Xavier Calvo, MD, PhD^1*, David Román, MD^1*, Nieves Garcia Garcia-Gisbert, PhD^2*, Concepción Fernández-Rodriguez, PhD^3*, Marta Salido, PhD^4*, Anna Puiggros, PhD^4*, Blanca Espinet, PhD^4*, Sara Garcia-Avila, MD^5*, Félix López Cadenas, MD^6*, Abora Rial-Villavecchia, MD^7*, Luis Colomo^8*, Lourdes Florensa, MD, PhD^9*, Ana Ferrer, MD, PhD^1* and Leonor Arenillas, MD, PhD^1*

¹Laboratori de Citologia Hematològica, Servei de Patologia, Hospital del Mar, GRETNHE, IMIM, Barcelona, Spain
²Institut Hospital del Mar d'Investigacions Mèdiques, Barcelona, ESP
³Laboratori de Biologia Molecular, Servei de Patologia, Hospital del Mar, IMIM, Barcelona, Spain
⁴Laboratori de Citogenètica, Servei de Patologia, Hospital del Mar, GRETNHE, IMIM, Barcelona, Spain
⁵Hospital del Mar, Barcelona, Spain
⁶Servicio de Hematología, Hospital Del Mar, Barcelona, Spain
⁷Servicio de Medicina Interna, Hospital del Mar, Barcelona, ESP
⁸Pathology Department, Hospital del Mar, Barcelona, Spain
⁹Laboratori de Citologia Hematològica, Servei de Patologia, Hospital del Mar, GRETNHE, IMIM, Barcelona, ESP

Maria Sola, MD^1,2*, Francisco Beas^3,4*, Laura Palomo, PhD^5,6*, Mar Tormo, M.D.⁷, Ana Riera, MD^7*, Nicolas Díaz Varela, MD^8*, Teresa Bernal^8*, Sara García, MD^9*, Concepción Fernández, PhD^9,10*, Nieves Garcia-Gisbert^9,10*, Félix López Cadenas, MD^9*, Barbara Tazon, PhD^5,6*, Adoracion Blanco^5,6*, Sara Garrido Paniagua, MD^5,6*, Ana Pérez González, MD^5,6*, Andres Jerez, MD, PhD^5,6*, Julia Montoro, PhD^2,5*, Olga Salamero, MD^5,6* and David Valcarcel, MD, PhD^5,6

¹Experimental Hematology Unit, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain
²Hematology Department, Vall d’Hebron University Hospital, University Autònoma of Barcelona (UAB), Barcelona, Spain
³Department of Hematology, Vall d'Hebron University Hospital, Barcelona, Spain
⁴Experimental Hematology Unit, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, AL, Spain
⁵Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain
⁶Department of Hematology, Vall d’Hebron University Hospital, Barcelona, Spain
⁷Hospital Clínico Universitario de Valencia, Instituto de Investigación Sanitaria INCLIVA, Valencia, Spain
⁸Hospital Universitario Central de Asturias, Instituto Universitario (IUOPA), Instituto de Investigación del Principado de Asturias (ISPA), Oviedo, Spain
⁹Department of Hematology, Hospital del Mar, Barcelona, Spain
¹⁰IMIM-Hospital del Mar, Barcelona, Spain

Alex Bataller, MD, PhD^1*, Guillermo Montalban-Bravo, MD¹, Alexandre Bazinet, MD^2*, Yesid Alvarado Valero, MD¹, Kelly S. Chien, MD¹, Sangeetha Venugopal, MD, MS³, Jo Ishizawa, MD, PhD¹, Danielle E. Hammond, MD¹, Mahesh Swaminathan, MD¹, Koji Sasaki, MD¹, Ghayas C. Issa⁴, Nicholas J. Short, MD¹, Lucia Masarova, MD¹, Naval Daver, MD¹, Tapan M. Kadia, MD¹, Simona Colla, PhD⁵, Wei Qiao, PhD^6*, Xuelin Huang, PhD^6*, Rashmi Kanagal-Shamanna, MD⁷, Stephany Hendrickson^8*, Farhad Ravandi, MD, MBBS¹, Elias Jabbour⁹, Hagop Kantarjian, MD¹ and Guillermo Garcia-Manero, MD¹⁰

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, MD Anderson Cancer Center, Houston, TX
³University of Miami, Sylvester Cancer Center, Miami, FL
⁴The University of Texas MD Anderson Cancer Center, Houston, TX
⁵MD Anderson Cancer Center, HOUSTON, TX
⁶Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷Department of Hematopathology, The University of Texas M D Anderson Cancer Center, Houston, TX
⁸Leukemia Department, The University of Texas MD Anderson Cancer Center, Houston, TX
⁹University of Texas M.D. Anderson Cancer Ctr., Houston, TX
¹⁰University of Texas MD Anderson Cancer Center, Houston, TX

Ilias Sinanidis, M.D.^1*, Michael Jamie Hochman, MD², Hua-Ling Tsai^2*, Michael P Randall, MD², Brandon Bonilla^2*, Ravi Varadhan^3*, Alexander Joseph Ambinder, MD, MPH⁴, Amy E. DeZern, MD, MHS⁵ and Theodoros Karantanos, MD, PhD²

¹Johns Hopkins University Hospital, Baltimore
²Johns Hopkins University - Sidney Kimmel Cancer Center, Baltimore, MD
³Johns Hopkins, Baltimore, MD
⁴Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD
⁵Sidney Kimmel CCC, Johns Hopkins University, Baltimore, MD

Krzysztof Madry, MD, PhD^1*, Anna Jachalska^2*, Pawel Szwedyk^3*, Oktawia Sosnia^4*, Elzbieta Wiater^5*, Agata Obara^6*, Dorota Krochmalczyk, MD^7*, Anna Kopinska^8*, Małgorzata Gajewska^9*, Anna Kulikowska De Nalecz^10*, Agnieszka Kopacz^11*, Magdalena Olszewska-Szopa^12*, Aleksandra Golos, MD, PhD^13*, Edyta Subocz, MD^14*, Rafal Machowicz, MD, PhD, MSc^15*, Iwona Hus, MD^16*, Alicja Rydzewska-Rosołowska^17*, Anna Wasińska-Krawczyk^18*, Grzegorz Basak, MD, PhD^19* and Andrzej Rydzewski^18*

¹Hematology, Transplantation and Internal Medicine, Medical University, Warsaw, Warsaw, Poland
²Biziel Hospital, Bydgoszcz, Poland
³Department of Hematology, Rydygier Specialistic Hospital, Krakow, POL
⁴Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
⁵Department of Hematology, Specialistic Hospital, Toruń, Poland
⁶Department of Hematology, Holycross Cancer Center, Kielce, Poland
⁷Department of Hematology, Collegium Medicum, Jagiellonian University, Krakow, Poland
⁸Department of Hematology and Bone Marrow Transplantation, Medical University of Silesia, Katowice, Poland
⁹Department of Hematology, Military Institute of Medicine, Warsaw, Poland
¹⁰Department of Hematology, State Hospital, Opole, Poland
¹¹Department of Hematology, Voivodeship Specialistic Hospital in Rzeszów, Rzeszow, POL
¹²Department of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Medical University Wrocław, Wrocław, Poland
¹³Department of Hematology, Medical University of Łodz, Łodz, Poland
¹⁴Warmian-Masurian Cancer Center of the Ministry of the Interior and Administration Hospital, Olsztyn, Poland
¹⁵Medical University of Warsaw, Warsaw, POL
¹⁶The National Institute of Medicine of the Ministry of Interior and Administration, Warszawa, Poland
¹⁷Department of Nephrology and Hypertension with Dialysis Unit, Medical University Białystok, Białystok, Poland
¹⁸Department of Internal Medicine, Nephrology and Transplantation, The National Institute of Medicine of the Ministry of Interior and Administration, Warsaw, Poland
¹⁹Department of Hematology, Transplantation and Internal Medicine, Medical University of Warsaw, Warsaw, Poland

Sandra Castaño-Díez, MD^1,2*, Ines Zugasti^3*, Xavier Calvo, MD, PhD^2,4*, Felicitas Schulz^5*, Alejandro Avendaño Pita^2,6*, Elvira Mora, MD, PhD^2,7*, Jose Francisco Falantes^2,8*, Gemma Azaceta^2,9*, Mariam Ibáñez^2,10*, Tzu Chen^2,11*, Cristina Notario^2,12*, Neus Amer Salas, MD^2,13*, Mònica López-Guerra^14*, Carlos Jimenez-Vicente, MD^15*, Daniel Esteban^16*, Francesca Guijarro, MD^17*, José Ramón Álamo Moreno, MD^18*, Albert Cortés-Bullich, MD^3*, Daniel Munárriz, MD^16*, Víctor Torrecillas-Mayayo^19*, Ana Triguero^16*, Natalia Tovar, MD^18*, Alexandra Martínez-Roca, MD^3*, Beatriz Merchán Muñoz, MD^15*, Esther Carcelero^16*, Ulrich Germing^20*, Beate Betz^21*, María Rozman^2,18*, Leonor Arenillas, MD, PhD^2,4*, Lurdes Zamora, PhD^2,22*, Maria Diez-Campelo, MD, PhD^2,23*, Blanca Xicoy, MD^2,24*, Jordi Esteve, MD, PhD¹⁵ and Marina Díaz-Beyá, MD, PhD^1,2*

¹Hematology Department, Hospital Clínic Barcelona, Barcelona, Spain
²Grupo Español de Síndromes Mielodisplásicos (GESMD), Madrid, Spain
³Hematology Department, Hospital Clinic de Barcelona, ICMHO, Barcelona, Spain
⁴Laboratori de Citologia Hematològica, Servei de Patologia, Hospital del Mar, GRETNHE, IMIM, Barcelona, Spain
⁵Dept of Hematology, Oncology and Clinical Immunology, University Clinic, Heinrich Heine University Düsseldorf, Düsseldorf, DEU
⁶Hospital Universitario de Salamanca, Salamanca, Spain
⁷Department of Hematology, Hospital Universitario y Politécnico La Fe, Valencia, Spain
⁸Complejo Hospitalario Virgen del Rocío, Sevilla, ESP
⁹Hospital Clínico Universitario Lozano Blesa de Zaragoza, Zaragoza, ESP
¹⁰Hospital General Universitario de Valencia, VALENCIA, ESP
¹¹Hospital General Universitario Morales Meseguer, Murcia, Spain
¹²Hospital Universitario Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain
¹³Hospital Universitario Son Llàtzer, Palma de Mallorca, Spain
¹⁴Hematopathology Section, Pathology Department, Hospital Clínic Barcelona, Barcelona, Spain
¹⁵Hematopoietic Cell Transplantation Unit, Hospital Clínic de Barcelona, ICHMO, Barcelona, Spain
¹⁶Hospital Clínic de Barcelona, Barcelona, Spain
¹⁷Hematopathology Unit, Pathology Department, Hospital Clínic de Barcelona, Barcelona, Spain
¹⁸Hospital Clínic Barcelona, Barcelona, Spain
¹⁹University of Barcelona, Barcelona, Spain
²⁰Department of Hematology, Oncology and Clinical Immunology, Universitatsklinik Dusseldorf, Dusseldorf, Germany
²¹Institute for Human Genetics, Heinrich Heine University Düsseldorf, Düsseldorf, Germany
²²Hematology Department, Institut Català d’Oncologia - Hospital Universitari Germans Trias i Pujol, Institut de Recerca Contra la Leucèmia Josep Carreras, Universitat Autònoma de Barcelona, Badalona, Spain
²³Department of Hematology, Salamanca-IBSAL University Hospital, Salamanca, Spain
²⁴Hematology Service, Hospital Germans Trias I Pujol, Institut Català Oncologia, Josep Carreras Leukemia Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain

Yasmin Abaza, MD¹, Zhuoer Xie, MD, MS², Madelyn Burkart, MD¹, Talha Badar, MD³, Pinkal Desai, MD, MPH⁴, Rory M. Shallis, MD⁵, Anand Ashwin Patel, MD⁶, Adam Cohen-Nowak, MD^1*, Timothy S. Oh, MD^1*, Chelsea Walker, MD^2*, Neela Easwar, MD^4*, Tariq Kewan, MBBChir⁷, Joseph Cannova, MD, PhD, BS⁶, Kirsten Bell-Burdett^1*, Najla H Al Ali, MS^2*, David A Sallman, MD⁸, Gail J. Roboz, MD⁴, Hetty E. Carraway, MD, MBA⁹, Amer M. Zeidan, MBBS, MHS⁷, Mrinal M. Patnaik, MD, MBBS¹⁰, Jessica K. Altman, MD¹ and Rami S. Komrokji, MD²

¹Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL
²Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
³Mayo Clinic, Jacksonville, FL
⁴Weill Cornell Medicine, The New York Presbyterian Hospital, New York, NY
⁵Section of Hematology, Department of Internal Medicine, Yale School of Medicine and Yale Cancer Center, Killingworth, CT
⁶Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL
⁷Section of Hematology, Department of Internal Medicine, Yale School of Medicine and Yale Cancer Center, New Haven, CT
⁸H. Lee Moffitt Cancer Center, Tampa, FL
⁹Department of Hematology and Medical Oncology, Taussig Cancer institute, Leukemia Program, Cleveland Clinic, Cleveland, OH
¹⁰Division of Hematology, Mayo Clinic, Rochester, MN

Waihay J Wong, MD^1,2, Rebecca L. Zon, MD^1,3*, Caleb Ho, M.D.⁴, Olga Pozdnyakova^2*, Donna S. Neuberg, ScD⁵, Elisabeth M Battinelli, MD, PhD³, Marlise R. Luskin, MD, MSCE^3,6, Zuzana Tothova, MD, PhD^6,7, Elizabeth A. Morgan, MD^2*, Christopher James Gibson, MD⁶ and Benjamin L. Ebert, MD, PhD^1,8,9

¹Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
²Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
³Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
⁴Loxo@Lilly, Indianapolis, IN
⁵Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
⁶Dana-Farber Cancer Institute, Boston, MA
⁷Cancer Program, Broad Institute, Cambridge, MA
⁸Howard Hughes Medical Institute, Boston, MA
⁹Department of Medicine, Harvard Medical School, Boston, MA

Farah Fleti^1*, Onyee Chan, MD^2*, Najla H Al Ali, MS^2*, Aref Al-Kali, MD³, Kebede Begna, MD³, James M. Foran, MD⁴, Talha Badar, MD⁵, Nandita Khera, MD⁶, Mithun V Shah, MD, PhD³, Devendra Hiwase, MD, MBBS, PhD, FRACP, FRCPA⁷, Eric Padron, MD², David A Sallman, MD⁸, Animesh D. Pardanani, MBBS, PhD³, Daniel A. Arber, MD⁹, Attilio Orazi, MD^10*, Kaaren K. Reichard, MD¹¹, Rong He, MD¹¹, Rhett Ketterling, MD¹, Naseema Gangat, MBBS³, Rami S. Komrokji, MD² and Ayalew Tefferi, MD³

¹Mayo Clinic, Rochester, MN
²Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
³Division of Hematology, Mayo Clinic, Rochester, MN
⁴Hematology/Oncology, Mayo Clinic, Jacksonville, FL
⁵Mayo Clinic, Jacksonville, FL
⁶Mayo Clinic, Phoenix, AZ
⁷Walter and Eliza Hall Institute of Medical Research, Adelaide, SA, Australia
⁸H. Lee Moffitt Cancer Center, Tampa, FL
⁹University of Chicago, Chicago, IL
¹⁰Texas Tech University Health Sciences Center, El Paso
¹¹Division of Hematopathology, Mayo Clinic, Rochester, MN

Francisco Beas^1*, Maria Sola, MD^2*, Mar Tormo, M.D.³, Ana Riera, MD^3*, Nicolas Diaz Varela, MD^4*, Félix López Cadenas, MD^5*, Nieves Garcia-Gisbert^6*, Sara García, MD^7*, Laura Palomo, PhD^8*, Sandra Novoa Jáuregui, MD^9*, Olga Salamero, MD^10*, Ana Pérez-González, MD^10*, Silvia Saumell, MD, PhD^9*, Barbara Tazon, PhD^11*, Laura Gallur, MD^9*, Gloria Hidalgo-Gómez, PhD^9*, Sara Torres-Esquius, MSc^9*, Francesc Bosch, MD, PhD⁹, Andres Jerez, MD, PhD^11*, Maria Julia Montoro, MD, PhD^9* and David Valcarcel, MD, PhD⁹

¹Experimental Hematology Unit, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, AL, Spain
²Department of Hematology, Vall d’Hebron University Hospital, University Autonoma of Barcelona (UAB), Barcelona, Spain, Barcelona, Spain
³Hospital Clínico Universitario de Valencia, Instituto de Investigación Sanitaria INCLIVA, Valencia, Spain
⁴Santiago Clinic Hospital CHUS, Santiago De Compostela, ESP
⁵Servicio de Hematología, Hospital Del Mar, Barcelona, Spain
⁶IMIM-Hospital del Mar, Barcelona, Spain
⁷Hematology Department, Hospital del Mar, Barcelona, Spain
⁸Department of Hematology, Vall d'Hebron University Hospital, Barcelona, Spain
⁹Department of Hematology, Vall d'Hebron Institute of Oncology, Vall d'Hebron University Hospital, Barcelona, Spain
¹⁰Hematology Department, Vall d'Hebron University Hospital, University Autònoma of Barcelona (UAB), Barcelona, Spain
¹¹Hematology Department, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain

Amer M. Zeidan, MBBS, MHS¹, Pierre Fenaux, MD, PhD², Xia Han, MSc^3*, David A. James, MSc^3*, Kamel Malek, MD MPH^4*, Pedro Marques Ramos, PhD^4*, Yasushi Miyazaki, MD PhD⁵ and Uwe Platzbecker, MD⁶

¹Yale School of Medicine and Yale Cancer Center, Yale University, New Haven, CT
²Department of Hematology, Université de Paris, Saint-Louis Hospital, Paris, France
³Novartis Pharmaceuticals Corporation, East Hanover, NJ
⁴Novartis Pharma AG, Basel, Switzerland
⁵Nagasaki University, Nagasaki, Japan
⁶Department of Hematology, University Hospital of Leipzig, Leipzig, Germany

Alex Bataller, MD, PhD^1*, Georgina Gener-Ricos^2*, Emmanuel Almanza, MD^1*, Samuel Urrutia, MD³, Kelly S. Chien, MD¹, Danielle E. Hammond, MD¹, Koji Sasaki, MD², Courtney D. DiNardo, MD, MSc¹, Farhad Ravandi, MD, MBBS¹, Gautam Borthakur, MD¹, Tapan M. Kadia, MD¹, Rashmi Kanagal-Shamanna, MD⁴, Hagop M. Kantarjian, MD¹, Guillermo Garcia-Manero, MD⁵ and Guillermo Montalban-Bravo, MD¹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Hematopathology, MD Anderson Cancer Center, Houston, TX
⁵The University of Texas MD Anderson Cancer Center, Houston, TX

Guillermo Montalban-Bravo, MD¹, Elias Jabbour², Kelly S. Chien, MD¹, Danielle E. Hammond, MD¹, Nicholas J. Short, MD¹, Farhad Ravandi, MD, MBBS¹, Marina Y. Konopleva¹, Gautam Borthakur, MD¹, Naval Daver, MD¹, Rashmi Kanagal-Shamanna, MD³, Wei Qiao, PhD^4*, Xuelin Huang, PhD^4*, Heather Schneider, BSN, RN^5*, Meghan Anne Meyer, BSN, RN^5*, Hagop M. Kantarjian, MD⁵ and Guillermo Garcia-Manero, MD⁶

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²University of Texas M.D. Anderson Cancer Ctr., Houston, TX
³Hematopathology, MD Anderson Cancer Center, Houston, TX
⁴Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁶The University of Texas MD Anderson Cancer Center, Houston, TX

Shivani Handa, MD¹, Namrata Sonia Chandhok, MD², Sudhamsh Reddy Desai, MD^3*, Asem Berkalieva^4*, Erin Moshier^4*, Douglas Tremblay, MD¹, Lewis R. Silverman, MD¹, Trent Wang, DO, MPH⁵, Uroosa Ibrahim, MD⁶, Aditi Shastri, MD⁷ and Jonathan Feld, MD¹

¹Division of Hematology & Medical Oncology, Tisch Cancer Institute/ Icahn School of Medicine at Mount Sinai, New York, NY
²Division of Hematology, University of Miami Miller School of Medicine/ Sylvester Comprehensive Cancer Center, Miami, FL
³Department of Internal Medicine, Jacobi Medical Center/ Albert Einstein College of Medicine, Bronx, NY
⁴Department of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai, New York, NY
⁵University of Miami Miller School of Medicine/ Sylvester Comprehensive Cancer Center, Miami Springs, FL
⁶Division of Hematology & Medical Oncology, Cellular Therapy and Bone Marrow Transplant, Tisch Cancer Institute/ Icahn School of Medicine at Mount Sinai, New York, NY
⁷Department of Oncology, Montefiore Medical Center/ Albert Einstein College of Medicine, Bronx, NY

Tariq Kewan, MBBChir¹, Jan Philipp Bewersdorf, MD², Ondrej Blaha, PhD^3*, Maximilian Stahl, MD⁴, Najla H Al Ali, MS^5*, Amy E. DeZern, MD, MHS⁶, Mikkael A. Sekeres, MD⁷, Hetty E. Carraway, MD, MBA⁸, Pinkal Desai, MD, MPH⁹, Elizabeth A. Griffiths, MD¹⁰, Eytan M. Stein¹¹, Andrew M. Brunner, MD¹², Maria L Amaya, MD, PhD¹³, Joshua F. Zeidner, MD¹⁴, Michael R. Savona, MD¹⁵, Jessica M. Stempel, MD¹⁶, Namrata Sonia Chandhok, MD¹⁷, Constantine Logothetis, MD¹⁸, Rahul Ramaswamy^19*, Ameera Rose^20*, Gail J. Roboz, MD²¹, Benjamin Rolles, MD²², Eunice S. Wang, MD²³, Amyah C. Harris^24*, Rory M. Shallis, MD²⁵, Zhuoer Xie, MD, MS²⁶, Eric Padron, MD⁵, Jaroslaw P. Maciejewski, M.D., Ph.D., FACP²⁷, David A Sallman, MD²⁸, Matteo Giovanni Della Porta, MD^29*, Rami S. Komrokji, MD⁵ and Amer M. Zeidan, MBBS, MHS¹⁶

¹Section of Hematology, Department of Internal Medicine, Yale School of Medicine and Yale Cancer Center, New Haven, CT
²Memorial Sloan Kettering Cancer Center, New York, NY
³Yale Cancer Center, Yale University, New Haven
⁴Dana Farber Institute, Boston, MA
⁵Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
⁶Sidney Kimmel CCC, Johns Hopkins University, Baltimore, MD
⁷Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
⁸Department of Hematology and Medical Oncology, Taussig Cancer institute, Leukemia Program, Cleveland Clinic, Cleveland, OH
⁹Weill Cornell Medicine, The New York Presbyterian Hospital, New York, NY
¹⁰Roswell Park Comprehensive Cancer Center, Buffalo, NY
¹¹Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
¹²Division of Hematology/Oncology, Dana-Farber Cancer Institute, Boston, MA
¹³Division of Hematology, University of Colorado, Aurora, CO
¹⁴University of North Carolina, Lineberger Comprehensive Cancer Center, Chapel Hill, NC
¹⁵Department of Medicine, Vanderbilt University Medical Center, Nashville, TN
¹⁶Section of Hematology, Department of Internal Medicine, Yale University School of Medicine - Yale Cancer Center, New Haven, CT
¹⁷University of Miami, Miami, FL
¹⁸Washington University, Saint Louis, MO
¹⁹Washington University, Saint Louis
²⁰Cleveland Clinic, Cleveland, OH
²¹Weill Cornell Medicine and The New York Presbyterian Hospital, New York, NY
²²Division of Hematology, Department of Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, MA
²³Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY
²⁴Dana Farber Cancer Institute, Boston, MA
²⁵Section of Hematology, Department of Internal Medicine, Yale School of Medicine and Yale Cancer Center, Killingworth, CT
²⁶H. Lee Moffitt Cancer Institute, Tampa, FL
²⁷Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
²⁸H. Lee Moffitt Cancer Center, Tampa, FL
²⁹Humanitas Clinical and Research Center, IRCCS, Rozzano, Italy

Clifford M Csizmar, MD, PhD¹, Mark Gurney, MB, BCh, BAO^1*, Terra L. Lasho, PhD¹, Rashmi Kanagal-Shamanna, MD², Kelly S. Chien, MD³, Danielle E. Hammond, MD³, Christy M Finke^1*, Abhishek A Mangaonkar, MBBS⁴, Aref Al-Kali, MD⁵, Naseema Gangat, MBBS⁵, Ayalew Tefferi, MD⁵, Hassan Alkhateeb, MD^5*, Guillermo Garcia-Manero, MD³, Guillermo Montalban-Bravo, MD³ and Mrinal M. Patnaik, MD, MBBS¹

¹Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN
²Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Mayo Clinic, Rochester, MN
⁵Division of Hematology, Mayo Clinic, Rochester, MN

David Bared Dukenik, MS, BA^1,2*, Deborah Soong, MD^2*, Frank Scarpa^3*, Julia Anderson^4*, Hua Li, MD, PH.d^2*, Viji Udayakuma^2*, Justin M. Watts, MD⁵, Yazan F. Madanat, MD⁴, Mikkael A. Sekeres, MD⁶, Namrata Sonia Chandhok, MD⁷ and Justin Taylor, MD²

¹Nova Southeastern University, Dr. Kiran C. Patel School of Allopathic Medicine, Miami, FL
²Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL
³Neogenomics Laboratories, Inc., Fort Myers, FL
⁴Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX
⁵Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, MIAMI, FL
⁶Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
⁷Division of Hematology, University of Miami Miller School of Medicine/ Sylvester Comprehensive Cancer Center, Miami, FL

Mithun V Shah, MD, PhD¹, Monika Kutyna, PhD^2,3*, Syed Shah, MBBS^1*, Elizabeth Ngoc Hoa Tran^3*, Anmol Baranwal, MBBS^1*, Dariusz Ladon, PhD^4*, Aref Al-Kali, MD¹, Anna Brown, PhD, BSc^4,5*, Dong Chen, MD, PhD⁶, Patricia Greipp, DO⁶, Kebede Begna, MD¹, Mark R. Litzow, MD¹, William J. Hogan, MD¹, Peter Bardy, MBBS^2*, Sharad Kumar, PhD^5*, David T Yeung, MBBS, PhD, BSc, FRACP, FRCPA^2,3,7, Mrinal M. Patnaik, MD, MBBS¹, James M. Foran, MD⁸, Rong He, MD⁶, Naseema Gangat, MBBS¹, Hamish S Scott, PhD, BSc^4,5, Cecilia Y. Arana Yi, MD⁹, Hassan Alkhateeb, MD^1*, Abhishek A Mangaonkar, MBBS¹, Daniel Thomas, MD, PhD^2,3,7, Christopher N. Hahn, PhD^4,10*, Attilio Orazi, MD^11*, Daniel A. Arber, MD¹², Chung Hoow Kok, PhD, BSc^3,7, Ayalew Tefferi, MD¹ and Devendra Hiwase, MD, MBBS, PhD, FRACP, FRCPA^2,3,7

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Haematology, Central Adelaide Local Health Network (CALHN), Adelaide, SA, Australia
³Blood Cancer, Precision Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia
⁴Genetics and Molecular Pathology, SA Pathology, Adelaide, SA, Australia
⁵Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA, Australia
⁶Division of Hematopathology, Mayo Clinic, Rochester, MN
⁷Adelaide Medical School, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia
⁸Hematology/Oncology, Mayo Clinic, Jacksonville, FL
⁹Hematology/Oncology, Mayo Clinic, Scottsdale, AZ
¹⁰University of South Australia, Adelaide, SA, Australia
¹¹Texas Tech University Health Sciences Center, El Paso
¹²University of Chicago, Chicago, IL

Luca Lanino, MD¹, Anthony M. Hunter, MD^2*, Claudia Sala, PhD^3*, Daniele Dall'Olio, PhD^3*, Lorenzo Dall'Olio, PhD^3*, Lisa Pleyer, MD^4*, Blanca Xicoy, MD^5*, Manja Meggendorfer, PhD⁶, Elisabetta Sauta, PhD^7*, Erica Travaglino, BS^7*, Marie Robin, MD, PhD^8*, Laura Palomo, PhD^9*, David Quintela^10*, Andres Jerez, MD, PhD^11*, Elena Cornejo^12*, Paloma Garcia Martin^12*, Marina Díaz-Beyá, MD, PhD^13*, Alejandro Avendaño Pita^14*, Veronica Roldan^15*, Dolly Viviana Fiallo Suarez^16*, Estefania Cerezo Velasco^17*, Marisa Calabuig^18*, Giulia Rivoli, MD^19*, Massimo Bernardi, MD^20*, Francesco Onida, MD^21*, Lorenza Maria Borin, MD^22*, Francesco Passamonti, MD^23*, Alessia Campagna^7*, Marta Ubezio, MD^7*, Antonio Russo, MD^7*, Gabriele Todisco, MD^7*, Giulia Maggioni, MD^7*, Cristina Astrid Tentori, MD^7*, Filippo Viviani, MD^7*, Alessandro Buizza, MD^7*, Gianluca Asti, MSc^7*, Matteo Zampini, PhD^7*, Armando Santoro, MD^24*, Wolfgang Kern, MD⁶, Uwe Platzbecker, MD²⁵, Francesc Sole, PhD²⁶, Maria Diez-Campelo, MD, PhD^27*, Angela Consagra^28*, Najla H Al Ali, MS^29*, David A Sallman, MD³⁰, Pierre Fenaux, MD, PhD³¹, Raphael Itzykson, M.D. / Ph.D.³¹, Michaela Fontenay, MD, PhD^32*, Amer M. Zeidan, MBBS, MHS³³, Rami S. Komrokji, MD³⁴, Valeria Santini, MD³⁵, Torsten Haferlach, MD, PhD⁶, Ulrich Germing^36*, Saverio D'Amico, MSc^7*, Gastone Castellani, PhD^37*, Eric Solary, MD^38*, Eric Padron, MD³⁴ and Matteo Giovanni Della Porta, MD^7*

¹Humanitas Clinical and Research Center, IRCCS, Rozzano, Milano, Italy
²Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta
³University of Bologna, Bologna, Italy
⁴Salzburg Cancer Research Center, Salzburg, AUT
⁵Hematology Department, Institut Català d’Oncologia, Hospital Universitari Germans Trias i Pujol, Institut de Recerca Contra la Leucèmia Josep Carreras, Universitat Autònoma de Barcelona, Badalona, Barcelona, Spain
⁶MLL Munich Leukemia Laboratory, Munich, Germany
⁷Humanitas Clinical and Research Center, IRCCS, Rozzano, Italy
⁸Hopital Saint Louis, Paris, France
⁹Experimental Hematology Unit,Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain
¹⁰Institut Català d’Oncologia, Badalona, Spain
¹¹Hematology Department, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain
¹²Hospital Clínico San Cecilio, Granada, Spain
¹³Hematology Department, Hospital Clínic Barcelona, Barcelona, Spain
¹⁴Hospital Universitario de Salamanca, Salamanca, Spain
¹⁵Hospital Universitario Cruces, Bilbao, Spain
¹⁶Hospital Dr. Negrin, Las Palmas De Gran Canaria, Spain
¹⁷Consorci Sanitari de Terrassa, Terrassa, Spain
¹⁸Hospital Clínico Universitario de Valencia, Valencia, Spain
¹⁹Hematology and Cellular Therapy Division, IRCCS Ospedale Policlinico San Martino, Genova, Genova, Italy
²⁰Unit of Hematology and Bone Marrow Transplantation, I.R.C.C.S. Ospedale San Raffaele, Milan, Italy
²¹Hematology Unit - ASST Fatebenefratelli-Sacco - University of Milan, Milan, Italy
²²Hematology, Ospedale San Gerardo, Monza, Italy, Monza, Italy
²³Dipartimento di Oncologia ed Ematologia, Università degli Studi di Milano, Policlinico di Milano, Ospedale Maggiore, Fondazione I.R.C.C.S. Ca Granda, Milano, Italy
²⁴Humanitas Cancer Center, Rozzano, Mi, Italy
²⁵University Leipzig Medical Center, Leipzig, Germany
²⁶Myelodysplastic Syndromes Research Group, Josep Carreras Leukaemia Research Institute, ICO-Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain
²⁷University Hospital of Salamanca, Salamanca, Spain
²⁸University of Florence, Florence, Italy
²⁹Moffitt Cancer Center, Tampa
³⁰H. Lee Moffitt Cancer Center, Tampa, FL
³¹Department of Hematology, Université de Paris, Saint-Louis Hospital, Paris, France
³²Laboratory of Hematology, Université Paris Cité and Assistance Publique-Hôpitaux de Paris. Centre, Hôpital Cochin, Paris, France
³³Section of Hematology, Department of Internal Medicine, Yale University School of Medicine - Yale Cancer Center, New Haven, CT
³⁴Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
³⁵MDS Unit, DMSC, AOU Careggi, University of Florence, Firenze, Italy
³⁶Department of Hematology, Oncology and Clinical Immunology, Universitatsklinik Dusseldorf, Dusseldorf, Germany
³⁷Department of Physics and Astronomy (DIFA), Bologna, Italy., Bologna, Italy
³⁸GUSTAVE ROUSSY, Villejuif, Val DE Marne, FRA

Guillermo Garcia-Manero, MD¹, James McCloskey, MD², Bart L. Scott, MD³, Elizabeth A. Griffiths, MD⁴, Bonnie Kiner-Strachan, MD⁵, Gail J. Roboz, MD⁶, Janelle Meyer, MD^7*, Winny Chan, PhD^8*, Beloo Mirakhur, MD, PhD⁸, Yuri Sano, MD, PhD⁸, Aram Oganesian, PhD^8*, Harold N. Keer, MD, PhD⁸ and Michael R. Savona, MD⁹

¹University of Texas MD Anderson Cancer Center, Houston, TX
²John Thuerer Cancer Center, Hackensack Medical Center, Hackensack, NJ
³Fred Hutchinson Cancer Center, Seattle, WA
⁴Roswell Park Comprehensive Cancer Center, Buffalo, NY
⁵Perlmutter Cancer Center, NYU Langone Health, New York, NY
⁶Weill Cornell Medicine and The New York Presbyterian Hospital, New York, NY
⁷Oregon Oncology Specialists, Salem, OR
⁸Astex Pharmaceuticals, Inc., Pleasanton, CA
⁹Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN

Thomas Cluzeau, MD, PhD¹, Marie Sebert, MD, PhD^2*, Michael Loschi, MD, PhD^3*, Lionel Ades, MD, PhD⁴, Sylvain Thepot, MD^5*, Martin Carre, MD^6*, Nicolas Duployez, MD^7*, Rosa Sapena, PhD^8*, Fatiha Chermat^9*, Claude Preudhomme, PharmD, PhD^10*, Pierre Fenaux, MD, PhD¹¹ and Marie Robin, MD^12*

¹Nice University Hospital, Nice, Provence Alpes Cote d'Azur, France
²Hôpital Saint-Louis, Paris, France
³Centre Hospitalier Universitaire de Nice, Nice, France
⁴Hôpital Saint-Louis, Hematology Department, Hopital Saint Louis, Paris, France
⁵Department of Clinical Hematology, Angers University Hospital, ANGERS, NA, France
⁶Clinical Hematology Department, CHU Grenoble Alpes - Université Grenoble Alpes, Grenoble, France
⁷Hematology Laboratory, CHRU Lille, Lille, France
⁸Groupe Francophone des Myelodysplasies, Paris, France, Paris, France
⁹Groupe Francophone des Myelodysplasies, Paris, France
¹⁰Hematology Laboratory, CHU Lille, Lille, France
¹¹Hôpital Saint-Louis, Hematology Department, AP-HP, Paris, France
¹²Hopital Saint-Louis, Paris, France

Guillermo Garcia-Manero, MD¹, Lewis R. Silverman, MD² and Lucy Yan, MD, PhD^3*

¹University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY
³Rigel Pharmaceuticals, Inc., South San Francisco, CA

Douglas Tremblay, MD¹, Alan Shih, MD, PhD¹, Jonathan Feld, MD¹, Erin Moshier^2* and John Mascarenhas, MD^1*

¹Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
²Department of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai, New York, NY

Aref Al-Kali, MD¹, Antoine Saliba, MD¹, Cecilia Y. Arana Yi, MD², James M. Foran, MD³, Yasushi Tanoue, MD, PhD^4*, Maki Yamamoto, MS^5*, Joachim Gullbo, MD, PhD^6,7* and Guillermo Garcia-Manero, MD⁸

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Hematology/Oncology, Mayo Clinic, Scottsdale, AZ
³Hematology/Oncology, Mayo Clinic, Jacksonville, FL
⁴Chordia Therapeutics, Chuo-Ku, Japan
⁵Chordia Thaerapeutics, Chuo-Ku, Japan
⁶Theradex Oncology, Princeton, NJ
⁷Uppsala University, Uppsala, Sweden
⁸University of Texas MD Anderson Cancer Center, Houston, TX

Guillermo Garcia-Manero, MD¹, Melissa Ooi, PhD, FRCPath, MBBChir, MRCP^2,3*, Zhentang Lao^4*, Harinder Gill, MD, MBBS, FRCP, FRCPath⁵, Yasmin Abaza, MD⁶, Maximilian Stahl, MD⁷, Tamanna Haque, MD^8*, Amy E. DeZern, MD, MHS⁹, Peter L. Greenberg, MD¹⁰, Marc Pelletier^11*, Arti Singh^12*, Daniel Carreon^12*, Valerie Beaulieu^11* and Janghee Woo, MD, PhD¹³

¹University of Texas MD Anderson Cancer Center, Houston, TX
²National University Cancer Institute, Singapore, Singapore
³National University Health System, Singapore, Singapore
⁴Department of Hematology, Singapore General Hospital, Singapore, Singapore
⁵Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong
⁶Northwestern Medicine, Chicago, IL
⁷Dana Farber Institute, Boston, MA
⁸Memorial Sloan Kettering Cancer Center, New York, NY
⁹Sidney Kimmel CCC, Johns Hopkins University, Baltimore, MD
¹⁰Stanford Cancer Center, Stanford University, Stanford, CA
¹¹Novartis Institutes for BioMedical Research, Cambridge, MA
¹²Novartis Institutes for BioMedical Research, East Hanover, NJ
¹³Novartis Institutes for BioMedical Research, East Hanover, NJ, USA., Atlanta, GA

Mikkael A. Sekeres, MD¹, Uwe Platzbecker, MD^2*, Rasmus Heje Thomsen, MD, MSc^3*, Sam Wilson, PhD^4*, Anne S. Renteria, MD⁵ and Pierre Fenaux, MD, PhD⁶

¹Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
²University Hospital of Leipzig, Leipzig, Germany
³Novo Nordisk A/S, Søborg, Denmark
⁴Novo Nordisk Inc, Watertown, MA
⁵Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC
⁶Department of Hematology, Université de Paris, Saint-Louis Hospital, Paris, France

Rory M. Shallis, MD¹, Ondrej Blaha, PhD^2*, Stephanie Halene, MD³, Lourdes Mendez, MD^4*, Nikolai A. Podoltsev, MD, PhD⁵, Anne Caldwell, RN^6*, Jan Philipp Bewersdorf, MD⁷, Richard F. Little, MD, MPH⁸, Richard Piekarz, MD, PhD^9*, Mrinal M. Patnaik, MD, MBBS¹⁰, Steven D. Gore, MD¹¹ and Amer M. Zeidan, MBBS, MHS¹²

¹Section of Hematology, Department of Internal Medicine, Yale School of Medicine and Yale Cancer Center, Killingworth, CT
²School of Public Health, Department of Biostatistics, Yale University, New Haven
³Department of Internal Medicine, Section of Hematology, Yale University School of Medicine and Yale Cancer Center, New Haven, CT
⁴Section of Hematology, Department of Internal Medicine, Yale School of Medicine - Yale Cancer Center, New Haven, CT
⁵Associate Professor of Medicine, Department of Hematology, Yale School of Medicine, New Haven, CT
⁶Section of Hematology, Department of Internal Medicine, Yale School of Medicine and Yale Cancer Center, New Haven, CT
⁷Memorial Sloan Kettering Cancer Center, New York, NY
⁸Division of Cancer Prevention, National Cancer Institute, Washington, DC
⁹Division of Cancer Research, National Cancer Institute, Rockville, MD
¹⁰Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN
¹¹Division of Cancer Prevention, National Cancer Institute, Rockville, MD
¹²Section of Hematology, Department of Internal Medicine, Yale University School of Medicine - Yale Cancer Center, New Haven, CT

Giulia Petrone, MD, MBBS¹, Eytan M. Stein² and Kelly L. Bolton, MD³

¹Washington University in St. Louis, Department of Medicine, Division of Hematology and Oncology, Saint Louis, MO
²Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
³Department of Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University School of Medicine, Saint Louis, MO, Washington University In St Louis, St Louis, MO