-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

636. Myelodysplastic Syndromes: Basic and Translational: Poster II

Symposia: Myelodysplastic Syndromes: Basic and Translational Program: Oral and Poster Abstracts
Type: Poster
Sunday, December 8, 2024: 6:00 PM-8:00 PM
Halls G-H (San Diego Convention Center)

Chao Shen, PhD1,2*, Tingting Tang2,3*, Kitty Wang2,3*, Zunsong Hu, PhD4, Yuan Che2,3*, Meiling Chen2,3*, Keren Zhou, PhD3*, Zhenhua Chen, PhD1,2*, Ying Qing, PhD2,3*, Wei Li, PhD2,3*, Dong Wu, PhD2,3*, Keith Leung2,3*, Lillian Sau2,3*, Zhaoxu Xu2,3*, Lucy Y. Ghoda5,6*, Guido Marcucci5,7, Xiaolan Deng, PhD2,3* and Jianjun Chen, PhD2,3,5,8

1Department of Systems Biology, City of Hope, Arcadia, CA
2Center for RNA Biology and Therapeutics, City of Hope, Duarte, CA
3Department of Systems Biology, City of Hope, Monrovia, CA
4City of Hope, Duarte, CA
5Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA
6Department of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, City of Hope Medical Center and Beckman Research Institute, Duarte, CA
7Department of Hematologic Malignancies Translational Science, Duarte, CA
8Comprehensive Cancer Center, City of Hope, Duarte, CA

Wenjun Zhang, PhD1*, Jinqin Liu1*, Gang Huang, PhD2,3, Zhijian Xiao, MD4* and Bing Li, MD1*

1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Tianjin, China
2Department of Cell Systems and Anatomy, UT Health San Antonio, San Antonio, TX
3Department of Pathology and Laboratory Medicine, UT Health San Antonio, San Antonio, TX
4State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences&Peking Union Medical College, Tianjin, China

Matteo Zampini, PhD1,2*, Gabriele Todisco, MD1,3*, Alice Chiodi, PhD4*, Chiara Chiereghin, PhD5*, Elena Saba, PhD2*, Francesco Gandolfi, PhD6*, Denise Ventura, MSc2*, Nicole Pinocchio, MSc2*, Laura Crisafulli, PhD2,7*, Matteo Brindisi2,7*, Alessia Campagna, MD3*, Alberto Termanini, PhD5*, Luca Lanino, MD2, Marta Ubezio, MD3*, Giulia Maggioni, MD3*, Antonio Russo, MD3*, Alessandro Buizza, MD1*, Elisabetta Sauta, PhD8*, Gianluca Asti, MSc3*, Saverio D'Amico, MSc3*, Veronica Vallelonga6*, Serena ML Ghisletti, PhD6,9*, Ettore Mosca, PhD4*, Francesca Ficara, PhD3,7* and Matteo Giovanni Della Porta, MD1,3*

1Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy
2IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy
3IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy
4Institute of Biomedical Technologies, National Research Council (CNR), Segrate, Italy
5Human Technopole, Milan, Italy
6Department of Experimental Oncology, European Institute of Oncology (IEO),IRCCS, Milan, Italy
7Institute for Genetic and Biomedical Research, Milan Unit, CNR, Milan, Italy
8Humanitas Research Hospital, IRCCS, Rozzano, Italy
9Dipartimento di Scienze Farmacologiche e Biomolecolari, Universita' degli studi di Milano, Milan, Italy

Junying Wu1*, Jinqin Liu1*, Lin Yang, PhD1*, Bing Li, MD1,2*, Chen Jia3*, Fuhui Li1*, Robert Peter Gale, MD4 and Zhi-jian Xiao1,5*

1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Tianjin, China
2MDS and MPN Centre, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Jinan, China
3State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Tianjin Key Laboratory of Gene Therapy for Blood Diseases, CAMS Key Laboratory of Gene Therapy for Blood Diseases, Tianjin, China
4University of California, Los Angeles, Los Angeles, CA
5MDS and MPN Centre, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Kelly Lim, MSc, BSc1,2*, Monika Kutyna, PhD3,4*, Winnie Kan, PhD5*, Angel F. Lopez, MBBS, PhD2,5*, Anna Brown, PhD6*, Agnes S. M. Yong, MD, PhD1,7, Steven W Lane, MBBS, PhD, FRCPA, FRACP8,9, Chun Yew Fong, MBBS, FRACP, FRCPA, PhD10*, Timothy P Hughes, MD, MBBS, FRACP, FRCPA4, David T Yeung, MBBS, PhD, BSc, FRACP, FRCPA3,4, David M Ross, MD, PhD, FRACP, FRCPA1,2,3,6,11*, Devendra Hiwase, MD, MBBS, PhD, FRACP, FRCPA3,4,12 and Daniel Thomas, MD, PhD, FRACP, FRCPA2,4,13

1South Australian Health and Medical Research Institute, Adelaide, Australia
2Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, Australia
3Department of Haematology, Central Adelaide Local Health Network, Adelaide, SA, Australia
4South Australian Health and Medical Research Institute, Adelaide, SA, Australia
5Cytokine Receptor Laboratory, SA Pathology, Adelaide, SA, Australia
6SA Pathology, Adelaide, SA, Australia
7Haematology Department, Royal Perth Hospital, Perth, Australia
8Cancer Program, QIMR Berghofer Medical Research Institute, Royal Brisbane and Women’s Hospital, Brisbane, QLD, Australia
9Royal Brisbane and Women’s Hospital, Brisbane, QLD, Australia
10Department of Hematology, Austin Health, Heidelberg, VIC, Australia
11College of Medicine and Public Health, Flinders Health and Medical Research Institute, Adelaide, SA, Australia
12University of Adelaide, Adelaide, SA, Australia
13Central Adelaide Local Health Network, Adelaide, SA, Australia

Terra L. Lasho, PhD1, Jenna A. Fernandez, PhD1, Jeong-Heon Lee, PhD2*, Linh D. Pham2*, Huihuang Yan, PhD3*, Christy Finke, BS1*, Abhishek A. Mangaonkar, MBBS4, Aref Al-Kali, MD1, Naseema Gangat, MBBS1, Joseph Collard5*, Claes Wahlestedt, MD PhD5*, Mrinal M. Patnaik, MD, MBBS4 and Moritz Binder, MD1

1Division of Hematology, Mayo Clinic, Rochester, MN
2Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
3Division of Computational Biology, Mayo Clinic, Rochester, MN
4Mayo Clinic, Rochester, MN
5Epigenetix Inc., Delray Beach, FL

Gabriele Todisco, MD1,2,3*, Matteo Zampini, PhD4*, Pedro Luis Moura, PhD2*, Alessandro Buizza, MD3*, Teresa Mortera-Blanco, PhD2*, Anna Tranberg, MD2*, Elena Riva, PhD4*, Maria Creignou, MD, PhD2*, Alessia Campagna, MD3*, Marta Ubezio, MD3*, Ann-Charlotte Björklund2*, Bianca Tesi, MD, PhD2*, Indira Barbosa2*, Denise Ventura, MSc4*, Francesca Ficara, PhD3,5*, Elli Papaemmanuil6, Armando Santoro, MD1,7*, Magnus Tobiasson, MD2*, Elsa Bernard, PhD8*, Matteo Giovanni Della Porta, MD1,3* and Eva Hellstrom Lindberg, MD, PhD2*

1Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy
2Center for Hematology and Regenerative Medicine (HERM), Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden
3IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy
4IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy
5Institute for Genetic and Biomedical Research, Milan Unit, CNR, Milan, Italy
6Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY
7IRCCS Humanitas Research Hospital, Rozzano, Italy
8Precision Medicine Cancer Center, Gustave Roussy, Villejuif, France

Serhan Unlu, MD1, Christopher Haddad2*, Tariq Kewan, MD3, Olisaemeka Ogbue, MBBS1, Arda Durmaz, PhD4*, Waled Bahaj, MD5, Arooj Ahmed, MD1*, Carlos Bravo-Perez, MD1,6*, Luca Guarnera, MD7, Hetty E. Carraway, MD, MBA8, Yasuo Kubota, MD, PhD1*, Carmelo Gurnari, MD, PhD1, Torsten Haferlach, MD9, Valeria Visconte, PhD10 and Jaroslaw Maciejewski11

1Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
2Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Westlake, OH
3Department of Internal Medicine, Section of Hematology, Yale University, New Haven, CT
4Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Foundation, CLEVELAND, OH
5Translational Hematology and Oncology Research, Cleveland Clinic, Cleveland, OH
6Department of Hematology and Medical Oncology, Hospital Universitario Morales Meseguer, University of Murcia, IMIB-Pascual Parrilla, CIBERER - Instituto de Salud Carlos III, Murcia, Spain
7Tor Vergata University, Rome, Italy
8Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
9MLL Munich Leukemia Laboratory, Munich, Germany
10Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Taussig Cancer Institute, Cleveland, OH
11Department of Hematology and Medical Oncology, Taussig Cancer Institute, Leukemia Program, Cleveland Clinic, Cleveland

Megha Verma1*, Matthew P Davidsohn2*, Srabani Sahu, MS3*, Kith Pradhan, PhD4*, Seyedeh Shareh Dehghani1*, Sakshi Jasra, MD5*, Ritesh Aggarwal, PhD6*, Hui Zhang7*, Michael Wysota, MD8, Divij Verma, PhD3, Amit Verma, MBBS2*, Dean Hosgood, PhD2*, Yiyu Zou2* and Aditi Shastri, MD9

1Albert Einstein College of Medicine, Bronx
2Albert Einstein College of Medicine, Bronx, NY
3Blood Cancer Institute, Department of Oncology, Albert Einstein College of Medicine, Bronx, NY
4Department of Oncology, Blood Cancer Institute, Albert Einstein College of Medicine, Bronx, NY
5Department of Hematology and Oncology, The University of Vermont Medical Center, Burlington, VT
6Montefiore Einstein Cancer Center, Blood Cancer Institute, Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY
7Albert Einstein College of Medicine, New York, NY
8Montefiore Medical Center, New York, NY
9Montefiore Einstein Comprehensive Cancer Center, Blood Cancer Institute, Department of Oncology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY

*signifies non-member of ASH