Jorge E. Cortes, MD¹, Michael W. Deininger, MD, PhD², Jane Apperley, FRCP, FRCPath, MB ³, Chrisopher Kevin Arthur, MD, FRACP, FRCPA, MBBS⁴, Charles Chuah, MBChB, MRCP(UK), FRCP(Edin)^5*, Andreas Hochhaus, MD⁶, Hugues de Lavallade, MD, PhD^7*, Jeffrey H. Lipton, MD, PhD⁸, Elza Lomaia, MD, PhD^9*, James McCloskey, MD¹⁰, Michael J. Mauro, MD¹¹, Beatriz Moiraghi, MD^12*, Carolina Pavlovsky^13*, Gianantonio Rosti, MD^14*, Philippe Rousselot, MD PhD^15*, Maria Undurraga, MD¹⁶, Lin Yang, PhD, MSc^17*, Alexander Vorog, MD^17*, Tammie Yeh, PhD^17*, L. Evan Reddick, PhD^17*, Niti Patel, PhD^17* and Hagop M. Kantarjian, MD¹⁸

¹Georgia Cancer Center at Augusta University, Augusta, GA
²Versiti Blood Research Institute, Milwaukee, WI
³Imperial College London, London, United Kingdom
⁴Royal North Shore Hospital, St. Leonards, Australia
⁵Singapore General Hospital, Duke-NUS Medical School, Singapore, Singapore
⁶Universitätsklinikum Jena, Jena, Germany
⁷King's College Hospital NHS Foundation, London, United Kingdom
⁸Princess Margaret Cancer Centre, Toronto, ON, Canada
⁹Almazov National Medical Research Centre, Saint-Petersburg, Russian Federation
¹⁰Hackensack University Medical Center, Hackensack, NJ
¹¹Memorial Sloan Kettering, New York, NY
¹²Hospital Jose Maria Ramos Mejia, Buenos Aires, Argentina
¹³Fundaleu, Buenos Aires, Argentina
¹⁴IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola (FC), Italy
¹⁵Centre Hospitalier de Versailles University de Versailles Saint-Quentin-en-Yvelines, Paris, France
¹⁶Hospital del Salvador, Santiago, Chile
¹⁷Takeda Development Center Americas, Inc., Cambridge, MA
¹⁸The University of Texas MD Anderson Cancer Center, Houston, TX

Maria Agustina Perusini¹, Camille Kockerols^2*, Daniela Žáčková, MD, PhD^3*, Franck E. Nicolini, MD, PhD⁴, Fausto Castagnetti, MD, PhD⁵, Carolina Pavlovsky^6*, Massimo Breccia^7*, Delphine Rea⁸, Carmen Fava, MD, PhD^9*, Lynn Savoie^10*, Christophe Bouvier, DM^11*, Petra Čičátková^3*, Julien Bollard, PhD^12*, Swe Linn^13*, Gopila Gupta^1*, Emilia Scalzulli, MD^14*, Tomoiku Takaku, MD, PhD^15*, Hiroshi Ureshino, MD, PhD^16*, Shinya Kimura, MD, PhD¹⁷, Sung-Eun Lee, MD, PhD^18*, Dragana Milojkovic, MD, PhD^19*, Andrew J Innes, PhD, FRCPath, MRCP^20*, Simone Claudiani, MD, PhD^21*, Valentín García Gutiérrez Sr.²², Jiri Mayer, MD²³, Peter E. Westerweel² and Dennis Dong Hwan Kim, MD, PhD¹

¹Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
²Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, Netherlands
³Dpt. of Internal Medicine Hematology and Oncology, University Hospital Brno and Masaryk University, Brno, Czech Republic
⁴Hematology Department, Centre Leon Berard, LYON Cedex 03, France
⁵Department of Medical and Surgical Sciences, Institute of Hematology “Seràgnoli”, University of Bologna, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
⁶FUNDALEU, Buenos Aires, Argentina
⁷Department of Translational and Precision Medicine, Az., Hematology-Sapienza University, Rome, Italy
⁸Hematology Department, Hôpital Saint-Louis, Paris, France
⁹Department of Clinical and Biological Sciences, University of Turin, Torino, Italy, Orbassano, To, Italy
¹⁰University of Calgary, Calgary, Canada
¹¹Fi-LMC group, Lyon, France
¹²Hematology Department, Centre Leon Berard, Lyon, France
¹³Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre/University Health Network, Toronto, Canada
¹⁴Hematology, Department of Translational and Precision Medicine, Az. Policlinico Umberto I-Sapienza University, Rome, Roma, Italy
¹⁵Saitama Medical University, Tokyo, Japan
¹⁶Department of Hematology and Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan
¹⁷Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Saga University, Saga, Japan
¹⁸Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Houston, TX
¹⁹Department of Haematology, Hammersmith Hospital, Imperial College London, London, United Kingdom
²⁰Department of Hematology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom
²¹Department of Haematology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom
²²Hematology, Hospital Universitario Ramón y Cajal, Madrid, Spain
²³Internal Medicine Hematology and Oncology, University Hospital Brno and Masaryk University, Brno, Czech Republic

Philippe Rousselot, MD PhD^1*, Jean-Christophe Ianotto, MD, PhD, HDR^2*, Philippe Quittet, MD^3*, Maya Hacini^4*, Gabrielle Roth-Guepin, MD^5*, Mathieu Meunier^6*, Frederic Maloisel^7*, Valérie Coiteux^8* and Gabriel Etienne, MD, PhD^9*

¹Centre Hospitalier de Versailles; Université Versailles Paris-Saclay, Versailles, France
²Hematology department, Centre Hospitalier Universitaire de Brest, Brest, France
³Hematology department, CHU Montpellier, Hôpital Saint Eloi, Montpellier, France
⁴Centre Hospitalier de Chambéry, Chambéry, France
⁵Department of Clinical Hematology, CHRU Nancy, Vandoeuvre Les Nancy, France
⁶Department of Hematology CHU Grenoble Alpes, Grenoble, France
⁷Strasbourg Oncologie Libérale, Sainte-Anne non-profit Clinic, Rue Philippe Thys, 67000, Strasbourg, France
⁸Centre Hospitalier Universitaire, Lille, France
⁹Hematology, Institut Bergonié, Bordeaux, France

Elias Jabbour, MD^1,2, Omer Jamy, MD³, Paul B. Koller, MD⁴, Vivian G. Oehler, MD^5*, Maria R. Baer, MD⁶, Elza Lomaia, MD, PhD^7*, Anthony M. Hunter, MD⁸, Olga Uspenskaya, MD^9*, Svetlana Samarina, MD^10*, Jorge E. Cortes, MD¹¹, Sudipto Mukherjee, MD, PhD, MPH¹², Dennis Dong Hwan Kim, MD, PhD¹³, Vera Zherebtsova, MD, PhD^14*, Vasily Shuvaev, MD^15*, Anna Turkina, MD^16*, Igor Davydkin, MD, PhD^17*, Huanshan Guo, MD^18*, Zi Chen, MD, PhD^19*, Hengbang Wang, PhD^19*, Tommy Fu, PhD^20*, Lixin Jiang, MD^20*, Zhihong Yang, PhD^20*, Cunlin Wang, MD, PhD^20*, Dajun Yang, MD, PhD^19,20,21*, Yifan Zhai, MD, PhD^18,19,20 and Hagop Kantarjian, MD¹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, University of Texas M.D. Anderson Cancer Ctr., Houston, TX
³O'Neal Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham, AL
⁴Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA
⁵Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle, WA
⁶University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD
⁷Scientific and Advisory Department of Hemotherapy of Myeloproliferative Disorders, National Research Center for Hematology, Moscow, Russian Federation
⁸Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA
⁹Leningrad Regional Clinical Hospital, St. Petersburg, Russian Federation
¹⁰Kirov Scientific Research Institute of Hematology and Blood Transfusion of the FMBA, Kirov, Russian Federation
¹¹Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA
¹²Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
¹³Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
¹⁴S.P. Botkin City Clinical Hospital, Moscow, Russian Federation
¹⁵Russian Research Institute of Hematology and Transfusiology, St. Petersburg, Russian Federation
¹⁶National Medical Research Center for Hematology, Moscow, Russian Federation
¹⁷Samara State Medical University, Samara, Russian Federation
¹⁸Guangzhou Healthquest Pharma Co., Ltd., Guangzhou, China
¹⁹Ascentage Pharma (Suzhou) Co., Ltd., Suzhou, China
²⁰Ascentage Pharma Group Inc., Rockville, MD
²¹Department of Experimental Research, State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China

Bradley Rockwell, MD¹, Nitya Dhanaraj^2*, Mark Forsberg, MD^3*, Swati Goel, MD³, David Levitz, MD³, Ridhi Gupta, MD³, Lauren Shapiro, MD³, Noah Kornblum, MD³ and Eric J. Feldman, MD^3*

¹Blood Cancer Institute, Department of Oncology, Albert Einstein College of Medicine, New York, NY
²Department of Medicine, Montefiore Medical Center, Bronx, NY
³Montefiore Einstein Comprehensive Cancer Center, Blood Cancer Institute, Department of Oncology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY

Akriti G. Jain, MD¹, Joy Nakitandwe, PhD^2*, Krishna Desai, MD^3*, Genevieve M Crane, MD, PhD^4*, David S. Bosler, MD^5*, Jill O'Brien, PA^3*, Moaath K. Mustafa Ali, MD, MPH¹, John C. Molina, MD, MEd¹, Sophia Balderman, MD^1*, Anjali S. Advani, MD¹, Hetty E. Carraway, MD, MBA¹, Aaron T. Gerds, MD, MS¹, Abhay Singh, MD, MPH¹, Matt Kalaycio, MD¹ and Sudipto Mukherjee, MD, PhD, MPH¹

¹Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
²Department of Pathology and Laboratory Medicine, Cleveland Clinic Diagnostics Institute, Cleveland, OH
³Leukemia and Myeloid Disorders, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
⁴Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland Hts, OH
⁵Department of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland

Reema Singh^1*, Sujay Rainchwar, MD, DrNB^1*, Sakshi Bhatnagar, MD, FNB^1*, Nakul Tikare, MD, DM^1*, Roy Palatty, MD, DM^1*, Tribikram Panda, MD, DM^1*, Rayaz Ahmed, MD, DM², Narendra Agrawal, MD, DM^3*, Dinesh Bhurani, MD, FRCPA^4* and Rohan Halder, MD, DM^1*

¹HEMATOLOGY, RAJIV GANDHI CANCER INSTITUTE & RESEARCH CENTRE, NEW DELHI, India
²HEMATOLOGY, MAX SUPERSPECIALITY HOSPITAL, DELHI, India
³Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India
⁴HEMATOLOGY, RAJIV GANDHI CANCER INSTITUTE & RESEARCH CENTRE, New Delhi, Madhya Pradesh, India

Valentina Giai, MD, PhD^1*, Tiziana Rosso, PhD^2*, Fausto Castagnetti, MD, PhD³, Patrizia Pregno, MD^4*, Massimiliano Bonifacio, MD^5,6*, Isabella Capodanno, MD^7*, Mario Tiribelli, MD^8*, Fabio Stagno, MD, PhD⁹, Giovanni Caocci, MD¹⁰, Antonella Gozzini, MD^11*, Luigiana Luciano, MD¹², Sara Galimberti, MD^13*, Monica Bocchia, MD^14*, Andrea Patriarca, MD^15*, Giuseppe Lanzarone, MD^16*, Bruno Martino, MD^17*, Anna Guella, MD^18*, Anna Rita Scortechini, MD^19*, Carmen Fava, MD, PhD^20,21*, Claudio Fozza, MD^22*, Simona Sica, MD, PhD^23*, Nicola Di Renzo^24*, Pellegrino Musto, MD^25*, Domenico Pastore, MD^26*, Alessandro Maggi, MD^27*, Michele Pizzuti, MD^28*, Lorella Maria Antonia Melillo, MD^29*, Angelo Michele Carella, MD^30*, Giuseppe Tarantini, MD^31*, Anna Mele, MD^32*, Elisabetta Calistri, MD^33*, Maria Rosaria Coppi, MD^26*, Fabio Saccona^34*, Emilia Scalzulli, MD^35*, Beatrice Battaglio, MD^6*, Miriam Iezza, MD^36*, Cinzia Bitetti, MD^37*, Roberto Freilone, MD^38*, Gianantonio Rosti, MD^39*, Francesco Albano, MD^40*, Fabrizio Pane⁴¹, Giorgina Specchia, MD, PhD⁴², Massimo Breccia^43*, Giovannino Ciccone, MD^2* and Giuseppe Saglio, MD⁴⁴

¹Hematology, AOU Città della Salute e della Scienza di Torino, Turin, Italy
²Clinical Epidemiology Unit and CPO Piemonte, Città della Salute e della Scienza, Turin, Italy
³Department of Medical and Surgical Sciences, Institute of Hematology “Seràgnoli”, University of Bologna, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
⁴Former Haematology Unit, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza, Torino, Italy, TORINO, ITA
⁵Department of Engineering for Innovation Medicine, Section of Innovation Biomedicine, Hematology Area, University of Verona, Verona, Italy
⁶Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy
⁷hematology, AUSL Reggio Emilia, Reggio Emilia, Italy
⁸Division of Hematology and BMT, Department of Medical Area, University of Udine, Udine, Italy
⁹Hematology Section AOU Policlinico “ G.Martino , University of Messina Italy, Messina, Italy
¹⁰University of Cagliari, Monserrato, Italy
¹¹Hematology, AOU Careggi, University of Florence, Florence, Italy
¹²Hematology Unit, Federico II University, Napoli, Italy
¹³Department of Clinical and Experimental Medicine, Hematology, University of Pisa, Pisa, Italy
¹⁴Hematology, Azienda Ospedaliera Universitaria Senese, University of Siena, Siena, Italy
¹⁵Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont and Maggiore Charity Hospital, Novara, Italy
¹⁶Department of Molecular Biotechnology and Health Sciences, Division of Hematology, University of Turin, Turin, Italy
¹⁷Division of Hematology, Azienda Ospedaliera 'Bianchi Melacrino Morelli', Reggio Calabria, Italy
¹⁸Hematology Unit, Santa Chiara Hospital, APSS Trento, Trento, Italy
¹⁹Division of Hematology, Department of Molecular and Clinical Sciences, University of Marche, Ancona, Italy, Ancona, Italy
²⁰Hematology, Mauriziano Hospital, Torino, Turin, Italy
²¹Department of Clinical and Biological Sciences, University of Turin, Turin, Italy
²²Hematology Unit – Azienda Ospedaliera Universitaria of Sassari, University of Sassari, Sassari, Italy
²³Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica Sacro Cuore, Rome, Italy
²⁴"Vito Fazzi" Hospital, Hematology and Stem Cell Transplant Unit, Lecce, Italy
²⁵Department of Precision and Regenerative Medicine and Ionian Area, "Aldo Moro" University School of Medicine, Bari, Italy; Hematology and Stem Cell Transplantation Unit, AOU Consorziale Policlinico, Bari, Italy, Bari, Italy
²⁶Hematology and Bone Marrow Transplant Unit, Brindisi, Italy, Brindisi, Italy
²⁷Division of Hematology and Bone Marrow Transplant, Ospedale S.G. Moscati, Taranto, Italy
²⁸Department of Onco-Hematology, “San Carlo” Regional Hospital, Potenza, Italy
²⁹Hematology and Stem Cell Transplantation Unit, Policlinico Riuniti Foggia, Foggia, Italy
³⁰Department of Hematology/Oncology, IRCCS, Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy, San Giovanni Rotondo (FG), Italy
³¹Haematology, Ospedale "Mons. Dimiccoli", Barletta, Italy
³²Hematology Unit, Azienda C. Panico, Tricase, Italy
³³Division of Hematology - Dipartimento Medicina Clinica 1 - Ospedale San Giacomo Apostolo, Treviso, ITA
³⁴Clinical Epidemiology Unit and CPO Piemonte, Città della Salute e della Scienza, Torino, Italy
³⁵Hematology, Department of Translational and Precision Medicine, Az. Policlinico Umberto I-Sapienza University, Rome, Roma, Italy
³⁶Istituto di Ematologia "Seràgnoli", IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
³⁷Hematology, Presidio Ospedaliero “Madonna delle Grazie”, Matera, Italy
³⁸Hematology, Department of Hematology and Oncology, Città della Salute e della Scienza di Torino, Torino, Italy
³⁹IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola (FC), Italy
⁴⁰Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), Hematology and Stem Cell Transplantation Unit, University of Bari "Aldo Moro", Bari, Italy
⁴¹Division of Hematology and SCT Unit, Federico II University, Naples, Naples, Italy
⁴²Former Full Professor of Hematology, University of Bari, Bari, Italy
⁴³Department of Translational and Precision Medicine, Az., Hematology-Sapienza University, Rome, Italy
⁴⁴Dept. of Clinical and Biological Sciences, University of Turin, Turin, Italy

Omer Karrar^1*, Elias Jabbour, MD², Jayastu Senapati, MD, DM, MBBS², Fadi G. Haddad, MD², Ghayas C. Issa, MD², Koji Sasaki, MD², Hussein A. Abbas, MD, PhD², Sara Emogene Dellasala, BS^1*, Farhad Ravandi, MBBS³, Hagop M. Kantarjian, MD² and Nicholas J. Short, MD²

¹The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX

Estela Gasparotto Emiliano^1*, Gustavo Emmanuel Alves Abrantes Santos^1*, Eliana Miranda, PhD, MEd^2*, Gislaine Oliveira Duarte, MD^3*, Guilherme Duffles, MD^3*, Carmino De Souza, MD, PhD^2* and Katia B Pagnano, MD, PhD²

¹Faculdade de Ciências Médicas, Universidade Estadual de Campinas (UNICAMP), Campinas, Brazil
²Centro de Hematologia e Hemoterapia (HEMOCENTRO), Universidade Estadual de Campinas (UNICAMP), Campinas, Brazil
³Centro de Hematologia e Hemoterapia, Universidade Estadual de Campinas (UNICAMP), Campinas, Brazil

Simona Soverini, PhD¹, Sara De Santis^2*, Cecilia Monaldi^2*, Manuela Mancini^3*, Valentina Giai, MD, PhD^4*, Marco Cerrano, MD^5*, Isabella Capodanno, MD^6*, Massimiliano Bonifacio, MD^7,8*, Elisabetta Abruzzese, MD⁹, Alessandra Iurlo, MD, PhD^10*, Fausto Castagnetti, MD, PhD¹¹, Rosaria Sancetta, MD^12*, Luciano Levato^13*, Carmen Fava, MD, PhD^14,15*, Mario Tiribelli, MD^16*, Francesco Cavazzini, MD^17*, Maria Cristina Miggiano^18*, Niccolò Bolli, MD, PhD^19*, Agostino Tafuri²⁰, Alessandro Lucchesi, MD, PhD^21*, Daniele Vallisa, MD^22*, Monia Lunghi^23*, Caterina Musolino^24*, Samantha Bruno^2*, Cristina Mosca^2*, Mauro Ciriello^25*, Giovanni Marsili^26*, Alfonso Piciocchi, MS^26*, Paola Fazi^26*, Michele Cavo, MD^27*, Jeroen J.W.M. Janssen²⁸, Peter E. Westerweel²⁹ and Fabrizio Pane²⁵

¹Department of Medical and Surgical Sciences, Institute of Hematology "L. and A. Seràgnoli", University of Bologna, Castel Maggiore, Bologna, Italy
²Department of Medical and Surgical Sciences, Institute of Hematology "L. and A. Seràgnoli", University of Bologna, Bologna, Italy
³IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia “Seràgnoli”, Bologna, Italy
⁴Hematology, AOU Città della Salute e della Scienza di Torino, Turin, Italy
⁵Hematology, Department of Hematology and Oncology, A.O.U. Città della Salute e della Scienza di Torino, Torino, Italy
⁶Hematology Unit, Azienda Unità Sanitaria Locale-IRCCS, Reggio Emilia, Italy
⁷Department of Engineering for Innovation Medicine, Section of Innovation Biomedicine, Hematology Area, University of Verona, Verona, Italy
⁸Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy
⁹Department of Hematology, S. Eugenio Hospital, Tor Vergata University, ASL Roma 2, Roma, I, Italy
¹⁰Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy
¹¹Department of Medical and Surgical Sciences, Institute of Hematology “Seràgnoli”, University of Bologna, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
¹²Hematology Unit, Dell'Angelo Hospital, Venezia-Mestre, Italy
¹³Department of Hematology-Oncology, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy
¹⁴Hematology, Mauriziano Hospital, Torino, Turin, Italy
¹⁵Department of Clinical and Biological Sciences, University of Turin, Turin, Italy
¹⁶Division of Hematology and BMT, Department of Medical Area, University of Udine, Udine, Italy
¹⁷Division of Hematology, Arcispedale Sant'Anna, University of Ferrara, Ferrara, ITA
¹⁸Hematology Department, San Bortolo Hospital, Vicenza U.O.C. di Ematologia, Vicenza, ITA
¹⁹Hematology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy
²⁰Department of Clinical and Molecular Medicine and Hematology, Sant'Andrea - University Hospital - Sapienza, University of Rome, Rome, Italy
²¹Hematology Unit, IRCCS Istituto Romagnolo per lo Studio e la Cura dei Tumori (IRST) “Dino Amadori”, Meldola, Italy
²²Hematology Unit, Ospedale Guglielmo da Saliceto, Piacenza, Italy
²³Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy
²⁴Division of Hematology, Department of Human Pathology in Adulthood and Childhood, University of Messina, Messina, Italy
²⁵Department of Clinical Medicine and Surgery, Federico II University Medical School, Naples, Naples, Italy
²⁶GIMEMA Foundation, Rome, Italy
²⁷IRCCS Azienda Ospedaliero-Universitaria di Bologna, Hematology Institute “L. e A. Seràgnoli”, Bologna, Italy
²⁸Department of Hematology, University Medical Centre Nijmegen, Nijmegen, Netherlands
²⁹Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, Netherlands

Leticia Morales Espino^1*, Ruth Stuckey, PhD^2*, Antonio Molinés Honrubia, MD^3*, Adrián Segura-Díaz, MD^1,2*, Santiago Sánchez-Sosa^1,2*, Sunil Lakhwani^4*, José David González San Miguel^5*, Nuria Hernanz Soler, MD^6*, Marina Gordillo, MD^7*, Gloria González Brito, MD^4*, Maria Tapia Torres, MD^8*, Yanira Florido^2*, Cristina Bilbao-Sieyro, PhD^1,2* and María Teresa Gómez Casares, MD, PhD^1*

¹Universidad de Las Palmas de Gran Canaria, Las Palmas, Spain
²Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas, Spain
³Complejo Hospital Universitario Insular-Materno Infantil, Las Palmas, Spain
⁴Hospital Universitario de Canarias, La Laguna, Spain
⁵Complejo Hospitalario Universitario Insular-Materno Infantil de Gran Canaria, Las Palmas, Spain
⁶Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz De Tenerife, Tenerife, ESP
⁷Hospital José Molina Orosa, Lanzarote, Spain
⁸Hospital General de La Palma, La Palma, Spain

Marisol Miranda, PhD^1*, Kellen Cristine Tjioe, PhD^1*, Muhannad Sharara, MD^2*, Maloney Mckenzie, BS^2*, Amany R. Keruakous¹, Locke Johnson Bryan, MD¹, Anand Jillella, MD¹, Vamsi K. Kota, MD¹, Avirup Guha, MBBS, MPH^1* and Jorge E. Cortes, MD¹

¹Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA
²Medical College of Georgia, Augusta University, Augusta, GA

Sachin Punatar, MD, DM^1,2*, Nishant Jindal, MD, DM^1,3*, Anant Gokarn, MD, DM^1,2*, Sumeet Mirgh, MD, DM^1,3*, Akanksha Chichra, DNB^1,2,4*, Lingaraj Nayak, MBBS, MD, DM^1,2*, Bhausaheb Bagal, MD, DM^1,2*, Vinod Hande^5*, Swapnil Chavan^5*, Komal Kumbhalwar^2*, Hari Menon, MD, DM⁶ and Navin Khattry, MD, DM^1,3*

¹Homi Bhabha National Institute, Mumbai, India
²Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Navi Mumbai, India
³Department of Medical Oncology, ACTREC, Tata Memorial Centre, Navi Mumbai, India
⁴Department of Pediatric Oncology, Tata Memorial Centre, Mumbai, India
⁵ACTREC, Tata Memorial Centre, Navi Mumbai, India
⁶St Johns National Academy of Health Sciences, Bengaluru, India

Valentina Bonuomo, MD^1*, Emanuele Koumantakis^2*, Selene Grano, MD^3*, Paola Berchialla, PhD^4*, Fausto Castagnetti, MD, PhD⁵, Bruno Martino, MD^6*, Chiara Elena, MD^7*, Monica Bocchia, MD^8*, Isabella Capodanno, MD^9*, Tamara Intermesoli^10*, Maria Cristina Miggiano^11*, Carlo Gambacorti-Passerini, MD, Prof.¹², Alessandra Iurlo, MD, PhD^13*, Francesca Lunghi^14*, Luigiana Luciano, MD¹⁵, Elisabetta Abruzzese, MD¹⁶, Angelo Michele Carella, MD^17*, Massimo Breccia^18*, Felicetto Ferrara, MD^19*, Sabrina Leonetti Crescenzi, MD^20*, Barbara Scappini^21*, Marco De Gobbi, MD, PhD^22*, Federica Sorà^23*, Davide Rapezzi, MD^24*, Debora Luzi, MD^25*, Sara Galimberti, MD^26*, Monica Crugnola, MD^27*, Anna Rita Scortechini, MD^28*, Alessandro Maggi^29*, Massimiliano Bonifacio, MD^30*, Mario Annunziata, MD^31*, Giovanni Caocci, MD³², Germana Beltrami, MD^33*, Francesco Cavazzini, MD^34*, Giuseppe Pietrantuono, MD^35*, Leonardo Campiotti^36*, Fabio Stagno, MD, PhD³⁷, Caterina Musolino^38*, Daniela Cilloni, MD^39*, Giuseppe Saglio, MD⁴⁰ and Carmen Fava, MD, PhD^41*

¹Department of Clinical and Biological Sciences, University of Turin, Rivoli, Italy
²Universita' Degli Studi Di Torino UNITO, Torino, ITA
³Department of Molecular Biotechologies and Health Sciences, University of Torino, Turin, ITA
⁴Department of Clinical and Biological Sciences, University of Torino, Orbassano, Italy
⁵Department of Medical and Surgical Sciences, Institute of Hematology “Seràgnoli”, University of Bologna, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
⁶Division of Hematology, Azienda Ospedaliera 'Bianchi Melacrino Morelli', Reggio Calabria, Italy
⁷U.O.C Ematologia 1, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
⁸Hematology Unit, Azienda Ospedaliera Universitaria Senese, University of Siena, Siena, Siena, Italy
⁹hematology, AUSL Reggio Emilia, Reggio Emilia, Italy
¹⁰Hematology and Bone Marrow Transplant Unit, Azienda Socio-Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy
¹¹Hematology Department, San Bortolo Hospital, Vicenza U.O.C. di Ematologia, Vicenza, ITA
¹²Department of Medicine and Surgery, University Milano-Bicocca, Monza, Italy
¹³Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy
¹⁴San Raffaele Institute Milano Italy, Milano, ITA
¹⁵Hematology Unit, Federico II University, Napoli, Italy
¹⁶Department of Hematology, S. Eugenio Hospital, Tor Vergata University, ASL Roma 2, Roma, I, Italy
¹⁷Department of Hematology/Oncology, IRCCS, Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy, San Giovanni Rotondo (FG), Italy
¹⁸Department of Translational and Precision Medicine, Az., Hematology-Sapienza University, Rome, Italy
¹⁹Division of Hematology, AORN Cardarelli, Naples, Napoli, Italy
²⁰Division of Hematology, Azienda Ospedaliera San Giovanni Addolorata, Roma, Italy
²¹Hematology Unit, Hematology Unit, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
²²Department of Clinical and Biological Sciences, Department of Clinical and Biological Sciences, University of Turin, Orbassano, ITA
²³Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy
²⁴Department of Hematology, S. Croce e Carle Hospital, Cuneo, Italy
²⁵Onco-Hematology Department, AO Santa Maria, Terni, Terni, Italy
²⁶Department of Clinical and Experimental Medicine, Hematology, University of Pisa, Pisa, Italy
²⁷Hematology Unit, University of Parma, Parma, Italy
²⁸Division of Hematology, Department of Molecular and Clinical Sciences, University of Marche, Ancona, Italy, Ancona, Italy
²⁹Division of Hematology and Bone Marrow Transplant, Ospedale S.G. Moscati, Taranto, Italy
³⁰Department of Engineering for Innovation Medicine, Section of Innovation Biomedicine, Hematology Area, University of Verona, Verona, Italy
³¹Hematology, San Giuseppe Moscati Hospital, Aversa, Italy
³²University of Cagliari, Monserrato, Italy
³³U.O. Ematologia e terapie cellulari, IRCCS Azienda Ospedaliera Universitaria San Martino, Genova, Italy
³⁴Division of Hematology, Arcispedale Sant'Anna, University of Ferrara, Ferrara, ITA
³⁵Hematology and Stem Cell Transplantation Unit, IRCCS Centro Oncologico della Basilicata, Rionero in Vulture, Italy
³⁶Department of Medicine and Surgery, University of Insubria, Varese, ITA
³⁷Hematology Section, Biomedical Sciences, Trecastagni, Catania, Italy
³⁸Division of Hematology, Department of Human Pathology in Adulthood and Childhood, University of Messina, Messina, Italy
³⁹Department of Clinical and Biological Sciences, University of Turin, Orbassano, ITA
⁴⁰Dept. of Clinical and Biological Sciences, University of Turin, Turin, Italy
⁴¹Department of Clinical and Biological Sciences, University of Turin, Turin, Italy

Isidora Staikdou, MBBS^1,2*, Simone Claudiani, MD, PhD^1,2*, Fiona R Fernando, MD, MRCP, FRCPath^1,2*, David Slade^1*, Afzal Khan^1*, Chloe Hayden, BSc^3*, Eduardo Olavarria, MD, PhD^1*, Jiri Pavlu, MD, FRCPath, MRCP^1,2, Renuka Palani, MD^1*, Dragana Milojkovic, MD, PhD^2,4*, Jane Apperley, FRCP, FRCPath, MB ^1,2 and Andrew J Innes, PhD, FRCPath, MRCP^1,2*

¹Department of Haematology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom
²Centre for Haematology, Department of Immunology and Inflammation, Faculty of Medicine, Imperial College London, London, United Kingdom
³North West London Pathology, Imperial College Healthcare NHS Trust, London, United Kingdom
⁴Department of Haematology, Hammersmith Hospital, Imperial College London, London, United Kingdom