John C. Byrd, MD¹, Dariusz Woszczyk, MD^2*, Arpad Illes, MD^3*, Wojciech Jurczak, MD, PhD^4*, Dominik Chraniuk^5*, Krzysztof Giannopoulos, MD^6*, Nataliia Mikhailova^7*, Peter Illconzai^8*, Seema A Bhat, MD⁹, Nataliya Romanyuk^10*, Ganna Usenko, MD^11*, Olha Kuchkova^12*, Jason Chandler, MD¹³, Elizabeth Bilotti^14*, Annalise Shen^14*, Jean Cheung^14*, Srdan Verstovsek, MD, PhD^14*, Jesse McGreivy^14*, Wayne Rothbaum, MS^14* and Maciej Kaźmierczak, MD^15*

¹Department of Internal Medicine, University of Cincinnati, Cincinnati, OH
²University of Opole, Provincial Hospital, Opole, Poland
³Department of Hematology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
⁴MSC National Research Institute of Oncology, Krakow, Poland
⁵Department of Hematology, Wojewodzki Szpital Zespolony, Torun, Poland
⁶Gabinety Lekarskie Hema, Lublin, Poland
⁷First Pavlov State Medical University of St.Petersburg, Saint Petersburg, Russian Federation
⁸Markoth Ferenc Hospital, Kazincbarcika, Hungary
⁹The Ohio State University, Columbus, OH
¹⁰Mykolaiv Regional Clinical Hospital, Mykolaiv, UKR
¹¹MNE City Clinical Hospital#4 of DCC, Dnipro, UKR
¹²Communal Non-Profit Enterprise “Regional Center Of Oncology”, Kyiv, Ukraine
¹³West Cancer Center & Research Institute, Germantown, TN
¹⁴Kartos Therapeutics, Inc., Redwood City, CA
¹⁵Centrum Medyczne Pratia, Poznan, Poland

Nitin Jain, MD¹, Michael J. Keating, MBBS¹, Philip A. Thompson, MBBS^2*, Alessandra Ferrajoli, MD¹, Jayastu Senapati, MD, MBBS, DM¹, Jan A. Burger, MD, PhD ³, Gautam Borthakur, MD¹, Mahesh Swaminathan, MD^1*, Koichi Takahashi, MD, PhD¹, Zeev Estrov, MD¹, Marina Y. Konopleva, MD, PhD^1*, Koji Sasaki, MD¹, Tapan M. Kadia, MD¹, Naveen Pemmaraju, MD¹, Naval Daver, MD¹, Elias Jabbour¹, Courtney D. DiNardo, MD, MSc¹, Yesid Alvarado Valero, MD¹, Musa Yilmaz, MD^1*, Prithviraj Bose, MD¹, Maro Ohanian, DO^1*, Rashmi Kanagal-Shamanna, MD⁴, Keyur Patel, MD, PhD^4*, Jeffrey L. Jorgensen, MD⁴, Sa A. Wang⁴, Sameh Nassar, MD^5*, Naveen Garg, MD^5*, Hyunsoo Hwang, MS^6*, Xuemei Wang, MS^6*, Nichole Cruz, RN^1*, Ana Ayala, RN^1*, William Plunkett, PhD⁷, Hagop M. Kantarjian, MD¹, Varsha Gandhi, PhD⁸ and William G. Wierda, MD, PhD¹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Peter MacCallum Cancer Center, Royal Melbourne Hospital and University of Melbourne, Melbourne, Australia
³Department of Leukemia, MD Anderson Cancer Center, Houston, TX
⁴Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Department of Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX
⁶Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX
⁸Department of Experimental Therapeutics, MD Anderson Cancer Center, Houston, TX

Anita Sarma, MBBS^1*, Charlotte Evans, PhD^2*, Surita Dalal, PhD^1,2*, Nichola Webster^1,2*, Andy Rawstron, PhD^1*, Jane Shingles, PhD^1*, Darren Newton, PhD^3*, David Allan Cairns, PhD^4,5*, Paul Glover, MSc^1*, Thomas Grand^1*, Helen Warren^1*, Sue Bell^5*, Sean Girvan^5*, Natasha Greatorex^5*, Anna Hockaday^5*, Sharon Jackson^5*, David Phillips^5*, David Stones^5*, David Allsup, MD^6*, Adrian John Clifton Bloor, PhD, FRCPath, FRCP^7*, Abraham Mullasseril Varghese, MBBS, MRCP^8*, Talha Munir, MBBS, MRCP, FRCPath, PhD^9* and Peter Hillmen, MB ChB, PhD¹⁰

¹HMDS, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
²Leeds Institute of Medical Research, University of Leeds, Leeds, United Kingdom
³Leeds Institute of Medical Research, University of Leeds, Leeds, ENG, United Kingdom
⁴Leeds Institute of Clinical Trials Research, Cancer Research UK Clinical Trials Unit, Leeds, ENG, United Kingdom
⁵Leeds Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, United Kingdom
⁶Castle Hill Hospital, Cottingham, GBR
⁷Haematology and Transplant Unit, Christie NHS Foundation Trust, Manchester, United Kingdom
⁸Department of Haematology, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
⁹Department of Haematology, St. James's University Hospital, Leeds, United Kingdom
¹⁰Leeds Institute of Medical Research, St. James's University Hospital, Leeds, United Kingdom

Surita Dalal, PhD^1,2*, Anita Sarma, MBBS^1*, Jane Shingles, PhD^1*, Paul Glover, MSc^1*, Helen Warren^1*, Thomas Grand^1*, Nichola Webster^1,2*, Andy Rawstron^1*, Darren Newton, PhD^3*, Sue Bell^4*, David Allan Cairns, PhD^4*, Sean Girvan^4*, Natasha Greatorex^4*, Anna Hockaday^4*, Sharon Jackson^4*, David Phillips^4*, David Stones^4*, David Allsup, MD^5*, Adrian John Clifton Bloor, PhD, FRCPath, FRCP^6*, Abraham Mullasseril Varghese, MBBS, MRCP^7*, Talha Munir, MBBS, MRCP, FRCPath, PhD^8* and Peter Hillmen, MB ChB, PhD⁹

¹HMDS, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
²Leeds Institute of Medical Research, University of Leeds, Leeds, United Kingdom
³Leeds Institute of Medical Research, University of Leeds, Leeds, ENG, United Kingdom
⁴Leeds Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, United Kingdom
⁵Castle Hill Hospital, Cottingham, GBR
⁶Haematology and Transplant Unit, Christie NHS Foundation Trust, Manchester, United Kingdom
⁷Department of Haematology, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
⁸Department of Haematology, St. James's University Hospital, Leeds, United Kingdom
⁹Leeds Institute of Medical Research, St. James's University Hospital, Leeds, United Kingdom

Shaomei Feng^1*, Teng Xu^2*, Haidi Liu^3*, Peihao Zheng^4*, Lixia Ma^4*, Hui SHI^5*, Tong Wu, MD⁶, Fan Yang^5*, Kai HU^7* and Xiaoyan Ke^8*

¹Department of Lymphoma and Myeloma Research Center, Beijing Gobroad Boren Hospital, beijing, China
²Department of Data Management, Beijing Gaobo Boren Hospital, Beijing, China
³Beijing Boren Hospital, Beijing, CHN
⁴Department of Lymphoma and Myeloma Research Center, Beijing Gobroad Boren Hospital, Beijing, China
⁵Beijing Gobroad Boren Hospital, beijing, China
⁶Department of Bone Marrow Transplantation, Beijing Gobroad Boren Hospital, Beijing, China
⁷Department of Adult Lymphoma, Beijing Boren Hospital, Beijing, China
⁸Department of Lymphoma and Myeloma Research Center, Beijing Gobroad Boren Hospital, Beijing, China

Othman Al-Sawaf, MD¹, Moritz Fürstenau, MD^2*, Adam Giza^1*, Sandra Robrecht, PhD^1*, Julia Von Tresckow, MD^3*, Anna Maria Fink, MD^1*, Florian Simon, MD^4*, Eugen Tausch, MD^5*, Christof Schneider, MD^6*, Liliya Sivcheva, MD^7*, Anthony Schwarer^8*, Javier Loscertales^9*, Robert Weinkove, PhD^10*, Dirk Strumberg^11*, Allanah R. Kilfoyle¹², Gunnar Juliusson, MD, PhD¹³, Caspar Da Cunha-Bang, MD, PhD^14*, Thomas Illmer, MD^15*, Michael Gregor^16*, Patrick Thornton^17*, Ann Janssens, MD^18*, Tamar Tadmor^19*, Vesa Lindström^20*, Philipp Bernhard Staber, MD, PhD²¹, Mark-David Levin, MD, PhD²², Clemens-Martin Wendtner, MD^23*, Karl-Anton Kreuzer^24*, Matthias Ritgen^25*, Stephan Stilgenbauer, MD²⁶, Arnon P. Kater, MD, PhD²⁷, Carsten Utoft Niemann, MD, PhD^28*, Kirsten Fischer, MD^1*, Barbara F. Eichhorst, MD²⁹ and Michael Hallek, MD^30*

¹Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf; German CLL Study Group, University of Cologne, Cologne, Germany
²Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf; German CLL Study Group, University of Cologne, Koeln, Germany
³Clinic for Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
⁴Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf; German CLL Study Group, University of Cologne, Cologne, AL, Germany
⁵Department of Internal Medicine III, Division of CLL, Ulm University, Ulm, Germany
⁶Division of CLL, Department of Internal Medicine III, University of Ulm, Ulm, Germany
⁷First Department of Internal Medicine, Multiprofile Hospital for Active Treatment - HristoBotev, Vratsa, Bulgaria
⁸Box Hill Hospital, Melbourne, AUS
⁹Hospital Universitario De La Princesa, Madrid, ESP
¹⁰Wellington Te Rerenga Ora Blood and Cancer Centre, Capital & Coast District Health Board, Wellington, New Zealand
¹¹Marien Hospital, Herne, DEU
¹²Palmerston North Hospital, Palmerston North, NZL
¹³Department of Hematology, Lund University Cancer Center, Lund, Sweden
¹⁴Rigshospitalet, Copenhagen, Denmark
¹⁵Hematology Private Practice, Dresden, Germany
¹⁶Division of Hematology, Cantonal Hospital of Lucerne, Lucerne, Switzerland, Luzern, Switzerland
¹⁷Department of Haematology, Beaumont Hospital, RCSI, Cancer Trials Ireland, Dublin, Dublin, IRL
¹⁸University Hospitals Leuven, Leuven, Belgium
¹⁹Hematology, Bnai-Zion Medical Center, Haifa, Haifa, Israel
²⁰Comprehensive Cancer Center, Department of Hematology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
²¹Department of Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria
²²Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, Netherlands
²³Department of Hematology, Oncology, Immunology, Palliative Care, Infectious Diseases and Tropical Medicine, German CLL Study Group, Munich Clinic Schwabing, Munich, Germany
²⁴Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf; German CLL Study Group, University of Cologne, Cologne, Cologne, DEU
²⁵Department II of Internal Medicine, University of Schleswig-Holstein, Kiel, Germany
²⁶Department of Internal Medicine III, Division of CLL, University Hospital Ulm, Ulm, Germany
²⁷Academic Medical Center, Amsterdam Zuidoost, NH, Netherlands
²⁸Department of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
²⁹University of Cologne, Cologne, Germany
³⁰Center of Integrated Oncology Aachen Bonn Cologne Duesseldorf (ABCD), University Hospital Cologne, Cologne, Germany, Cologne, Germany

Tamar Tadmor^1,2*, Ohad Benjamini^3*, Neta Goldschmidt^4*, Natalia Kreiniz, MD^5*, Osnat Bairey^6*, Reut Harel, MD^7*, Tsofia Inbar^8*, Ofir Wolach, MD^9,10* and Yair Herishanu, MD^11*

¹Technion, Ruth and Bruce Rappaport Faculty of Medicine,, Haifa,, Israel
²Hematology, Bnai-Zion Medical Center, Haifa, Haifa, ISR
³Sheba Medical Center–Tel HaShomer, Ramat Gan, Israel
⁴Department of Hematology, Hadassah Medical Center, Jerusalem, Jerusalem, ISR
⁵Hematology, Bnai Zion Medical Center, Haifa, Israel
⁶Davidoff Cancer Center, Rabin Medical Center,, Petach Tikva, ISR
⁷Department of Hematology, Emek Medical Center, Afula, Ein-Dor, Israel
⁸Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus,, Haifa, Israel
⁹Institute of Hematology, Davidoff Cancer Center, Rabin Medical Center, Petah-Tikva, Israel
¹⁰Rabin Medical Center, Institute of Hematology, Davidoff Cancer Center, Petah Tikva, Israel
¹¹Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel

Therese Aurran-Schleinitz^1*, Stephen P Mulligan, MBBS, PhD, FRACP, FRCPA², Remi Letestu^3*, Marie Christine Bene^4*, Gavin Cull, MB, BS, FRACP, FRCPA⁵, Jean Pierre Vilque, MD^6*, Constantine S. Tam, MD, MBBS⁷, Sophie De Guibert^8*, Rosemary Anne Harrup^9*, Bernard Drenou, MD^10*, Andrew P Grigg, MBBS, MD, FRACP, FRCPA^11*, Laurent Voillat^12*, Belinda E Butcher, PhD^13*, Caroline Dartigeas^14*, Richard Eek, MBChB, MMed^15*, Nicolas Daguindau^16*, Cecily Forsyth, FRACP, FRCPA, MBBS¹⁷, Mourad Tiab, MD^18*, Delaine Smith, BSc, RN^19*, Jennifer Curnow, MBBS, FRACP, FRCPA, PhD^20*, Veronique Leblond, MD^21*, Stephen Robert Larsen, MBBS²², Florence Cymbalista, MD, PhD^23* and David Gottlieb, MD, MBBS, FRACP, FRCPA^24*

¹Institut Paoli Calmettes, Marseille, France
²University of Sydney, Sydney, NSW, AUS
³APHP, Avicennes Hospital, Bobigny, FM, FRA
⁴Hopital Hotel Dieu & Hme, Nantes, France
⁵Sir Charles Gairdner Hospital Hematology Care Centre, Nedlands, WEA, AUS
⁶CHU Caen, Caen, FRA
⁷The Alfred Hospital and Monash University, Melbourne, VIC, Australia
⁸Centre Hospitalier Pontchaillou, Rennes, FRA
⁹Royal Hobart Hospital, University of Tasmania, Tasmania, Australia
¹⁰HôPital Emile Muller, Mulhouse Cedex 1, FRA
¹¹Austin Hospital, Melbourne, VIC, AUS
¹²Ch William Morey, Chalon Sur Saone, Fr, FRA
¹³ALLG, Lane Cove, NSW, AUS
¹⁴CHU Bretonneau, Tours, FRA
¹⁵Department of Haematology, Border Medical Oncology, New South Wales, Australia, Wodonga, AUS
¹⁶Hematologie, Centre Hospitalier Annecy Genevois, Metz-Tessy, FRA
¹⁷Wyong Hospital, North Gosford, AUS
¹⁸Centre Hospitalier Departemental, La Roche Sur Yon Cedex 9, FRA
¹⁹Australasian Leukemia and Lymphoma Group, Melbourne, VIC, AUS
²⁰Westmead Hospital, Sydney, AUS
²¹APHP, La pitié salpétriere, Paris, FRA
²²Royal Prince Alfred Hospital, Camperdown, Australia
²³Bobigny: Hématologie, CHU Avicennes, Bobigny, France
²⁴Department of Haematology, Westmead Hospital, Sydney, AUS

Huayuan Zhu^1*, Yi Miao, MD^1*, Yi Xia, MD, PhD^1*, Shuchao Qin^1*, Wei Wu^1*, Tonglu Qiu^1*, Chong-Yang Ding^2*, Hairong Qiu^3*, Chun Qiao^4*, Yujie Wu^3*, Fei Li^5*, Wei Xu^1* and Jianyong Li, MD¹

¹Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
²Department of Nuclear Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, CHN
³Department of Hematology, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
⁴Department of Hematology, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, CHN
⁵The First Affiliated Hospital of Nanchang University, Nanchang, China

Jeff P. Sharman, MD¹, Paolo Ghia, MD, PhD², Paulo Andre P. Palhares De Miranda, MD³, Naghmana Bajwa^4*, Simon Rule, MD^5*, Bob Shaw^6* and John F. Seymour, MBBS, PhD, FRACP⁷

¹Willamette Valley Cancer Institute and Research Center/US Oncology Research, Eugene, OR
²Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Milan, Italy
³AstraZeneca, Gaithersburg, MD
⁴AstraZeneca, Wilmington, DE
⁵AstraZeneca, Mississauga, ON, Canada
⁶AstraZeneca, Cambridge, United Kingdom
⁷Peter Maccallum Cancer Centre, Royal Melbourne Hospital and University of Melbourne, Melbourne, Victoria, AUS

Nadine Kutsch, MD^1*, Rudy Ligtvoet, PhD^1*, Sandra Robrecht, PhD^1*, Hartmut Linde, MD^2*, Thomas Illmer, MD^3*, Steffen Doerfel, MD^4*, Joerg Lipke, MD^5*, Ali Aldaoud, MD^6*, Rudolf Schlag, MD^7*, Jolanta Dengler, MD^8*, Othman Al-Sawaf, MD¹, Petra Langerbeins^1*, Paula Cramer, MD^1*, Barbara F. Eichhorst, MD⁹, Michael Hallek, MD^10*, Kirsten Fischer, MD^1* and Anna Maria Fink, MD^1*

¹Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf; German CLL Study Group, University of Cologne, Cologne, Germany
²Practice for Hematology and Oncology Potsdam, Potsdam, Germany
³Hematology Private Practice, Dresden, Germany
⁴Center for Oncology Dresden, Freiberg, Meißen, Dresden, Freiberg, Meißen, Germany
⁵Practice for Hematology and Oncology, Dortmund, Cologne, Germany
⁶Practice for Hematology and Oncology Leipzig, Leipzig, Germany
⁷Practice for Hematology and Oncology Wuerzburg, Wuerzburg, Germany
⁸Practice for Oncology Heilbronn, Heilbronn, Germany
⁹University of Cologne, Cologne, Germany
¹⁰Faculty of Medicine and Cologne University Hospital, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Cologne, Germany, Cologne, Germany

George Follows^1*, Alessandra Ferrajoli, MD², John C. Byrd, MD³, Bob Shaw^4*, Kenji Nozaki^5*, Katherine Stewart^6*, Paulo Andre P. Palhares De Miranda, MD⁶ and Jeff P. Sharman, MD⁷

¹Department of Haematology, Addenbrooke’s Hospital NHS Trust, Cambridge, United Kingdom
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Internal Medicine, University of Cincinnati, Cincinnati, OH
⁴AstraZeneca, Cambridge, United Kingdom
⁵AstraZeneca, Osaka, Japan
⁶AstraZeneca, Gaithersburg, MD
⁷Willamette Valley Cancer Institute and Research Center/US Oncology Research, Eugene, OR

Alessandra Tedeschi^1*, Andrea Galitzia^2*, Annamaria Frustaci^3*, Caterina Patti, MD^4*, Alessandro Sanna, MD^5*, Lorena Appio^6*, Luana Schiattone^7*, Paolo Sportoletti, MD^8*, Claudia Barate'^9*, Beatrice Casadei, MD, PhD^10*, Isacco Ferrarini, MD, PhD^11*, Amalia Figuera^12*, Caterina Stelitano^13*, Giacomo Loseto, MD^14*, Andrea Visentin, MD, PhD^15*, Marta Coscia, MD, PhD^16*, Riccardo Moia, MD^17*, Marina Motta, MD^18*, Filomena Russo^19*, Monica Tani^20*, Enrico Capochiani, MD^21*, Angela Ferrari^22*, Massimo Gentile, MD^23*, Roberta Giacchetti^24*, Annamaria Giordano, MD^25*, Vanessa Innao^26*, Marzia Varettoni^27*, Federico Vozzella^28*, Francesca Cibien^29*, Daniela Gottardi, MD^30*, Enrico Lista^31*, Laura Nocilli^32*, Cristina Pasquini^33*, Anna Vanazzi, MD^34*, Elisa Santambrogio^35*, Roberta Murru, MD^36*, Francesca Romana Mauro^37*, Mariano Lucignano^38* and Luca Laurenti, MD^39*

¹ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy
²Departement of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy
³Department of Hematology, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy
⁴Division of Hematology 1, Azienda Ospedali Riunita Villa Sofia-Cervello, Palermo, Italy
⁵Hematology, AOU Careggi, Florence, Italy
⁶ASST Valle Olona, Busto Arsizio, Busto Arsizio, ITA
⁷UOSD Centro Diagnosi e Terapia dei Linfomi, Presidio Ospedaliero Santo Spirito, Pescara, Italy
⁸Department of Medicine and Surgery, Institute of Hematology, Centro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, Italy
⁹Department of Clinical and Experimental Medicine, Section of Hematology, University of Pisa, Pisa, Italy, Pisa, ITA
¹⁰Hematology, Istituto di Ematologia “Seràgnoli”, Bologna, Italy
¹¹A.O.U. Integrata di Verona – Borgo Roma,, Verona, Italy
¹²Division of Hematology, AOU “Policlinico-Vittorio Emanuele,” University of Catania, Catania, ITA
¹³Department of Hematology, Azienda Ospedaliera Bianchi Melacrinò Morelli, Reggio Calabria, Reggio Calabria, Italy
¹⁴IRCCS Istituto Tumori “Giovanni Paolo II”, Hematology Unit, Bari, Italy
¹⁵Hematology unit, Department of Medicine, University of Padova, Padova, Italy
¹⁶Division of Hematology, A.O.U. Città della Salute e della Scienza di Torino and Department of Molecular Biotechnology and Health Sciences, University of Torino, Turin, Italy
¹⁷Division of Hematology, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Novara, Italy
¹⁸Hematology, ASST Spedali Civili, Brescia, Italy
¹⁹AOU Ospedale Maggiore di Parma, Parma, ITA
²⁰Santa Maria delle Croci Hospital, Ravenna, Italy
²¹Hematology Unit, Center for Translational Medicine, Azienda USL Toscana NordOvest, Livorno, ITA
²²IRCCS - Arcispedale Santa Maria Nuova, Hematology, ITA, Reggio Emilia, Italy
²³Department of Onco-Hematology, Hematology Unit AO of Cosenza, Cosenza, Italy
²⁴SOS Oncoematologia Pistoia e Pescia, Pescia, Italy
²⁵Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), Hematology and Stem Cell Transplantation Unit, University of Bari "Aldo Moro", Bari, Italy
²⁶University of Messina, Messina, ITA
²⁷Division of Hematology, Fondazione IRCCS Policlinico S. Matteo University of Pavia, Pavia, Italy
²⁸Hematology, Department of Translational and Precision Medicine, Azienda Ospedaliera Policlinico Umberto I, Sapienza University of Rome, Roma, ITA
²⁹Hematology, Ospedale Ca' Foncello, Treviso, ITA
³⁰University Division of Hematology and Cellular Therapy, A.O. Ordine Mauriziano, TORINO, ITA
³¹Department of Hematology, Santa Chiara Hospital, Trento, Italy, Trento, ITA
³²Hematology, Azienda Ospedaliera Papardo, Messina, Italy
³³UO Oncologia, Ospedale Maggiore, Crema, Italy., Crema, Italy
³⁴Clinical Hemato-Oncology, Istituto Europeo di Oncologia IRCCS, Milano, Italy
³⁵Istituto Di Candiolo, FPO-IRCCS, Candiolo, ITA
³⁶Hematology and Stem Cell Transplantation Unit, Ospedale Oncologico A. Businco, ARNAS "G. Brotzu", Cagliari, Italy
³⁷Department of Translational and Precision Medicine, Hematology unit, 'Sapienza' University, Roma, Italy
³⁸Hematology, AOU Federico II, Naples, ITA
³⁹S. Ematologia, Dipartimento Scienze Radiologiche Radioterapiche ed Ematologiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy

Stefano Molica, MD^1*, Tait D. Shanafelt, MD², David Allsup, MD^3* and Diana Giannarelli, PhD^4*

¹Department Hematology, Hull University Teaching Hospitals NHS Trust, Hull, UK, Department Hematology, Hull University Teaching Hospitals NHS Trust, Hull, UK, Hull, United Kingdom
²Department of Medicine, Division of Hematology, Stanford University, Stanford, CA
³Castle Hill Hospital, Cottingham, GBR
⁴Biostatistics Unit,, b Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy, Rome, Italy

Chenyu Lin, MD^1,2, Clare E Anderson, MD^1,3*, Micaela R Scobie, PhD^4*, Thomas D Rodgers, MD^1,2, Michael J Kelley, MD^1,4,5* and Daphne R Friedman, MD^1,4,5

¹Durham VA Medical Center, Durham, NC
²Division of Hematologic Malignancies and Cellular Therapy, Duke University School of Medicine, Durham, NC
³Department of Medicine, Duke University School of Medicine, Durham, NC
⁴National Oncology Program, Department of Veterans Affairs, Washington, DC
⁵Division of Medical Oncology, Duke University School of Medicine, Durham, NC

Jennifer Prescott^1*, Torben Steiniche^2*, Jeanette Bæhr Georgsen^2*, Lene Hyldahl Ebbesen^2*, Jens Kanstrup Kjær^2*, Magdalena Snopekova^3*, Laura H. Lorentsen^3*, Tobias Ramm Eberlein^3*, Robert Schou Pedersen^3*, Mohammed Z.H. Farooqui, DO¹, Bo Wei^1*, Razvan Cristescu^1*, Nicole Myer^1*, Mette Kehlet^1* and Francesco Annibale d'Amore²

¹Merck & Co., Inc., Rahway, NJ
²Aarhus University Hospital, Aarhus, Denmark
³Gødstrup Hospital, Herning, Denmark

Laura Samples, MD¹, Chaitra S Ujjani, MD², Sirin Khajaviyan, MD^3*, Ryan C Lynch, MD^4,5, Mehrdad Shakib-Azar^3*, Christine Crider^3*, Margie Fredericks, MSN, ARNP^6*, Stephanie Louie, RN^6*, Christina Poh, MD³, Stephen D Smith, MD^4,7, Brian G Till³, David G Maloney, MD, PhD³, Ajay K Gopal, MD^2,4 and Mazyar Shadman, MD, MPH³

¹Fred Hutchinson Cancer Center and University of Washington School of Medicine, Seattle, WA
²Clinical Research Division, Fred Hutch Cancer Center; and Division of Oncology, University of Washington, Seattle, WA
³Fred Hutchinson Cancer Center, Seattle, WA
⁴Division of Hematology and Oncology, University of Washington, Seattle, WA
⁵Fred Hutch Cancer Center, Seattle, WA
⁶Fred Hutchinson Cancer Center, Seattle
⁷Fred Hutchinson Cancer Center, University of Washington, Seattle, WA

Chung-Jiah J. Chen¹, Michael Y. Choi, MD², Benjamin M. Heyman, MD² and Thomas J. Kipps, MD, PhD³

¹Division of Hematology/Oncology, Department of Medicine, University of California San Diego, La Jolla, CA
²Moores Cancer Center, University of California San Diego, La Jolla, CA
³UC San Diego Moores Cancer Center, Duarte, CA

Kevin H. Lin, MD, PhD^1*, Lynn Huynh, DrPH, MBA, MPH^2*, Xiaoqin Yang, PhD^3*, Enrico Zanardo, PhD^4*, Lisa Matay, BA^2*, Megan Pinaire, MPH^2*, Daria Liborski, BS^1*, Mikaela M. McDonough, BS^1*, Jillian Foreman, BS^1*, Mohammed Z.H. Farooqui, DO³, Enrico De Nigris, MSc^5*, Shravanthi R. Gandra, PhD, MBA^3*, Eric M. Sarpong, PhD^3*, Mei Sheng Duh, RPh, MPH, ScD², Jennifer R. Brown, MD, PhD¹ and Matthew S. Davids, MD, MMSc¹

¹Dana-Farber Cancer Institute, Boston, MA
²Analysis Group, Inc., Boston, MA
³Merck & Co., Inc., Rahway, NJ
⁴Analysis Group, Denver, CO
⁵MSD, London, United Kingdom

Huayuan Zhu^1*, Luomengjia Dai, MD^2*, Yeqin Sha^1*, Xiao Lu^3*, Siqi Qian^2*, Tonglu Qiu^1*, Yi Miao, MD^1*, Yi Xia, MD, PhD^1*, Shuchao Qin^1*, Ziyuan Zhou^1*, Wei Wu^1*, Lei Fan, MD^1*, Wei Xu^1* and Jianyong Li, MD¹

¹Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
²Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, AL, China
³Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, NY, China

Ingo Schwaner^1*, Holger F. Hebart, MD², Christoph Losem^3*, Thomas Wolff, MD^4*, Caroline Lehmann^5*, Johannes Huelsenbeck^6*, Burkhard Schmidt^7*, Petra Pichler, MD^8* and Davide Rossi⁹

¹Onkologie Kurfürstendamm, Berlin, DEU
²Stauferklinikum, Mutlangen, Mutlangen, DEU
³TZN Tumorzentrum Niederrhein GmbH, Germany, Neuss, DEU
⁴Onkologie-Lerchenfeld, Hamburg, DEU
⁵AbbVie Deutschland GmbH & Co. KG, Wiesbaden, Germany
⁶AbbVie Deutschland GmbH & Co. KG, Hämatologie, Wiesbaden, Germany
⁷Hämatologie und Onkologie München-Pasing MVZ GmbH, Santa Monica, CA
⁸Department of Internal Medicine I: Hematology & Oncology, University Hospital St. Poelten, Karl Landsteiner University of Health Sciences, St. Poelten, AUT
⁹Clinic of Hematology, Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland

Mazyar Shadman, MD, MPH¹, Alessandra Tedeschi^2*, Leyla Mohseninejad, PhD^3*, Keri Yang, PhD, MBA, MPH, MS, CPM, BSPharm^4*, Nicole Lamanna, MD⁵, Sheng Xu^6*, Aileen Cleary Cohen, MD, PhD⁴, Swetha Challagulla, MS^4*, Mei Xue, MBA^4*, Rhys Williams^4*, Susan M. O'Brien⁷, Jennifer R. Brown, MD, PhD⁸ and Constantine S. Tam, MD, MBBS⁹

¹Fred Hutchinson Cancer Center, Seattle, WA
²ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy
³BeiGene Netherlands B.V., Schiphol, Netherlands
⁴BeiGene USA, Inc, San Mateo, CA
⁵Herbert Irving Comprehensive Cancer Center, New York-Presbyterian/Columbia University Medical Center, New York, NY
⁶BeiGene (Shanghai) Co., Ltd., Shanghai, China
⁷University of California, Irvine, CA
⁸Chronic Lymphocytic Leukemia Center, Division of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA
⁹Alfred Hospital and University of Melbourne, Melbourne, VIC, Australia

Laura Samples, MD¹, Sirin Khajaviyan, MD^2*, Ryan C Lynch, MD^3,4, Mehrdad Shakib-Azar^2*, Christine Crider^2*, Margie Fredericks, MSN, ARNP^5*, Hania Shakalia^5*, Stephanie Louie, RN^5*, David G Maloney, MD, PhD², Christina Poh, MD^2,3, Brian G Till², Stephen D Smith, MD^3,6, Ajay K Gopal, MD^3,7, Chaitra S Ujjani, MD⁷ and Mazyar Shadman, MD, MPH^2,8

¹Fred Hutchinson Cancer Center and University of Washington School of Medicine, Seattle, WA
²Fred Hutchinson Cancer Center, Seattle, WA
³Division of Hematology and Oncology, University of Washington, Seattle, WA
⁴Fred Hutch Cancer Center, Seattle, WA
⁵Fred Hutchinson Cancer Center, Seattle
⁶Fred Hutchinson Cancer Center, University of Washington, Seattle, WA
⁷Clinical Research Division, Fred Hutch Cancer Center; and Division of Oncology, University of Washington, Seattle, WA
⁸Division of Medical Oncology, University of Washington, Seattle, WA

Lindsey E. Roeker, MD¹, Andrew D. Zelenetz, MD, PhD¹, Jae H. Park, MD¹, Andriy Derkach, PhD^2*, Mark Blaine Geyer, MD³, Prioty Islam, MD^1*, Lorenzo Falchi, MD¹, Maria Lia Palomba, MD⁴, Anita Kumar, MD¹, Gilles Salles, MD, PhD⁵, Jennifer Kimberly Lue, MD⁵, Aaron D. Goldberg, MD, PhD⁶, Bita Fakhri, MD, MPH⁷, Catherine C. Coombs, MD⁸, Victoria Falco^1*, Gail Panton^1*, Dianna Tyznar^1*, Dhara Soni^1*, Lauren Nogan^1*, Sonia Lebowitz^1*, Katherine Blesie^1*, Monica Shah, BA^1*, Sarah Court^1*, Christopher E. Jensen^9*, Anthony R. Mato, MD^1* and Meghan C. Thompson, MD¹

¹Memorial Sloan Kettering Cancer Center, New York, NY
²Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY
³Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁴Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁵Lymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁶Memorial Sloan Kettering Cancer Center, New York City, NY
⁷Stanford University School of Medicine, Stanford, CA
⁸University of California Irvine, Irvine, CA
⁹Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC