Eli L. Diamond, MD^1*, Benjamin Durham, MD, PhD^2*, Ahmet Dogan, MD, PhD³, Mariko Yabe, MD, PhD^4*, Kseniya Petrova-Drus, MD, PhD^3*, Raajit K. Rampal, MD, PhD⁵, Raajit K. Rampal, MD, PhD⁵, Gary Ulaner^6*, Mario Lacouture, MD^7*, Veronica Rotemberg^8*, Anne Covey^2*, Lynn Brody^9* and Omar Abdel-Wahab, MD¹⁰

¹Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY
²Memorial Sloan Kettering Cancer Center, New York, NY
³Department of Pathology and Laboratory Medicine, Hematopathology Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁴Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY
⁵Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Institute, New York, NY
⁶Hoag Family Cancer Institute, Newport Beach, CA
⁷Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁸Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York
⁹MSKCC, New York, NY
¹⁰Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY

Lucia Masarova, MD¹, Meixian Huang^2*, Sharon Bledsoe^1*, Naveen Pemmaraju, MD¹, Tapan M. Kadia, MD¹, Prithviraj Bose, MD¹, Jo Ishizawa, MD, PhD¹, Guillermo Montalban-Bravo, MD¹, Mi-Ae Lyu^2*, Ke Zeng, MD^2*, Tara Sadeghi^3*, Ekatherine Asatiani, MD⁴, Simrit Parmar, MBBS², Christopher R. Flowers, MD, MS² and Hagop M. Kantarjian, MD¹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
³Cellenkos Inc., Houston, TX
⁴Incyte Corporation, Wilmington, DE

Yi Zhang^1*, Hu Zhou, MD^2*, Zhongxing Jiang^3*, Dengshu Wu^4*, Junling Zhuang, MD, PhD⁵, Wei Li^6*, Qian Jiang, MD⁷, Xiuli Wang^8*, Jinwen Huang^9*, Huanling Zhu^10*, Linhua Yang, MD^11*, Xin Du^12*, Fei Li^13*, Ruixiang Xia^14*, Feng Zhang^15*, Jianda Hu¹⁶, Yan Li^17*, Yu Hu, MD^18*, Jing Liu, PhD^19*, Chenghao Jin^20*, Kai Sun^21*, Zeping Zhou^22*, Shanshan Suo, MD^23*, Wenjuan Yu, MD^1* and Jie Jin, MD¹

¹Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
²Henan Cancer Hospital/The Affiliated Cancer Hospital of Zheng Zhou University, Zhengzhou, China
³The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
⁴Department of Hematology, Xiangya Hospital, Central South University, Changsha, China
⁵Peking Union Medical College Hospital,Chinese Academy of Medical Sciences, Beijing, China
⁶The First Hospital of Jilin University, Changchun, China
⁷Peking University of People's Hospital, BEIJING, China
⁸Department of Oncology Hematology, The Second Hospital of Jilin University, Changchun, China
⁹Department of Hematology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China
¹⁰Department of Hematology, West China Hospital, Sichuan University, Chengdu, China
¹¹Department of Hematology, The Second Affiliated Hospital of Shanxi Medical University, Taiyuan, China
¹²Guangdong Provincial People's Hospital, Guangzhou, China
¹³The First Affiliated Hospital of Nanchang University, Nanchang, China
¹⁴The First Affiliated Hospital of Anhui Medical University, Hefei, China
¹⁵Department of Hematology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China
¹⁶Fujian Institute of Hematology, Fujian Provincial Key Laboratory of Hematology, Fujian Medical University Union Hospital, Fuzhou, China
¹⁷Department of Hematopathology, The First Affiliated Hospital of China Medical University, Shenyang, China
¹⁸Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
¹⁹Department of Hematology, The Second Xiangya Hospital, Molecular Biology Research Center, School of Life Sciences, Hunan Province Key Laboratory of Basic and Applied Hematology, Central South University, Changsha, China
²⁰Department of Hematology, Jiangxi Provincial People's Hospital, Nanchang, China
²¹Department of Hematology, Henan Provincial People's Hospital, Zhengzhou, China
²²Department of Hematology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China
²³Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, PR China;, Hangzhou, China

Naseema Gangat, MBBS¹, Omer Karrar^1*, Maymona Abdelmagid^2*, Moazah Iftikhar^1*, Kaaren K. Reichard, MD³, Natasha Szuber, MD, MSc⁴ and Ayalew Tefferi, MD¹

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Division of Hematology, Mayo Clinic, Rochester, MN, USA., Rochester, MN
³Division of Hematopathology, Mayo Clinic, Rochester, MN
⁴Department of Hematology, Maisonneuve-Rosemont Hospital, Montreal, QC, Canada

Giacomo Coltro, MD^1,2*, Raffaella Santi, MD^3*, Giuseppe Gaetano Loscocco, MD^1,2*, Alessandro Atanasio, MD^2,4*, Paolo Cicogna, MD^2,4*, Paola Guglielmelli, MD, PhD^2,5, Umberto Gianelli, Prof^6* and Alessandro M. Vannucchi, MD^7,8*

¹Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
²CRIMM, Center for Research and Innovation of Myeloproliferative Neoplasms, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
³Pathology Section, Department of Health Sciences, University of Florence, Florence, Italy
⁴University of Florence, Florence, Italy
⁵CRIMM, Center of Research and Innovation of Myeloproliferative Neoplasms, University of Florence, AOU Careggi, Florence, Italy
⁶Department of Health Sciences, University of Milan, Milano, Italy
⁷University of Florence, CRIMM, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
⁸CRIMM, Center for Research and Innovation of Myeloproliferative Neoplasms, University of Florence, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy

Pavlina Chrysafi, MD¹, Kevin Barnum, MD, PhD^2*, Genevieve Gerhard, MD^3*, Thita Chiasakul, MD^4*, Arshit Narang^5*, Megan McNichol^6*, Nicoletta Riva, MD, PhD^7*, Walter Ageno, MD^8*, Jeffrey I. Zwicker, MD⁹ and Rushad Patell, MBBS¹⁰

¹Department of Medicine, Mount Auburn Hospital, Harvard Medical School, Cambridge, MA
²Division of Hematology/Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
³Beth Israel Deaconess Medical Center, Boston, MA
⁴Center of Excellence in Translational Hematology, Division of Hematology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand
⁵All India Institute of Medical Sciences, New Delhi, India
⁶Department of Information Systems, Division of Knowledge Services, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
⁷Department of Pathology, Faculty of Medicine and Surgery, University of Malta, Msida, Malta
⁸Department of Medicine and Surgery, University of Insubria, Varese, Italy
⁹Beth Israel Deaconess Medical Center Harvard Medical School, Boston, MA
¹⁰Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA

Sung-Yong Kim, MD, PhD^1*, Sung-Eun Lee, MD^2*, Junshik Hong, MD³, Soo-Mee Bang, MD, PhD⁴, Jinny Park^5*, Chul Won Choi^6*, Sung Hwa Bae, MD^7*, Min Kyoung Kim, MD^8* and Seug Yun Yoon^9*

¹Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Seoul, South Korea
²Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea, Republic of (South)
³Seoul National University Hospital, Seoul National University College of Medicine, Seoul, KOR
⁴Seoul National University Bundang Hospital, Seongnam-si, KOR
⁵Gil Medical Center Gachon University, Inchon, KOR
⁶Department of Internal Medicine, Korea University Medical Center, Seoul, KOR
⁷Department of Internal Medicine, Daegu Catholic, University Hospital, Daegu Catholic University School of Medicine, Daegu, KOR
⁸Yeungnam University Hospital, Daegu, Korea, Republic of (South)
⁹Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul, New Jersey, KOR

Katie Erdos^1*, Neville Lee Jr.^1*, Ahamed Lebbe^2*, Imane Bouhali^2*, Mohammed Khalid^2*, Ghaith Abu-Zeinah, MD¹, Richard T. Silver, MD¹ and Joseph M. Scandura, MD, PhD, MS¹

¹Richard T. Silver, MD Myeloproliferative Neoplasms Center, Weill Cornell Medicine, New York, NY
²Weill Cornell Medicine - Qatar, Doha, Qatar

Rami S. Komrokji, MD¹, Aaron T. Gerds, MD, MS², Claire N Harrison³, Jean-Jacques Kiladjian, MD, PhD⁴, Ruben A. Mesa, MD⁵, Prithviraj Bose, MD⁶, Fabian Sanabria^7*, Niloufar Marsousi^7*, Ana Carolina Giuseppi^8*, Huijing Jiang^8* and Francesco Passamonti^9*

¹Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
²Cleveland Clinic, Cleveland, OH
³Guy's and Saint Thomas' NHS Foundation Trust, London, United Kingdom
⁴Hopital Saint-Louis, Paris, France
⁵Wake Forest Baptist Comprehensive Cancer Center, Medical Center Blvd, Winston-Salem, NC
⁶MD Anderson Cancer Center, The University of Texas, Houston, TX
⁷Bristol Myers Squibb, Boudry, Switzerland
⁸Bristol Myers Squibb, Princeton, NJ
⁹University of Milano Statale, Milan, Italy

Giacomo Coltro, MD^1,2*, Raffaella Santi, MD^3*, Alessandro Atanasio, MD^2,4*, Paolo Cicogna, MD^2,4*, Paola Guglielmelli, MD, PhD^2,5, Umberto Gianelli, Prof^6* and Alessandro M. Vannucchi, MD^7,8*

¹Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
²CRIMM, Center for Research and Innovation of Myeloproliferative Neoplasms, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
³Pathology Section, Department of Health Sciences, University of Florence, Florence, Italy
⁴University of Florence, Florence, Italy
⁵CRIMM, Center of Research and Innovation of Myeloproliferative Neoplasms, University of Florence, AOU Careggi, Florence, Italy
⁶Department of Health Sciences, University of Milan, Milano, Italy
⁷University of Florence, CRIMM, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
⁸CRIMM, Center for Research and Innovation of Myeloproliferative Neoplasms, University of Florence, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy

Daehun Kwag^1*, Gi-June Min^1*, Sung-Soo Park^2*, Silvia Park^3*, Jae-Ho Yoon, MD¹, Byung-Sik Cho^1*, Ki-Seong Eom^1*, Yoo-Jin Kim¹, Seok Lee¹, Hee-Je Kim¹, Chang-Ki Min^1*, Seok-Goo Cho^1*, Jong-Wook Lee, MD⁴ and Sung-Eun Lee, MD^5*

¹Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
²Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea
³Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, AL, South Korea
⁴Department of Hematology, Seoul St. Mary's Hospital Catholic University of Korea, Seoul, South Korea
⁵Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Houston, TX

Miriam Kimpton, MD, MSc¹, Sonia Cerquozzi, MD², Dominique Toupin, MD^3*, Pierre Villeneuve, MD, PhD, FRCPC¹, Deborah Siegal, MD, MSc¹, Marc Carrier, MD, MSc¹ and Aurelien Delluc, MD, PhD^1*

¹The Ottawa Hospital, Ottawa, ON, Canada
²Alberta Health Services, Rochester, AB, CAN
³Centre hospitalier universitaire de Sherbrooke, Sherbrooke, Canada

Chen Jia^1*, Huan Dong^1*, Ting Sun^1*, Rongfeng Fu^1*, Renchi Yang, MD² and Lei Zhang, MD³

¹Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
²Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China
³State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Tianjin Key Laboratory of Gene Therapy for Blood Diseases, CAMS Key Laboratory of Gene Therapy for Blood Diseases, Tianjin, China

Tomoki Ito, MD, PhD¹, Teruhito Takakuwa, MD, PhD^2*, Masayuki Hino, MD, PhD^2*, Hirohisa Nakamae, MD, PhD^3* and Tadashi Matsuura, PhD^4*

¹1st. Department of Internal medicine, Kansai Medical University, Hirakata, Japan
²Department of Hematology, Osaka Metropolitan University, Osaka, Japan
³Department of Hematology, Osaka Metropolitan University Hospital, Osaka, Japan
⁴Perseus　Proteomics Inc., Tokyo, Japan

Ruben A. Mesa, MD¹, Moshe Talpaz, MD², Flora Mazerolle, MSc^3*, Boris Gorsh, PharmD^4*, Manal M'Hari, MSc^3*, Antoine Regnault, PhD^3*, Catherine Ellis, BS^4*, Zhaohui Wang, MS^4*, Molly Purser, PhD, MBA^4*, Tom Liu, MS^4*, Bryan Strouse, MS^4* and Dwaipayan Patnaik, MD, MBBS⁵

¹Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, NC
²University of Michigan Comprehensive Cancer Center, Ann Arbor, MI
³Modus Outcomes, Lyon, France
⁴GSK plc, Collegeville, PA
⁵GSK, Baar, Switzerland

Marianna Criscuolo^1*, Patrizia Chiusolo^1,2*, Luana Fianchi, MD, PhD^3*, Antonio Giordano, MD^4*, Matteo Bonanni, MD^2,5*, Alessia Di Pilla, MD^2,6*, Maria Colangelo, MD^7*, Monica Rossi, MD^8*, Gessica Minnella, MD^1*, Tanja Malara, MD^6*, Luigi Maria Larocca, MD^9*, Andrea Bacigalupo, MD¹⁰ and Livio Pagano, MD^3,11*

¹Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy
²Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche, Università Cattolica del Sacro Cuore, Rome, Italy
³Dipartimento di Scienze Radiologiche Radioterapiche ed Ematologiche, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy
⁴Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, ROMA, ITA
⁵Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, ITA
⁶Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy
⁷UOC Genetica Medica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy
⁸Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy
⁹Università Cattolica Del Sacro Cuore, Rome, ITA
¹⁰Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, ITA
¹¹Università Cattolica del Sacro Cuore, Roma, Italy

Ganesh Sivakumar, MD^1*, Shivani Handa, MD², Andrew Srisuwananukorn, MD³, Douglas Tremblay, MD², John Mascarenhas, MD^4*, Marina Kremyanskaya, MD, PhD², Yelena Ginzburg, MD², Xiaoli Wang, MD, PhD² and Ronald Hoffman, MD⁴

¹Department of Internal Medicine, Icahn School of Medicine/ Mount Sinai Morningside-West, New York, NY
²Division of Hematology & Medical Oncology, Tisch Cancer Institute/ Icahn School of Medicine at Mount Sinai, New York, NY
³Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH
⁴Department of Medicine, Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY

Zefeng Xu^1*, Ling Pan^2*, Zhenya Hong, MD^3*, Qingsong Yin, PhD^4*, Xuelan Zuo, MD^5*, Qin Wen, MD^6*, Fan Yu, MD^7*, Chunkang Chang, MD^8*, Wei Ling, MD^9*, Dong Wang^10*, Dawei Ding^10* and Zhijian Xiao, MD^1*

¹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin Institutes of Health Science, Tianjin, China
²Department of Hematology, West China Hospital of Sichuan University, Chengdu, China
³Tongji Hospital Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⁴Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China
⁵Zhongnan Hospital of Wuhan University, Wuhan, China
⁶Medical Center of Hematology, Xinqiao Hospital, State Key Laboratory of Trauma, Burn and Combined Injury, Army Medical University, Chongqing, China
⁷Beijing Tsinghua Changgung Hospital, Beijing, China
⁸Shanghai Sixth People's Hospital, Shanghai, China
⁹Guangdong Provincial People’s Hospital, Guangdong, China
¹⁰Chia Tai Tianqing Pharmaceutical Group Co., Ltd, Nanjing, China

Douglas Tremblay, MD¹, Zaker I. Schwabkey, MD², Yosef Joseph Rene Amel Riazat-Kesh, MD^1*, Grace Van Hyfte^3*, Najla H Al Ali, MS^4*, Julian Waksal, MD¹, Andrew Srisuwananukorn, MD⁵, Rami S. Komrokji, MD⁴, John Mascarenhas, MD^1* and Andrew T. Kuykendall, MD²

¹Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
²Moffitt Cancer Center, Tampa, FL
³Icahn School of Medicine At Mount Sinai, New York, NY
⁴Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
⁵Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH

Yuka Sugimoto, MD, PhD¹, Keiki Nagaharu, MD, PhD^2,3*, Eiko Oya, MD^3,4*, Kohshi Ohishi, MD, PhD⁵, Isao Tawara, MD, PhD³, Tomoki Ito, MD, PhD⁶, Akihiko Gotoh, MD, PhD⁷, Mika Nakamae, MD, PhD^8*, Fumihiko Kimura, MD, PhD⁹, Michiaki Koike, MD, PhD^10*, Keita Kirito, MD¹¹, Hideho Wada, MD, PhD^12*, Kensuke Usuki, MD, PhD¹³, Takayuki Tanaka, MD, PhD^14*, Takehiko Mori, MD, PhD^15,16*, Satoshi Wakita, MD, PhD^17*, Toshiki I Saito, MD, PhD^18*, Akiko Kada, PhD^18*, Akiko M Saito, MD, PhD^18*, Kazuya Shimoda, MD, PhD¹⁹, Toshio Kurokawa, MD, PhD^20*, Akihiro Tomita, MD, PhD^21*, Yoko Edahiro, MD, PhD^22*, Yoshinori Hashimoto, MD, PhD^14*, Hitoshi Kiyoi, MD, PhD²³, Koichi Akashi, M.D., Ph.D.^24*, Itaru Matsumura, MD, PhD²⁵, Katsuto Takenaka²⁶ and Norio Komatsu, MD, PhD,^27,28

¹Department of Hematology and Oncology, Mie University, Tsu City, Mie Prefecture, Japan
²Department of Hematology, Yokkaichi Municipal Hospital, Yokkaichi, JPN
³Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu, Japan
⁴Department of Hematology, Matsusaka Chuo General Hospital, Matsusaka, Japan
⁵Transfusion Medicine and Cell Therapy, Mie University Hospital, Tsu, Mie, JPN
⁶1st. Department of Internal medicine, Kansai Medical University, Hirakata, Japan
⁷Department of Hematology, Tokyo Medical University, Tokyo, JPN
⁸Department of Hematology, Osaka Metropolitan University Graduate School of Medicine, Osaka, JPN
⁹Division of Hematology, National Defense Med. College, Tokorozawa, JPN
¹⁰Department of Hematology, Juntendo University Shizuoka Hospital, Izunokuni, Japan
¹¹Department of Hematology and Oncology, University of Yamanashi, Chuo, Japan
¹²Department of Hematology, Kawasaki Medical School, Kurashiki, JPN
¹³NTT Medical Center Tokyo, Tokyo, Japan
¹⁴Department of Hematology, Tottori Prefectural Central Hospital, Tottori, Japan
¹⁵Division of Hematology, Keio University School of Medicine, Tokyo, Japan
¹⁶Department of Hematology, Tokyo Medical and Dental University School of Medicine, Bunkyo-Ku, JPN
¹⁷Hematology, Internal Medicine, Nippon Medical School, Tokyo, JPN
¹⁸Clinical Research Center, NHO Nagoya Medical Center, Nagoya, JPN
¹⁹University of Miyazaki, Miyazaki, Japan
²⁰Department of Hematology, Toyama Red Cross Hospital, Toyama, Japan
²¹Department of Hematology, Fujita Health University School of Medicine, Toyoake, JPN
²²Department of Hematology, Juntendo University School of Medicine, Tokyo, JPN
²³Nagoya University Graduate School of Medicine, Nagoya, Japan
²⁴Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medicine, Fukuoka, Japan
²⁵Department of Hematology and Rheumatology, Kindai University Faculty of Medicine, Osaka-Sayama, JPN
²⁶Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine, Toon, Japan
²⁷Department of Hematology, Juntendo University School of Medicine, Tokyo, Japan
²⁸PharmaEssentia Japan KK, Tokyo, Japan

Joseph Tripodi, PhD¹, Ronald Hoffman, MD², Douglas Tremblay, MD³, John Mascarenhas, MD^4*, Marina Kremyanskaya, MD, PhD⁵, Ian Novoselac^6* and Vesna Najfeld, PhD^4,7

¹Department of Pathology, Molecular and Cell-Based Medicine, The Icahn School of Medicine at Mount Sinai, Old Tappan, NJ
²Department of Medicine, Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
³Department of Hematology and Medical Oncology, Mount Sinai School of Medicine, New York, NY
⁴Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
⁵Division of Hematology & Medical Oncology, Tisch Cancer Institute/ Icahn School of Medicine at Mount Sinai, New York, NY
⁶The Department of Pathology, Molecular and Cell-Based Medicine, The Mount Sinai Hospital, New York, NY
⁷Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY

Baptiste Le Calvez^1,2*, Maxime Jullien, MD^3,4*, Jean-Hugues Dalle^5*, Cécile Renard, MD^6*, Charlotte Jubert, MD^7*, Arthur Sterin^8*, Catherine Paillard^9*, Anne Huynh, MD^10*, Sarah Guenounou, MD^11*, Benedicte Bruno^12*, Virginie Gandemer^13*, Nimrod Buchbinder^14*, Pauline Simon^15*, Cecile Pochon^16*, Anne Sirvent, MD^17*, Dominique Plantaz^18*, Justyna Kanold^19*, Fanny Rialland Battisti^20* and Audrey Grain, MD^1,2*

¹Pediatric Hematology, Nantes, France
²Nantes University, Inserm UMR 1307, CNRS UMR 6075, Angers University, CRCI2NA, Nantes - France, Nantes, France
³Inserm UMR 1307, CNRS UMR 6075 - Team 12, Nantes University, Nantes, MD, France
⁴Nantes University Hospital, NANTES, France
⁵Department of Pediatric Hematology and Immunology, University Hospital Robert Debré, Assistance Publique des Hôpitaux de Paris (APHP), Paris, France
⁶Institute of Hematology and Pediatric Oncology, Lyon, France
⁷Hématologie et oncologie pédiatrique, CHU de Bordeaux, Bordeaux Cedex, FRA
⁸APHM, La Timone Children Hospital, Department of Pediatric Hematology, Immunolog, Marseille, FRA
⁹CHRU Strasbourg, Strasbourg, FRA
¹⁰Institut Universitaire du Cancer Toulouse - Oncopole, Toulouse, France
¹¹CHU de Toulouse - Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France
¹²Chru Lille, Jeanne De Flandre Hématologie Pédiatrique, Lille, FRA
¹³CHU Hopital Sud, Rennes, FRA
¹⁴Rouen University Hospital, Rouen, FRA
¹⁵Hématologie et oncologie pédiatrique, CHRU de Besancon, Besancon, France
¹⁶Department of Hematology, Centre Hospitalier Régional Universitaire (CHRU), Vandoeuvre-les-Nancy, France
¹⁷CHU Montpellier, Montpellier, France
¹⁸CHU Grenoble, Grenoble, France
¹⁹CHU Clermont Ferrand, Clermontferrand, FRA
²⁰Hématologie et oncologie pédiatrique, CHU Hôtel Dieu, Nantes, FRA

Johannes Luebke, MD^1*, Nicole Naumann, PhD^1*, Timo Brand, MD^1*, Hans-Peter Horny, MD^2*, Martina Rudelius^2*, Karl Sotlar, MD^3*, Georgia Metzgeroth, MD^1*, Alice Fabarius, PhD^1*, Wolf-Karsten Hofmann, MD¹, Juliana Schwaab^4* and Andreas Reiter, MD⁵

¹Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany
²Institute of Pathology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany
³University Hospital, Paracelsus Medical University, Salzburg, AUT
⁴Department of Hematology and Oncology, Iii.Medizinische Klinik, Mannheim, Germany
⁵Department of Hematology and Oncology, University Medical Centre Mannheim, Mannheim, Germany

Tong-Yoon Kim^1*, Sung-Eun Lee, MD^2*, Gi-June Min^3*, Sung-Soo Park^3*, Silvia Park^4*, Jae-Ho Yoon, MD³, Byoung Sik Cho^4*, Yoo-Jin Kim³, Ki-Seong Eom^3*, Seok Lee³, Hee-Je Kim^5*, Chang-Ki Min^3*, Seok-Goo Cho^4*, Jong-Wook Lee, MD³, Jongmi Lee^6*, Myungshin Kim^7* and Ji Yoon Lee^8*

¹Department of Hematology, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea, Seoul, KOR
²Leukemia Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
³Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
⁴Department of Hematology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
⁵Catholic Hematology Hospital, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Seoul, Korea, Republic of (South)
⁶Department of Laboratory Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea, Seoul, KOR
⁷Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
⁸Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea, Seoul, Korea, Republic of (South)

Shiwei Hu^1*, Xiudi Yang, MD^1*, Jingjing Zhu, MD^1* and Jian Huang^2,3

¹Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
²Zhejiang Provincial Clinical Research Center for Hematological disorders, Hangzhou, China;, Hangzhou, China
³Department of Hematology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, PR China;, Hangzhou, China

Mael Heiblig^1*, Clement Gourguechon^2*, Philippe Guilpain^3*, Cristina Bulai Livideanu^4*, Stéphane Barete, MD, PhD^5*, Julie Agopian^6*, Fabienne Brenet, PhD^7*, Patrice Dubreuil^7*, Richard Lemal^8*, Olivier Tournilhac^9*, Louis Terriou, MD PhD^10*, David Launay, Pr^11*, Laurence Bouillet, Pr^12*, Gandhi Laurent Damaj, MD, PhD^13*, Thomas Ballul^14*, Céline Greco^15*, Laura Polivka, MD, MSc^16*, Laurent Frenzel, MD, PhD^17*, Cecile Meni^18*, Hassiba Bouktit^19*, Caroline Gaudy-Marqueste, Pr^20*, Marie Gousseff^21*, Edwige Le Mouel^22*, Antoine Neel, Pr^23*, Dana Ranta^24*, Roland Jaussaud, Pr^25*, Thierry Jo Molina, MD, PhD^26*, Julie Bruneau^27*, Ludovic Lhermitte^28*, Marie Temple^29*, Olivier Kosmider, PharmD, PhD^30*, Rose-Marie Javier^31*, Fabien Pelletier^32*, Florence Castelain^33*, Frédérique Retornaz^34*, Quentin Cabrera^35*, Patricia Zunic^36*, Marie-Pierre Gourin, MD^37*, Ewa Wierzbicka-Hainaut^38*, Jean-Francois Viallard, MD PhD^39*, Christian Lavigne^40*, Cyrille Hoarau^41*, Isabelle Durieu^42*, Sophie Dimicoli-Salazar^43*, Jose-Miguel Torregrosa-Diaz^44*, Angele Soria, Pr^45*, Michel Arock, Pr^46*, Christine Bodemer^47*, Olivier Lortholary, Pr^48*, Olivier Hermine, MD, PhD^49,50 and Julien Rossignol^51*

¹Hematology Department, Hôpital Lyon Sud, Vourles, Rhône Alpes, France
²Amiens University Hospital, Amiens, France
³Montpellier University Hospital, Montpellier, FRA
⁴Department of Dermatology, CEREMAST Toulouse, CHU Toulouse, Toulouse, France
⁵AP-HP, Pitié-salpêtrièRe Hospital, University Pierre & Mari, Paris, France
⁶Centre De Recherche En CancéRologie De Marseille - AFIRMM, Marseille, FRA
⁷Oncométabolisme dans les hémopathies malignes, Centre de Recherche en Cancérologie de Marseille, Marseille, France
⁸Centre hospitalier universitaire de Clermont-Ferrand, Clermont Ferrand, FRA
⁹CHU de Clermont-Ferrand, CLERMONT FERRAND, AURA, FRA
¹⁰Lille University Hospital, Lille, FRA
¹¹Service de médecine interne, CHRU de Lille, Lille, France
¹²Service de médecine interne, CHU de Grenoble, Grenoble, France
¹³CHU Caen, Caen, Normandy, FRA
¹⁴Service de médecine interne, Hôpital Necker-Enfants Malades, Paris, France
¹⁵Douleur et médecine palliative, Hôpital Necker-Enfants Malades, Paris, FRA
¹⁶Institut Imagine, Hôpital Necker-Enfants Malades, PARIS, FRA
¹⁷Department of Haematology, Institut Necker, Paris, FRA
¹⁸AP-HP5, Paris, FRA
¹⁹CEREMAST, Hôpital Necker-Enfants Malades, Paris, France
²⁰Service de Dermato Oncologie, Dermatologie Générale et Vénéréologie, Hôpital de la Timone, Marseille, France
²¹Médecine interne et maladies infectieuses, Centre Hospitalier Bretagne Atlantique, Vannes, France
²²Médecine Interne et Immunologie Clinique, Centre Hospitalier Universitaire de Rennes, Rennes, FRA
²³Service de Médecine Interne-Médecine Vasculaire, CHU de Nantes, Nantes, France
²⁴Hématologie, CHRU NANCY, Vandoeuvre Les Nancy, FRA
²⁵Service de médecine interne et immunologie clinique, CHRU de Nancy, Vandoeuvre-Les-Nancy, France
²⁶Necker enfants malades, APHP, Paris, Paris, France
²⁷Anatomie pathologique, Hôpital Necker-Enfants Malades, Paris, France
²⁸Laboratory of Onco-Hematology, Necker Enfants-Malades Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Université Paris Cité, Paris, France
²⁹Hématologie Biologique, Hôpital Cochin, Paris, France
³⁰Laboratory of Hematology, Université Paris Cité and Assistance Publique-Hôpitaux de Paris. Centre, Hôpital Cochin, Paris, France
³¹Service de rhumatologie, CHRU Strasbourg, Strasbourg, FRA
³²Service de Dermatologie, maladies sexuellement transmissibles, allergologie et explorations cutanées, CHU Besançon, Besançon, France
³³DERMATOLOGIE, MALADIES SEXUELLEMENT TRANSMISSIBLES, ALLERGOLOGIE ET EXPLORATIONS CUTANÉES, CHU Besançon, BesançOn, FRA
³⁴Pôle hématologie, infectiologie et médecine interne, Hôpital Européen Marseille, Marseille, France
³⁵Hématologie, CHU Sud Réunion, Saint Pierre, Reunion
³⁶Centre Hospitalier Universitaire de La Réunion - Saint-Pierre, St Pierre, France
³⁷CHU Limoges, Limoges, FRA
³⁸Unité de dermatologie Service de Dermatologie et dermato-allergologi, CHU Poitiers, Poitiers, France
³⁹Service Médecine Interne, Haut-Leveque Hospital, Pessac, France
⁴⁰Angers University Hospital, Angers, France
⁴¹Immunologie, Université de Tours, Tours, FRA
⁴²Service de Médecine Interne, Université De Lyon- Hospices Civils De Lyon, Pierre Benite, France
⁴³Hôpital Haut-Lévêque, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France
⁴⁴Hématologie, CHU Poitiers, Poitiers, France
⁴⁵Dermatologie, allergologie et médecine vasculaire, Hôpital Tenon, Paris, France
⁴⁶CHU PITIE SALPETRIERE, Paris, France
⁴⁷Necker Enfant Malades Hospital, University Paris 5, Paris, FRA
⁴⁸Medecine interne, Hôpital Necker-Enfants Malades, Paris, France
⁴⁹INSERM U1163 and CNRS 8254, Imagine Institute, Université Sorbonne Paris Cité, Paris, France
⁵⁰Department of Hematology, Hospital Necker, Assistance Publique Hôpitaux de Paris, University Paris Descartes, Paris, France
⁵¹Hématologie, NECKER ENFANTS MALADES Hospital APHP, Paris, FRA

Fabrizio Cavalca^1,2*, Ivan Civettini, MD^3,4*, Stefano Bonfanti, MD^3,4*, Carlo Gambacorti-Passerini, MD^4,5 and Elena Maria Elli, MD^6*

¹Hematology Department, San Gerardo Hospital, Monza, Italy
²University of Milan-Bicocca, Milan, Italy
³Department of Medicine and Surgery, University Milano-Bicocca, Monza, Italy
⁴Hematology Department, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy
⁵University Milano-Bicocca, Monza, Italy
⁶Hematology Division and Bone Marrow Unit, IRCCS Foundation San Gerardo dei Tintori, Monza, Italy., Monza, Italy

Rathnam K. Venkat, BA, BS¹, Robert A. Redd, MS^2*, Martin J. Aryee, PhD^2,3*, Anna E. Marneth, PhD^4,5, Baransel Kamaz, MD^6*, Chulwoo J. Kim^7*, Mohammed Wazir⁸, Lachelle D. Weeks, MD, PhD⁹, Maximilian Stahl, MD⁹, Daniel J. DeAngelo⁹, Coleman Lindsley, MD, PhD¹⁰, Marlise R. Luskin, MD, MSCE¹⁰, Gabriela S. Hobbs, MD¹¹ and Joan How, MD^5,9

¹Tufts University School of Medicine, Boston, MA
²Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
³Broad Institute of MIT and Harvard, Cambridge, MA
⁴Department of Laboratory Medicine, Division Laboratory of Hematology, Radboud University Medical Center, Nijmegen, Netherlands
⁵Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Boston, MA
⁶Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
⁷Department of Medicine, Division of Hematology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
⁸Umass Chan Medical School, Worcester, MA
⁹Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
¹⁰Dana-Farber Cancer Institute, Boston, MA
¹¹Division of Hematology/Oncology, Massachusetts General Hospital, Boston, MA

Atulya Aman Khosla, MBBS¹, Nitya Batra, MBBS^2*, Rohit Singh, MD^3*, Karan Jatwani, MBBS^4*, Akshee Batra, MBBS^5*, Yanjia Zhang^6*, Zhenwei Zhang^7*, Md Ashfaq Ahmed^6*, Mukesh Roy^7*, Venkataraghavan Ramamoorthy^6*, Muni Rubens, MD, PhD^6*, Anshul Saxena^6* and Diego Adrianzen Herrera, MD³

¹Department of Internal Medicine, Beaumont Hospital (Royal Oak), Troy, MI
²William Beaumont Hospital, Royal Oak, MI
³Division of Hematology and Oncology, Larner College of Medicine at the University of Vermont, Burlington, VT
⁴Roswell Park Comprehensive Cancer Center, Buffalo
⁵Department of Internal Medicine, University of Vermont Medical Center, Winooski, VT
⁶Baptist Health South Florida, Miami
⁷Baptist Health South Florida, Miami, FL

Danijela Lekovic, MD, PhD¹, Jelena Ivanovic^2*, Isidora Arsenovic, MD^3*, Mihailo Smiljanic, MD^3*, Vladan P. Cokic^4* and Andrija Bogdanovic, Professor^1,3*

¹Faculty of Medicine, University of Belgrade, Belgrade, Serbia
²Clinic for Hematology, University Clinical Center of Serbia, Belgrade, Serbia
³Clinic of Hematology, University Clinical Center Serbia, Belgrade, Serbia
⁴Department of molecular oncology, Institute for Medical Research, National Institute of Republic of Serbia, University of Belgrade, Belgrade, Serbia, Serbia

Roberto Latagliata^1*, Gianluca Cristiano, MD^2*, Dorela Lame, MD^3*, Alda Strazimiri, MD^4*, Fabrizio Cavalca^5*, Lorenzo Rizzo, MD^6*, Giulia De Luca, MD^7*, Simone Zoletto, MD^8*, Vincenzo Federico, MD^9*, Daniele Cattaneo, MD^10*, Annalisa Biagi, MD^11*, Monica Crugnola, MD^12*, Pasquale Niscola, MD^13*, Raffaele Palmieri, MD^14*, Anna Lina Piccioni, MD^15*, Olga Mulas, MD^16*, Beatrice Esposito Vangone, MD^17*, Michelina Santopietro, MD^18*, Ida Carmosino, MD^19*, Alessandra Iurlo, MD, PhD^20*, Nicola Di Rienzo, MD^21*, Gianni Binotto, MD^22*, Prassede Salutari, MD^23*, Marta Riva, MD^24*, Massimiliano Bonifacio, MD^25*, Elena Maria Elli, MD^26*, Antonio Curti, MD, PhD²⁷ and Antonella Poloni, MD^28*

¹Hematology, Belcolle Hospital, Rome, Italy
²Department of Medical and Surgical Sciences, Institute of Hematology "L. and A. Seràgnoli", University of Bologna, Bologna, Italy
³Hematology, AOU Marche - Politecnic University Marche, Ancona, Italy
⁴Department of Engineering for Innovation Medicine, Section of Innovation Biomedicine, Hematology Area, University of Verona, Verona, Italy
⁵Hematology Department, San Gerardo Hospital, Monza, Italy
⁶Department of Hematology and Oncology, Niguarda Cancer Center, ASST Ospedale Nig, Milan, Illinois, ITA
⁷UOC Ematologia Clinica, Ospedale Civile "Santo Spirito", Pescara, Italy
⁸Hematology Unit, Department of Medicine, University of Padova, Padova, Italy
⁹Hematology, Vito Fazzi Hospital, Lecce, Italy
¹⁰Hematology, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy
¹¹S.M. Goretti Hospital – Polo Pontino “Sapienza” University - Latina, Latina, Italy
¹²Hematology Unit and BMT, University Hospital of Parma, Parma, Italy
¹³Hematology Unit, Sant'Eugenio Hospital, Rome, Italy
¹⁴Department of Onco-Hematology, Fondazione Policlinico Tor Vergata, Rome, Italy
¹⁵Dipartimento di Ematologia, Azienda Ospedaliera San Giovanni Addolorata, Rome, Italy
¹⁶Department of Medical Sciences and Public Health, University of Cagliari, Businco Hospital, Cagliari, Italy
¹⁷UOC Ematologia, Azienda ospedaliero-universitaria Senese, Siena, Italy
¹⁸Hematology and Hematopoietic Stem Cells Transplant Unit, AO San Camillo-Forlanini, Rome, Italy
¹⁹Hematology, Department of Translational and Precision Medicine, Azienda Ospedaliera Policlinico Umberto I, Sapienza University of Rome, Rome, Italy
²⁰Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy
²¹UO EMATOLOGIA, ASL LECCE, OSPEDALE V. FAZZI, Lecce, Italy
²²Department of Medicine, Hematology and Clinical Immunology, University of Padua, Padua, Italy
²³Department of Hematology, Ospedale Civile Spirito Santo, Pescara, Pescara, Italy
²⁴Department of Hematology, ASST Grande Ospedale Metropolitano Niguarda Cancer Center, Milano, Italy
²⁵Department of Medicine, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy
²⁶Fondazione IRCCS, San Gerardo dei Tintori, Monza, Monza, Italy
²⁷IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia “Seràgnoli”, Bologna, Italy
²⁸Hematology, AOU Marche - Politecnic University Marche - Ancona, Ancona, ITA

Nico Gagelmann^1*, Anita Badbaran^2*, Christine Wolschke^1*, Mathias Schäfersküpper^3*, Dietlinde Janson^4*, Francis A. Ayuk, MD^5*, Boris Fehse, PhD^6* and Nicolaus Kroeger, MD¹

¹Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
²Department of stem cell transplantation, University Hospital Hamburg Eppendorf, Hamburg, DEU
³University Medical Center Hamburg-Eppendorf, Hamburg, Germany
⁴Department of Stem Cell Transplantation, University Medical Center Hamburg Eppendorf, Hamburg, DEU
⁵Department of Stem Cell Transplantation with Research Department Cell and Gene Therapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
⁶University Medical Center Hamburg-Eppendorf, Hamburg, DEU