Anna Staffas, PhD^1,2*, Yuan Wei, MD, PhD^1,3*, Laleh Arabanian^1*, Ann Jansson^2*, Sara Ståhlman^2*, Susanne Li^2*, Linda Fogelstrand, MD, PhD^2,4, Jörg Cammenga, MD, PhD⁵, Florian Kuchenbauer, MD, PhD⁶ and Lars Palmqvist, MD, PhD^2,4

¹Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden
²Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden
³Department of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
⁴Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
⁵Molecular Medicine and Gene Therapy, BMC A12, Lund Stem Cell Center, Lund University, Lund, Sweden
⁶Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany

Flávia Adolfo Corrocher, MSc^*, Ada Congrains, PhD^*, Fernanda Soares Niemann, MSc^*, Bruna Palodetto, MSc^*, Fernanda Marconi Roversi, PhD^*, Mariana Ozello Baratti, PhD^*, Paula de Melo Campos, Ph.D.^* and Sara Teresinha Olalla Saad, PhD, MD

Hematology and Hemotherapy Center-University of Campinas/Hemocentro-Unicamp, Instituto Nacional de Ciência e Tecnologia do Sangue, Campinas, Brazil

Richard L Bennett, Ph.D.¹, Michael T. Byrne, DO², Xiaodong Cheng, MD, PhD^1*, Mohini Patel^1*, Zeel Patel^1*, Amalin Asous^1* and W. Stratford May, MD, PhD¹

¹Department of Medicine, University of Florida, Gainesville, FL
²Division of Hematology-Oncology, Vanderbilt University Medical Center, Nashville, TN

Kerstin Wenzl, MSc^1*, Katharina Troppan, MD^1*, Beata Pursche^1*, Marco Bischof^2*, Christine Beham-Schmid, MD^3*, Hildegard T. Greinix, MD¹, Peter Neumeister, MD^4* and Alexander JA Deutsch, PhD^1*

¹Internal Medicine / Hematology, Medical University Graz, Graz, Austria
²Internal Medicine / Hematology, Medical University of Graz, Graz, Austria
³Institute of Pathology / Hematopathology, Medical University Graz, Graz, Austria
⁴Internal Medicine / Hematology, Medical Universitiy of Graz, Graz, Austria

Marshall S Horwitz, MD, PhD and Matthew R Hart, PhD^*

Department of Pathology, University of Washington School of Medicine, Seattle, WA

Anna Staffas, PhD^1,2*, Edith Schneider, MSc^3*, Linda Fogelstrand, MD, PhD^1,4, Linda Röhner^3*, Michael Heuser, MD⁵, Konstanze Döhner, MD³, Hartmut Döhner, MD^3*, Arefeh Rouhi, PhD^3*, Florian Kuchenbauer, MD, PhD³ and Lars Palmqvist, MD, PhD^1,4

¹Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden
²Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden
³Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
⁴Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
⁵Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany

Catherine C. Coombs, MD¹, Ahmet Zehir, PhD^2*, Sean Devlin, PhD^3*, Sumit Middha, PhD^2*, Donavan Cheng, PhD^2*, Ashwin Kishtagari, MD^1*, David M. Hyman⁴, David Solit, MD^5*, Mark Robson, MD^6*, Jose Baselga, MD, PhD^7*, Maria Arcila, MD^8*, Mark Ladanyi, MD^2*, Martin S Tallman, MD^9*, Ross L. Levine, MD^1,4 and Michael Berger, PhD^8*

¹Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
²Pathology, Memorial Sloan Kettering Cancer Center, New York, NY
³Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY
⁴Memorial Sloan Kettering Cancer Center, New York, NY
⁵Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁶Hereditary Cancer & Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁷Breast Medicine Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁸Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY
⁹Leukemia Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY

Sha Hao, Ph.D^1*, Fang Dong, PhD^1*, Wen Zhou, Ph.D^2*, Hui Cheng, Ph.D.^3*, Shihui Ma, MD^1*, Lugui Qiu, MD, PhD¹ and Tao Cheng, MD³

¹State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Tianjin, China
²Cancer Research Institute, Central South University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education;Key Laboratory of Carcinogenesis, National Health and Family Planning Commission, Changsha, China
³Institute of Hematology & Blood Diseases Hospital, State Key Laboratory of Experimental Hematology, Tianjin, China

Paul Sinclair, PhD.^1*, Joanna Cheng^1*, Prahlad Raninga^2*, Rebecca Hanna^1*, Shaun Hollern^1*, Amir Enshaei, PhD^1*, Helen Blair, PhD^1*, Sirintra Nakjang^1*, Sarra Ryan, PhD^1*, Jeyanthy Eswaran, PhD^1*, Lars Buechler^1*, Olaf Heidenreich, PhD^1* and Christine Harrison, PhD FRCPath FMedSci¹

¹Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom
²The Eskitis Institute for Drug Discovery, Griffith University, Nathan, Australia

Franz X Schaub¹, Weimin Li^1*, Mohammad Fallahi^2*, Chunying Yang^1*, Stephanie K Schaub^1*, Soyoung Lee^3*, Alexandar Tzankov^4*, Clemens Schmitt⁵, Antonio L Amelio^6* and John L. Cleveland^1*

¹Department of Tumor Biology, The Moffitt Cancer Center & Research Institute, Tampa, FL
²Informatics Core, Scripps Florida, The Scripps Research Institute, Jupiter, FL
³Department of Hematology, Oncology and Tumor Immunology, Charité, Universitätsmedizin Berlin, Berlin, Germany
⁴Department of Pathology, University Hospital of Basel, Basel, Switzerland
⁵Max-Delbruck Center for Molecular Medicine, Berlin, Germany
⁶School of Dentistry,Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC

Kevin B Yang^1*, Victor Ng, MS^2*, Gina Ney, MD, PhD³, Lu Liu, PhD^1*, Xi Jin, PhD^1* and Qing Li, MD, PhD⁴

¹University of Michigan, Ann Arbor, MI
²New York University School of Medicine, New York City, NY
³Pediatric Hematology/Oncology, University of Michigan, Ann Arbor, MI
⁴Hematology/Oncology, University of Michigan, Ann Arbor, MI

Tuoen Liu, MD, PhD^1*, Matthew Ndonwi, PhD^2* and Matthew J. Walter, MD³

¹Department of Medicine, Division of Oncology, Washington University in St Louis, St Louis, MO
²Oncology/Stem Cell Biology, Washington University School of Medicine, St. Louis, MO
³Department of Medicine, Division of Oncology, Washington University in St. Louis, Saint Louis, MO

Carmen Doebele^1*, Johannes Kovar^1*, Diego Yepes^1,2*, Silvia Münch^1*, Frank Schnütgen^1*, Hanibal Bohnenberger^3*, Anne Köhler^1*, Henning Urlaub^4,5*, Hubert Serve^1,2,6 and Thomas Oellerich, MD^1,2,7*

¹Dept. of Medicine II, Hematology/Oncology, Goethe University Hospital Frankfurt, Frankfurt/Main, Germany
²German Cancer Research Center, Heidelberg, Germany
³Department of Pathology, Georg August University, Goettingen, Germany
⁴Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany
⁵Bioanalytics, Georg August University, Göttingen, Germany
⁶German Cancer Consortium, Frankfurt, Germany
⁷German Cancer Consortium, Heidelberg, Germany

Shan Lin^1*, Roger T. Luo, PhD², Mark Wunderlich, MS^1*, Joseph J. Kaberlein^2*, Ahmad Rayes, MD, MSc³, John Anastasi, MD^2*, Maureen M O'Brien, MD^3*, James C. Mulloy, PhD¹ and Michael J. Thirman, MD²

¹Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
²University of Chicago, Chicago, IL
³Oncology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Ewa Jablonska, PhD^1*, Patryk Gorniak, PhD^1*, Weronika Prusisz, MSc^1*, Przemyslaw Kiliszek, MSc^1*, Maciej Szydlowski, PhD^1*, Tomasz Sewastianik, MSc^1*, Emilia Bialopiotrowicz, PhD^1*, Anna Polak, MSc^1*, Monika Prochorec-Sobieszek, MD, PhD^1*, Anna Szumera-Cieckiewicz, MD, PhD^1*, Krzysztof Warzocha, MD, PhD^2* and Przemyslaw Juszczynski, MD, PhD^1*

¹Dept. of Diagnostic Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
²Dept. of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland

Bin Lu, Ph.D.^1*, Xueqin Sun, Ph.D.^1*, John Crispino, PhD² and Zan Huang¹

¹College of Life Sciences, Wuhan University, Wuhan, China
²Medicine, Hematology/Oncology, Northwestern University, Chicago, IL

Scott Nadeau, M.S.^1*, Wei An, Ph.D.^2*, Gulzar Ahmad, Ph.D.^3*, Bhopal Mohapatra, Ph.D.^3*, Neha Zutshi^3*, Matthew Storck, M.S.^3*, Seishi Ogawa, MD, PhD⁴, Vimla Band, Ph.D.^3* and Hamid Band, MD, PhD²

¹University of Nebraska Medical Center, OMAHA, NE
²Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE
³University of Nebraska Medical Center, Omaha
⁴Univeristy of Tokyo, Tokyo

Angela Maria Verdoni, PhD^1*, Celia Venezia^1*, Jeffery Klco, MD PhD^2* and Timothy J. Ley, MD³

¹Department of Internal Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University School of Medicine, St. Louis, MO
²St. Jude Children's Research Hospital, Memphis, TN
³Division of Oncology, Department of Internal Medicine, Washington University in St. Louis School of Medicine, St. Louis, MO

Elisa Alghisi, PhD^1*, Martina Konantz, PhD^1*, Marina Mione, MD, PhD^2* and Claudia Lengerke, MD^1,3

¹Department of Biomedicine, University Hospital Basel, Basel, Switzerland
²Institute of Toxicology and Genetics, Karlsruhe Institute of Technology (KIT), Eggenstein- Leopoldshafen, Germany
³Division of Hematology, University Hospital Basel, Basel, Switzerland

Kerstin Maria Kampa-Schittenhelm, MD^1*, Ulrike Mau-Holzmann^2*, Lothar Kanz, Prof. Dr. med.³, Charles Lopez, MD, PhD⁴ and Marcus M Schittenhelm, MD⁵

¹Department of Oncology, Hematology, Rheumatology, Immunology and Pulmology, University of Tuebingen, Tuebingen, Germany
²University of Tuebingen, Tuebingen, Germany
³Department of Oncology, Hematology, Immunology, Rheumatology and Pulmonology, University Hospital Tuebingen, Tuebingen, Germany
⁴Hematology and Medical Oncology, Oregon Health & Science University, Portland, OR
⁵Dept. of Oncology, Hematology, Rheumatology, Immunology and Pulmology, University of Tuebingen, Tuebingen, Germany