Jonathan C. Poe, PhD^1*, Wei Jia, MD^1*, Zhiguo Li, PhD^1*, Frances T. Hakim, PhD^2*, Steven Z. Pavletic, MD², Jeremy J. Rose, BA^2*, David A. Rizzieri, MD¹, Yiping Yang, MD, PhD¹, Benny J. Chen, MD¹, Michael Green, MD^1*, Sarah Anand, MD¹, Christian W. Siebel, PhD^3*, Ivan Maillard, MD, PhD⁴, Nelson J. Chao, MD¹ and Stefanie Sarantopoulos, MD, PhD¹

¹Dept. of Medicine, Div. of Hematological Malignancies & Cellular Therapy, Duke University Medical Center, Durham, NC
²Experimental Transplantation and Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD
³Dept. of Molecular Biology, Genentech, Inc., South San Francisco, CA
⁴Life Sciences Institute, Center for Stem Cell Biology, University of Michigan, Ann Arbor, MI

Natalie Stickel, MSc^1,2,3*, Kathrin Hanke, MSc^1*, Martin Köhler, MSc^2,3,4*, Gabriele Prinz^1*, Dietmar Pfeifer^5*, Annette Schmitt-Graeff, MD^6*, Tilman Brummer, PhD^7*, Juergen Finke, MD¹, Justus Duyster, MD, PhD^1*, Ulrich Salzer, MD^8,9* and Robert Zeiser, MD⁵

¹Department of Hematology, Oncology and Stem Cell Transplantation, Freiburg University Medical Center, Albert Ludwigs University (ALU) Freiburg, Freiburg, Germany
²Spemann Graduate School of Biology and Medicine, ALU Freiburg, Freiburg, Germany
³Faculty of Biology, ALU Freiburg, Freiburg, Germany
⁴Signal Transduction in Tumour Development and Drug Resistance Group, Institute of Molecular Medicine and Cell Research (IMMZ), ALU Freiburg, Freiburg, Germany
⁵Department of Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Freiburg, Germany
⁶Department of Pathology, University Medical Center Freiburg, ALU Freiburg, Freiburg, Germany
⁷BIOSS Centre for Biological Signalling Studies, University of Freiburg, Freiburg, Germany
⁸Department of Rheumatology and Clinical Immunology, Freiburg University Medical Center, ALU Freiburg, Freiburg, Germany
⁹Center for Chronic Immunodeficiency, Freiburg University Medical Center, ALU Freiburg, Freiburg, Germany

Asim Saha, PhD^1*, Roddy S. O'Connor, PhD^2*, Govindarajan Thangavelu, PhD^1*, Scott B. Lovitch, MD, PhD³, Durga Bhavani Dandamudi^4*, Caleph B. Wilson, PhD^5*, Benjamin G. Vincent, MD⁶, Kazutoshi Aoyama^7*, Patricia A. Taylor, DVM⁸, Angela Panoskaltsis-Mortari, PhD⁹, Rocio Foncea, PhD^10*, Joel S. Burrill^10*, Lili Guo^11*, Catarina Sacristan, PhD^4*, Scott N. Furlan, MD^12*, Nathaniel W. Snyder, PhD MPH^11,13*, Ian A. Blair, PhD^11*, Michael C. Milone, MD, PhD^14*, Michael L. Dustin, PhD^15*, James L. Riley, PhD^16*, David A. Bernlohr, PhD^10*, Laurence A. Turka, MD^17*, William J. Murphy, PhD¹⁸, Brian T. Fife, PhD^19*, David H. Munn, MD^20*, Jeffrey S. Miller, MD²¹, Jonathan S. Serody, MD²², Leslie Kean, MD, PhD²³, Gordon J. Freeman, PhD^24*, Arlene H. Sharpe, MD, PhD^25* and Bruce R. Blazar, MD⁸

¹Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN
²Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia
³Brigham and Women's Hosputal, Boston, MA
⁴Department of Pathology, New York University School of Medicine, New York, NY
⁵Department of Microbiology, University of Pennsylvania, Philadelphia, PA
⁶UNC Chapel Hill, Chapel Hill, NC
⁷Department of Hematology, Chugoku Central Hospital, Hiroshima, Japan
⁸Division of Pediatrics, Department of Medicine, University of Minnesota Cancer Center, Minneapolis, MN
⁹Department of Pediatrics, University of Minnesota, Minneapolis, MN
¹⁰Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN
¹¹Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA
¹²Seattle Children's Research Institute, Seattle, WA
¹³Drexel University, Philadelphia, PA
¹⁴Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA
¹⁵Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom
¹⁶Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
¹⁷University of Pennsylvania, Philadelphia, PA
¹⁸Department of Dermatology, UC Davis Medical Center, Sacramento, CA
¹⁹Department of Medicine and Center for Immunology, University of Minnesota, Minneapolis, MN
²⁰Medical College of Georgia, Augusta, GA
²¹Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN
²²Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC
²³Pediatric BMT, Fred Hutchinson Cancer Research Center, Seattle
²⁴Dana-Farber Cancer Institute, Boston, MA
²⁵Pathology, Harvard Medical School, Boston, MA

Tomomi Toubai, MD, PhD¹, Corinne Rossi, MD^1*, Hiroya Tamaki, MD, PhD^2*, Nathan Mathewson, PhD¹, Katherine Oravecz-Wilson, MS^1*, Cynthia Zajac, BS^1*, Chen Liu, MD, PhD^3*, Stuart Brabbs^1*, Yaping Sun, MD, PhD¹, Grace Chen, MD, PhD^4* and Pavan Reddy, MD¹

¹Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI
²Department of Internal Medicine, Division of Hematology and Oncology, Hyogo College of Medicine, Nishinomiya, Japan
³Department of Pathology, University of Florida, Gainesville, FL
⁴Department of Internal Medicine, Division of Gastroenterology, University of Michigan Medical School, Ann Arbor, MI

Katherine Oravecz-Wilson, MS^1*, Corinne Rossi, MD^1*, Chen Liu, MD, PhD^2*, Tomomi Toubai, MD, PhD¹, Hiroya Tamaki, MD, PhD^3*, Cynthia Zajac, BS^1*, Stuart Brabbs^1*, Nathan Mathewson, PhD¹, Julia Wu, BS^4*, Yaping Sun, MD, PhD¹ and Pavan Reddy, MD¹

¹Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI
²Department of Pathology, University of Florida, Gainesville, FL
³Department of Internal Medicine, Division of Hematology and Oncology, Hyogo College of Medicine, Nishinomiya, Japan
⁴Graduate Program in Immunology, University of Michigan Medical School, Ann Arbor, MI

Ludovic Belle, PhD^1*, Kimberle A. Agle, PhD^1*, Vivian Zhou, PhD^1*, Vanessa Yuan, MS^1*, Jie Sun, PhD^2*, Nico Ghilardi, PhD^3*, Jacques van Snick, PhD^4* and William R. Drobyski, MD¹

¹Medical College of Wisconsin, Milwaukee, WI
²Indiana University School of Medicine, Indianapolis, IN
³Genentech, Inc, South San Francisco, CA
⁴Ludwig Cancer Institute, Brussels, Belgium