-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

614. Acute Lymphoblastic Leukemia: Therapy, excluding Transplantation: Poster II

Program: Oral and Poster Abstracts
Type: Poster
Hematology Disease Topics & Pathways:
Adult, ALL, antibodies, apoptosis, Biological, CRS, Leukemia, Diseases, neurotoxicity, Non-Biological, CAR-Ts, Combinations, Therapies, Adverse Events, chemotherapy, Pediatric, B-Cell Lymphoma, Biological Processes, Hemoglobinopathies, immunotherapy, Lymphoid Malignancies, Study Population, Clinically relevant, pharmacology, immune mechanism, pathways, signal transduction
Sunday, December 6, 2020: 7:00 AM-3:30 PM

Hind Rafei, MD1, Hagop M. Kantarjian, MD2, Koji Sasaki, MD3, Nicholas J. Short, MD4, Farhad Ravandi, MBBS5, Xuelin Huang, PhD6*, Joseph D. Khoury, MD7, Sa A Wang, MD8*, Jeffrey L. Jorgensen, MD, PhD8*, Issa F. Khouri, MD9, Partow Kebriaei, MD9, Nitin Jain, MD10, Bouthaina S. Dabaja, MD11*, Yesid Alvarado, MD3, Tapan M. Kadia, MD12, Shilpa Paul, PharmD13*, Serena Chew, PharmD13*, Guillermo Garcia-Manero, MD4, Jan A. Burger, MD, PhD4, Courtney D. DiNardo, MD, MSc14, Naval Daver, MD15, Guillermo Montalban-Bravo, MD4*, Musa Yilmaz, MD3, Maro Ohanian, DO4*, Maria Khouri4*, Philip A. Thompson, MB, MS16, Jovitta Jacob4*, Meagan Rostykus, RN4*, Rebecca Garris, MSc4*, Marina Konopleva, MD, PhD17, Susan M. O'Brien, MD18 and Elias Jabbour, MD4

1MD Anderson Cancer Center, Houston, TX
2Department of Leukemia, Professor and Chairman, Department of Leukemia, Samsung Distinguished University Chair in Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
3Department of Leukemia, MD Anderson Cancer Center, Houston, TX
4Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
5Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX
6Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
7Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX
8Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
9Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
10Associate Professor of Medicine Department of Leukemia The University of Texas MD Anderson Cancer Center, Houston, TX
11Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
12Department of Leukemia, M.D. Anderson Cancer Center, Houston, TX
13Department of Pharmacy, The University of Texas MD Anderson Cancer Center, Houston, TX
14Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
15Department of Leukemia, The University of Texas, M.D. Anderson Cancer Center, Houston, TX
16The University of Texas MD Anderson Cancer Center, Houston, TX
17Department of Leukemia, University of Texas, MD Anderson Cancer Center, Houston, TX
18UCI Cancer Center, Orange, CA

Xavier Thomas, MD, PhD1, Anita W Rijneveld, MD, PhD2*, Nicola Fracchiolla, MD3*, Cyril Šálek, MD4*, Alexandros Spyridonidis, MD, PhD5*, Sabina Chiaretti, MD, PhD6, Naufil Alam, PhD7*, Isabella Pezzani Grueter, PharmD8*, Abeera Mohammad, MSc9*, William Kormany, MD10*, Georg Kreuzbauer, MD8* and Alessandro Rambaldi, MD11

1Department of Hematology, Hospices Civils de Lyon, Lyon-Sud Hospital, Pierre-Bénite, Lyon, France
2Department of Hematology, Erasmus University Medical Center, Rotterdam, Netherlands
3UOC Oncoematologia, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Di, Milan, ITA
4Institute of Hematology and Blood Transfusion, Prague, Czech Republic
5General University Hospital of Patra, PATRA, Greece
6Department of Translational and Precision Medicine, Division of Hematology, Rome, Italy
7Center for Observational Research, Amgen Ltd, Uxbridge, United Kingdom
8Amgen (Europe) GmbH, Rotkreuz, Switzerland
9Global Biostatistical Science, Amgen Ltd, Uxbridge, United Kingdom
10Global Patient Safety, Amgen Inc, Thousand Oaks, CA
11Department of Oncology-Hematology, University of Milan and Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy

Hind Rafei, MD1, Hagop M. Kantarjian, MD2,3, Koji Sasaki, MD4, Nicholas J. Short, MD2, Farhad Ravandi, MBBS5, Xuelin Huang, PhD6*, Joseph D. Khoury, MD7, Sa A Wang, MD8,9*, Jeffrey L. Jorgensen, MD, PhD9*, Issa F. Khouri, MD10, Partow Kebriaei, MD10, Richard E. Champlin, MD10, Nitin Jain, MD11, Bouthaina S. Dabaja, MD12*, Ghayas C. Issa, MD13, Naveen Pemmaraju, MD2, Tapan M. Kadia, MD14, Shilpa Paul, PharmD15*, Nadya Jammal, PharmD15*, Guillermo Garcia-Manero, MD2, William G. Wierda, MD, PhD16, Courtney D. DiNardo, MD, MSc17, Naval Daver, MD18, Guillermo Montalban-Bravo, MD2*, Rita Khouri19*, Patrice Nasnas, MD2*, Philip A. Thompson, MB, MS20, Jovitta Jacob2*, Meagan Rostykus, RN2*, Rebecca Garris, MSc2*, Marina Konopleva, MD, PhD21, Susan M. O'Brien, MD22 and Elias Jabbour, MD2

1MD Anderson Cancer Center, Houston, TX
2Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
3Department of Leukemia, Professor and Chairman, Department of Leukemia, Samsung Distinguished University Chair in Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
4Department of Leukemia, MD Anderson Cancer Center, Houston, TX
5Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX
6Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
7Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX
8University of Texas MD Anderson Cancer Center, Department of Hematopathology, Houston, TX
9Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
10Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
11Associate Professor of Medicine Department of Leukemia The University of Texas MD Anderson Cancer Center, Houston, TX
12Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
13Department of Leukemia, Universit Y of Texas At Houston, Houston, TX
14Department of Leukemia, M.D. Anderson Cancer Center, Houston, TX
15Department of Pharmacy, The University of Texas MD Anderson Cancer Center, Houston, TX
16Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
17Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
18Department of Leukemia, The University of Texas, M.D. Anderson Cancer Center, Houston, TX
19University of Texas MD Anderson Cancer Center, Department of Leukemia, Houston, TX
20The University of Texas MD Anderson Cancer Center, Houston, TX
21Department of Leukemia, University of Texas, MD Anderson Cancer Center, Houston, TX
22UCI Cancer Center, Orange, CA

Philip C. Amrein, MD1, Karen K. Ballen, MD2, Kristen E. Stevenson, MS3*, Traci M. Blonquist, MS4*, Andrew M. Brunner5*, Gabriela S. Hobbs, MD6, Hanno R. Hock, MD, PhD7*, Steven L. McAfee, MD8*, Jenna A. Moran, NP6*, Meghan Bergeron, NP6*, Julia E. Foster, NP6*, Christina Bertoli, NP6*, Kristin McGregor6*, Molly Macrae6*, Meghan Burke6*, Tanya T. Behnan, BS6*, Tina T. Som, RN6*, Aura Y. Ramos, RN6*, Megan K. Vartanian, RN6*, Jennifer Lombardi Story6*, Christine Connolly6*, Timothy A. Graubert, MD9, Donna S. Neuberg, ScD3 and Amir T. Fathi10

1Leukemia Center/MGH Cancer Center, Massachusetts General Hospital, Belmont, MA
2Division of Hematology/Oncology, University of Virginia Health Center, Charlottesville, VA
3Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
4Data Science, Dana-Farber Cancer Institute, Boston, MA
5Center for Leukemia, Massachusetts General Hospital, Boston, MA
6Leukemia Center, Massachusetts General Hospital, Boston, MA
7Leukemia Center, Massachusetts General Hospital / Harvard Medical School, Boston, MA
8Massachusetts General Hospital, Blood and Marrow Transplant Program, Boston, MA
9Leukemia Center, Massachussets General Hospital, Charlestown, MA
10Leukemia Center, Massachusetts General Hospital, Center for Leukemia, Cambridge, MA

Jenna Rossoff, MD1, Christina Baggott, RN, PhD2*, Snehit Prabhu, PhD2*, Holly Pacenta, MD3, Christine L Phillips, MD4,5, Heather Stefanski, MD, PhD6, Julie-An Talano, MD7, Amy Moskop, MD7, Steven P. Margossian, MD, PhD8, Michael R Verneris, MD9, Gary Douglas Myers, MD10*, Nicole Karras, MD11*, Patrick A. Brown, MD12, Muna Qayed, MD, MSc13, Michelle Hermiston, MD, PhD14, Prakash Satwani, MD15*, Christa Krupski, DO, MPH16*, Amy Keating, MD17*, Rachel Wilcox18*, Cara A Rabik, MD, PhD19,20, Vanessa Fabrizio, MD21,22, Michael Kunicki23*, Vasant Chinnabhandar, MD6*, A. Yasemin Goksenin, MD, PhD, MA, MPH24*, Kevin J. Curran, MD22,25, Crystal L. Mackall, MD26, Theodore W. Laetsch, MD27 and Liora M. Schultz, MD28

1Division of Pediatric Hematology/Oncology/Stem Cell Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
2Stanford University School of Medicine, Stanford, CA
3Cook Children's Medical Center, Fort Worth, TX
4Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
5University of Cincinnati College of Medicine, Cincinnati, OH
6Department of Pediatrics, Division of Pediatric Blood and Marrow Transplantation, University of Minnesota Medical School, Minneapolis, MN
7Medical College of Wisconsin, Milwaukee, WI
8Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA
9University of Colorado, Anschutz Medical Campus, Colorado Children’s Hospital, Aurora, CO
10Children's Mercy Hospital, Kansas City, MO
11Department of Pediatrics, City of Hope National Medical Center, Duarte, CA
12The Johns Hopkins Hospital, Baltimore, MD
13Pediatric Blood and Marrow Transplantation Program, Aflac Cancer and Blood Disorders Center, Emory University and Children’s Healthcare of Atlanta, Atlanta, GA
14University, San Francisco, CA
15Division of Pediatric Hematology, Oncology, and Stem Cell Transplant, Department of Pediatrics, Columbia University Medical Center, New York, NY
16Department of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
17University of Colorado, Anschutz Medical Campus Colorado Children’s Hospital, Aurora, CO
18Childern's Mercy Hospital, Kansas
19Pediatric Oncology, Bloomberg Children's Center, Baltimore, MD
20The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD
21Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY
22Department of Pediatrics, Weill Cornell Medical College, New York, NY
23Stanford University School of Medicine, Department of Pediatrics, Division of Hematology and Oncology, Palo Alto, CA
24UCSF Benioff Children’s Hospital, San Francisco, CA
25Department of Pediatrics, BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY
26Department of Pediatrics, Division of Hematology and Oncology, Stanford University, Stanford, CA
27Department of Pediatrics and Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX
28Department of Pediatrics, Division of Hematology and Oncology, Stanford University School of Medicine, Palo Alto, CA

Wei Cui1*, Xinyue Zhang2*, Haiping Dai3*, Qingya Cui1*, Baoquan Song4*, Depei Wu, MD, PhD5, Xiaowen Tang, MD, PhD1*, Jia Yin4* and Zheng Li2*

1National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China
2National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China 215006., Soochow, Jiangsu, China
3Department of Hematology, The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, Suzhou, China
4Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China
5The First Affiliated Hosp. of Soochow University, Suzhou, Jiangsu, China

Nora Zieger1,2*, Alyssa Nicholls1,2*, Jan Wulf1,2*, Gerulf Hänel1,2*, Maryam Kazerani Pasikhani1,2*, Veit Buecklein, MD1,2*, Bettina Brauchle1,2*, Anetta Marcinek1,2*, Daniel Nixdorf1,2*, Lisa Rohrbacher1,2*, Michaela Scheurer1,2*, Roman Kischel, MD3*, Karsten Spiekermann, MD2,4,5, Oliver Weigert, MD2,4, Sebastian Theurich, MD2*, Michael von Bergwelt, MD, PhD2* and Marion Subklewe, MD1,2,5

1Laboratory for Translational Cancer Immunology, Gene Center, LMU Munich, Munich, Germany
2Department of Medicine III, University Hospital, LMU Munich, Munich, Germany
3Amgen Research (Munich) GmbH, Munich, Germany
4Experimental Leukemia and Lymphoma Research (ELLF), University Hospital, LMU Munich, Munich, Germany
5German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany

Hind Rafei, MD1, Hagop M. Kantarjian, MD2, Koji Sasaki, MD3, Nicholas J. Short, MD4, Farhad Ravandi, MBBS5, Xuelin Huang, PhD6*, Joseph D. Khoury, MD7, Sa A Wang, MD8*, Jeffrey L. Jorgensen, MD, PhD8*, C. Cameron Yin, MD, PhD8, Issa F. Khouri, MD9, Partow Kebriaei, MD9, Nitin Jain, MD10, Koichi Takahashi, MD, PhD11, Bouthaina S. Dabaja, MD12*, Srdan Verstovsek, MD, PhD4, Tapan M. Kadia, MD13, Shilpa Paul, PharmD14*, Caitlin R. Rausch, PharmD15*, Guillermo Garcia-Manero, MD4, William G. Wierda, MD, PhD16, Courtney D. DiNardo, MD, MSc17, Naval Daver, MD18, Guillermo Montalban-Bravo, MD1*, Musa Yilmaz, MD3, Patrice Nasnas, MD4*, Rita Khouri4*, Monica Kwari, BSN4, Jovitta Jacob4*, Meagan Rostykus, RN4*, Rebecca Garris, MSc4*, Marina Konopleva, MD, PhD19, Susan M. O'Brien, MD20 and Elias Jabbour, MD4

1MD Anderson Cancer Center, Houston, TX
2Department of Leukemia, Professor and Chairman, Department of Leukemia, Samsung Distinguished University Chair in Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
3Department of Leukemia, MD Anderson Cancer Center, Houston, TX
4Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
5Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX
6Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
7Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX
8Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
9Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
10Associate Professor of Medicine Department of Leukemia The University of Texas MD Anderson Cancer Center, Houston, TX
11Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
12Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
13Department of Leukemia, M.D. Anderson Cancer Center, Houston, TX
14Department of Pharmacy, The University of Texas MD Anderson Cancer Center, Houston, TX
15Pharmacy, MD Anderson Cancer Center, Houston, TX
16Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
17Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
18Department of Leukemia, The University of Texas, M.D. Anderson Cancer Center, Houston, TX
19Department of Leukemia, University of Texas, MD Anderson Cancer Center, Houston, TX
20UCI Cancer Center, Orange, CA

Iris Appelmann, MD1*, Azam Salimi1*, Michael Huber, PhD2*, Mirle Schemionek, PhD3*, Margherita Vieri, PhD4*, Tim H Brümmendorf, MD5, John B. Patterson6* and Behzad Kharabi Masouleh, MD7

1Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany
2Institute of Biochemistry and Molecular Immunology, RWTH Aachen University, Aachen, Germany
3Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, RWTH Aachen University, Aachen, Germany
4Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Medical Faculty, University Hospital Aachen, Aachen, Germany
5Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, RWTH Aachen University, Aachen, Germany
6Orinove Inc., Newbury Park, CA
7Kite Pharma, Santa Monica

Wenyi Lu, MD1*, Yunxiong Wei2*, Yaqing Cao1*, Xia Xiao, MD1*, Qing Li1*, Hairong Lyu1*, Yili Jiang1*, Huan Zhang1*, Jia Wang1*, Xin Li1*, Yanyu Jiang1*, Meng Juanxia1*, Yuan Ting1*, Haibo Zhu1*, Xiaoyuan He3*, Xin Jin3*, Rui Sun1*, Tao Sui1*, Kaiqi Liu4* and Mingfeng Zhao, MD, PhD1

1Department of Hematology, Tianjin First Central Hospital, Tianjin, China
2Department of Hematology, Tianjin First Center Hospital, Tianjin, China
3School of Medicine,Nankai University,China, Tianjin, China
4State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Qiuling Chen, MS1,2*, Yuelong Jiang, MS2*, Qinwei Chen, MD, PhD2*, Long Liu, MD, PhD2* and Bing Xu, MD, PhD1,2*

1Department of Hematology, The School of Clinical Medicine, Fujian Medical University, Fuzhou, China
2Department of Hematology, The First Affiliated Hospital of Xiamen University and Institute of Hematology, School of Medicine, Xiamen University, Xiamen, China

*signifies non-member of ASH