Michael R. Savona, MD¹, James K. McCloskey, MD², Elizabeth A. Griffiths, MD³, Karen W.L. Yee, MD⁴, Aref Al-Kali, MD⁵, Amer M. Zeidan, MBBS, MHS⁶, H. Joachim Deeg, MD⁷, Prapti Patel, MD⁸, Mitchell Sabloff, MSc, MD, FRCPC⁹, Mary-Margaret Keating, MD, FRCPC¹⁰, Kim-Hien Dao, DO, PhD¹¹, Nancy Zhu, MD^12*, Nashat Gabrail, MD^13*, Salman Fazal, MD¹⁴, Joseph Maly, MD¹⁵, Olatoyosi Odenike, MD¹⁶, Hagop M. Kantarjian, MD¹⁷, Amy E. DeZern, MD¹⁸, Casey L. O'Connell, MD¹⁹, Gail J. Roboz, MD²⁰, Lambert Busque, MD²¹, Richard A. Wells, MD, DPhil^22*, Harshad Amin, MD^23*, Jasleen K. Randhawa, MD²⁴, Brian Leber, MD²⁵, Yong Hao, MD, PhD^26*, Harold N. Keer, MD, PhD²⁶, Mohammad Azab, MD²⁶ and Guillermo Garcia-Manero, MD¹⁷

¹Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN
²John Theurer Cancer Center at Hackensack Meridian Health, Hackensack, NJ
³Roswell Park Comprehensive Cancer Center, Buffalo, NY
⁴Princess Margaret Cancer Centre, Toronto, Canada
⁵Mayo Clinic, Rochester, MN
⁶Yale University and Yale Cancer Center, New Haven, CT
⁷Fred Hutchinson Cancer Research Center, Seattle, WA
⁸University of Texas Southwestern Medical Center, Dallas, TX
⁹Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada
¹⁰Queen Elizabeth II Health Sciences Centre, Halifax, NS, Canada
¹¹Oregon Health & Science University, Portland, OR
¹²University of Alberta, Edmonton, AB, Canada
¹³Gabrail Cancer Center Research, Canton, OH
¹⁴West Penn Hospital, Allegheny Health Network, Pittsburgh, PA
¹⁵Norton Cancer Institute, Louisville, KY
¹⁶University of Chicago, Chicago, IL
¹⁷The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁸Johns Hopkins University Hospital, Baltimore, MD
¹⁹USC Keck School of Medicine, University of Southern California, Los Angeles, CA
²⁰Weill Medical College of Cornell University New York-Presbyterian Hospital, New York, NY
²¹Research Center, Maisonneuve-Rosemont Hospital, Montreal, QC, Canada
²²Sunnybrook Health Sciences Centre, Toronto, Canada
²³Boca Raton Clinical Research, Boca Raton, FL
²⁴Houston Methodist Cancer Center, Houston
²⁵McMaster University, Hamilton, ON, Canada
²⁶Astex Pharmaceuticals, Inc., Pleasanton, CA

David H. Henry, MD¹, John Glaspy, MD, MPH^2*, Rosemary Anne Harrup^3*, Moshe Mittelman, MD⁴, Amy Zhou, MD⁵, Hetty E. Carraway, MD, MBA⁶, Charles Bradley, Ph.D.⁷, Gopal Saha, MD^7*, Pamela Bartels^7*, Robert Leong^7* and Peony Yu, MD^8*

¹Pennsylvania Hospital, University of Pennsylvania, Philadelphia, PA
²UCLA School of Medicine, Los Angeles
³Royal Hobart Hospital, Tasmania, Australia
⁴Department of Internal Medicine A, Tel Aviv Sourasky Medical Center/Sackler Faculty of Medicine, Tel Aviv, Israel
⁵Washington University School of Medicine, Saint Louis, MO
⁶Department of Hematology and Medical Oncology, Leukemia Program, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH
⁷FibroGen Inc., San Francisco
⁸FibroGen, Inc, San Francisco, CA

Gordon Ruan, MD¹, Caleb J. Smith, MD^2*, Courtney Day^3*, William Harmsen^3*, Abhishek A. Mangaonkar, MBBS⁴, Hassan B. Alkhateeb, MD^4*, Kebede H. Begna, MD⁴, Aref Al-Kali, MD⁴, Mark Litzow, MD⁴, William J Hogan, MB, BCh⁵, Naseema Gangat, MBBS⁴, Animesh Pardanani, MBBS, PhD⁴, Michelle A Elliott, MD⁴, Ayalew Tefferi, MD⁴, Ronald S. Go, MD⁴, Mrinal M. Patnaik, MD, MBBS⁴ and Mithun Vinod Shah, MD, PhD⁴

¹Division of Internal Medicine, Mayo Clinic, Rochester, MN
²Department of Internal Medicine, Mayo Clinic, Rochester, MN
³Biomedical Statistics and Informatics, Mayo Clinic Rochester, Rochester, MN
⁴Division of Hematology, Mayo Clinic, Rochester, MN
⁵Mayo Clinic Rochester, Division of Hematology, Rochester, MN

Igor Stojkov, MSc^1*, Annette Conrads-Frank, PhD^1*, Ursula Rochau, MD, PhD^1*, Marjan Arvandi, PhD^1*, Karin A Koinig, PhD^2*, Michael Schomaker, PhD^1*, Pierre Fenaux, MD, PhD³, David Bowen, MD⁴, Argiris Symeonidis, MD, PhD⁵, Moshe Mittelman, MD^6*, Jaroslav Cermak, MD, PhD^7*, Guillermo F Sanz, MD, PhD⁸, Eva Hellstrom Lindberg, MD, PhD⁹, Luca Malcovati, MD¹⁰, Saskia Langemeijer, MD, PhD^11*, Ulrich Germing^12*, Mette Skov Holm, MD, PhD^13*, Krzysztof Madry, MD, PhD^14*, Agnes Guerci Bresler, MD^15*, Dominic J. Culligan, MD^16*, Ioannis Kotsianidis, MD, PhD^17*, Laurence Sanhes, MD^18*, Juliet Mills, MD^19*, Sibylle Puntscher, PhD^1*, Daniela Schmid, PhD^20*, Corine Van Marrewijk, PhD^11*, Alexandra Smith, PhD^21*, Theo de Witte, MD, PhD^22*, Uwe Siebert, MD, ScD^23* and Reinhard Stauder, MD, MSc²

¹Institute of Public Health, Medical Decision Making and Health Technology Assessment, Department of Public Health, Health Services Research and Health Technology Assessment, UMIT - University for Health Sciences, Medical Informatics and Technology, Hall In Tirol, Austria
²Department of Internal Medicine V (Hematology and Oncology), Innsbruck Medical University, Innsbruck, Austria
³Service d’Hématologie Séniors, Hôpital Saint-Louis, Assistance Publique des Hôpitaux de Paris and Université Paris 7, Paris, France
⁴St. James's Institute of Oncology, Leeds Teaching Hospitals, Leeds, United Kingdom
⁵Department of Medicine, Div. Hematology, University of Patras Medical School, Patras, Greece
⁶Department of Medicine A, Tel Aviv Sourasky (Ichilov) Medical Center and Sackler Medical Faculty, Tel Aviv University, Tel Aviv, Israel
⁷Department of Clinical Hematology, Inst. of Hematology & Blood Transfusion, Praha, Czech Republic
⁸Department of Haematology, Hospital Universitario y Politécnico La Fe, Valencia, Spain
⁹Department of Medicine, Division of Hematology, Karolinska Institutet, Stockholm, Sweden
¹⁰Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Piazzale Golgi 2, Pavia, Italy
¹¹Department of Hematology, Radboud university medical center, Nijmegen, Netherlands
¹²Department of Haematology, Oncology and Clinical Immunology, Universitätsklinik Düsseldorf, Düsseldorf, Germany
¹³Department of Haematology, Aarhus University Hospital, Aarhus, Denmark
¹⁴Department of Haematology, Oncology and Internal Medicine, Warszawa Medical University, Warszawa, Poland
¹⁵Service d'Hématologie Clinique, Centre Hospitalier Universitaire Brabois, Nancy, France
¹⁶Department of Haematology, Aberdeen Royal Infirmary, Aberdeen, United Kingdom
¹⁷Department of Hematology, Democritus University of Thrace, University Hospital of Alexandroupolis, Alexandroupolis, Greece
¹⁸Haematology Department of Perpignan, Saint Jean Hospital, Perpignan, France
¹⁹Leeds Institute for Cancer Studies and Pathology, University of Leeds, Leeds, United Kingdom
²⁰Division for Quantitative Methods in Public Health and Health Services Research, Department of Public Health, Health Services Research and Health Technology Assessment, UMIT - University for Health Sciences, Medical Informatics and Technology, Hall In Tirol, Austria
²¹Epidemiology and Cancer Statistics Group, Department of Heath Sciences, University of York, York, United Kingdom
²²Department of Tumor Immunology - Nijmegen Center for Molecular Life Sciences, Radboud university medical center, Nijmegen, Netherlands
²³UMIT, Dept. of Public Health, Health Services Research & HTA / Harvard Univ., Dept. Health Policy & Management, Institute for Technology Assessment, Hall i. T. (Austria) /, Boston, MA

Heather A. Leitch, MD¹, Hatoon M. Ezzat, MBBS, FRCP^2*, Hayley Merkeley, MD^2*, Rena J. Buckstein, MD, FRCPC³, Nancy Zhu, MD^4*, Thomas J. Nevill, MD^5,6, Harold J. Olney, MD⁷, Karen W.L. Yee, MD⁸, Brian Leber, MD⁹, Mary-Margaret Keating, MD, FRCPC¹⁰, Eve St. Hilaire^11*, Rajat Kumar, MD¹², Robert Delage, MD¹³, Michelle Geddes, MD¹⁴, John M. Storring, MD¹⁵, April Shamy, MD¹⁶, Mohamed Elemary, MD^17* and Richard A. Wells, MD, DPhil^3*

¹St. Paul's Hospital University of British Columbia, Vancouver, BC, Canada
²St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada
³Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
⁴Hematology/Oncology, University of Alberta, Edmonton, AB, Canada
⁵Vancouver General Hospital, Vancouver, BC, Canada
⁶Hematology, Leukemia/BMT Program of BC, BC Cancer, University of British Columbia, Vancouver, BC, Canada
⁷Hematology, Leukemia/BMT Program of British Columbia, Vancouver, BC, Canada
⁸Leukemia Program, Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
⁹McMaster University, Hamilton, ON, Canada
¹⁰Queen Elizabeth II Health Sciences Centre, Halifax, NS, Canada
¹¹Centre d’Oncologie, Dr-Leon-Richard, Moncton, NB, Canada
¹²CancerCare Manitoba, Winnipeg, MB, Canada
¹³CHU de Québec, Hôpital de l'Enfant-Jésus, Centre Universitaire d'Hématologie et d'Oncologie de Québec, Quebec City, QC, Canada
¹⁴Medicine/Hematology, Foothills Medical Centre, Calgary, AB, Canada
¹⁵McGill University Health Centre, Montreal, QC, Canada
¹⁶Sir Mortimer B Davis Hospital, McGill University, Montreal, QC, Canada
¹⁷Saskatoon Cancer Centre, Saskatoon, SK, Canada

Kapil Saxena, MD¹, Marina Konopleva, MD, PhD², Tushar D Bhagat, PhD^3*, Veronica A Guerra, MD², Rita Maduike^4*, Stefano Tiziani, PhD⁵, Gautam Borthakur, MD⁴, Elias Jabbour, MD⁴, Naveen Pemmaraju, MD⁴, Tapan M. Kadia, MD⁴, Nicholas J. Short, MD², Jan A. Burger, MD, PhD², Steven M. Kornblau, MD², Naval Daver, MD², Kiran Naqvi, MD, MPH⁴, Tianyu Cai, PhD^2*, Vinitha Mary Kuruvilla, MSc^2*, Hagop M. Kantarjian, MD⁴, Guillermo Garcia-Manero, MD⁴, Amit Verma, MBBS³ and Courtney D. DiNardo, MD, MSc²

¹Division of Cancer Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, TX
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY
⁴Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX
⁵Department of Nutritional Sciences & Department of Pediatrics, Dell Medical School, The University of Texas at Austin, Austin, TX

Shinpei Harada^1*, Masahiro Onozawa¹, Daisuke Hidaka, MD^1*, Shota Yokoyama^1*, Hajime Senjo, MD¹, Shogo Takahashi, MD^1*, Reiki Ogasawara, MD, PhD^2*, Akio Mori^2*, Shuichi Ota³, Takeshi Kondo, MD, PhD² and Takanori Teshima, MD¹

¹Department of Hematology, Hokkaido University Faculty of Medicine, Sapporo, Japan
²Blood Disorders Center, Aiiku Hospital, Sapporo, Japan
³Department of Hematology, Sapporo Hokuyu Hospital, Sapporo, Japan

John Mascarenhas, MD¹, Rami S. Komrokji, MD², Michele Cavo^3*, Bruno Martino, MD^4*, Dietger Niederwieser, MD, PhD⁵, Andreas Reiter, MD^6*, Bart L. Scott, MD⁷, Maria R. Baer, M.D.⁸, Ronald Hoffman, MD¹, Olatoyosi Odenike, MD⁹, Laurie Sherman, BSN¹⁰, Souria Dougherty, BS, MBA^10*, Tymara Berry, MD^10*, Faye Feller, MD¹⁰, Libo Sun, PhD^10*, Ying Wan, PhD^10*, Aleksandra Rizo, MD, PhD¹⁰, Fei Huang, PhD^10* and Jean-Jacques Kiladjian, MD, PhD¹¹

¹Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
²H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
³Seragnoli Institute of Hematology, University of Bologna, Bologna, Italy
⁴Grande Ospedale Metropolitano-G.O.M. Bianchi-Melacrino-Morelli, Reggio Calabria, Italy
⁵University Hospital Leipzig, Leipzig, Germany
⁶University Hospital Mannheim, Mannheim, Germany
⁷Fred Hutchinson Cancer Research Center, Seattle, WA
⁸Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD
⁹University of Chicago, Chicago, IL
¹⁰Geron Corporation, Parsippany, NJ
¹¹Hopital Saint-Louis, Paris, France

Emma Catherine Difilippo, BS¹, Alejandro Ferrer, PhD^2*, Laura Schultz-Rogers, PhD^3*, Naseema Gangat, MBBS⁴, Shakila P Khan, MD⁵, Aref Al-Kali, MD⁴, Abhishek A. Mangaonkar, MBBS⁴, Animesh Pardanani, MBBS, PhD⁴, Michelle Elliot, MD^6*, Mark Litzow, MD⁴, William J Hogan, MB, BCh⁷, Alexandra P. Wolanskyj, MD^4*, Phuong L. Nguyen, MD⁸, Kaaren K. Reichard, MD^9*, Matthew T Howard, MD^4*, Rebecca L. King, MD⁸, Dong Chen, M.D., Ph.D.⁸, Rong He, MD⁸, David S. Viswanatha, MD⁸, Terra Lasho, PhD⁴, Rajiv K. Pruthi, M.B.B.S⁴, Pavel Pichurin^6*, Teresa Kruisselbrink, MS^6*, Brendan Lanpher, MD^6*, Mark E Wylam, MD^10*, Jennifer L. Oliveira, MD⁹, Dusica Babovic-Vuksanovic, MD^6*, Horatiu Olteanu, MD, PhD^8* and Mrinal M. Patnaik, MD, MBBS⁴

¹Mayo Clinic Alix School of Medicine, Rochester, MN
²Center for Individualized Medicine, Department of Health Sciences Research, Mayo Clinic, Rochester
³Center for Individualized Medicine, Mayo Clinic, Rochester, MN
⁴Division of Hematology, Mayo Clinic, Rochester, MN
⁵Division of Pediatric Hematology, Mayo Clinic, Rochester, MN
⁶Mayo Clinic, Rochester, MN
⁷Mayo Clinic Rochester, Division of Hematology, Rochester, MN
⁸Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
⁹Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
¹⁰Division of Pulmonary & Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN

Rami S. Komrokji, MD¹, Najla Al Ali, M.Sc^1*, Mohammad O Hussaini, MD^2*, David A. Sallman, MD¹, Dana Elise Rollison, PhD^3* and Eric Padron, MD¹

¹Malignant Hematology Department, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
²Department of Hematopathology and Lab Medicine, Moffitt Cancer Center, Tampa, FL
³Moffitt Cancer Center and Research Institute, Tampa, FL

Faezeh Darbaniyan, PhD^1*, Guillermo Montalban Bravo, MD², Yue Wei, PhD², Rashmi Kanagal-Shamanna, MD³, Koji Sasaki, MD⁴, Hui Yang, MD, PhD², Kelly A. Soltysiak, PhD^4*, Kelly S. Chien, MD², Kim-Anh Do, PhD^1* and Guillermo Garcia-Manero, MD⁴

¹Department of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX
⁴Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Anne Sophie Kubasch^1,2,3*, Pierre Peterlin, MD^3,4*, Thomas Cluzeau, MD, PhD^5*, Katharina S. Götze^1,3,6, Katja Sockel, MD^1,7*, Raphael Teipel, MD^7*, Madlen Jentzsch, MD^2*, Sabine Kayser, MD², Habiba Attalah^8*, Fatiha Chermat^8,9*, Silke Gloaguen, Msc^1,3*, Katja Jersemann^10*, Dorothea Schipp^11*, Aristoteles Giagounidis^1,3,12, Stuart McPherson, BSc^13*, Irene Tirado-González^14*, Arjan van de Loosdrecht, MD, PhD^3,15*, Pierre Fenaux, MD, PhD^3,8,16, Uwe Platzbecker, MD^1,3,17, Hind Medyouf^3,14* and Lionel Ades, MD, PhD^3,8,9

¹German MDS Study Group (D-MDS), Leipzig, Germany
²Department of Hematology, Cellular Therapy and Hemostaseology, University Hospital Leipzig, Leipzig, Germany
³The European Myelodysplastic Syndromes Cooperative Group (EMSCO), Leipzig, Germany
⁴CHU de Nantes, Service d’hématologie Clinique, Nantes, France
⁵Service d'Hématologie Clinique, Centre Hospitalier Universitaire de Nice, Nice, France
⁶Klinikum rechts der Isar, Department of Medicine III, Technical University Munich, Munich, Germany
⁷Department of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany
⁸Groupe Francophone des Myélodysplasies (GFM), Paris, France
⁹Service d'Hématologie Séniors, Hôpital Saint-Louis, Paris, France
¹⁰GWT-TUD GmbH, Dresden, Germany
¹¹DS-Statistics, Rosenthal-Bielatal, Germany
¹²Department of Oncology, Hematology and Palliative Care, Marienhospital Düsseldorf, Düsseldorf, Germany
¹³BerGenBio ASA, Bergen, Norway
¹⁴Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany
¹⁵Department of Hematology, Amsterdam University Medical Center, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, Netherlands
¹⁶Hôpital Saint-Louis, Paris, France
¹⁷Hematology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany

Kelly S. Chien, MD¹, Gautam Borthakur, MD², Kiran Naqvi, MD, MPH², Naval Daver, MD², Guillermo Montalban Bravo, MD², Jorge E. Cortes, MD², Courtney D. DiNardo, MD, MSc², Elias Jabbour, MD², Yesid Alvarado, MD², Michael Andreeff, MD, PhD³, Prithviraj Bose, MD³, Nitin Jain, MD², Kimberly Sheppard, BSN, RN^2*, Cheri Klingner-Winton^2*, Sherry A. Pierce, BSN, BA^2*, Xiao Qin Dong^2*, Kelly A. Soltysiak, PhD^2*, Hagop M. Kantarjian, MD² and Guillermo Garcia-Manero, MD²

¹Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Leukemia, The University of Texas, MD Anderson Cancer Center, Houston, TX

Kiyomi Morita, MD, PhD, Kiran Naqvi, MD, MPH, Guillermo Montalban Bravo, MD, Philip A. Thompson, MB, MS, Koichi Takahashi, MD, PhD, Yesid Alvarado, MD, Elias Jabbour, MD, Hagop M. Kantarjian, MD and Guillermo Garcia-Manero, MD

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Caitlin O'Neill, MD¹, Akil Merchant, MD², Parkash S. Gill, MD^3* and Casey L. O'Connell, MD⁴

¹University of Southern California, Jane Anne Nohl Division of Hematology, Keck School of Medicine, Los Angeles, CA
²Cedars-Sinai Medical Center, Los Angeles, CA
³Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA
⁴Jane Anne Nohl Division of Hematology, Keck School of Medicine of the University of Southern California, Los Angeles, CA

Irina Amitai, MD^1,2*, Michelle Geddes, MD^3*, Nancy Zhu, MD^4*, Mary-Margaret Keating, MD, FRCPC⁵, Mitchell Sabloff^6*, Grace Christou, MD⁷, Brian Leber, MD⁸, Dina Khalaf, BSc, MSc, MD⁸, Heather A. Leitch, MD⁹, Eve St-Hilaire, MD^10*, Nicholas Finn, MD¹¹, April Shamy, MD¹², Karen W.L. Yee, MD¹³, John M. Storring, MD¹⁴, Thomas J. Nevill, MD¹⁵, Robert Delage, MD¹⁶, Mohamed Elemary, MD^17*, Versha Banerji, MD¹⁸, Lisa Chodirker, MD^19*, Lee Mozessohn, MD¹⁹, Anne Parmentier, BA^20*, Mohammed Siddiqui^19*, Alexandre Mamedov^20*, Liying Zhang, PhD^21* and Rena J. Buckstein, MD, FRCPC²²

¹Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Canada
²Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
³University of Calgary, Calgary, Canada
⁴Hematology/Oncology, University of Alberta, Edmonton, AB, Canada
⁵Queen Elizabeth II Health Sciences Centre, Halifax, NS, Canada
⁶Hematology/Oncology, University of Ottawa, Ottawa, ON, Canada
⁷Hematology, The Ottawa Hospital General Campus, Ottawa, ON, Canada
⁸Division of Hematology, Juravinski Cancer Centre, McMaster University, Hamilton, ON, Canada
⁹St. Paul's Hospital University of British Columbia, Vancouver, BC, Canada
¹⁰Centre Hospitalier Universitaire Dr. Georges-L.-Dumont, Moncton, NB, Canada
¹¹Dr George-L Dumont Regional Hospital, Moncton, NB, Canada
¹²Sir Mortimer B Davis Hospital, McGill University, Montreal, QC, Canada
¹³Leukemia Program, Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
¹⁴McGill University Health Centre, Montreal, QC, Canada
¹⁵Hematology, Leukemia/BMT Program of BC, BC Cancer, University of British Columbia, Vancouver, BC, Canada
¹⁶CHU de Québec, Hôpital de l'Enfant-Jésus, Centre Universitaire d'Hématologie et d'Oncologie de Québec, Quebec City, QC, Canada
¹⁷Saskatoon Cancer Centre, Saskatoon, SK, Canada
¹⁸Department of Medical Oncology and Hematology, CancerCare Manitoba, Winnipeg, MB, Canada
¹⁹Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
²⁰Odette Cancer Center, Toronto, ON, Canada
²¹Odette Cancer Centre, Toronto, ON, CAN
²²Sunnybrook Odette Cancer Center, Toronto, ON, Canada

Nikolai Yu. Tcvetkov^1*, Elena V. Morozova^2*, Olga S. Epifanovskaya^2*, Elena V. Babenko^2*, Maria V. Barabanshikova^2*, Kirill V. Lepik^2*, Eugene A. Bakin^2*, Julia J. Vlasova^2*, Anna G. Smirnova^2*, Axel R. Zander³ and Ivan S. Moiseev^2*

¹RM Gorbacheva Research Institute, Pavlov University, Saint-Petersburg, Russia
²RM Gorbacheva Research Institute, Pavlov University, St. Petersburg, Russian Federation
³University of Hamburg, Hamburg, Germany

Karolyn A. Oetjen, MD, PhD¹, Diane E. Bender, PhD^2*, Marianna B. Ruzinova, MD PhD^3*, Daniel A.C. Fisher, PhD^4*, Stephen T. Oh, MD^5,6 and Daniel C. Link, MD⁷

¹Division of Oncology, Department of Medicine, Washington University School of Medicine, St Louis, MO
²Bursky Center for Human Immunology & Immunotherapy Programs, Washington University School of Medicine, St Louis, MO
³Department of Pathology & Immunology, Washington University School of Medicine, St Louis, MO
⁴Washington University in St Louis - School of Medicine, St. Louis., MO
⁵Division of Hematology, Washington University School of Medicine, St. Louis, MO
⁶Center For Human Immunology & Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO
⁷Washington University School of Medicine, St Louis, MO

Amer M. Zeidan, MBBS, MHS¹, Jordi Esteve, MD, PhD², Aristoteles Giagounidis³, Hee-Je Kim, M.D., Ph.D.^4*, Yasushi Miyazaki, MD, PhD⁵, Uwe Platzbecker, MD⁶, Andre C. Schuh⁷, Mikkael A. Sekeres⁸, Jörg Westermann^9*, Zhijian Xiao^10*, Kamel Malek^11*, Jeffrey Scott^12*, Julie Niolat^13*, Severine Peyrard^13*, Fei Ma^12*, Flavia Kiertsman^12*, Mario Stegert^11*, Sabine Hertle^11*, Pierre Fenaux, MD, PhD¹⁴ and Valeria Santini¹⁵

¹Yale University and Yale Cancer Center, New Haven, CT
²Hospital Clinic, Barcelona, Spain
³Marien Hospital Düsseldorf, Düsseldorf, Germany
⁴Catholic Hematology Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
⁵Department of Hematology, Nagasaki University Hospital, Nagasaki, Japan
⁶Hematology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany
⁷Princess Margaret Cancer Centre, Toronto, ON, Canada
⁸Cleveland Clinic, Cleveland, OH
⁹Charité-University Medical Center Berlin, Campus Virchow Clinic, Berlin, Germany
¹⁰Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China
¹¹Novartis Pharma AG, Basel, Switzerland
¹²Novartis Pharmaceuticals Corporation, East Hanover, NJ
¹³Novartis Pharma SAS, Rueil-Malmaison, France
¹⁴Hôpital Saint-Louis, Paris, France
¹⁵MDS Unit, Hematology, AOU Careggi, University of Florence, Florence, Italy