Matthew S. Davids, MD¹, Benjamin L. Lampson, MD, PhD¹, Svitlana Tyekucheva, PhD^2*, Jennifer L. Crombie, MD³, Samuel Ng, MD, PhD^1*, Austin I. Kim, MD⁴, Matthew Weinstock, MD⁵, Jessica Lowney^4*, Samantha Pazienza^1*, Josie Montegaard, NP^4*, Victoria Patterson, BSN, RN^1*, Caron A. Jacobson, MD^1*, Ann S. LaCasce, MD, MSc¹, Philippe Armand, MD, PhD^1*, Jon E. Arnason, MD⁵, David C. Fisher, MD^1* and Jennifer R. Brown, MD, PhD^1*

¹Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
²Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard T.H. Chan School of Public Health, Boston, MA
³Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA
⁴Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
⁵Department of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA

Lydia Scarfo^1*, Silvia Heltai^2*, Elisa Albi^3*, Eloise Scarano^3*, Luana Schiattone^3*, Lucia Farina^4*, Gianluca Gaidano⁵, Marina Deodato^6*, Andrea Ferrario^7*, Marina Motta^8*, Gianluigi Reda, MD^9*, Rosaria Sancetta, MD^10*, Marta Coscia, MD, PhD^11*, Marco Ladetto, MD¹², Luca Laurenti, MD^13*, Marzia Varettoni^14*, Eleonora Perotta^2*, Antonella Capasso^3*, Pamela Ranghetti^2*, Maria Colia^3* and Paolo Ghia, MD, PhD¹⁵

¹Strategic Research Program on CLL and Laboratory of B-cell Neoplasia, Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Milano, Italy
²Laboratory of B-cell Neoplasia, IRCCS Ospedale San Raffaele, Milano, Italy
³Strategic Research Program on CLL, IRCCS Ospedale San Raffaele, Milano, Italy
⁴Division of Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy
⁵Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy
⁶Department of Hematology, Niguarda Cancer Center, Niguarda Hospital, Milano, Italy
⁷Hematology Unit, ASST dei Sette Laghi-Ospedale di Circolo di Varese, Varese, Italy
⁸Department of Hematology, ASST Spedali Civili di Brescia, Brescia, Italy
⁹Oncohematology Department, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy
¹⁰Hematology Unit, Ospedale dell'Angelo, Venizia-Mestre, Italy
¹¹Division of Hematology, A.O.U. Città della Salute e della Scienza di Torino and Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy
¹²Division of Hematology, Azienda Ospedaliera SS Antonio e Biagio e Cesare Arrigo, Alessandria, ITA
¹³Institute of Hematology, Università Cattolica del Sacro Cuore - Policlinico A. Gemelli, Roma, Italy
¹⁴Fondazione IRCCS Policlinico S. Matteo University of Pavia, Pavia, Italy
¹⁵Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Milano, MI, Italy

Mariela Sivina^1*, Nitin Jain, MD², Ekaterina Kim, Ph.D^3*, Tapan M. Kadia, MD², Zeev E. Estrov, MD², Maro Ohanian, DO^3*, Michael Andreeff, MD, PhD³, Mathew Thomas^3*, Philip A. Thompson, MB, MS³, Hagop M. Kantarjian, MD², Michael J. Keating, MBBS⁴, Susan M. O'Brien, MD⁵, William G. Wierda, MD, PhD³, Alessandra Ferrajoli, MD² and Jan A. Burger, MD, PhD³

¹Department of Leukemia, UT M.D. Anderson Cancer Center, Houston, TX
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Leukemia, The University of Texas, MD Anderson Cancer Center, Houston, TX
⁴Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX
⁵University of California Irvine, Chao Family Comprehensive Cancer Center, Irvine, CA

John N. Allan, MD¹, Tait Shanafelt, MD², Adrian Wiestner, MD, PhD^3*, Carol Moreno, MD, PhD^4*, Susan M. O'Brien, MD⁵, Esteban Braggio, PhD⁶, Emily Liu, MS^7*, James P. Dean, MD, PhD⁷, Dominic Lai, PharmD^7* and Inhye E. Ahn, MD³

¹Weill Cornell Medicine, New York, NY
²Stanford University Medical Center, Stanford, CA
³National Heart, Lung, and Blood Institute, Bethesda, MD
⁴Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain
⁵University of California Irvine, Chao Family Comprehensive Cancer Center, Irvine, CA
⁶Mayo Clinic, Phoenix, AZ
⁷Pharmacyclics LLC, an AbbVie Company, Sunnyvale, CA

Jan A. Burger, MD, PhD¹, Tadeusz Robak, MD PhD², Fatih Demirkan, MD³, Osnat Bairey, MD^4*, Carol Moreno, MD, PhD^5*, David Simpson, MBChB, FRACP, FRCPA⁶, Talha Munir, MBBS^7*, Don A. Stevens, MD⁸, Sandra Dai, PhD, MS^9*, Leo W. K. Cheung, PhD^9*, Kevin Kwei, PhD^9*, Indu Lal, MD^9*, Emily Hsu, PhD^9*, Thomas J. Kipps, MD, PhD¹⁰ and Alessandra Tedeschi, MD^11*

¹Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Hematology, Medical University of Lodz, Copernicus Memorial Hospital, Lodz, Poland
³Department of Hematology, Dokuz Eylul University, Izmir, Turkey
⁴Rabin Medical Center, Beilinson Hospital and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⁵Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain
⁶North Shore Hospital, Auckland, New Zealand
⁷St James University Hospital, Leeds, United Kingdom
⁸Norton Cancer Institute, Louisville, KY
⁹Pharmacyclics LLC, an AbbVie Company, Sunnyvale, CA
¹⁰University of California, San Diego, Moores Cancer Center, La Jolla, CA
¹¹Niguarda Hospital, Milano, Italy

Andy C. Rawstron, PhD^1*, Peter Hillmen, MBChB, FRCP, FRCPath, PhD², Shanna Maycock, BSc, MSc^3*, Nichola Webster^1*, Kristian Brock, PhD^3*, Rebecca H. Boucher, BSc, MSc, PhD^3*, Francesca Yates, PhD^3*, Rebecca Jarvis, BSc^3*, Surita Dalal, PhD^4*, Ruth M. de Tute, PhD, FRCPath^5*, Paul Moss, MBBS, PhD, FRCP⁶, Donald Macdonald, MBChB, MD, FRCP, PhD, FCRPath^7*, Piers Patten, MD, PhD⁸, Christopher Fegan^9*, Andrew Pettitt, MA, MB BChir, PhD, MRCP, MRCPath^10*, Christopher P. Fox, MD, PhD^11*, Adrian Bloor, PhD, FRCP, FRCPath^12*, Oonagh Sheehy, MB BCh BAO, MRCP, FRCPath^13* and Peter Hillmen, MBChB, PhD^14*

¹Haematological Malignancy Diagnostic Service, St. James’s University Hospital, Leeds, United Kingdom
²Department of Haematology, St. James's University Hospital, Leeds, United Kingdom
³Cancer Research UK Clinical Trials Unit, University of Birmingham, Birmingham, United Kingdom
⁴HMDS, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
⁵Haematological Malignancy Diagnostic Service, St. James's University Hospital, Leeds, United Kingdom
⁶Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom
⁷Imperial College Healthcare NHS Trust, London, United Kingdom
⁸King’s College London and King’s College Hospital NHS Foundation Trust, London, United Kingdom
⁹Cardiff and Vale University Health Board, Cardiff, United Kingdom
¹⁰Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, United Kingdom
¹¹Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom
¹²The Christie Hospital NHS Foundation Trust, Manchester, United Kingdom
¹³Belfast HSC Trust, Belfast, United Kingdom
¹⁴St. James's University Hospital, Institute of Oncology, Leeds, United Kingdom

Philip A. Thompson, MB, MS¹, Alessandra Ferrajoli, MD¹, Nitin Jain, MD², Yan Wang^1*, Christine B Peterson^3*, Naveen Garg, MD^4*, Chongjuan Wei, PhD^1*, Ana Ayala, RN^1*, Tapan M. Kadia, MD⁵, Prithviraj Bose, MD⁶, Naveen Pemmaraju, MD¹, Nicholas J. Short, MD⁶, Michael J. Keating, MBBS¹ and William G. Wierda, MD, PhD¹

¹Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX
²Associate Professor of Medicine Department of Leukemia The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Biostatistics, UT MD Anderson Cancer Center, Houston
⁴Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Department of Leukemia, M.D. Anderson Cancer Center, Houston, TX
⁶Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Leylah Azali, PharmD^1*, Lindsay Hazelden, PharmD^1*, Tracy Wiczer, PharmD^1*, Marilly Palettas^2*, Rebekah Thomas^2*, Connor Aossey^2*, James S. Blachly, MD³, Michael R. Grever, MD³, Adam S. Kittai, MD³, Kerry A. Rogers, MD⁴, John C. Byrd, MD³, Jennifer A. Woyach, MD³, Daniel Addison, MD^2* and Seema A Bhat, MD³

¹Department of Pharmacy, The Ohio State University, Columbus, OH
²The Ohio State University, Columbus, OH
³Division of Hematology, The Ohio State University, Columbus, OH
⁴Division of Hematology, Ohio State University Hospital, Columbus, OH

Natalie F. Uy, MD¹, Edward Pequignot^2*, Noelle V. Frey, MD, MS³, Megan Davis, PhD^4*, Elizabeth O. Hexner, MD^5*, Stephen J. Schuster, MD⁶, Saar Gill, MD, PhD⁴, Alison W. Loren, MD⁷, Stephan A Grupp, MD, PhD⁸, J. Joseph Melenhorst, PhD^4,9, Simon F Lacey, PhD⁴, Joseph A Fraietta, PhD^10,11*, Joan Gilmore, BS^4*, Lester Lledo, RN, NP^12*, Wei-Ting Hwang, PhD^10*, Don L. Siegel, MD, PhD¹³, Bruce L Levine, PhD⁴, Carl H June, MD¹⁴ and David L. Porter, MD¹⁵

¹Hospital Medicine/Department of Medicine, University of Pennsylvania, Seattle, WA
²University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
³Division of Hematology and Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
⁴Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA
⁵Cell Therapy and Transplant, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
⁶Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA
⁷Division of Hematology-Oncology/Department of Medicine, Perelman Center for Advanced Medicine, Philadelphia, PA
⁸Children's Hospital of Philadelphia, Philadelphia, PA
⁹Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
¹⁰Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
¹¹Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA
¹²Center for Cellular Immunotherapies (CCI), The University of Pennsylvania, Philadelphia, PA
¹³Center for Cellular Immunotherapies, Univ. of PA Med. Ctr., Philadelphia, PA
¹⁴Center for Cellular Immunotherapies (CCI), The University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA
¹⁵Cell Therapy and Transplant, Abramson Cancer Center and Hematology-Oncology Division, University of Pennsylvania, Philadelphia, PA

Adrian Wiestner, MD, PhD¹, Paolo Ghia, MD, PhD², John C. Byrd, MD³, Inhye E Ahn, MD¹, Carol Moreno, MD, PhD^4*, Susan M. O'Brien, MD⁵, Daniel Jones, MD, PhD⁶, Leo W. K. Cheung, PhD^7*, Elizabeth Chong, PhD^7*, Kevin Kwei, PhD^7*, James P. Dean, MD, PhD⁷, Danelle F. James, MD, MAS⁷ and Jennifer A. Woyach, MD⁶

¹Laboratory of Lymphoid Malignancies, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
²Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Milano, MI, Italy
³Division of Hematology, The Ohio State University, Columbus, OH
⁴Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain
⁵UCI Cancer Center, Orange, CA
⁶The Ohio State University Comprehensive Cancer Center, Columbus, OH
⁷Pharmacyclics LLC, an AbbVie Company, Sunnyvale, CA

Paula A. Lengerke Diaz, MD¹, Michael Y. Choi, MD^2,3*, Eider F. Moreno Cortes, MD^4*, Jose V. Forero, MD^4*, Juliana Velez-Lujan, Ph.D.^5*, Carlos I. Amaya-Chanaga, MD^6*, Thomas Kipps, MD, PhD^2,3* and Januario E. Castro, MD⁴

¹Division of Hematology, Mayo Clinic, Scottsdale, AZ
²Moores Cancer Center, UCSD, La Jolla, CA
³CLL Research Consortium (CRC), UCSD, San Diego, CA
⁴Division of Hematology, Mayo Clinic, Phoenix, AZ
⁵UCSD-Moores Cancer Center, La Jolla, CA
⁶Eisai Inc, Woodcliff Lake, NJ

Jayant Narang, MD^1*, Surabhi Bajpai, MD^2*, Rudresh Rajnikant Jarecha, MBBS, MD³, Christiana Caplan, BS^3*, Dana Macdonald^4*, Gabriele Padrella^4*, Manish Sharma, MD^5* and Bruce D. Cheson, MD⁶

¹Parexel international, Rochester, NY
²Parexel international, Billerica, MA
³PAREXEL International, Billerica, MA
⁴Parexel, Billerica, MA
⁵PAREXEL Informatics, Hyderabad, India
⁶Lymphoma Research Foundation, New York

Rafael Bejar, MD, PhD^1,2, Hongying Zhang, MD, PhD^1*, Nasrin Rastgoo, PhD^1*, Khalid Benbatoul, BS^1*, Yuying Jin, PhD^1*, Matthew Thayer, BS.^1*, Susan Sheng, PhD^1*, Gregory k Chow, BA, MBA^3*, Victor Montalvo-Lugo^1*, Jotin Marango, MD^1*, Stephen B Howell, MD² and William G Rice, PhD¹

¹Aptose Biosciences, Inc., San Diego, CA
²Moores Cancer Center, University of California San Diego, La Jolla, CA
³Aptose Biosciences Inc., Burlingame, CA

Wei Xu^1*, Shenmiao Yang^2*, Constantine S. Tam, MBBS, MD^3,4,5,6*, John F. Seymour, MBBS^3,6,7, Keshu Zhou, MD, PhD^8*, Stephen Opat, MBBS (Hons), FRACP, FRCPA⁹, Lugui Qiu, MD¹⁰, Mingyuan Sun^11*, Tingyu Wang^11*, Judith Trotman, FRACP^12,13, Ling Pan, MD, PhD^14*, Sujun Gao^15*, Jianfeng Zhou, MD, PhD^16*, Daobin Zhou, MD, PhD^17*, Jun Zhu¹⁸, Yuqin Song, MD, PhD^19*, Jianda Hu, MD, PhD²⁰, Ru Feng²¹, Haiwen Huang^22*, Zhiyue Huang^23*, Huafei Lu^23* and Jianyong Li, MD, PhD¹

¹The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
²Peking University People's Hospital, Peking University Institute of Hematology, Beijing, China
³Peter MacCallum Cancer Centre & Royal Melbourne Hospital, Melbourne, Australia
⁴University of Melbourne, Parkville, VIC, Australia
⁵St Vincent's Hospital, Fitzroy, Australia
⁶Victorian Comprehensive Cancer Centre, Melbourne, Australia
⁷University of Melbourne, Melbourne, Australia
⁸Department of Hematology, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China
⁹Monash Health, Monash University, Clayton, Australia
¹⁰National Clinical Research Center for Blood Diseases, State Key Laboratory of Experimental Hematology, Blood Diseases Hospital & Institute of Hematology, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
¹¹Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
¹²Concord Repatriation General Hospital, Concord, Australia
¹³University of Sydney, Sydney, Australia
¹⁴West China Hospital of Sichuan University, Chengdu, China
¹⁵The First Hospital of Jilin University, Changchun, China
¹⁶Tongji Hospital, Tongji Medical College, Wuhan, China
¹⁷Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
¹⁸Peking University Cancer Hospital & Institute (Beijing Cancer Hospital), Beijing, China
¹⁹Department of Lymphoma, Peking University Cancer Hospital & Institute (Beijing Cancer Hospital), Beijing, China
²⁰Fujian Medical University Union Hospital, Fuzhou, China
²¹Nanfang Hospital of Southern Medical University, Guangzhou, China
²²The First Hospital of Soochow University, Suzhou, China
²³BeiGene (Beijing) Co., Ltd., Beijing, China

Suchitra Sundaram, MD^1*, Cory Mavis, MSc^1,2*, Juan J Gu, PhD^1,2*, Pallawi Torka, MD^1* and Francisco J. Hernandez-Ilizaliturri, MD^2,3

¹Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY
²Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY
³Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY

John F. Seymour, MBBS¹, John G. Gribben, MD, DSc, FRCP, FMedSci, FRCPath², Matthew S. Davids, MD³, Anthony Mato, MD^4*, Jeff P Sharman, MD⁵, Aimee Cyr^6*, Cynthia Bartkus^6*, German Pena, MD^6*, Michelle Boyer^7*, Simon Sharmokh, MPH, PharmD^8*, Tanya S Rosenberg, MD^6* and William G. Wierda, MD, PhD⁹

¹Peter MacCallum Cancer Centre, Royal Melbourne Hospital, and University of Melbourne, Melbourne, Victoria, Australia
²Barts Health NHS Trust Barts and The London School of Medicine, Queen Mary University of London, London, United Kingdom
³Dana-Farber Cancer Institute, Boston, MA
⁴University of Pennsylvania, Philadelphia, PA
⁵Willamette Valley Cancer Institute and US Oncology Research, Eugene, OR
⁶AbbVie, Inc., North Chicago, IL
⁷Genentech, Inc., South San Francisco, CA
⁸AbbVie Inc., North Chicago, IL
⁹Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX

Ismini Halmer^1*, Alexandra da Palma Guerreiro, PhD^1*, Laura Beckmann, MD^1*, Christian Reinhardt, MD^2*, Hamid Kashkar^3*, Michael Hallek⁴ and Lukas P. Frenzel, MD^1*

¹University of Cologne, Department of Internal Medicine I, Center of Integrated Oncology Cologne-Bonn, Germany, Cologne, Germany
²Department I of Internal Medicine and Center of Integrated Oncology Cologne-Bonn, German CLL Study Group, University Hospital of Cologne, Koeln, Germany
³Med. Microbiol. and Immunol. University of Cologne, Köln, NR, DEU
⁴Department of Internal Medicine I, Cologne Lymphoma Working Group, University Hospital of Cologne, Cologne, Germany