-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

641. CLL: Biology and Pathophysiology, excluding Therapy: Poster II

Program: Oral and Poster Abstracts
Type: Poster
Hematology Disease Topics & Pathways:
Adult, antibodies, apoptosis, Biological, Leukemia, survivorship, CLL, Diseases, Lymphoma (any), cell regulation, Combinations, Therapies, Adverse Events, B-Cell Lymphoma, Biological Processes, DNA damage, DNA repair, Technology and Procedures, epigenetics, Plasma Cell Disorders, Lymphoid Malignancies, Study Population, Clinically relevant, genetic profiling, genomics, Myeloid Malignancies, imaging, flow cytometry, integrative -omics, NGS, microenvironment, RNA sequencing, pathways, proteomics
Sunday, December 6, 2020: 7:00 AM-3:30 PM

Sutapa Sinha, PhD1, Wei Ding, MD, PhD1, Tammy Price-Troska, BS1*, Reona Sakemura, MD, PhD1, Shulan Tian, MS, PhD2*, Charla R. Secreto1*, Xiaosheng Wu, MD1*, Timothy G. Call, MD1, Rong He, MD3, Sameer A. Parikh, MD1, Yucai Wang, MD, PhD4, Jose F. Leis, MD, PhD5, Huihuang Yan, PhD2*, Karen Rech, MD6*, Amber B. Koehler, PA-C, MS1*, Daniel L. Van Dyke, PhD3, Minetta C. Liu, MD7*, Susan L. Slager, PhD2*, Esteban Braggio, PhD8, Stephen M. Ansell, MD, PhD9, Saad S. Kenderian, MD1 and Neil E. Kay, MD1

1Division of Hematology, Mayo Clinic, Rochester, MN
2Department of Health Sciences Research, Mayo Clinic, Rochester, MN
3Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
4Division of Hematology, Rutgers New Jersey Medical School, Rochester, MN
5Division of Hematology and Medical Oncology, Mayo Clinic Health System, Phoenix, AZ
6Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
7Department of Oncology / Laboratory Medicine & Pathology, Mayo Clinic, Rochester
8Division of Hematology/Oncology, Mayo Clinic, Scottsdale, AZ
9Mayo Clinic, Rochester, MN

Yiming Wu, PhD1*, Meiling Jin, PhD1*, Kevyn Hart, BS1*, Aijun Liao, MD, PhD1*, Stacey M. Fernandes, BS2*, Tinisha McDonald, BS3*, Lucy Brown, PhD4*, Daniel Roeth, PhD5*, Markus Kalkum, PhD5*, Raju Pillai, MD6*, Jianjun Chen, PhD1, Jennifer R Brown, MD, PhD7, Steven T. Rosen, MD8, Tanya Siddiqi, MD9 and Lili Wang, MD, PhD1,2

1Department of Systems Biology, Beckman Research Institute, City of Hope, Monrovia, CA
2Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
3Hematogic Malignancies Translational Science, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA
4Analytical Cytometry Core, City of Hope, Duarte, CA
5Department of Molecular Imaging & Therapy, City of Hope, Duarte, CA
6Department of Pathology, City of Hope, Duarte, CA
7CLL Center, Dana-Farber Cancer Institute, Boston, MA
8Beckman Research Institute, City of Hope, Duarte, CA
9Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA

Johannes Bloehdorn, MD1*, Andrejs Braun, PhD2*, Billy Michael Chelliah Jebaraj, PhD1*, Amaro Taylor-Weiner, PhD3*, Sandra Robrecht, PhD4*, Julia Krzykalla, PhD5*, Karlheinz Holzmann, PhD6*, Harvey Johnston, PhD7*, Tetyana Klymenko, PhD8*, Barbara Eichhorst, MD4, Ru-Fang Yeh, PhD9*, Martin Weisser, MD10*, Jennifer Edelmann, MD, PhD1, Kirsten Fischer, MD4*, John G. Gribben, MD, DSc, FRCP, FMedSci, FRCPath2, Dan A. Landau, MD, PhD11,12, Donna S. Neuberg, ScD13, Mark S Cragg, PhD7,14*, Axel Benner5*, Michael Hallek, MD4*, Catherine J. Wu, MD3,15,16,17, Hartmut Döhner1, Stephan Stilgenbauer, MD1 and Daniel Mertens, PhD1,18*

1Department of Internal Medicine III, University Hospital Ulm, Ulm, Germany
2Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom
3Broad Institute of MIT and Harvard, Cambridge, MA
4Department I of Internal Medicine and Center of Integrated Oncology Aachen, Bonn, Cologne, Duesseldorf, University of Cologne, Cologne, Germany
5Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany
6Genomics Core Facility, Ulm University, Ulm, Germany
7Cancer Research UK Centre and Experimental Cancer Medicine Centre, University of Southampton, Southampton, United Kingdom
8Sheffield Hallam University, Sheffield, United Kingdom
9Biostatistics, Genentech Inc., South San Francisco, CA
10Roche Innovation Center Munich, Roche Pharma Research and Early Development, Penzberg, Germany
11Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY
12New York Genome Center, New York, NY
13Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
14Centre for Cancer Immunology, University of Southampton, Southampton, United Kingdom
15Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
16Department of Internal Medicine, Brigham and Women’s Hospital, Boston, MA
17Harvard Medical School, Boston, MA
18German Cancer Research Center (DKFZ), Heidelberg, Germany

Salma Parvin, PhD1*, Aditi Aryal, BA2*, Matthew S. Davids, MD3 and Anthony G. Letai, MD, PhD4

1Department of Medical Oncology, Dana Farber Cancer Institute, Brighton, MA
2Dana Farber Cancer Institute, Boston, MA
3Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
4Department of Medical Oncology, Dana-Farber Cancer Institute & HMS, Boston, MA

Ya Zhang, MD1,2*, Xinting Hu, MM1,2*, Yang Han, MM1,2*, Xiangxiang Zhou, MD1,2*, Na Chen, MD2*, Peipei Li, PhD1,2*, Kang Lu, PhD1,2* and Xin Wang, MD, PhD1,2

1Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China
2Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China

Shulan Tian, MS, PhD1*, Hanyin Wang, MD2*, Timothy G. Call, MD3, Eric W. Klee, PhD4*, Minetta C. Liu, MD5*, Erik Jessen, PhD1*, Sameer A. Parikh, MD3, Yucai Wang, MD, PhD6, Saad S. Kenderian, MD3, Jose F. Leis, MD, PhD7, Min Shi, MD, PhD8, Eli Muchtar, MD3*, Daniel L. Van Dyke, PhD8, Amber B. Koehler, PA-C, MS3*, Neil E. Kay, MD3, Susan L. Slager, PhD1*, Esteban Braggio, PhD9, Huihuang Yan, PhD1* and Wei Ding, MD, PhD3

1Department of Health Sciences Research, Mayo Clinic, Rochester, MN
2Department of Hospital Medicine, Mayo Clinic Health System, Mankato, MN
3Division of Hematology, Mayo Clinic, Rochester, MN
4Center for Individualized Medicine, Department of Health Sciences Research, Mayo Clinic, Rochester, MN
5Department of Oncology / Laboratory Medicine & Pathology, Mayo Clinic, Rochester
6Division of Hematology, Rutgers New Jersey Medical School, Rochester, MN
7Division of Hematology and Medical Oncology, Mayo Clinic Health System, Phoenix, AZ
8Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
9Division of Hematology and Medical Oncology, Mayo Clinic, Phoenix, AZ

Jonathan S. Wall, PhD1*, R. Eric Heidel, PhD2*, Alan Stuckey3*, Emily B. Martin, PhD1*, Tina Richey, MS3*, Angela Williams, MS1*, James S. Foster, MS3*, Bryan Whittle4*, Yitong Fu, MD4*, Dustin Powell, MD4*, Ronald H. Lands, MD1, Spencer Guthrie5* and Stephen J. Kennel, PhD1*

1Department of Medicine, University of Tennessee Medical Center, Knoxville, TN
2Surgery, University of Tennessee Medical Center, Knoxville, TN
3Medicine, University of Tennessee Medical Center, Knoxville, TN
4Radiology, University of Tennessee Medical Center, Knoxville, TN
5Attralus Bio, South San Francisco, CA

Akiva Diamond, MD1, Wyatt P. Bensken, BS2*, Weichuan Dong, Ph.D.2*, Sarah C. Markt, ScD, MPH2*, Siran M. Koroukian, Ph.D.2* and Paolo Caimi, MD3

1Dan L Duncan Comprehensive Cancer Center at Baylor St. Luke's Medical Center, Houston, TX
2Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH
3University Hospitals Seidman Cancer Center, Cleveland, OH

Claudio Giacinto Atene1*, Rossana Maffei2, Stefania Fiorcari3*, Silvia Martinelli3*, Patrizia Zucchini3*, Monica Maccaferri2*, Giulia Debbia4*, Leonardo Potenza4*, Mario Luppi4* and Roberto Marasca4

1Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy
2Hematology Unit, A.O.U of Modena-Policlinico Department of Oncology and Hematology, Italy, Modena, Italy
3Department of Medical and Surgical Sciences, Hematology Unit, University of Modena and Reggio Emilia, Modena, Italy
4Department of Medical and Surgical Sciences, Section of Hematology, University of Modena and Reggio Emilia, Modena, Italy

Maria Teresa Voso, MD1, Tatjana Pandzic, PhD2,3*, Michail Iskas, MD, MSc4*, Marija Denčić-Fekete5*, Eleonora De Bellis6*, Lydia Scarfo7,8*, Viktor Ljungström3,9*, Giovanni Del Poeta, MD10, Pamela Ranghetti7,8*, Stamatia Laidou11*, Giulia Falconi, PhD12*, Silvia Imbergamo, MD13*, Chiara Salvetti, MD14*, Antonella Zucchetto, PhD15*, Niki Stavroyianni16*, Lucia Cavelier, PhD9,17*, Paolo Ghia, MD, PhD7,8, Kostas Stamatopoulos, MD18, Emiliano Fabiani, PhD19* and Panagiotis Baliakas, MD3,20*

1University of Rome Tor Vergata, Rome, Italy
2Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, SWE
3Department of Clinical Genetics, Uppsala University Hospital, Uppsala, Sweden
4Hematology Department & HCT Unit, G. Papanikolaou Hospital, Thessaloniki, Greece
5Institute for pathology, Medical Faculty, Belgrade, Serbia
6Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
7Strategic Research Program in CLL, Division of Experimental Oncology, IRCCS, Milan, Italy
8San Raffaele Hospital and Università Vita-Salute San Raffaele, Milan, Italy
9Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden
10Hematology, Department of Biomedicine and Prevention, University Tor Vergata, Roma, Italy
11Hematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece
12Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Rome, Italy
13Hematology and Clinical Immunology unit, Department of Medicine, University of Padua, Padua, Italy
14Division of Hematology, University of Turin, Torino, Italy
15Clinical and Experimental Onco-Hematology Unit, IRCCS Centro Di Riferimento Oncologico, Aviano, Italy
16Hematology Department - HCT Unit, George Papanikolaou Hospital, Thessaloniki, Greece
17Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
18Institute of Applied Biosciences, Centre for Research and Technology Hellas, Asvestohori, Greece
19Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, rome, Italy
20Immunology, Genetics and pathology, Uppsala University, Uppsala, Uppsala, Sweden

*signifies non-member of ASH