Natasha S Anstee, PhD^1,2*, Giovanna Pomilio^1,2*, Mark Levis, MD, PhD^3,4, Sarah MacRaild^1*, Michael Murray, PhD, DSc^4,5*, Tristan Rawling, PhD^6*, Glen A Kennedy, MBBS FRACP FRCPA^4,7*, Andrew Grigg, MBBS, MD, FRACP, FRCPA^4,8*, Anthony Schwarer, MBBS, MD, FRACP, FRCPA^4,9*, Anoop Kumar Enjeti, MBBS, FRCPA, FRACP, PhD, MD, MRCP^4,10, James D'Rozario, MBBS, FRACP, FRCPA^4,11, Paula Marlton, MBBS FRACP FRCPA^4,12, Ian Bilmon, BMBS, FRACP, FRCPA^4,13*, Adam Ivey, BSc, MSc, PhD^1,4*, Doen Ming Ong, MBBS^1,14*, Andrew W Roberts, MBBS^{4,15,16,17,18} and Andrew H Wei, MBBS, PhD^1,2,4

¹The Alfred Hospital, Melbourne, Australia
²Australian Centre for Blood Diseases, Monash University, Melbourne, Australia
³Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD
⁴Australasian Leukaemia and Lymphoma Group (ALLG), Melbourne, Australia
⁵University of Sydney, Sydney, Australia
⁶University of Technology, Sydney, Australia
⁷Department of Haematology, Royal Brisbane and Women's Hospital, Brisbane, Australia
⁸Austin Health and Olivia Newton John Cancer Research Institute, Melbourne, Australia
⁹Box Hill Hospital, Melbourne, Australia
¹⁰Calvary Mater Newcastle Hospital, Sydney, Australia
¹¹The Canberra Hospital, Canberra, Australia
¹²Princess Alexandra Hospital, Brisbane, Australia
¹³Department of Haematology and Bone Marrow Transplantation, Westmead Hospital, Sydney, NSW, Australia
¹⁴Monash University, Melbourne, Australia
¹⁵The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
¹⁶Peter MacCallum Cancer Centre, Melbourne, Australia
¹⁷University of Melbourne, Melbourne, Australia
¹⁸Royal Melbourne Hospital, Melbourne, Australia

Maximilian Stahl, MD^1,2, Andriy Derkach, PhD^3*, Christopher Famulare, MS^4*, Christina Cho, MD^5,6, Sean Devlin, PhD^7*, Noushin Farnoud, PhD^4,8*, Kamal Menghrajani, MD¹, Minal A Patel, MPH^4*, Sheng F Cai, MD, PhD^1,9, Mark B. Geyer, MD^1,10, Andrew Dunbar, MD¹, Zachary D. Epstein-Peterson, MD¹¹, Erin McGovern, BA^4*, Jessica Schulman, BSc^12*, Jacob L Glass, MD, PhD¹, Justin Taylor, MD¹³, Aaron D Viny, MD, MS^1,14, Eytan M. Stein, MD¹, Bartlomiej Getta, FRCPA, FRACP, MBBS^1*, Maria E. Arcila, MD^15,16*, Ross L. Levine, MD^1,4, Juliet Barker, MBBS⁶, Brian C. Shaffer, MD⁶, Esperanza B. Papadopoulos, MD^5,6, Boglarka Gyurkocza, MD⁶, Miguel-Angel Perales, MD^2,6, Omar Abdel-Wahab, MD ^1,14, Elli Papaemmanuil, PhD^17,18, Sergio A. Giralt, MD^2,19, Yanming Zhang, MD²⁰, Mikhail Roshal, MD, PhD¹⁶, Martin S. Tallman, MD ^2,21 and Aaron D Goldberg, MD, PhD²²

¹Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
²Weill Cornell Medical College, New York, NY
³Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY
⁴Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY
⁵Department of Medicine, Weill Cornell Medical College, New York, NY
⁶Department of Medicine, Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁷Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY
⁸Center for Molecular Oncology and Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY
⁹Center for Epigenetic Research, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁰Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY
¹¹Department of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY
¹²Center for Hematologic malignancies, Memorial Sloan Kettering Cancer Center, New York, NY
¹³Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, Miami, FL
¹⁴Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁵Molecular Diagnostics Service, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁶Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁷Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁸5Computational Oncology Service, Department of Epidemiology & Biostatistics, Center for Computational Oncology, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁹Department of Medicine, Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, NY
²⁰Department of Pathology, Memorial Sloan Kettering Cancer Center, Chicago, IL
²¹Memorial Sloan-Kettering Cancer Center, New York, NY
²²Department of Medicine, Leukemia Service, Memorial Sloan-Kettering Cancer Center, New York, NY

Rhonda E. Ries, MA^1*, Timothy Junius Triche Jr., PhD^2,3,4, Jenny L. Smith, MSc, MEd^1*, Amanda R. Leonti, MS^5*, Todd A. Alonzo, PhD^6,7*, Jason E Farrar, MD⁸, Xiaolong Chen, PhD^9*, Yanling Liu, PhD^9*, Timothy Shaw, PhD^10*, Benjamin J. Huang, MD^11*, Yi-Cheng Wang, MS^6*, Robert B. Gerbing, MA^6*, Betsy A Hirsch, PhD^12*, Susana C. Raimondi, PhD¹³, Alan S. Gamis, MD, MPH¹⁴, Richard Aplenc, MD, PhD¹⁵, Jinghui Zhang, PhD^9*, E. Anders Kolb, MD¹⁶, Xiaotu Ma, PhD^9* and Soheil Meshinchi, MD, PhD¹⁷

¹Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
²Van Andel Research Institute, Grand Rapids, MI
³Michigan State University, East Lansing, MI
⁴Keck School of Medicine of University of Southern California, Los Angeles, CA
⁵Clinical Research Division, Fred Hutchinson Cancer Research Center, Mountlake Terrace, WA
⁶Children's Oncology Group, Monrovia, CA
⁷University of Southern California, Los Angeles, CA
⁸University of Arkansas For Medical Sciences, Little Rock, AR
⁹Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN
¹⁰Computational Biology, St. Jude Children's Hospital, Memphis, TN
¹¹Department of Pediatrics, University of California, San Francisco, San Francisco, CA
¹²Division of Molecular Pathology and Genomics, University of Minnesota, Minneapolis, MN
¹³Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN
¹⁴Hematology/Oncology, Children's Mercy Hospitals and Clinics, Kansas City, MO
¹⁵Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA
¹⁶Center for Cancer and Blood Disorders, Nemours Alfred I. duPont Hospital for Children, Wilmington, DE
¹⁷Clinical Research Division, Fred Hutchinson Cancer Rsrch. Ctr., Seattle, WA

Julia K. Herzig, PhD^1*, Frank G. Rücker, MD^1*, Laura K. Schmalbrock, MD^1*, Tamara J. Blätte, PhD^1,2*, Daniela Weber, MSc^1*, Sabrina Skambraks^1*, Silke Kapp-Schwoerer, MD^1*, Andrea Corbacioglu, PhD^1*, Verena I Gaidzik, MD¹, Peter Paschka, MD¹, Ekaterina Panina, MD^1*, Nikolaus Jahn, MD^1*, Anika Schrade, PhD^1*, Frauke Theis, MD^1*, Sibylle Cocciardi, PhD^1*, Walter Fiedler, MD³, Helmut R. Salih⁴, Gerald Wulf, MD^5*, Hans Salwender, MD^6*, Thomas Schroeder^7*, Katharina S. Götze⁸, Thomas Kindler, MD^9*, Michael Luebbert¹⁰, Richard F. Schlenk^11,12, Felicitas Thol¹³, Michael Heuser¹³, Arnold Ganser¹³, Hartmut Döhner¹, Lars Bullinger, MD² and Konstanze Dohner, MD¹

¹Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
²Department of Hematology, Oncology and Tumor Immunology, Charité University Medicine Berlin, Berlin, Germany
³Hubertus Wald University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
⁴Department of Hematology and Oncology, Eberhard Karls University Tübingen, Tübingen, Germany
⁵Department of Hematology and Oncology, University Hospital of Göttingen, Göttingen, Germany
⁶Asklepios Tumorzentrum Hamburg, AK Altona and AK St. Georg, Hamburg, Germany
⁷Department of Hematology, Oncology and Clinical Immunology, University Hospital Düsseldorf, Medical Faculty, Düsseldorf, Germany
⁸Department of Medicine III, Klinikum rechts der Isar, Technische Universität München, Munich, Germany
⁹Department of Hematology, Oncology and Pneumology, University Medical Center, Johannes Gutenberg-University of Mainz, Mainz, Germany
¹⁰Department of Hematology, Oncology, and Stem-Cell Transplantation, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany
¹¹Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany
¹²National Center of Tumor Diseases, NCT-Trial Center, German Cancer Research Center, Heidelberg, Germany
¹³Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany

Abhishek Maiti, MBBS¹, Courtney D. DiNardo, MD, MSc², Sa A Wang, MD^3*, Jeffrey L. Jorgensen, MD, PhD^3*, Tapan M. Kadia, MD⁴, Naval Daver, MD⁵, Nicholas J. Short, MD¹, Musa Yilmaz, MD⁶, Naveen Pemmaraju, MD¹, Gautam Borthakur, MD¹, Prithviraj Bose, MD⁶, Ghayas C. Issa, MD¹, Alessandra Ferrajoli, MD⁷, Elias Jabbour, MD¹, Nitin Jain, MD⁸, Guillermo Garcia-Manero, MD¹, Maro Ohanian, DO^1*, Koichi Takahashi, MD, PhD⁹, Guillermo Montalban-Bravo, MD^1*, Lucia Masarova, MD^1*, Jan A. Burger, MD, PhD¹, Philip A. Thompson, MB, MS¹⁰, Srdan Verstovsek, MD, PhD¹, Koji Sasaki, MD⁶, Michael Andreeff, MD, PhD¹¹, Caitlin R. Rausch, PharmD^12*, Kathryn Montalbano^13*, Sherry A. Pierce, BSN, BA^1*, Hagop M. Kantarjian, MD¹⁴, Marina Konopleva, MD, PhD¹⁵ and Farhad Ravandi, MBBS¹⁶

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
³University of Texas MD Anderson Cancer Center, Department of Hematopathology, Houston, TX
⁴Department of Leukemia, M.D. Anderson Cancer Center, Houston, TX
⁵Department of Leukemia, The University of Texas, M.D. Anderson Cancer Center, Houston, TX
⁶Department of Leukemia, MD Anderson Cancer Center, Houston, TX
⁷Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX
⁸Associate Professor of Medicine Department of Leukemia The University of Texas MD Anderson Cancer Center, Houston, TX
⁹Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁰The University of Texas MD Anderson Cancer Center, Houston, TX
¹¹Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
¹²Pharmacy, MD Anderson Cancer Center, Houston, TX
¹³University of Texas M.D. Anderson Cancer Center, Houston, TX
¹⁴University of Texas MD Anderson Cancer Center, Houston, TX
¹⁵Department of Leukemia, University of Texas, MD Anderson Cancer Center, Houston, TX
¹⁶Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX

Ing Soo Tiong, MBBS, FRACP, FRCPA^1,2,3, Richard Dillon, MA, PhD, MRCP, FRCPath^4,5, Adam Ivey, BSc, MSc, PhD^3*, Chung Hoow Kok, BSc, PhD^6*, James Anton Kuzich, MBBS¹, Nisha Thiagarajah, MBBS^2,7*, Ashish Bajel, FRACP², Nicola Potter, PhD^8*, Matthew Smith, MBBS^9*, Claire Hemmaway^10*, Abin Thomas^11*, Amanda Gilkes^12*, Nigel H. Russell, MD¹³ and Andrew H. Wei¹⁴

¹Austin Health and Olivia Newton John Cancer Research Institute, Melbourne, Australia
²Peter MacCallum Cancer Centre, Melbourne, Australia
³The Alfred Hospital and Monash University, Melbourne, Australia
⁴Guys and St. Thomas Hospital, London, United Kingdom
⁵Department of Medical and Molecular Genetics, King's College, London, United Kingdom
⁶Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, Australia
⁷The Royal Melbourne Hospital, Melbourne, Australia
⁸Cancer Genetics Laboratory, King's College, London, United Kingdom
⁹St Bartholomew's Hospital, London, United Kingdom
¹⁰Auckland City Hospital, Auckland, New Zealand
¹¹Centre for Trials Research, Cardiff University, Cardiff, United Kingdom
¹²Cardiff University, Cardiff, United Kingdom
¹³Guy's Hospital, London, United Kingdom
¹⁴Monash University, Melbourne, Australia