Félix López Cadenas, MD^1*, Eva Lumbreras^2*, Blanca Xicoy, MD^3*, Joaquín Sánchez, MD^4*, Rosa Coll, MD^5*, Bohrane Slama, MD^6*, Jose Angel Hernandez-Rivas, MD, PhD^7*, Sylvain Thepot, MD^8*, Teresa Bernal, MD, PhD^9*, Beatriz Arrizabalaga, MD. PhD^10*, Agnès Guerci-Bresler, MD, PhD^11*, Guillermo F Sanz, MD, PhD¹², Joan Bargay, MD^13*, Maria Luz Amigo, MD^14*, Raquel de Paz, MD^15*, Benet Nomdedeu, MD^16*, Aristoteles Giagounidis¹⁷, Uwe Platzbecker, MD¹⁸, Stefan Wickenhauser^19*, Katharina S. Götze²⁰, Ali Arar^21*, Jesus María Hernández Rivas, MD, PhD^22,23, Pierre Fenaux, MD, PhD²⁴, Consuelo Del Cañizo, MD, PhD²⁵ and Maria Diez-Campelo, MD, PhD^26,27*

¹Hematology Department, Hospital Clínico Universitario de Salamanca, Salamanca, SALAMANCA, Spain
²Department of Hematology, Hospital Universitario de Salamanca, Spain, Salamanca, Spain
³Hematology Department, Institut Català d'Oncologia-Hospital Germans Trias i Pujol; Josep Carreras Leukemia Research Institute, Universitat Autònoma de Barcelona, Badalona, Spain
⁴Hematology, University Hospital Reina Sofía, Córdoba, Cordoba, Spain
⁵Hematology Department, ICO - Hospital Doctor Josep Trueta, Girona, Spain
⁶Oncologie Médicale-Hématologie Clinique, Centre Hospitalier Departemental, Avignon, France
⁷University Hospital Infanta Leonor, Madrid, Spain
⁸Clinical Hematology, Angers University Hospital, Angers, France
⁹Hematology Department, Hospital Universitario Central de Asturias, Oviedo, Spain
¹⁰Department of Hematology, Hospital Universitario Cruces, Vizcaya, Spain
¹¹Service d'Hématologie, Centre Hospitalier Universtaire Brabois, Vandoeuvre-lès-Nancy, France
¹²Hematology Department, Hospital Universitario y Politécnico La Fe, Valencia, Spain
¹³Department of Hematology, Son Llatzer University Hospital/ IdISBa, Palma de Mallorca, Spain
¹⁴Hematology and Medical Oncology Department, Hospital Morales Meseguer, IMIB, Murcia, Spain, Murcia, ESP
¹⁵Hematology Department, Hospital Universitario La Paz-Idipaz, Madrid, Spain
¹⁶Hematology Department, Hospital Clinic i Provincial de Barcelona, Barcelona, Spain
¹⁷Department of Oncology, Hematology and Palliative Care, Marienhospital Düsseldorf, Düsseldorf, Germany
¹⁸Hematology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany
¹⁹HôPital Caremeau, Nimes Cedex 9, FRA
²⁰Department of Medicine III, Technical University of Munich, Munich, Germany
²¹Centre Hospitalier Régional d’Orléans, Orleans, FRA
²²University of Salamanca, IBSAL, IBMCC, CSIC, Cancer Research Center, Salamanca, Spain
²³Department of Hematology, University Hospital of Salamanca, Salamanca, Spain
²⁴Hôpital Saint-Louis, Paris, France
²⁵Departamento de Hematología, Hospital Clínico Universitario de Salamanca (CAUSA/IBSAL), Salamanca, Spain
²⁶Hematology Department, Institute of Biomedical Research of Salamanca, University Hospital of Salamanca, Salamanca, Spain
²⁷Grupo Español de Síndromes Mielodisplásicos (GESMD), salamanca, salamanca, Spain

Soo Park, MD¹, Brian M Reilly, BS², Timothy Luger^3*, Dan Zhao^4*, Robert J. Fram, MD⁵, Ajeeta B Dash, PhD^4* and Rafael Bejar, MD, PhD²

¹Moores Cancer Center, University of California San Diego, La Jolla
²Moores Cancer Center, University of California, San Diego, La Jolla, CA
³Arcturus Therapeutics, San Diego, CA
⁴Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, MA
⁵Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Needham, MA

Constance Baer, PhD, Anna Stengel, PhD, Wolfgang Kern, MD, Claudia Haferlach, MD and Torsten Haferlach, MD

MLL Munich Leukemia Laboratory, Munich, Germany

Lin-Pierre Zhao, MD^1,2*, Maxime Boy^3*, Celia Azoulay^2*, Emmanuelle Clappier, PhD, PharmD^4*, Marie Sébert, MD, PhD^5,6*, Ludivine Amable^7*, Jihene Klibi^7*, Kamel Benlagha^8*, Marion Espeli^9,10*, Karl Balabanian^11*, Claude Preudhomme, MD, PhD^12,13, Alice Marceau^14*, Raphael Itzykson, MD, PhD^15,16, Arsène Mékinian^17*, Olivier Fain, M.D^18*, Antoine Toubert^19*, Pierre Fenaux, MD, PhD²⁰, Nicolas Dulphy^10,21* and Lionel Ades, MD, PhD²²

¹Université de Paris, Department of Hematology, Hôpital Saint-Louis, Assistance Publique des Hôpitaux de Paris (AP-HP), Paris, France
²Université de Paris, Saint Louis Research Institute, EMiLy, Inserm U1160, Paris, France
³Université De Paris, IRSL, Emily, Inserm U1160, Paris, FRA
⁴Hematology Laboratory, Saint Louis Hospital, AP-HP, Paris, France
⁵Hématologie clinique, Hôpital Saint-Louis, Paris, France
⁶Hematology Laboratory and INSERM U944, Hopital Saint-Louis, Paris, France
⁷Université De Paris, IRSL, Inserm U1160, Paris, FRA
⁸Université de Paris, Saint Louis Research Institute, Inserm U1160, Paris, France
⁹University of Paris, Saint Louis Research Institue, EMiLy, Inserm U1160, Paris, FRA
¹⁰University of Paris, Saint Louis Research Institue, EMiLy, Inserm U1160, Paris, France
¹¹Université de Paris, Saint Louis Research Institute, EMiLy, Inserm U1160, Paris, FRA
¹²Laboratory of Hematology, Centre Hospitalier Universitaire Lille, Lille, France
¹³UMR-S 1172, INSERM, Lille, France
¹⁴Molecular Biology, CHRU de Lille, Lille, France
¹⁵Hematology Department, Saint-Louis Hospital AP-HP Paris France, Paris, France
¹⁶INSERM U944, Institut Universitaire d'Hématologie, Hopital Saint-Louis, Paris, France
¹⁷APHP, Hôpital Saint Antoine, Service d'Hématologie Clinique et de Thérapie cellulaire, Paris, France
¹⁸Internal Medicine, Saint Antoine University Hospital, université Paris-Sorbonne, Paris, France
¹⁹University of Paris, Saint Louis Research Institute, EMiLy, Inserm U1160, PARIS, FRA
²⁰Service d’Hématologie Séniors, Hôpital Saint-Louis, Assistance Publique des Hôpitaux de Paris and Université Paris 7, Paris, France
²¹Service d'Immunologie et Histocompatibilité / UMRS-1160 INSERM Institut Universitaire d'Hématologie,, Hopital Saint-Louis, Paris, France
²²Institut Univeristaire d'Hematologie, Hopital Saint Louis, Paris, France

Johannes B Goll, MSc^1*, Travis L Jensen, BS^1*, R. Coleman Lindsley, MD, PhD², Rafael Bejar, MD, PhD³, Jason Walker^4*, Robert Fulton, MS^5*, Gregory A. Abel, MD, MPH⁶, Tareq Al Baghdadi, MD^7*, H. Joachim Deeg, MD⁸, Amy E. DeZern, MD⁹, Benjamin L. Ebert, MD, PhD¹⁰, James M. Foran, MD¹¹, Edward J. Gorak, DO, MBA, MS¹², Steven D. Gore, MD¹³, Rami Komrokji, MD¹⁴, Jane Jijun Liu, MD^15*, Jaroslaw P. Maciejewski, MD, PhD^16,17, Eric Padron, MD¹⁸, Wael Saber, MD, MS¹⁹, Daniel Starczynowski, PhD²⁰, Myron Waclawiw, PhD^21*, Steffanie H. Wilson, PhD^1*, Donnie Hebert, PhD^22*, Harrison Reed, MSc^1*, Nancy L. DiFronzo, PhD^21*, Mikkael A. Sekeres, MD, MS²³, Alexandra M. Harrington, MD, MT(ASCP)²⁴, Steven H. Kroft, MD^25*, Ling Zhang, MD^26* and Matthew J. Walter, MD²⁷

¹The Emmes Company, LLC, Rockville, MD
²Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
³Moores Cancer Center, University of California, San Diego, La Jolla, CA
⁴Washington University School of Medicine, St. Louis, MO
⁵McDonnell Genome Institute, Washington University School of Medicine, Saint Louis, MO
⁶Dana-Farber Cancer Institute, Boston, MA
⁷IHA Hematology Oncology Consultants, Ypsilanti, MI
⁸Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
⁹Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD
¹⁰Division of Hematology, Harvard Medical School, Boston, MA
¹¹Division of Hematology and Medical Oncology, Mayo Clinic, Jacksonville, FL
¹²Baptist MD Anderson Cancer Center, Jacksonville, FL
¹³National Institutes of Health, National Cancer Institute, Rockville, MD
¹⁴H. Lee Moffitt Cancer Center, Tampa, FL
¹⁵Illinois Cancer Care, P.C., Peoria, IL
¹⁶Cleveland Clinic Main Campus, Department of Hematology/Oncology, Cleveland, OH
¹⁷Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
¹⁸Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
¹⁹CIBMTR, Medical College of Wisconsin, Milwaukee, WI
²⁰Cincinnati Children's Hospital Medical Center, Cincinnati, OH
²¹National Heart, Lung, and Blood Institute, National Institutes of Health, Division of Blood Diseases & Resources, Bethesda, MD
²²The Emmes Company, LLC, Hamburg, NY
²³Leukemia Program, Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
²⁴Medical College of Wisconsin, Milwaukee, WI
²⁵Department of Pathology, Medical College of Wisconsin, Milwaukee, WI
²⁶Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
²⁷Department of Medicine, Division of Oncology, Washington University In St. Louis, Saint Louis, MO

Nathan Radakovich, BA^1*, Manja Meggendorfer, PhD², Luca Malcovati, MD³, Mikkael A. Sekeres⁴, Jacob Shreve, MD, MS^5*, Cameron Beau Hilton, MD⁶, Yazan Rouphail^7*, Wencke Walter, PhD^8*, Stephan Hutter, PhD^8*, Sudipto Mukherjee, MD, PhD, MPH⁹, Cassandra M. Kerr, MS^10*, Babal K. Jha, PhD^11*, Anna Gallì^12*, Sarah Pozzi^13*, Aaron T. Gerds, MD, MS¹⁴, Cassandra M Kerr, MS^11*, Claudia Haferlach, MD¹⁵, Jaroslaw P. Maciejewski, MD, PhD¹⁰, Torsten Haferlach, MD¹⁶ and Aziz Nazha, MD¹⁷

¹Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
²MLL Munich Leukemia Laboratory, Munich, Bavaria, Germany
³Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Piazzale Golgi 2, Pavia, Italy
⁴Leukemia Program, Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
⁵Department of Internal Medicine, Cleveland Clinic, Cleveland, OH
⁶Department of Internal Medicine, Vanderbilt University, Nashville, TN
⁷Ohio State University, Rocky River, OH
⁸MLL Munich Leukemia Laboratory, Munich, Germany
⁹Leukemia Program, Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
¹⁰Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
¹¹Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH
¹²Department of Hematology Oncology, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy
¹³Centro Cellule Staminali E Terapia Cellulare, Genova, ITA
¹⁴Taussig Cancer Institute, Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
¹⁵MLL Munich Leukemia Laboratory, Inning am Ammersee, Germany
¹⁶MLL Munchner Leukamie Labor Gmbh, Munchen, Germany
¹⁷Leukemia Program, Department of Hematology and Medical Oncology, Taussig Cancer Institute, Quantitative Health Sciences, Avon Lake, OH