Alexandre Guy, MD, PhD^1,2*, Olivier Mansier, PharmD, PhD^1,3*, Alexandre Catherineau^4*, Geoffrey Garcia, PharmD^1*, Sylvie Labrouche-Colomer, PharmD, PhD^1,3*, Valentin Landrieu, PharmD^3*, Marie-Lise Bats, PharmD, PhD^1,5*, Francoise Boyer, MD^6*, Jean-Christophe Ianotto, MD, PhD^7*, Lydia Roy, MD^8*, Suzanne Tavitian, MD^9*, Borhane Slama, MD^10*, Stephane Girault, MD^11*, Gabriel Etienne, MD, PhD^12*, Anne Parry, MD^13*, Arnaud Saint-Lezer, MD^14*, Guillaume Denis, MD^15*, Clemence Mediavilla, MD^16*, Jean-Francois Viallard, MD PhD^17*, Laurence Legros, MD, PhD^18*, Dana Ranta, MD^19*, Mathieu Wemeau, MD^20*, Franck E. Nicolini, MD, PhD²¹, Francois Lifermann, MD^22*, Nathalie Cambier, MD^23*, Luc Darnige, MD^24*, Francois Girodon, MD, PhD^25*, Juliette Soret-Dulphy^26*, Emilie Cayssials, MD, PhD^27*, Fabienne Vacheret, MD^28*, Léa Sureau^29*, Damien Luque-Paz, PharmD, PhD^30*, Valérie Ugo, MD, PhD^29*, Jean-Jacques Kiladjian, MD, PhD³¹, Rodolphe Thiébaut, MD, PhD^4* and Chloe James, MD, PhD^1,3*

¹Biology of Cardiovascular Diseases, University of Bordeaux, INSERM, UMR1034, Pessac, France
²Bordeaux University Hospital, PESSAC, France
³Laboratory of Hematology, Bordeaux University Hospital, Pessac, France
⁴Department of Medical Information, Bordeaux University Hospital, Bordeaux, France
⁵Laboratory of Biochemistry, Bordeaux University Hospital, Bordeaux, France
⁶Department of Hematology, Angers University Hospital, Angers, France
⁷Department of Hematology, Brest University Hospital, Brest, France
⁸Hematology Department, Henri Mondor University Hospital, UPEC, IMRB, Assistance Publique Hopitaux de Paris, Créteil, France
⁹Department of Hematology, Toulouse University Cancer Institute Oncopole, Toulouse University Hospital, Toulouse, France
¹⁰Department of Hematology, Avignon Hospital Center, Avignon, France
¹¹Department of Hematology, Limoges University Hospital, Limoges, France
¹²Hematology, Institut Bergonié, Bordeaux, France
¹³Department of Hematology, Annecy Genevois Hospital Center, Pringy, France
¹⁴Department of Hematology, Mont-De-Marsan Hospital Center, Mont-De-Marsan, France
¹⁵Department of Hematology, Rochefort Hospital, Rochefort, France
¹⁶Hematology Department, CHU de Bordeaux, Bordeaux, France
¹⁷Department of Internal Medicine, Bordeaux University Hospital, Pessac, France
¹⁸Service d’Hématologie-Clinique Ambulatoire (SHCA), APHP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France
¹⁹Department of Hematology, Nancy University Hospital, Vandoeuvre Les Nancy, France
²⁰Department of Hematology, Roubaix Hospital, Roubaix, France
²¹Hematology Department, Centre Leon Berard, LYON Cedex 03, France
²²Department of Internal Medicine, Dax Hospital, Dax, France
²³Hematology department, Hospital of Valenciennes, Valenciennes, FRA
²⁴Laboratory of Hematology, APHP Georges-Pompidou European Hospital, Paris, France
²⁵Laboratory of Biological Hematology, University Hospital of Dijon, Dijon, France
²⁶Clinical Investigation Center, Saint-Louis Hospital, Paris, France
²⁷Hematology department & CIC, CHU Poitiers & INSERM CIC 1402, Poitiers, France
²⁸Department of Hematology, Perpignan Hospital Center, Perpignan, FRA
²⁹Laboratory of Hematology, Angers University Hospital, Angers, France
³⁰Université Angers, Nantes Université, CHU Angers, INSERM, CNRS, CRI2NA, Angers, France
³¹Clinical Investigation Center, Hôpital Saint-Louis, Université de Paris, Paris, France

Lucas Wadley, BS^1*, Hew Yeng Lai, PhD^2*, Eshika Arora^1*, Helen Huang^3*, Jianhong C Heidmann, BS^4*, Dennis Jing, BS^5*, Lauren Chen^1* and Angela G. Fleischman, MD, PhD⁴

¹University of California, Irvine, Irvine, CA
²UCI, Irvine, CA
³Division of Hematology/Oncology, University of California, Irvine, IRVINE, CA
⁴Division of Hematology/Oncology, University of California, Irvine, Irvine, CA
⁵University of California, Irvine, Irvine

Yuka Sato^1*, Koki Ueda, MD, PhD¹, Keiji Minakawa, MS^1*, Saori Miura, PhD^1,2* and Kazuhiko Ikeda, MD, PhD¹

¹Department of Blood Transfusion and Transplantation Immunology, School of Medicine, Fukushima Medical University, Fukushima, Japan
²Department of Clinical Laboratory Sciences, School of Health Science, Fukushima Medical University, Fukushima, Japan

Abdulraheem Yacoub, MD^1*, Ellen K. Ritchie, MD², Naveen Pemmaraju, MD³, Richard Zuniga^4*, Erin L. Crowgey, PhD^5*, Cynthia Timmers, PhD^5*, Patricia Feldman^5*, J.E. Hamer-Maansson, MSPH^5*, Tricia Kalafut^5*, Evan M. Braunstein, MD, PhD^5* and John O. Mascarenhas, MD⁶

¹University of Kansas Medical Center, Westwood, KS
²Weill Cornell Medicine and The New York Presbyterian Hospital in New York City, New York, NY
³The University of Texas MD Anderson Cancer Center, Houston, TX
⁴New York Cancer & Blood Specialists, New York, NY
⁵Incyte Corporation, Wilmington, DE
⁶Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY

Matteo Brindisi^1,2*, Laura Crisafulli, PhD^1,2*, Matteo Zampini, PhD^1*, Mirko Liturri, MSc^1*, Elena Riva, PhD^1*, Elena Saba, PhD^1*, Alessia Campagna, MD^1*, Luca Lanino, MD^1,3, Marta Ubezio, MD^1*, Gabriele Todisco, MD^3*, Giulia Maggioni, MD^1*, Antonio Russo, MD^1*, Nicla Manes, MSc^1*, Denise Ventura, MSc^1*, Nicole Pinocchio, MSc^1*, Dario Strina^1,2*, Lucia Susani^1,2*, Matteo Giovanni Della Porta, MD^1,3* and Francesca Ficara, PhD^1,2*

¹IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy
²Institute for Genetic and Biomedical Research, Milan Unit, CNR, Milan, Italy
³Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy

Chen Jia^1*, Ting Sun^1*, Renchi Yang^1*, Rongfeng Fu, MD^1* and Lei Zhang^1,2

¹Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
²Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, China, Tianjin, China

Hosuk Ryou^1*, Laura Harding^2*, Jens Rittscher^1* and Daniel Royston, DPhil, FRCPath, MBBChir³

¹Institute of Biomedical Engineering, University of Oxford, Oxford, United Kingdom
²Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
³Nuffield Division of Clinical Laboratory Sciences, University of Oxford, Oxford, United Kingdom

Saori Miura, PhD^1,2*, Koki Ueda, MD, PhD², Tomofumi Misaka, MD, PhD^3*, Masato Matsuda, PhD^1*, Keiji Minakawa, MS^2*, Yuka Sato^2*, Yasuchika Takeishi, MD, PhD^3* and Kazuhiko Ikeda, MD, PhD²

¹Department of Clinical Laboratory Sciences, School of Health Science, Fukushima Medical University, Fukushima, Japan
²Department of Blood Transfusion and Transplantation Immunology, School of Medicine, Fukushima Medical University, Fukushima, Japan
³Department of Cardiovascular Medicine, School of Medicine, Fukushima Medical University, Fukushima, Japan

Xiaoshuai Zhang^1*, Zongru Li, MD^2*, Lu Yu^3*, Mei Bao^4* and Qian Jiang, MD^2,5,6

¹Peking University Peoples Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing, China
²Peking University People’s Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
³National Clinical Research Center for Hematologic Disease, Peking University People’s Hospital, Peking University Institute of Hematology, Beijing, China
⁴Peking University People's Hospital, Beijing, China
⁵National Clinical Research Center for Hematologic Disease, Peking University People’s Hospital, Peking University Institute of Hematology, Beijing, Beijing, China
⁶Peking University People’s Hospital,Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing, China

Warren C. Fiskus, BSc, PhD¹, Lucia Masarova, MD², Christopher Peter Mill, PhD, BA³, Christine Birdwell, PhD³, Kaberi Das, PhD^1*, John A. Davis^3*, Hanxi Hou^4*, Kevin Philip^4*, Alicia Matthews^4*, Taghi Manshouri, PhD^2*, Surbhi Sharma, PhD⁵, Tapan M. Kadia, MD², Courtney D. DiNardo, MD, MSc⁶, Prithviraj Bose, MD⁴, Naveen Pemmaraju, MD⁷, Sanam Loghavi, MD⁸, Marie Törngren, PhD^9* and Kapil N. Bhalla, MD¹

¹UT MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³MD Anderson Cancer Center, Houston, TX
⁴The University of Texas MD Anderson Cancer Center, Houston, TX
⁵The UT MD Anderson Cancer Center, Houston, TX
⁶Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
⁷Department of Leukemia, The University of Texas MD Anderson Cancer Center, Bellaire, TX
⁸Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
⁹Active Biotech, Lund, Sweden

Hanqian L Carlson^1*, Samantha Tauchmann, PhD^2*, Thai Nguyen, MS^1*, Sarah A Carratt, PhD, DABT^3*, Tao Liu^4*, Theodore P Braun, MD, PhD^1,5,6,7 and Julia E Maxson, PhD^1,5,7

¹Oregon Health & Science University, Portland, OR
²Oregon Health and Scienc University, Portland,, OR
³Oregon Health and Science University, Portland, OR
⁴Biological Sciences Division, Pacific Northwest National Laboratories, Richland,, WA
⁵Knight Cancer Institute, Oregon Health & Science University, Portland, OR
⁶Division of Hematology & Medical Oncology, Oregon Health & Science University, Portland, OR
⁷Division of Oncologic Sciences, Oregon Health & Science University, Portland, OR

Graeme Greenfield, BA, MRCP, BMBS^1*, Yu Sheng^1*, Lisa J Crawford, BSc, PhD^2*, Yaser Atlasi, PhD^1*, Dan Longley, PhD^1*, Ken I Mills, PhD, FRCPath² and Mary Frances McMullin, MD, FRCPath, FRCP³

¹Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, United Kingdom
²Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, NI, United Kingdom
³BHSCT, Belfast, United Kingdom

Stephen T. Oh, MD, PhD^1*, Jeffrey I. Zwicker, MD^2,3, Kamal Patel, MD^4*, Erin L. Crowgey, PhD^5*, Cynthia Timmers, PhD^5*, Patricia Feldman^5*, Justine Carl^5*, J.E. Hamer-Maansson, MSPH^5*, Valkal Bhatt, PharmD^5*, Evan M. Braunstein, MD, PhD^5* and Michael R. Grunwald, MD⁶

¹Washington University School of Medicine, St. Louis, MO
²Weill Cornell Medical College, New York, NY
³Memorial Sloan Kettering Cancer Center, New York, NY
⁴CARTI Cancer Center, Little Rock, AR
⁵Incyte Corporation, Wilmington, DE
⁶Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC

Charlotte K Brierley, bmbch¹, Charlotte Gaskell, BSc MSc^2*, Claire Harrison³, Christina Yap, PhD^2,4*, Aimee Jackson, BSc MSc^2*, Jennifer Byrne, FRCP FRCPath PhD^5*, Angela Hamblin, MD, PhD^6*, Sally-Ann Clark, PhD, BSc^1*, Jennifer O Sullivan, MD PhD^1,7*, Alba Rodriguez-Meira, PhD^1,8,9*, Lauren Murphy, BSc^1*, Fiona Jane Clarke, MD^10*, Srinivasan Narayanan, FRCP, FRCPath^11*, David T. Bowen, MD, PhD^12*, Emma Gudgin, MBBS, MRCP, FRCPath, PhD^13*, Dragana Milojkovic, MBBS, MRCP, FRCPath, PhD^14*, Rebecca Collings^2*, Bethan Psaila, MD, PhD¹⁵, Steve Knapper, MRCP, FRCPath, DM^16*, Mark W. Drummond, PhD, FRCPath^17* and Adam J Mead, PhD, MRCP, FRCPath¹⁸

¹Medical Research Council (MRC) Weatherall Institute of Molecular Medicine (WIMM) and NIHR Biomedical Research Centre, University of Oxford, Oxford, United Kingdom
²Cancer Research UK Trials Unit, University of Birmingham, Birmingham, United Kingdom
³Guy's and St Thomas' NHS Foundation Trust, London, ENG, United Kingdom
⁴The Institute of Cancer Research, Sutton, ENG, GBR
⁵Nottingham University Hospitals NHS Trust, Nottingham, GBR
⁶Department of Haematology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
⁷Dept of Haematology, Guys and St Thomas’ NHS Foundation Trust, London, United Kingdom
⁸Broad Institute of MIT and Harvard, Cambridge, MA
⁹Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA
¹⁰University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom
¹¹University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom
¹²St. James's Institute of Oncology, Leeds Teaching Hospitals, Leeds, GBR
¹³Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom
¹⁴Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, GBR
¹⁵Medical Research Council (MRC) Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, ENG, United Kingdom
¹⁶School of Medicine, Cardiff University, Cardiff, United Kingdom
¹⁷Dept of Haematology, Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom
¹⁸Medical Research Council (MRC) Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, United Kingdom

Florian Siegerist^1,2*, Tina M Schnoeder, PhD^3*, Ashok Kumar Jayavelu, PhD.^4,5*, Florian Perner, MD⁶, Philipp Jost^7*, Elke Hammer^8*, Uwe Völker^8*, Karen Lopez-Cayuqueo^9*, Kai Schmidt-Ott^9*, Maike Büttner-Herold, MD^10*, Nicole Endlich^2,11* and Florian H. Heidel, MD^12,13

¹Department of Pediatrics, University Medicine Greifswald, Greifswald, Germany
²Institute of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany
³Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School (MHH), Hannover, Germany
⁴German Cancer Research Center (DKFZ), Heidelberg, Germany
⁵Max-Planck-Institute of Biochemistry, Munich, Germany
⁶Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
⁷Division of Clinical Oncology, Internal Medicine, Medical University of Graz, Graz, Austria
⁸Institute of Functional Genomics, University Medicine Greifswald, Greifswald, Germany
⁹Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany
¹⁰Department of Nephropathology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
¹¹NIPOKA GmbH, Greifswald, Germany
¹²Leibniz Institute on Aging, Fritz-Lipmann-Institute, Jena, Germany
¹³Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany

John O. Mascarenhas, MD¹, Uma Borate, MD², Prithviraj Bose, MD³, John C. Byrd, MD⁴, Jacqueline S. Garcia, MD⁵, Michael R. Grunwald, MD⁶, Gabriela S. Hobbs, MD⁷, Ronald Hoffman, MD⁸, Andrew T. Kuykendall, MD⁹, Ruben A. Mesa, MD¹⁰, Stephen Oh, MD, PhD¹¹, Raajit Rampal, MD, PhD¹², Abdulraheem Yacoub, MD¹³ and David P. Steensma, MD¹⁴

¹Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
²The Ohio State University, Columbus, OH
³The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Department of Internal Medicine, University of Cincinnati, Cincinnati, OH
⁵Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
⁶Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC
⁷Division of Hematology/Oncology, Massachusetts General Hospital, Boston, MA
⁸The Tisch Cancer Institute, Division of Hematology & Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
⁹Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
¹⁰Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, NC
¹¹Washington University School of Medicine, Saint Louis, MO
¹²Memorial Sloan Kettering Cancer Center, New York, NY
¹³University of Kansas Cancer Center, Leawood, KS
¹⁴Ajax Therapeutics, Cambridge, MA