-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

641. Chronic Lymphocytic Leukemias: Basic and Translational: Poster III

Symposia: Chronic Lymphocytic Leukemias: Basic and Translational Program: Oral and Poster Abstracts
Type: Poster
Monday, December 11, 2023: 6:00 PM-8:00 PM
Halls G-H (San Diego Convention Center)

Helga Simon-Molas, PhD1,2,3*, Chiara Montironi, MSc1,3,4*, Gaspard Cretenet, PhD1,2,3*, Sjoerd P.P. van Eeden5,6*, Rosita Del Prete7*, Zhenghao Chen4,8,9*, Ingrid A.M. Derks4,9*, Mariska Verlaan5,6*, Arnon P. Kater, MD, PhD2,8, Wissam Beaino5,6*, Anna Kabanova, PhD7*, Josée M. Zijlstra, MD, PhD6,10, Albert D. Windhorst5,6* and Eric Eldering, PhD1,4*

1Experimental Immunology, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands
2Cancer Immunology, Cancer Center Amsterdam, Amsterdam, Netherlands
3Hematology, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands
4Cancer Center Amsterdam, Cancer Immunology, Amsterdam, Netherlands
5Department of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
6Cancer Center Amsterdam, Imaging, Amsterdam, Netherlands
7Toscana Life Sciences Foundation, Siena, Italy
8Department of Hematology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
9Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
10Department of Hematology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands

Aishath Naeem, PhD1,2, Liang Li, MS2*, Filippo Utro, PhD3*, Justin Cha, BS4*, Junko Tsuji, PhD5*, Stacey M Fernandes, BS6*, Roberta Santos Azevedo7,8*, Francesca Morelli, MD1,9*, Zunqiu Wang, MS1*, Samantha J. Shupe, BS1*, Kahn Rhrissorrakrai, PhD3*, Chaya Levovitz, PhD3*, Brian P Danysh, PhD2*, Alexandria Kluge, BS2*, Matthew S. Davids, MD, MMSc1,10, Ignaty Leshchiner, PhD2,11*, Laxmi Parida, PhD3*, Gad Getz, PhD2,12,13,14* and Jennifer R. Brown, MD, PhD1,2,10

1Department of Medical Oncology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA
2Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA
3IBM T.J. Watson Research Center, Yorktown Heights, NY
4Cancer Program, The Broad Institute of MIT and Harvard, Cambridge, MA
5Broad Institute of MIT and Harvard, Cambridge, MA
6Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
7Department of Medical Oncology, Harvard Medical School, Dana-Farber Cancer Institute, Sao Paulo, AC, Brazil
8Department of Hematology, Hospital Nove de Julho, São Paulo, Brazil
9Department of Hematology, University of Florence, Florence, Italy
10Department of Medicine, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA
11Department of Medicine, Section of Computational Biomedicine, Boston University School of Medicine, Boston, MA
12Cancer Center, Massachusetts General Hospital, Boston, MA
13Harvard Medical School, Boston, MA
14Department of Pathology, Massachusetts General Hospital, Boston, MA

Chaja F. Jacobs1,2,3,4*, Fleur S. Peters, PhD1,3,4,5*, Gaspard Cretenet, PhD1,3,4,5*, Noam Zelcer6*, Helga Simon-Molas, PhD1,3,4,5* and Arnon P. Kater, MD, PhD1,3,4,7

1Hematology, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands
2Experimental Immunology, Amsterdam UMC, Amsterdam, Netherlands
3Cancer Immunology, Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands
4Cancer Immunology, Cancer Center Amsterdam, Amsterdam, Netherlands
5Experimental Immunology, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands
6Medical Biochemistry, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands
7Lymphoma and Myeloma Center Amsterdam, Amsterdam, Netherlands

Byeongho Jung, MD1*, Anita Ng, PhD2, Pui Yan Chiu3*, Barbara Sherry, PhD3 and Nicholas Chiorazzi, MD4

1Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY
2Karches Center for Oncology Research, The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY
3Center for Immunology & Inflammation, The Feinstein Institute for Medical Research, Manhasset, NY
4Karches Center for Oncology Research, The Feinstein Institutes for Medical Research, Manhasset, NY

Yeong Jer Lim1,2*, Andrew Duckworth3*, Kim Clarke4*, Paul Kennedy5*, Melanie Oates3*, Matthew Gornall6*, Nagesh Kalakonda1,3*, Joseph Slupsky3* and Andrew Pettitt, MD, PhD1,3*

1The Clatterbridge Cancer Centre NHS Foundation Trust, Liverpool, United Kingdom
2Department of Molecular & Clinical Cancer Medicine, University of Liverpool, Warrington, ENG, United Kingdom
3Department of Molecular & Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom
4Computational Biology Facility, University of Liverpool, Liverpool, United Kingdom
5Department of Pharmacology & Therapeutics, University of Liverpool, Liverpool, United Kingdom
6Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, United Kingdom

Federico Pozzo, PhD1*, Gabriela Forestieri2*, Filippo Vit, PhD3*, Erika Tissino, PhD4*, Tamara Bittolo5*, Robel Papotti6*, Annalisa Gaglio6*, Lodovico Terzi Di Bergamo7*, Agostino Steffan8*, Roberta Laureana9*, Agostino Tafuri, MD10, Annalisa Chiarenza, MD11*, Francesco Di Raimondo, MD12, Jacopo Olivieri13*, Francesco Zaja, MD14*, Luca Laurenti, MD15*, Maria Ilaria Del Principe, MD16*, Riccardo Bomben5*, Antonella Zucchetto, PhD17*, Davide Rossi18 and Valter Gattei, MD19

1Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano, Aviano, Italy
2Laboratory of Experimental Hematology, Institute of Oncology Research, Bellinzona, Switzerland
3Clinical and Experimental Onco-Haematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy, ITA
4Clinical and Experimental Onco-Hematology Unit, Centro Di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy
5CRO Aviano National Cancer Institute,Clinical and Experimental Onco-Hematology Unit, Aviano, Italy
6Clinical and Experimental Onco-Haematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy
7Institute of Oncology Research, Bellinzona, CHE
8IRCCS National Cancer Institute, Aviano, PN, ITA
9Division of Haematology, University of Tor Vergata, Rome, Roma, ITA
10Department of Clinical and Molecular Medicine and Hematology, Sant'Andrea - University Hospital - Sapienza, University of Rome, Rome, Italy
11Division of Hematology, Policlinico, Department of Surgery and Medical Specialties, University of Catania, Catania, Catania, Italy
12Division of Hematology, Policlinico, Department of Surgery and Medical Specialties, University of Catania, Catania, ITA
13Clinica Ematologica, Centro Trapianti e Terapie Cellulari "Carlo Melzi", Azienda Sanitaria Universitaria Integrata di Udine, Udine, Italy
14DSM, University of Trieste, Trieste, Italy
15Istituto di Ematologia, Rome, ITA
16Hematology, Department of Biomedicine and Prevention, University Tor Vergata, Roma, Italy
17Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy
18Clinic of Hematology, Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland
19Centro Di Riferimento Oncologico, Aviano, Italy

Zheng Tian1*, Ya Zhang, MD2,3*, Hua Wang, MS3*, Liyan Lu, MS3* and Xin Wang, MD, PhD2,3

1Department of Hematology, Shandong Provincial Hospital, Shandong University, Jinan, AL, China
2Department of Hematology, Shandong Provincial Hospital, Shandong University, Jinan, China
3Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China

Nienke B. Goedhart, MSc1,2,3,4*, Helga Simon-Molas, PhD1,3,5,6*, Chiara Montironi, MSc1,2,3,4*, Chaja F. Jacobs3,5,6,7*, Elena Camerini, MSc1,2,3,4*, Jaco A.C. Van Bruggen, PhD1,2,3,4*, Gaspard Cretenet, PhD1,3,5,6*, Eric Eldering, PhD1,2,4*, Fleur S. Peters, PhD1,3,5,6* and Arnon P. Kater, MD, PhD3,5,6,8

1Experimental Immunology, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands
2Cancer Center Amsterdam, Cancer Immunology, Amsterdam, Netherlands
3Hematology, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands
4Amsterdam Institute for Infection and Immunity, Cancer Immunology, Amsterdam, Netherlands
5Cancer Immunology, Cancer Center Amsterdam, Amsterdam, Netherlands
6Cancer Immunology, Amsterdam Institute for Infection and Immunity, Amsterdam, Netherlands
7Experimental Immunology, Amsterdam UMC, Amsterdam, Netherlands
8Lymphoma and Myeloma Center Amsterdam, Amsterdam, Netherlands

Sydney A Skupa, BS1*, Audrey L Smith, BS1, Alexandria P Eiken, BS1*, Elizabeth A Schmitz, BS1*, Kathryn M Cooper, PhD2*, Christopher R D'Angelo, MD3 and Dalia El-Gamal, PhD, MSc4

1Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE
2School of Interdisciplinary Informatics, University of Nebraska at Omaha, Omaha, NE
3Fred and Pamela Buffett Cancer Center/Division of Hematology and Oncology/Department of Internal Medicine, University of Nebraska Medical Center, Bennington, NE
4Eppley Cancer Institute, University of Nebraska Medical Center, Omaha, NE

Shanmugapriya Thangavadivel, PhD1*, Charlene Mao, MS2*, Meixiao Long, MD, PhD3, Shrilekha Misra, PhD2*, Samon Benrashid, BS2*, Britten Gordon, BS2, Alexander He, BS2*, Tzung-Huei Lai, PhD2*, Kerry A Rogers, MD1, Seema A Bhat, MD1, Adam S Kittai, MD1, John C. Byrd, MD4 and Jennifer A. Woyach, MD5

1Division of Hematology, The Ohio State University, Columbus, OH
2The Ohio State University, Columbus, OH
3Division of Hematology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH
4Department of Internal Medicine, University of Cincinnati, Cincinnati, OH
5The Ohio State University Comprehensive Cancer Center, Columbus, OH

Gonzalo Blanco1*, Xiao J. Yan, MD, PhD1, Anita Ng, PhD1, Andrew Shih2*, Jonathan E Kolitz, MD3, Jacqueline C. Barrientos, MD3, Steven L. Allen, MD3, Joanna M. Rhodes, MD3, Kanti R. Rai, MD3 and Nicholas Chiorazzi, MD1

1Karches Center for Oncology Research, The Feinstein Institutes for Medical Research, Manhasset, NY
2Robert S. Boas Center for Genomics and Human Genetics, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, Manhasset, NY
3Department of Medicine, Northwell Health, Manhasset, NY

Thi Huong Lan Do, MSc1,2*, Caroline Lohoff3,4*, Ferris Jung5*, Vladimir Benes5*, Wolfgang Huber4*, Junyan Lu3,4* and Thorsten Zenz2,6,7

1Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Zurich, Switzerland
2University of Zurich (UZH), Zurich, Switzerland
3Medical Faculty Heidelberg, Heidelberg University Hospital, Heidelberg, Germany
4Genome Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany
5Genomic Core Facility, European Molecular Biology Laboratory, Heidelberg, Germany
6Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland
7INTeRCepT Consortium, The LOOP Zurich Medical Research Center, Zurich, Switzerland

*signifies non-member of ASH