-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

641. CLL: Biology and Pathophysiology, excluding Therapy: Poster II

CLL: Biology and Pathophysiology, excluding Therapy Program: Oral and Poster Abstracts
Type: Poster
Sunday, December 6, 2015: 6:00 PM-8:00 PM
Hall A, Level 2 (Orange County Convention Center)

Jean Fan, BS1*, Lili Wang, MD, PhD2,3*, Angela N Brooks, PhD4,5*, Youzhong Wan, PhD2,3,6*, Donna S Neuberg, ScD7, Laura Z. Rassenti, PhD8, Emanuela M. Ghia, PhD9, Thomas J. Kipps, M.D., PhD.10, Jennifer R. Brown, MD, PhD11,12, Shuqiang Li13*, Kenneth J Livak13*, Matthew M. Meyerson, PhD14*, Peter V. Kharchenko, Ph.D.1* and Catherine J. Wu, MD2,3,11

1Department of Biomedical Informatics, Harvard Medical School, Boston, MA
2Cancer Vaccine Center, Dana-Farber Cancer Institute, Boston, MA
3Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
4Broad Institute, Cambridge, MA
5University of California, Santa Cruz
6School of Life Sciences, Jilin University, Changchun, China
7Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA
8Moores UCSD Cancer Center, CLL Research Consortium, La Jolla, CA
9Moores UCSD Cancer Center, CLL Research Consortium, San Diego, CA
10Moores Cancer Center, University of California, San Diego, La Jolla, CA
11Division of Hematology, Department of Medicine, Brigham and Women’s Hospital, Boston, MA
12Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA
13Fluidigm Corporation, South San Francisco, CA
14Broad Institute of MIT and Harvard, Cambridge, MA

Lijian Yu1,2*, Haesook T. Kim, PhD3*, Siddha Kasar, PhD4*, Parul Benien5*, Wei Du5*, Kevin Hoang2*, Reina Improgo, PhD1,2, Stacey M. Fernandes4*, Josephine L. Klitgaard, MSc, PhD1,4*, Charles Lee, PhD5*, Gady Getz6*, Sunita R Setlur7* and Jennifer R. Brown, MD, PhD1,8

1Department of Medicine, Harvard Medical School, Boston, MA
2Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA
3Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA
4Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
5Department of Pathology, Brigham and Women’s Hospital, Boston, MA
6Broad Institute, Cambridge, MA
7Department of Pathology, Brigham and Women's Hospital, Boston, MA
8Medical Oncology, Dana-Farber Cancer Institute, Boston, MA

Bonnie K. Harrington, DVM1*, Michael Gulrajani, BS2*, Todd Covey2*, Allard Kaptein, PhD3*, Bart Van Lith3*, Raquel Izumi, PhD2, Ahmed Hamdy, MBBCh2, Roger Glenn Ulrich, PhD2*, John C Byrd, MD4, Brian J Lannutti, PhD2* and Amy J. Johnson, PhD4

1College of Veterinary Medicine, The Ohio State University, Columbus, OH
2Acerta Pharma, Redwood City, CA
3Acerta Pharma, Oss, Netherlands
4Division of Hematology, Department of Medicine, The Ohio State University, Columbus, OH

Nisar A. Amin1*, Erlene Kuizon Seymour1, Peter Ulintz1*, Kamlai Saiya-Cork1*, Brian Parkin1*, Kerby Shedden2* and Sami N. Malek3

1University of Michigan, Ann Arbor, MI
2Department of Statistics, University of Michigan, Ann Arbor, MI
3Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI

Marco Benkisser-Petersen1,2*, Maike Buchner3*, Arlette Dörffel1*, Marcus Dühren von Minden4*, Kerstin Leberecht5*, Kathrin Kläsener5*, Rainer Claus, MD6*, Ariane Ott1*, Christine Dierks1*, Hassan Jumaa, PhD4*, Fabio Malavasi7*, Michael Reth5*, Hendrik Veelken, MD, PhD8 and Katja Zirlik, MD9

1Department of Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Freiburg, Germany
2Albert Ludwigs University, Faculty of Biology, Freiburg, Germany
3Technische Universität München, Institute for Clinical Chemistry and Pathobiochemistry, München, Germany
4Department of Immunology, University Medical Center Ulm, Ulm, Germany
5BIOSS Centre for Biological Signalling Studies, University of Freiburg, Freiburg, Germany
6Div. Hematology, Oncology and Stem Cell Transplantation, University of Freiburg Medical Center, Freiburg, Germany
7Department of Medical Sciences, University of Torino Medical School, Torino, Italy
8Department of Hematology, Leiden University Medical Center, Leiden, Netherlands
9Div. Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Freiburg, Germany

Cecelia R Miller, MS1, Amy S. Ruppert, MAS2*, Kevin Coombes, PhD3*, Amy M. Lehman, MAS4*, James S. Blachly, MD2, David M. Lucas, PhD2, Michael R. Grever, MD1, Martin S Tallman, MD5, Ian W. Flinn, MD, PhD6, Laura Z. Rassenti, PhD7, Thomas J. Kipps, MD, PhD7, Deepa Sampath, PhD1, John C Byrd, MD8 and Erin K. Hertlein, PhD1

1Department of Internal Medicine, Division of Hematology, The Ohio State University, Columbus, OH
2Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH
3Department of Biomedical Informatics, The Ohio State University College of Medicine, Columbus, OH
4Center for Biostatistics, Department of Bioinformatics, The Ohio State University, Columbus, OH
5Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
6Sarah Cannon Research Institute, Nashville, TN
7Moores UCSD Cancer Center, CLL Research Consortium, La Jolla, CA
8Division of Hematology, Department of Medicine, The Ohio State University, Columbus, OH

Mohammad Hojjat-Farsangi, Ph.D1, Ali Moshfegh, Ph.D1,2*, Amir Hossein Daneshmanesh, MD, Ph.D1*, Jan Vågberg2*, Byström Styrbjörn2*, Johan Schultz2*, Elisabeth Olsson2*, Charlotta Löfberg2*, Carina Norström2*, Martin Norin2*, Thomas Olin, Ph.D2*, Anders Österborg, MD, PhD3,4 and Håkan Mellstedt, MD, Ph.D1*

1Department of Oncology-Pathology, Cancer Center Karolinska (CCK), Karolinska Institute and Karolinska University Hospital Solna, Stockholm, Sweden
2Kancera AB, Karolinska Institute Science Park, Stockholm, Sweden
3Department of Hematology, Karolinska University Hospital Solna, Stockholm, Sweden
4Department of Hematology, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden

Barbara Kantorova, MSc.1,2*, Jitka Malcikova, Ph.D.1,2*, Kamila Brazdilova, MSc.1,2*, Marek Borsky, MSc.1*, Karla Plevova, Ph.D.1,2*, Jana Smardova, Prof.3*, Martin Trbusek, Ph.D.1,2*, Yvona Brychtova, Ph.D., MD1*, Michael Doubek, Prof., MD1,2, Jiri Mayer1,2 and Sarka Pospisilova, Prof.1,2*

1Department of Internal Medicine - Hematology and Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic
2Central European Institute of Technology, Masaryk University, Brno, Czech Republic
3Department of Pathology, University Hospital Brno, Brno, Czech Republic

Iris de Weerdt1,2*, Sanne Terpstra1,2*, Tom Hofland1,2*, Roeland Lameris, MD3*, Renee C.G. de Bruin3*, Mark-David Levin, MD PhD4, Ester B.M. Remmerswaal, PhD2,5*, Ineke J.M. ten Berge, MD, PhD2,5*, Sanne H. Tonino, MD, PhD1*, Tanja D de Gruijl, PhD3*, Hans van der Vliet, MD, PhD3* and Arnon P. Kater, MD, PhD1

1Department of Hematology, Academic Medical Center, Amsterdam, Netherlands
2Experimental Immunology, Academic Medical Center, Amsterdam, Netherlands
3Department of Medical Oncology, VU University Medical Center, Amsterdam, Netherlands
4Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, Netherlands
5Renal Transplant Unit, Academic Medical Center, Amsterdam, Netherlands

Elisa ten Hacken, PhD1*, Mariela Sivina, PhD1*, Li Ping, PhD1*, Susan O'Brien, MD2, William G. Wierda, MD, PhD1, Alessandra Ferrajoli, MD1, Zeev Estrov, MD1, Michael J. Keating, MD1, Cristina Scielzo3*, Paolo Ghia, MD, PhD3, Federico Caligaris-Cappio, MD3* and Jan A. Burger, MD, PhD1

1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
2University of California - Irvine, Orange, CA
3IRCCS Ospedale San Raffaele and Università Vita-Salute San Raffaele, Milano, Italy

Slinger Erik, PhD*, Arnon P. Kater, MD, PhD, Rachel Thijssen, MSc* and Eric Eldering, PhD*

Departments of Experimental Immunology and Hematology, Lymphoma and Myeloma Center Amsterdam, Academic Medical Center, Amsterdam, Netherlands

Samantha Drennan, PhD1*, Annalisa D'Avola, MSc1*, Yifang Gao, PhD2*, Eleni Chrysostomou, MSc1*, Andrew J Steele, PhD2*, Thorsten Zenz, MD3,4*, Christoph Plass, PhD5*, Peter W Johnson, MD6, Anthony P Williams, PhD, FRCPath2*, Graham Packham, PhD2*, Freda K Stevenson, DPhil2, Christopher C. Oakes, PhD5,7* and Francesco Forconi, MD, DM, PhD, FRCPath1,8*

1Cancer Sciences Unit, Haematological Oncology Group, University of Southampton, Southampton, United Kingdom
2Cancer Sciences Unit, University of Southampton, Southampton, United Kingdom
3NCT/DKFZ Heidelberg, Heidelberg, Germany
4Department of Medicine V, University Hospital Heidelberg, Heidelberg, Germany
5Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany
6Cancer Research UK Clinical Centre, University of Southampton, Southampton, United Kingdom
7The Ohio State University, Columbus, OH
8Department of Haematology, Southampton University Hospital Trust, Southampton, United Kingdom

Doreen te Raa1*, Perry Moerland1*, Alexander Leeksma1*, Ingrid Derks1*, Martin Loden2*, Veronika Navrkalova3*, Martin Trbusek, Ph.D.3*, Dieuwertje Luijks1*, Thorsten Zenz, MD4*, Anna Skowronska, PhD5*, Tatjana Stankovic5, Mels Hoogendoorn, MD, PhD6*, Marinus H. J. van Oers7, Eric Eldering, PhD8* and Arnon P. Kater, MD, PhD8

1Academic Medical Center, Amsterdam, Netherlands
2MRC-Holland, Amsterdam, Netherlands
3Central European Institute of Technology, Masaryk University, Brno, Czech Republic
4Internal Medicine V, University of Heidelberg, Heidelberg, Germany
5School of Cancer Sciences, University of Birmingham, Birmingham, United Kingdom
6Department of Hematology, Medical Center Leeuwarden, Leeuwarden, Netherlands
7Department of Hematology, Academic Medical Center Amsterdam, Amsterdam, Netherlands
8Departments of Experimental Immunology and Hematology, Lymphoma and Myeloma Center Amsterdam, Academic Medical Center, Amsterdam, Netherlands

Paolo Strati, MD1, Joon Uhm1*, Timothy Kaufmann1*, Sameer A. Parikh, MD2, Curtis A. Hanson, MD1, Kari Chaffee1*, Sara Achenbach1*, Timothy G. Call, MD1 and Tait D. Shanafelt, M.D.1

1Mayo Clinic, Rochester, MN
2Division of Hematology, Mayo Clinic, Rochester, MN

Sarah E. M. Herman, PhD1*, Arnau Montraveta, BS2*, Carsten U Niemann, MD, PhD1, Helena Mora-Jensen, PhD1*, Michael Gulrajani, BS3*, Fanny Krantz3*, Bonnie K. Harrington, DVM4*, Todd Covey3*, Brian J Lannutti, PhD3*, Raquel Izumi, PhD3, Roger G Ulrich, PhD3*, John C. Byrd, MD5, Adrian Wiestner, MD, PhD1, Amy J. Johnson, PhD6 and Jennifer A. Woyach, MD5

1Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
2Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
3Acerta Pharma, Redwood City, CA
4College of Veterinary Medicine, The Ohio State University, Columbus, OH
5Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH
6Division of Hematology, Department of Medicine, The Ohio State University, Columbus, OH

Elisavet Chatzilari1*, Panagiotis Baliakas2*, Aliki Xochelli3,4*, Anastasios Maronidis1*, Anna Vardi4,5*, Mattias Mattsson6*, Karin Larsson2*, Vassiliki Douka5*, Michail Iskas, MD7*, George Karavalakis8*, Apostolia Papalexandri5*, Carsten Niemann9, Marco Montillo10*, Achilles Anagnostopoulos5, David Oscier11, Sarka Pospisilova12*, Frederic Davi, MD, PhD13*, Niki Stavroyianni5*, Paolo Ghia14*, Anastasia Hadzidimitriou4*, Richard Rosenquist2, Spiros Nikolopoulos1*, Kostas Stamatopoulos2,4* and Yannis Kompatsiaris1*

1Information Technologies Institute, CERTH, Thessaloniki, Greece
2Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
3Center for Research and Technology Hellas, Thessaloniki, Greece
4Institute of Applied Biosciences, CERTH, Thessaloniki, Greece
5Hematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece
6Uppsala University, Uppsala, Sweden
7Hematology - BMT Unit, George Papanicolaou General Hospital, Thessaloniki, Greece
8Department of Hematology - BMT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece
9Department of Hematology, Rigshospitalet, Copenhagen, Denmark
10Molecular Pathology Unit and Haematology Department, Niguarda Cancer Center, Niguarda Ca’ Granda Hospital, Milan, Italy
11Department of Haematology, Royal Bournemouth Hospital, Bournemouth, United Kingdom
12Central European Institute of Technology, Masaryk University and University Hospital Brno, Brno, Czech Republic
13Department of Biological Hematology, Pitie-Salpetriere Hospital and Pierre et Marie Curie University, Paris, France
14Division of Experimental Oncology and Department of Onco-Hematology, IRCCS San Raffaele Scientific Institute, Milan, Italy

Elisa ten Hacken, PhD1*, Thomas Oellerich, MD2*, Maria Gounari, PhD3*, Julia Hoellenriegel, MS1*, Kuan-Ting Pan, PhD4*, Susan O'Brien, MD5, William Wierda, MD, PhD6, Alessandra Ferrajoli, MD1, Zeev Estrov, MD1, Michael J. Keating, MD1, Henning Urlaub, PhD4,7*, Paolo Ghia, MD, PhD3 and Jan A. Burger, MD, PhD1

1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Hematology/Oncology, Goethe-University Hospital, Frankfurt am Main, Germany
3IRCCS Ospedale San Raffaele and Università Vita-Salute San Raffaele, Milano, Italy
4Bioanalytical Mass Spectrometry Group, Max Plank Institute for Biophysical Chemistry, Goettingen, Germany
5University of California - Irvine, Orange, CA
6Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
7Bioanalytics, Institute for Clinical Chemistry, University Medical Center, Goettingen, Germany

Ana Alicia López-Iglesias1*, Irena Misiewicz-Krzeminska1*, Ignacio Criado2*, Miguel Alcoceba1*, Susana Hernández-García1*, Laura San-Segundo1*, Lorena González-Méndez1*, Montserrat Martín-Sánchez1*, Esperanza M Algarín1*, Teresa Paíno1*, Mercedes Garayoa1*, Norma C Gutierrez1*, Maria-Victoria Mateos1, Marcos González-Díaz1* and Enrique M Ocio1*

1Complejo Asistencial Universitario de Salamanca (IBSAL) y Centro de Investigación del Cáncer (IBMCC-CSIC). Universidad de Salamanca, Salamanca, Spain
2Complejo Asistencial Universitario de Salamanca (IBSAL) y Centro de Investigación del Cáncer (IBMCC-CSIC). Departamento de Medicina y Citometría. Universidad de Salamanca, Salamanca, Spain

Anke Schilhabel1*, Henrik Knecht1*, Anton W. Langerak2*, Jacques J.M. van Dongen2, Michael Kneba1, Jill Ray3*, Elizabeth Punnoose3*, Doris Kim3*, Thomas Haberberger3*, Coen Bernaards3*, Yuda Zhu3*, Sock-Cheng Lewin-Koh3* and Matthias Ritgen1*

1Hematologic Diagnostic Laboratory, University Clinic Schleswig-Holstein Campus Kiel, Kiel, Germany
2Department of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands
3Genentech, Inc., South San Francisco, CA

Valentina Griggio, Ms1*, Candida Vitale, MD1*, Chiara Riganti, MD2*, Joanna Kopecka, PhD2*, Michele Dal Bo3*, Davide Rossi, MD, PhD4, Gabriele Pozzato, MD5, Luca Laurenti, MD6*, Francesco Zallio, MD7*, Monia Marchetti, MD, PhD8*, Marina Ruggeri1*, Paola Omedè1*, Giovanni Del Poeta, Pr, MD9, Valter Gattei, MD3, Gianluca Gaidano, MD, PhD4, Mario Boccadoro, MD1, Massimo Massaia, MD10* and Marta Coscia, MD, PhD1*

1Department of Molecular Biotechnologies and health sciences, Hematology Division, University of Torino, Torino, Italy
2University of Torino, Department of Oncology, Torino, Italy
3Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico, I.R.C.C.S., Aviano, Italy
4Division of Hematology, Department of Translational Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy
5Struttura Complessa Seconda Medicina, Piazza Ospedale 1, Trieste, Italy
6Institute of Hematology, Catholic University of the Sacred Heart, Rome, Italy
7Divisione di Ematologia, Azienda Ospedaliera Santi Antonio e Biagio e Cesare Arrigo, Alessandria, Italy
8Oncology Unit, Ospedale Cardinal Massaia, ASTI, Italy
9Division of Hematology, S. Eugenio Hospital and University of Tor Vergata, Roma, Italy
10SCDU Ematologia e Terapie Cellulari, Azienda Ospedaliera Ordine Mauriziano di Torino, Torino, Italy

Wei Ding, MD, PhD1, Sara J Achenbach2*, Kari G. Chaffee, MS3*, Timothy G. Call, MD1, Sameer A. Parikh, MD1, Susan M. Schwager4*, Jose F. Leis, MD, PhD5, Asher Chanan-Khan, MD6, Deborah A. Bowen, APRN, CNP1*, Michael Conte, PA-C1*, Susan L. Slager, PhD7, Kay Medina, PhD8*, Neil E. Kay, MD1 and Tait D. Shanafelt, M.D.1

1Division of Hematology, Mayo Clinic, Rochester, MN
2Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN
3Biomedical Statistics and Infomatics, Mayo Clinic, Rochester, MN
4Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN
5Department of Hematology, Mayo Clinic, Scottsdale, AZ
6Division of Hematology, Mayo Clinic, Jacksonville, FL
7Department of Health Sciences Research, Mayo Clinic, Rochester, MN
8Division of Immunology, Mayo Clinic, Rochester, MN

Herve Roudot, MD1,2*, Jennifer Martret2*, Fanny Baran-Marszak1,2*, Jean-Francois Collon1*, Abdemalek Dahmani1*, Valerie Lefebvre1*, Xavier Troussard, MD, PhD3, Florence Cymbalista, MD, PhD1,2, Nadine Varin-Blank, PhD2* and Remi Letestu, MD, PhD1,2*

1Hematology Biology, Hopital Avicenne, AP-HP, Bobigny, France
2INSERM U978, Université Paris 13, Sorbonne Paris Cité, Labex “Inflamex”,, Bobigny, France
3Department of Haematology, C.H.U. de CAEN, Caen, France

Vassiliki Mpakou1*, Dikea-Eleni Ioannidou, MD1*, Myrofora Vikentiou1*, Eugenia Konsta1*, Aris Spathis2*, Frieda Kontsioti1*, Christos Kontos3*, Diamantina Vasilatou1*, Anthi Bouchla1*, Kostas Gontopoulos1*, Christoforos Roubakis1*, Georgia Stavroulaki1*, Nikos Papanikolaou1*, Maria Atta1*, Sotiris Papageorgiou1*, Efi Bazani1*, Christina Economopoulou1*, Stela Kokkori1,4*, Elias Kyriakou1,4*, George Dimitriadis1* and Vassiliki Pappa, MD5

1Second Department of Internal Medicine and Research Institute, Attikon University General Hospital, Athens, Greece, Athens, Greece
2Department of Cytopathology, School of Medicine, University General Hospital "ATTIKON", University of Athens, Athens, Greece
3Department of Biochemistry and Molecular Biology, University of Athens, Athens, Greece, Athens, Greece
4Hematology Laboratory, Attikon University General Hospital, Athens, Greece
5Second Department of Internal Medicine and Research Institute, Attikon University General Hospital, Athens, Greece

Jie Wang, MD1*, Jennifer J.D. Morrissette, PhD2*, E. Paul Wileyto, PhD3*, Stephen J. Schuster, MD1, Alexandra Vandegrift, BA4*, Allison Rago, BSN4*, Colleen Dorsey, BSN1*, David Porter, MD1, Daniel J. Landsburg, MD1, Prioty Islam, MD1*, Sunita Dwivedy Nasta, MD1, Jakub Svoboda, MD1, Alison Loren, MD, MS1,5, Scott Weber, BS1*, Edward A. Stadtmauer, MD1 and Anthony Mato, MD1*

1Center for Chronic Lymphocytic Leukemia, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
2Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA
3Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA
4Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
5Abramson Cancer Center of the University of Pennsylvania, Philadelphia, PA

Massimo Gentile, MD1*, Tait D. Shanafelt, M.D.2, Giovanna Cutrona, PhD3*, Stefano Molica, MD4, Giovanni Tripepi, PhD5*, Isabel Alvarez6*, Francesca Romana Mauro, MD, PhD7*, Nicola Di Renzo8*, Francesco Di Raimondo9, Iolanda D. Vincelli10*, Katia Todoerti11*, Serena Matis, PhD12*, Caterina Musolino13*, Sonia Fabris, BSc14*, Ernesto Vigna15*, Luciano Levato, MD16*, Simona Zupo17*, Francesco Angrilli, MD18*, Ugo Consoli, MD19*, Gianluca Festini20*, Giuseppe Longo21*, Agostino Cortelezzi, MD22, Annalisa Arcari23*, Massimo Federico24, Donato Mannina, MD25*, Anna Grazia Recchia, PhD26*, Neil E. Kay, MD27, Manlio Ferrarini, MD28, Antonino Neri, Pr, MD29 and Fortunato Morabito, MD30*

1UOC Ematologia, Ospedale Annunziata, Cosenza, Italy
2Hematology, Mayo Clinic, Rochester, MN
3UO Molecular Patology, IRCCS San Martino-IST, Genoa, Italy
4Oncology/Hematology, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy
5Istituto di Biomedicina ed Immunologia Molecolare,, Consiglio Nazionale delle Ricerche,, Reggio Calabria, Italy
6Division of Haematology, Arcispedale S. Maria Nuova/IRCCS, Reggio Emilia, Italy, Reggio Emilia, Italy
7Department of Cellular Biotechnologies and Hematology, Sapienza University, Rome, Italy
8Hematology, Ospedale Vito Fazzi, Lecce, Italy
9Department of Clinical and Molecular Biomedicine, University of Catania, Catania, Italy
10Hematology Unit, AO di Reggio Calabria, Reggio Calabria, Italy
11Laboratory of Pre-clinical and Translational Research, IRCCS Rionero in Vulture, Rionero in Vulture, Italy
12Direzione Scientifica, IRCCS San Martino-IST, Genova, Italy
13Section of Hematology, A.O.U. Policlinico, Messina, Italy
14IRCCS Ca’ Granda Ospedale Maggiore Policlinico and University of Milan, MILAN, Italy
15Hematology Unit, A.O. of Cosenza, Cosenza, Italy, Cosenza, Italy
16Section of Hematology, A.O. Pugliese-Ciaccio, Catanzaro, Italy
17San Martino IST, IRCCS, Genova, Italy
18Hematology and BMT Center, Spirito Santo Hospital, Pescara, Italy
19Hematology-Oncology Division,, Garibaldi-Nesima Hospital of Catania, Catania, Italy
20Centro di Riferimento Ematologico-Seconda Medicina, Azianda Ospedaliera Universitaria, Trieste, Italy
21Ematologia, Ospedale San Vincenzo, Taormina, Italy
22Oncohematology Unit, University of Milan, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
23Department of Oncology and Hematology, G. da Saliceto Hospital, Piacenza, Italy
24Oncologia Medica, Università di Modena e Reggio Emilia, Modena, Italy
25Ospedale Papardo, Messina, Italy
26Unità di Ricerca Biotecnologica, Aprigliano (CS), Italy
27Division of Hematology, Mayo Clinic, Rochester, MN
28Scientific Direction, IRCCS San Martino-IST, Genova, Italy
29Department Medical Sciences, Hematology 1 CTMO, University of Milan, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
30Section of Hematology, A.O. L'Annunziata of Cosenza, Cosenza, Italy

Kyle A Udd, BA1*, Laura Z. Rassenti, PhD2, Michael E David, BA1*, James Wang, MD1*, Suzie Vardanyan, MS1*, Julia Linesch1*, Mingjie Li, BS1*, Eric Sanchez, BA1*, Haiming Chen, MD, PhD1, Tanya M. Spektor, PhD3*, Thomas J. Kipps, M.D., PhD.2 and James Berenson, MD1,3

1Institute for Myeloma & Bone Cancer Research, West Hollywood, CA
2University of California San Diego, Moores Cancer Center, La Jolla, CA
3Oncotherapeutics Inc., Los Angeles, CA

Emanuela M. Ghia, PhD1, Laura Z. Rassenti, PhD2, Liguang Chen, MD, PhD3*, Bing Cui, PhD3*, Christopher Deboever, BS4*, Kelly A. Frazer5* and Thomas J. Kipps, M.D., PhD.6

1Moores UCSD Cancer Center, CLL Research Consortium, San Diego, CA
2Moores UCSD Cancer Center, CLL Research Consortium, La Jolla, CA
3Moores Cancer Center, University of California, San Diego, La Jolla, CA
4UCSD, San Diego
5Institute of Genomic Medicine, Department of Pediatrics, University of California San Diego, La Jolla, CA
6UCSD, Moores Cancer Ctr., La Jolla, CA

*signifies non-member of ASH