Stefania Leone^1,2*, Francesco Grimaldi, MD^3*, Mara Memoli^4*, Flavia Carriero^5*, Giulia Scalia^6*, Annamaria Vincenzi^7*, Giuseppe Cerciello^8*, Fabrizio Pane⁹, Alessandra Picardi, MD^10*, Giuseppe Terrazzano^5*, Giuseppina Ruggiero^11* and Valentina Rubino^11*

¹University federico II of Naples, Naples, Italy
²AORN Cardarelli, Naples, Italy
³Department of Clinical Medicine and Surgery, Hematology Unit, University of Naples Federico II, Napoli, Italy
⁴Department of Medicine and Surgery, Hematology and Hematopoietic Stem Cell Transplant Center, University of Naples Federico II, Naples, Naples, Italy
⁵Department of Sciences, University of Basilicata, Potenza, Italy
⁶Centre for Advanced Biotechnology (CEINGE), Naples, Italy
⁷Aou-Federico II, Naples, Naples, ITA
⁸Hematology, "San Pio" Hospital of Benevento, Naples, ITA
⁹Division of Hematology and SCT Unit, Federico II University, Naples, Naples, Italy
¹⁰Stem Cell Transplant Program AORN Cardarelli, Naples and Biomedicine and Prevencion Department of Tor Vergata University, Rome, Naples / Rome, Italy
¹¹Department of Translational Medicine, University of Naples Federico II, Naples, Italy

Xuan Zhang, PhD^1*, Guangyuan Li^2*, Anna Oliverio^3*, Jennifer VanOudenhove, PhD⁴, Amy E. DeZern, MD, MHS^5,6, Gabriel Ghiaur, MD, PhD⁷, Stephanie Halene, MD⁸, H. Leighton Grimes, PhD^9,10 and Nathan Salomonis, PhD^11*

¹Division of Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
²Perlmutter Cancer Center, New York University, New York City, NY
³Division of Biomedical Informatics, Cincinnati Children's Hosptial, Cincinnati, OH
⁴Department of Internal Medicine, Section of Hematology, Yale University, New Haven, CT
⁵Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD
⁶The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD
⁷Division of Hematologic Malignancies, Department of Medical Oncology, Sidney Kimmel Comprehensive Cancer Center, John's Hopkins Hospital, Baltimore, MD
⁸Yale Univ. School of Medicine, New Haven, CT
⁹Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
¹⁰Division of Immunobiology, Cincinnati Children's Hospital, Cincinnati, OH
¹¹Division of Biomedical Informatics, Cincinnati Children's Hospital, Cincinnati, OH

Valerie Awad, MS^1* and Teresa V. Bowman, PhD²

¹Developmental and Molecular Biology, Albert Einstein College of Medicine, New York
²Department of Oncology, Department of Molecular and Developmental Biology, Albert Einstein College of Medicine, New York, NY

Rahul Roy, MSc^1*, Manoj Pillai, MD¹ and Prajwal Boddu, MD²

¹Yale University, New Haven, CT
²Yale University, East Lyme, CT

Rahul Roy, MSc^1*, Abhishek Gupta^1*, Manoj Pillai, MD¹ and Prajwal Boddu, MD²

¹Yale University, New Haven, CT
²Yale University, East Lyme, CT

Pawan Bhat, BSc¹, Joseph C. Van Amburg, MS^2*, Thomas J. Gracie, MD^3*, Justin A Cartailler, BA^4*, Chad R Potts, BS^4*, Alexander G. Bick, MD, PhD^5*, Robert Welner, PhD⁶ and Brent Ferrell Jr., MD^4,7

¹School of Medicine, Program in Cancer Biology, Vanderbilt University, Nashville, TN
²School of Medicine, Human Genetics Program, Vanderbilt University, Nashville, TN
³Internal Medicine Residency, Vanderbilt University Medical Center, Nashville, TN
⁴Department of Medicine, Vanderbilt University Medical Center, Nashville, TN
⁵Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN
⁶Division of Hematology and Oncology, Department of Medicine, UAB Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL
⁷Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN

Amro Baassiri, MD, PhD^1*, Jamie Maziarz^2*, Holly Nicole Blackburn, MD^3*, Hannah Maul-Newby, PhD^2*, Jennifer VanOudenhove, PhD^1,4, Xuan Zhang, PhD^5*, Martin Matthews, MS^1*, Sambuddha Paul, MS^2*, Wei Liu^2*, Esen Sefik, PhD^6*, Nathan Salomonis, PhD^7*, H. Leighton Grimes, PhD⁸, Richard Flavell, PhD, FRS^3* and Stephanie Halene, MD⁹

¹Department of Internal Medicine, Section of Hematology, Yale University, New Haven, CT
²yale university, new haven
³Yale University, New Haven, CT
⁴Yale Cancer Center, Section of Hematology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT
⁵Division of Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
⁶Yale University School of Medicine, New Haven, CT
⁷Division of Biomedical Informatics, Cincinnati Children's Hospital, Cincinnati, OH
⁸Division of Immunobiology, Cincinnati Children's Hospital, Cincinnati, OH
⁹Yale Univ. School of Medicine, New Haven, CT

Jeremy Connors^1*, Linda Zhang^2*, Hidetaka Uryu, MD, PhD^3*, Koji Sasaki, MD⁴, Jennifer Padilla^2*, Zongrui Li^5*, Ken Furudate, DMD, PhD^4*, Tomoyuki Tanaka^1*, Courtney D. DiNardo, MD, MSc⁶, Nicholas J. Short, MD⁴, Naval Daver, MD⁷, Gautham Borthakur^8*, Farhad Ravandi, MBBS⁹, Tapan M. Kadia, MD⁴, Hagop M. Kantarjian, MD⁴, Elias Jabbour, MD¹⁰, Simona Colla, PhD¹¹, Branko Cuglievan, MD¹², Andrew Futreal, PhD^13*, Adam S. Sperling, MD, PhD¹⁴, Guillermo Garcia-Manero, MD⁴, Margaret Goodell, PhD¹⁵ and Koichi Takahashi, MD, PhD¹⁶

¹The University of Texas MD Anderson Cancer Center, Houston
²Baylor College of Medicine, Houston
³Leukemia, The UNIVERSITY of TEXAS, M.D. Anderson, Houston, TX
⁴Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Leukemia, MD Anderson Cancer Center, Houston, TX
⁶Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
⁷MD Anderson Cancer Center, Houston, TX
⁸The University of Texas MD Anderson Cancer Center, Houston, TX
⁹Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX
¹⁰Department of Leukemia, University of Texas M.D. Anderson Cancer Ctr., Houston, TX
¹¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston
¹²Division of Pediatrics, MD Anderson Cancer Center, Houston, TX
¹³Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁴Dana-Farber Cancer Institute, Boston, MA
¹⁵Department of Molecular Cell Biology, Baylor College of Medicine, Houston, TX
¹⁶Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX

Maha M Kamel, MBioChem, BScPharm^1,2*, Nirmal Robinson, M.Pharm, PhD^3*, Monika Kutyna, PhD^4,5*, Kelly Lim, MSc, BSc^1,2*, Chloe Thompson-Peach, PhD^1,2*, Steven W Lane, MBBS, PhD, FRCPA, FRACP⁶, David T Yeung, MBBS, PhD, BSc, FRACP, FRCPA⁵, Agnes S. M. Yong, MD, PhD^2,7, David M Ross, MD, PhD, FRACP, FRCPA^2,8*, Devendra Hiwase, MD, MBBS, PhD, FRACP, FRCPA^5,9 and Daniel Thomas, MD, PhD, FRACP, FRCPA^5,8,10

¹Adelaide Medical School, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, Australia
²South Australian Health and Medical Research Institute, Adelaide, Australia
³Centre for Cancer Biology, University of South Australia, Adelaide, Australia
⁴Adelaide Medical School, The University of Adelaide, Adelaide, SA, Australia
⁵South Australian Health and Medical Research Institute, Adelaide, SA, Australia
⁶Cancer Program, QIMR Berghofer Medical Research Institute, Royal Brisbane and Women’s Hospital, Brisbane, QLD, Australia
⁷Haematology Department, Royal Perth Hospital, Perth, Australia
⁸Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, Australia
⁹Department of Haematology, Central Adelaide Local Health Network, Adelaide, SA, Australia
¹⁰Central Adelaide Local Health Network, Adelaide, SA, Australia