of Haematology, Flinders Medical Centre and University, Adelaide, SA, Australia
⁵Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia
⁶Department of Haematology, Centre for Cancer Biology, SA Pathology, Adelaide, SA, Australia
⁷Cancer Program, QIMR BERGHOFER MEDICAL RESEARCH, Herston, Brisbane, AUS
⁸Department of Hematology, Austin Health, Heidelberg, VIC, Australia
⁹Haematology Department, Royal Perth Hospital, Perth, Australia
¹⁰South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia

Fang Hu^1*, Xiaojin Li^2*, Robert Peter Gale, MD³, Suning Chen^4* and Yang Liang, MD, PhD⁵

¹Sun Yat-sen University Cancer center, Guangzhou, CHN
²The Affiliated Hospital of Yunnan university, Kunming, China
³University of California, Los Angeles, Los Angeles, CA
⁴National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, Collaborative Innovation Center of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China
⁵Sun Yat-sen University Cancer Center, Guangzhou, China

Valeria Velez Galiano, BS^1,2*, Gloria Garcia, PhD^1*, David M Swoboda, MD^3*, Katherine McKinnon, PhD^4*, Dan Larson, PhD^1,2,5* and Kathy L McGraw^1,2,5*

¹Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, National Institute of Health, Bethesda, MD
²Myeloid Malignancies Program, National Institute of Health, Bethesda, MD
³Tampa General Hospital Cancer Institute, Tampa, FL
⁴Vaccine Branch Flow Cytometry Core, National Cancer Institute, Center for Cancer Research, National Institute of Health, Bethesda, MD
⁵Immune Deficiency – Cellular Therapy Program, National Institute of Health, Bethesda, MD

Aintzane Diaz-Mazkiaran, MSc^1,2,3*, Guillermo Serrano, PhD^1,2,4*, Nerea Berastegui^1,3*, Paula Garcia-Olloqui^1,3*, Sofia Huerga^5*, Ana Alfonso Pierola, M.D., Ph.D.^5*, Asier Ullate-Agote^1*, Beñat Ariceta^1*, Marina Ainciburu, MSc^1,3*, Amaia Vilas-Zornoza^1,3*, Patxi San-Martin^1,3*, Paula Aguirre-Ruiz^1*, Jose Maria Lamo De Espinosa^6*, Pamela Acha^7*, Oriol Calvete^7*, Tamara Jimenez^8*, Antonieta Molero^9*, Julia Montoro^9*, Maria Diez-Campelo, MD, PhD^3,8*, David Valcarcel, MD, PhD⁹, Francesc Sole, PhD⁷, Idoia Ochoa^4,10*, Teresa Ezponda^1,3*, Felipe Prosper, MD, PhD^1,3,5 and Mikel Hernaez, PhD^2,3,10*

¹Hematology and Oncology Program, Centre for Applied Medical Research (CIMA), Instituto de Investigaciones Sanitarias de Navarra (IdiSNA), Cancer Center Clinica Universidad de Navarra (CCUN), Pamplona, Spain
²Computational Biology Program. Cima Universidad de Navarra. IdiSNA and Data Science and Artificial Intelligence Institute (DATAI), Universidad de Navarra, Pamplona, Spain
³Centro de Investigación Biomédica en Red de Cáncer, CIBERONC, Madrid, Spain
⁴Department of Electrical and Electronics engineering, School of Engineering (Tecnun), University of Navarra, Donostia, Spain
⁵Hematology and Cell Therapy Department, Clínica Universidad de Navarra, Instituto de Investigaciones Sanitarias de Navarra (IdiSNA), Cancer Center Clinica Universidad de Navarra (CCUN) and Centro de Investigación Biomédica en Red de Cancer (CIBERONC), Pamplona, Spain
⁶Department of Orthopedics, Clínica Universidad de Navarra, Pamplona, Spain
⁷MDS Group, Josep Carreras Leukaemia Research Institut, ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, Barcelona, Spain
⁸Department of Hematology, Hospital Universitario de Salamanca-IBSAL, Salamanca, Spain
⁹Service of Hematology, Hospital Universitari Vall d’Hebron, Barcelona; Vall d’Hebron Instituto de Oncología (VHIO), Barcelona, Spain
¹⁰Instituto de Ciencia de los Datos e Inteligencia Artificial (DATAI), Universidad de Navarra, Pamplona, Spain

Maki Sakuma, MD^1,2*, Constance Regina Baer, PhD¹, Manja Meggendorfer, PhD¹, Claudia Haferlach, MD¹, Wolfgang Kern, MD¹, Torsten Haferlach, MD, PhD¹ and Wencke Walter, PhD^1*

¹MLL Munich Leukemia Laboratory, Munich, Germany
²Technical University Munich, Medical Graduate Center, Munich, Germany

Monika Kutyna, PhD^1,2*, Maha M Kamel, MBioChem, BScPharm^2,3*, David M. Ross, MBBS, PhD, FRACP, FRCPA^1,2,3,4,5*, Agnes S. M. Yong, MD, PhD^2,6, Chun Yew Fong, MBBS, FRACP, FRCPA, PhD⁷, Chloe Thompson-Peach, PhD^2,3*, Steven W. Lane, MD, PhD⁸, David T Yeung, MBBS, PhD, BSc, FRACP, FRCPA^1,2, Timothy P Hughes, MD, MBBS, FRACP, FRCPA^1,9, Devendra Hiwase, MD, MBBS, PhD, FRACP, FRCPA^1,2,10 and Daniel Thomas, MD, PhD^1,2,10

¹Haematology, Central Adelaide Local Health Network (CALHN), Adelaide, SA, Australia
²Blood Cancer, Precision Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia
³Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia
⁴Department of Haematology, Flinders Medical Centre and University, Adelaide, SA, Australia
⁵Department of Haematology, Centre for Cancer Biology, SA Pathology, Adelaide, SA, Australia
⁶Haematology Department, Royal Perth Hospital, Perth, Australia
⁷Austin Hospital, Heidelberg, Australia
⁸Cancer Program, QIMR BERGHOFER MEDICAL RESEARCH, Herston, Brisbane, AUS
⁹South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia
¹⁰Adelaide Medical School, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia

Lakshmi Bhavani Potluri, MD¹, Vikram Dhillon, DO, MBA², Jeff Aguilar, MD, MBA³, Sushmitha Nanja Reddy, MD, MBBS⁴, Dakshin Padmanabhan, MBBS⁵, Gregory Dyson, PhD^6*, Julie Boerner^6*, Jaroslaw P. Maciejewski, M.D., Ph.D., FACP⁷ and Suresh Kumar Balasubramanian, MD^6,7

¹Wayne State University/Sinai-Grace Hospital, Farmington Hills, MI
²Department of Hematology/Oncology, Neal Cancer Center/Houston Methodist Hospital, Detroit, MI
³Department of Oncology, Karmanos Cancer Institute/Wayne State University, Windsor, ON, Canada
⁴Karmanos Cancer Institute/Department of Oncology, Wayne State University, Novi, MI
⁵St Joseph Mercy Oakland (Trinity Health) Hospital, Rochester Hills, MI
⁶Karmanos Cancer Institute/Department of Oncology, Wayne State University, Detroit, MI
⁷Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH

Alexandra Bunda, MS^1*, Hui Gao, PhD^2*, Cecelia Burgwardt, BS^3*, Christy Ingersoll^2*, Rohitash Jamwal, PhD^4*, Lenny Dang, BA^2* and Megan Wind-Rotolo^2*

¹Bristol Myers Squibb, Cambridge, MA
²Agios Pharmaceuticals, Inc., Cambridge, MA
³Metamagnetics, Inc., Westborough, MA
⁴Blueprint Medicines Corp., Cambridge, MA