Daniel Isaac, DO, MSc^1*, Roshni Kulkarni, MD², Binh Le, PhD^3*, Marilyn Manco-Johnson, MD⁴, Patricia Tobase, PT, DPT, OCS^5* and Mike Soucie, PhD^6,7*

¹College of Human Medicine, Michigan State University, Kalamazoo, MI
²Centers for Bleeding and Clotting Disorders, Department of Pediatrics, Michigan State University, East Lansing, MI
³Division of Blood Disorders, Centers for Disease Control and Prevention, Atlanta, GA
⁴Hemophilia & Thrombosis Center, University of Colorado Anschutz Medical Campus, Aurora, CO
⁵Hemophilia Treatment Center, University of California, San Francisco, CA
⁶Peers & Partners, Inc; Division of Blood Disorders, Centers For Disease Control and Prevention, Atlanta, GA
⁷CDC, Peers & Partners, Inc, Atlanta, GA

Samuel Wilson, MD^1*, Wei Pan, PhD^2*, Olu Jegede, MD, MHA^3*, Sarah Leonard, MD^4*, Payal Desai, MD⁵, Daniel Hatch, Ph.D^6*, Camila Reyes^7*, Paula Jean Tanabe, PhD, RN, FAEN, FAAN⁸, Tyra Girdwood^6*, Shelby Weeks, MHS^9* and Mariam Kayle, PhD⁶

¹Division of Hematology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC
²School of Nursing and School of Medicine, Duke University, Durham, NC
³Cone Health, Greensboro, NC
⁴Brody School of Medicine, East Carolina University Health, Greenville, NC
⁵Levine Cancer Institute, Department of Hematology, Atrium Health, Charlotte, NC
⁶School of Nursing, Duke University, Durham, NC
⁷School of Medicine, Duke University, Durham, NC
⁸Duke University, Durham, NC
⁹Division of Public Health, North Carolina Department of Health and Human Services, Raleigh, NC

Fathia Oladipupo^1*, Joseph R Stanek, MS^2*, Joseph Walden^1*, Jennifer Young^3*, Melissa J. Rose, DO⁴, Anthony Villella, MD^3* and Susan Elizabeth Creary, MD, MSc¹

¹Nationwide Children's Hospital Research Institute, Columbus, OH
²Division of Biostatistics, Nationwide Children's Hospital, Columbus, OH
³Nationwide Children's Hospital, Columbus, OH
⁴Nationwide Children’s Hospital, Columbus, OH

Jacob Cogan, MD, Julia D Meyer, BS^* and Ziou Jiang, MS^*

University of Minnesota, Minneapolis, MN

Emma P Deloughery, MD

Oregon Health & Science University, Portland, OR

Jeffrey G Edwards, MD, MPH¹, Daniel Humphrey^2*, Martina Mueller, PhD^2,3*, Shannon Phillips, PhD, RN^2*, Morohuntodun O. Oni^4*, Julie Kanter, MD⁵, Kira Bona, MD, MPH⁶ and Natasha Archer, MD⁷

¹Boston Children's Hospital, Brookline, MA
²College of Nursing, Medical University of South Carolina, Charleston, SC
³Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC
⁴Dana-Farber / Boston Children’s Cancer and Blood Disorders Center, Brookline, MA
⁵Division of Hematology and Oncology, University of Alabama At Birmingham, Birmingham, AL
⁶Division of Pediatric Hematology/Oncology, Boston Children’s Hospital, Boston, MA
⁷Dana-Farber/Boston Children's Cancer and Blood Disorder Ctr., Boston, MA

Alexa Loncharich, MD¹, Suhong Lou, MS^2*, Brian F. Gage, MD, MS^3*, Amber Afzal, MD, MSc⁴, Martin William Schoen, MD, MPH^5* and Kristen M. Sanfilippo, MD^5,6

¹Washington University School of Medicine in St. Louis, St Louis, MO
²St. Louis Veterans Affairs Medical Center, Research Service, St Louis, MO
³Washington Univeristy School of Medicine in St. Louis, Saint Louis, MO
⁴Washington University in St Louis, Saint Louis, MO
⁵St. Louis Veterans Affairs Medical Center Research Service, St. Louis, MO
⁶Department of Medicine, Washington University School of Medicine, St. Louis, MO

Sara Khan, DO¹, Faraz Eshaghi, DO^2*, Aruba Sohail^3*, Kainat Khan^4*, Taha Huda, MD^2*, Evan Lindbergh, DO^5* and Kapisthalam S. Kumar, MD⁶

¹Internal Medicine, HCA Healthcare/USF Morsani College of Medicine GME: Bayonet Point, Longwood, FL
²HCA Healthcare/USF Morsani College of Medicine GME Bayonet Point Hospital, hudson, FL
³Dow University of Health Sciences, Karachi, Pakistan
⁴Edward Via College of Osteopathic Medicine, Auburn, AL
⁵HCA Florida Bayonet Point, hudson, FL
⁶Florida Cancer Specialists, Trinity, FL

Warren B Fingrut, MD^1,2, Eric Davis, MPH, CHTC^2,3,4*, Anne Archer^3,4*, Samantha Brown^5*, Sean M. Devlin, PhD^5*, Melissa Nhaissi^1*, Candice Rapoport^4*, Stephanie Chinapen^4*, Amanda Kelly^4*, Deborah Wells^1*, Andromachi Scaradavou, MD⁶, Boglarka Gyurkocza, MD^1,7, Esperanza B. Papadopoulos, MD^1,7, Ioannis Politikos, MD^4,8, Brian C. Shaffer, MD^4,8 and Juliet N Barker, MBBS⁸

¹Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
²Equal contribution, New York
³Pediatric Transplantation and Cellular Therapies Service, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY
⁴Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York
⁵Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY
⁶Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY
⁷Department of Medicine, Weill Cornell Medical College, New York, NY
⁸Department of Medicine, Weill Cornell Medicine, New York

Ashima Singh, PhD¹, Mahua Dasgupta, MS^2*, Julie A. Panepinto, MD, MSPH^3,4* and Amanda M. Brandow, DO, MS⁵

¹Department of Pediatrics, Division of Hematology and Oncology, Medical College of Wisconsin, Pewaukee, WI
²Medical College of Wisconsin, Milwaukee, WI
³NIH, Division of Blood Diseases and Resources, National Heart, Lung and Blood Institute, Bethesda, MD
⁴Dr. Panepinto contributed to this article as an employee of the Medical College of Wisconsin. The views expressed are her own and do not necessarily represent the views of the National Institutes of Health or the United States Government, Bethesda, DC
⁵Department of Pediatrics, Section of Hematology/Oncology/Bone Marrow Transplantation, Medical College of Wisconsin and Children’s Research Institute of Children’s Wisconsin, Milwaukee, WI

Paul L. Aronson, MD^1*, Sarah A. Nolan, BA, NRP^2*, Paula Schaeffer, MA^2*, Kimberly Hieftje, PhD^2*, Kortney A. Ponce, BS^3* and Cecelia Calhoun, MD, MPHS, MBA⁴

¹Departments of Pediatrics and Emergency Medicine, Yale School of Medicine, New Haven, CT
²Department of Pediatrics, Yale School of Medicine, New Haven, CT
³California Health Sciences University, College of Osteopathic Medicine, Clovis, CA
⁴Department of Medicine, Yale School of Medicine, New Haven, CT

Arshi Syal, MD^1,2*, Yajur Arya, MD^1,2, Bruce Adrian Casipit, MD^1,2*, Claudia Dourado, MD^1,2, Ryan J Mayo, MD^1,2* and Gordon Heller, DO^1,2*

¹Albert Einstein Medical Center, Philadelphia, PA
²Thomas Jefferson University Hospital, Philadelphia, PA

Savannah Winkler, BSc^1*, Kathryn King, BSc^1*, Robert I. Liem, MD², Jane Holl, MD^3* and Sherif M. Badawy, MD, MBA, MS^1,2

¹Division of Hematology, Oncology, Neuro-Oncology and Stem Cell Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
²Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL
³Department of Neurology and Center for Healthcare Delivery Science and Innovation, University of Chicago, Chicago, IL

Srinivas K. Tantravahi, MBBS¹, Dominick Latremouille-Viau, MSc^2*, Raj Desai, PhD^3*, Soyon Lee, PharmD, MPH^4*, Jincy Paulose, MD^5*, Lincy Geevarghese, MD^6*, Annie Guérin, MS^2*, Shravanthi Seshasayee, MPH^3*, Nadia Tabatabaeepour, MPH^3* and Glorian P. Yen, PhD, MPH^4*

¹Division of Hematology and Hematologic Malignancies, Huntsman Cancer Institute, The University of Utah, Salt Lake Cty, UT
²Groupe d’analyse, Ltée, Montreal, QC, Canada
³Analysis Group, Inc., Boston, MA
⁴Novartis Pharmaceuticals Corporation, East Hanover, NJ
⁵Novartis, East Hanover, NJ
⁶Novartis Pharmaceuticals Corp., East Hanover, NJ

Jennifer Girard, MD, MS¹, Jordan K Schaefer, MD², Charley Jiang, MS^3*, Mana Yacim, MEd^4*, Alexander Janke, MD, MPH^5* and Erica Marsh, MD, MSCI, FACOG^6*

¹Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI
²Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI
³onWHARD Collaborative, University of Michigan, Ann Arbor, MI
⁴Medical School, University of Michigan, Ann Arbor, MI
⁵Emergency Medicine, University of Michigan, Ann Abor, MI
⁶University of Michigan, Ann Arbor, MI

Yaa Ofori-Marfoh, MSc, BS¹, Abhinav Gundala, MS^2*, Arvind Mallikarjunan, MS, BS^3,4*, Richard Faldowski, PhD^5*, John Strouse, MD, PhD^6* and Charity I Oyedeji, MD^7,8,9

¹Rush Medical College of Rush University, Durham, NC
²Nanbar Health LLC, Greenville, NC
³Brody School of Medicine - East Carolina University, Durham, NC
⁴Nanbar Health, LLC, Winterville, NC
⁵Duke University, Durham, NC
⁶Duke University Medical Center, Durham, NC
⁷Duke Adult Comprehensive Sickle Cell Center, Duke University, Durham, NC
⁸Department of Medicine, Division of Hematology, Duke University School of Medicine, Durham, NC
⁹Department of Medicine, Division of Hematology, Duke University, Durham, NC

Emily Abdelmessih, PharmD^1*, Stephanie Wo, PharmD^1*, David L. Green, MD^1,2*, Orly Leiva, MD², Elaine Xiang, PharmD¹ and Tania Ahuja^1,2*

¹NYU Langone Health, New York, NY
²NYU Grossman School of Medicine, NY, NY

Stephanie L Padrick, BSN, RN^1*, Charity I Oyedeji, MD², Reena Ravi, BS^3*, Rania Mohamed, BS^3*, Teagan Callaway, BS^3* and John J Strouse, MD, PhD⁴

¹Department of Medicine, Division of Hematology, Duke University Medical Center, Durham, NC
²Department of Medicine, Division of Hematology, Duke University, Durham, NC
³Duke University Medical Center, Durham, NC
⁴Department of Medicine, Division of Hematology, Duke University School of Medicine, Durham, NC

Jay Vakil, DO¹, Vaishali Deenadayalan, MD¹, Hafeez Shaka, MD^1* and Maryam Zia, MD²

¹John H. Stroger Hospital of Cook County, Chicago, IL
²Division of Hematology and Oncology, John H. Stroger Hospital of Cook County, Chicago, IL

Cheryl Jones, PhD^1*, Yunchou Wu, PhD^1*, Nana Kragh, MSc^2*, Linda Bystrická^2*, Amanda Wilson^3* and Tom Burke, MSc^4*

¹HCD Economics, Knutsford, United Kingdom
²Swedish Orphan Biovitrum AB, Stockholm, Sweden
³Sanofi, Cambridge, MA
⁴HCD Economics, Daresbury, United Kingdom

David Dingli, MD¹, Avery A. Rizio, PhD^2*, Lynne Broderick, MPH^2*, Kaitlin LaGasse, MS^2*, Michelle K. Carty, PhD^2*, Elise Burton^3*, Shaquilla Gordon^4*, Leslie C. Weigand^5*, Glorian P. Yen, PhD, MPH^6*, Jincy Paulose, MD^6*, Lincy Geevarghese^6* and Soyon Lee, PharmD, MPH^6*

¹Mayo Clinic, Rochester, MN
²QualityMetric Incorporated, LLC, Johnston, RI
³No affiliation, New York, NY
⁴No Affiliation, Atlantic Beach, FL
⁵No Affiliation, Binghamton, NY
⁶Novartis Pharmaceuticals Corporation, East Hanover, NJ

Srikanth Nagalla, MBBS^1,2, Shruti Chaturvedi, MBBS³, Moshe Levy^4*, Scott Kolodny, MD^5*, Abiola Oladapo, PhD^6*, Chelsea Bernheisel^5*, Brian Jamieson, MD⁵, Debbie Goldschmidt, PhD^7*, Elyse Swallow^8*, Ali Greatsinger, MPH^7* and Michael Vredenburg, PhD^5*

¹Miami Cancer Institute, Miami, FL
²Baptist Health South Florida, Miami, FL
³Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
⁴Baylor Scott & White Health, Dallas, TX
⁵Sobi, Inc., Durham, NC
⁶Sobi, Inc., Waltham, MA
⁷Analysis Group, Inc., New York, NY
⁸Analysis Group, Inc., Boston, MA

Jennifer N Longoria, PhD^1*, Andrew M Heitzer, PhD^1*, Joshua Semko, MA^1*, Halle T McCracken, MA^1*, Erin MacArthur, MS^1*, Guolian Kang, PhD, MS², Catherine R Hoyt, OTD, PhD^3*, Jane S Hankins, MD, MS⁴ and Clifford M Takemoto, MD⁵

¹Department of Psychology and Biobehavioral Sciences, St. Jude Children's Research Hospital, Memphis, TN
²Department of Biostatistics, St. Jude Children’s Research Hospital, Memphis, TN
³Washington University School of Medicine, St Louis, MO
⁴Departments of Hematology and Global Pediatric Medicine, St. Jude Children’s Research Hospital, Memphis, TN
⁵Department of Hematology, St. Jude Children’s Research Hospital, Memphis, TN

Jordan K Schaefer, MD¹, Josh Errickson, PhD^2*, Xiaowen Kong, MA^3*, Mona A Ali, PharmD^4*, Naina Chipalkatti, MD⁵, Paul Dorby, PharmD^6,7*, Christopher Giuliano, PharmD, MPH^6,7*, Brian Haymart, RN, MS^3*, Scott Kaatz, DO, MSc^8*, Jacob E Kurlander, MD, MS^9*, Gregory D Krol, MD^10*, Sahana Shankar, BS^11*, Suman L Sood, MD, MSCE¹, James Froehlich, MD, MPH^3* and Geoffrey D. Barnes, MD, MSc^3*

¹Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI
²Consulting for Statistics, Computing, & Analytics Research, University of Michigan, Ann Arbor, MI, University of Michigan, Ann Arbor, MI
³Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI
⁴Department of Heart and Vascular Services, Corewell Health William Beaumont University Hospital, Royal Oak, MI
⁵Department of Internal Medicine, University of Michigan, Ann Arbor, MI
⁶Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Science, Wayne State University, Detroit, MI
⁷Ascension St. John Hospital, Detroit, MI
⁸Division of Hospital Medicine, Henry Ford Health, Detroit, MI
⁹Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI
¹⁰Department of Internal Medicine, Henry Ford Health, Detroit, MI
¹¹Oakland University William Beaumont School of Medicine, Rochester, MI

Sydney Forman, BS^1* and Steven J. Hardy, PhD^2,3

¹Division of Hematology, Children's National Hospital, Washington, DC
²Divisions of Hematology and Oncology, Children's National Hospital, Washington, DC
³Departments of Pediatrics and Psychiatry & Behavioral Sciences, George Washington University School of Medicine and Health Sciences, Washington, DC

Nicole Farmer, MD^1*, Ashley Buscetta, MSN, FNP-BC, CWOCN^2*, Ralph Tuason^3*, Stephanie Wildridge^3*, Chantal Gerrard^3*, Li Yang^3*, Sara Turner^3*, Shanna Yang^3*, Alyssa Baginski^3*, Faeben Wossenseged, BS^4*, Allison Brichacek^3*, Hasmin C. Ramirez, MPH^2*, Vence L. Bonham⁵ and Gwenyth R. Wallen^4*

¹National Institutes of Health, Bethesda
²NHGRI, National Institutes of Health, Bethesda, MD
³National Institutes of Health Clinical Center, Bethesda
⁴National Institutes of Health, Bethesda, MD
⁵NIH, Bethesda, MD