Type: Poster
Matthew S. Davids, MD, MMSc1, Sikander Ailawadhi2, Asher A. Chanan-Khan, MD3, Boyd Mudenda, MD4*, Larysa Nogaieva, MD5*, Iryna Kryachok, MD6*, Ganna Usenko, MD7*, Vladimir Ivanov, MD8*, Olena Kyselova, MD, PhD9*, Tetiana Perekhrestenko, MD, PhD10*, Ivan Muzhychuk, MD11*, Alexander Myasnikov, MD12*, Les Lukavetsky, MD13*, Andrei Proydakov, MD14*, Olga Uspenskaya, MD15*, Elena Borisenkova, MD16*, Paula Marlton, MBBS17, Tanya Siddiqi, MD, MBBS18*, Allison M. Winter, MD19, Tamila Lysa, MD20*, Bulat Akhatovich Bakirov21*, Tommy Fu, PhD4*, Mingyu Li, PhD4*, Mohammad Ahmad, MD4*, Zi Chen, MD, PhD22*, Zhiyan Liang, PhD4*, Divya J. Mekala, PhD4*, Olena Karpenko, MD9*, Iurii Osipov, MD23*, Asit De, PhD4*, Hengbang Wang, PhD22*, Nashat Gabrail, MD24*, Vinod Ganju, MD25*, Tatiana Konstantinova, MD, PhD26*, Olga Samoilova, MD, PhD27*, Dajun Yang, MD, PhD4,22* and Yifan Zhai, MD, PhD4,22
1Department of Medical Oncology, Dana-Farber Cancer Institute, Inc., Boston, MA
2Mayo Clinic, Jacksonville, FL
3Division of Hematology-Oncology, Mayo Clinic-Florida, Jacksonville, FL
4Ascentage Pharma Group Inc., Rockville, MD
5Communal Nonprofit Enterprise, Clinical Center of Oncology, Hematology, Transplantology and Palliative Care of Сherkasy Oblast Council, Hematology and Bone Marrow Transplantation Division with Chemotherapy Rooms, Cherkasy, Ukraine
6Oncohematology, National Cancer Institute, Ukraine Hemoblastoses of Division of Conservative Methods of Treatment, Kyiv, Ukraine
7Dnipropetrovsk Regional Hematology Center, Dnipro, Ukraine
8Almazov National Medical Research Centre, Saint-Petersburg, Russian Federation
9Medical Center “Ok!Clinic+”, Kyiv, Ukraine
10Medical Center Named by Academician Yuriy Spizhenko (ARENSIA Exploratory Medicine Unit), Kyiv, Ukraine
11SI SP Grygoriev Institute of Radiology of the NAoMS of Ukraine, Kharkiv, Ukraine
12Republican Hospital n.a. V.A. Baranov, St. Petersburg, Russian Federation
13SI “Institute of Blood Pathology and Transfusion Medicine of NAoMS of Ukraine,” Hematology Department, Lviv, Ukraine
14State Institution Komi, Krasnozatonsky, Russian Federation
15Leningrad Regional Clinical Hospital, St. Petersburg, Russian Federation
16Kaluga Regional Clinical Hospital, Kaluga, Russian Federation
17Princess Alexandria Hospital and University of Queensland, Brisbane, Australia
18City of Hope National Medical Center, Duarte, CA
19Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
20Regional Clinical Hospital n. a. O. F. Herbachevskyi, Zhytomyr, Ukraine
21Bashkir State Medical University, Ufa, Russian Federation
22Ascentage Pharma (Suzhou) Co., Ltd., Suzhou, China
23Almazov National Medical Research Center, St. Petersburg, Russian Federation
24Gabrail Cancer Center, Canton, OH
25PASO Medical, Frankston, Australia
26Regional Clinical Hospital No 1, Ekaterinburg, Russian Federation
27Nizhny Novgorod Regional Clinical Hospital named after N A Semashko, Nizhniy Novgorod, Russian Federation
Jan A. Burger, MD, PhD 1, Neil E. Kay, MD2, John N. Allan, MD3, Paul M Barr, MD4, Jacqueline C. Barrientos, MD, MS5*, Carolyn Owen, MD6, Victoria Wang7*, Hsin-Hui Huang, PhD8*, Lynne Neumayr, MD8*, Christopher Abbazio, PharmD8*, Gabriel S. Krigsfeld, PhD8*, Sneh Mody, MBA, PharmD8*, Paolo Ghia, MD, PhD9,10 and Tait D. Shanafelt, MD11*
1MD Anderson Cancer Center, Houston, TX
2Department of Immunology, Mayo Clinic, Rochester, MN
3Division of Hematology and Oncology, Weill Cornell Medicine, Long Island City, NY
4University of Rochester, Rochester, NY
5Mount Sinai Comprehensive Cancer Center, Miami Beach, FL
6Tom Baker Cancer Centre, University of Calgary, Calgary, AB, Canada
7Dana-Farber Cancer Institute, Boston
8AbbVie, North Chicago, IL
9Università Vita-Salute San Raffaele, Milano, Italy
10IRCCS Ospedale San Raffaele, Milan, Italy
11School of Medicine, Stanford University, Stanford, CA
Yuan Yao, MD, MS1, Kari G. Rabe, MS2*, Cristine Allmer, BS2*, Geffen Kleinstern, PhD3*, Nicholas J. Boddicker, PhD2, Shulan Tian, PhD4*, Laura A. Bruins5*, Daniel R. O'Brien4*, Aaron D. Norman, MPH6*, Huihuang Yan, PhD4*, Timothy G. Call, MD1, Paul J. Hampel, MD1, Yucai Wang, MD, PhD1, Eli Muchtar, MD1, Saad S. Kenderian, MD1, Neil E. Kay, MD1,7, Celine M. Vachon, PhD6, James R. Cerhan, MD, PhD2, Susan L. Slager, PhD1, Esteban Braggio, PhD8 and Sameer A. Parikh, MBBS1
1Division of Hematology, Mayo Clinic, Rochester, MN
2Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN
3School of Public Health, University of Haifa, Haifa, ISR
4Division of Computational Biology, Mayo Clinic, Rochester, MN
5Division of Hematology/Oncology, Mayo Clinic, Scottsdale, AZ
6Division of Epidemiology, Mayo Clinic, Rochester, MN
7Department of Immunology, Mayo Clinic, Rochester, MN
8Division of Hematology and Oncology, Mayo Clinic, Scottsdale, AZ
James T. Yoon, MD1*, Yinglu Zhou, MS1*, Svitlana Tyekucheva, PhD1*, Mariia Mikhaleva, MD1*, Stacey M. Fernandes, BS1*, Philippe Armand, MD, PhD1, Amy C. Bessnow, MD, MPH1*, Jennifer L. Crombie, MD1, David C. Fisher, MD1, Eric D. Jacobsen, MD1, Caron A. Jacobson, MD, MMSc1, Austin I. Kim, MD1, Ann S. LaCasce, MD, MMSc1, Reid W. Merryman, MD1, Oreofe O. Odejide, MD1, Erin M. Parry, MD, PhD1, David A. Qualls, MD1, Christine E. Ryan, MD1, Aswin Sekar, MD, PhD1, Jacob D. Soumerai, MD2, Jon E. Arnason, MD3, Matthew S. Davids, MD, MMSc1, Jennifer R. Brown, MD, PhD1 and Inhye E. Ahn, MD1
1Dana-Farber Cancer Institute, Boston, MA
2Center for Lymphoma, Massachusetts General Hospital Cancer Center, Boston, MA
3Beth Israel Deaconess Medical Center, Boston, MA
Florian Simon, MD1*, Rudy Ligtvoet, PhD1*, Jan-Paul Bohn2*, Thomas Noesslinger3*, Julia Von Tresckow, MD4*, Ruediger Liersch5*, Tobias Gaska, MD6, Kathleen Jentsch-Ullrich, MD7*, Michael Gärtner, MD8*, Thomas Wolff9*, Ingo Schwaner10*, Dominik Wolf, M.D.11*, Christof Schneider, MD12*, Ursula Vehling-Kaiser, MD13*, Matthias Ritgen14*, Christian Spoer15*, Michael J. Eckart, MD16*, Thomas Decker17*, Geothy Chakupurakal, MBBS18, Björn Schöttker19*, Jens Kisro, MD, PhD20, Janina Stumpf1*, Eugen Tausch, MD12*, Stephan Stilgenbauer, MD12, Karl-Anton Kreuzer21*, Sandra Robrecht, PhD22,23*, Anna Maria Fink, MD22*, Moritz Fürstenau, MD24*, Kirsten Fischer, MD22*, Valentin Goede, MD25*, Michael Hallek, MD26* and Barbara F. Eichhorst, MD27
1Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf; German CLL Study Group, University of Cologne, Cologne, Germany
2Department of Internal Medicine V, Division of Hematology & Oncology, Medical University of Innsbruck, Innsbruck, AUT
3Medizinische Abteilung für Hämatologie und Onkologie; Hanusch Krankenhaus, Vienna, Austria
4Clinic for Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
5Gemeinschaftspraxis für Hämatologie und Onkologie, Clemenshospital Münster, Münster, Germany
6Brüderkrankenhaus St. Josef, Paderborn, DEU
7Gemeinschaftspraxis für Hämatologie und Onkologie, Magdeburg, DEU
8Onkologisches Ambulanzzentrum Hannover (OAZ), Hannover, Germany
9Oncoresearch Lerchenfeld UG, Hamburg, Germany
10Onkologische Schwerpunktpraxis Kurfürstendamm, Berlin, Germany
11Department of Medicine V, Medical University of Innsbruck, Innsbruck, Austria
12Department of Internal Medicine III, Division of CLL, University Hospital Ulm, Ulm, Germany
13Outpatient Clinic, Landshut, Germany
14Department of Internal Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany
15MVZ Klinikum Deggendorf GmbH, Deggendorf, Germany
16Onkologische Schwerpunktpraxis Erlangen, Erlangen, Germany
17Onkologie Ravensburg, Ravensburg, DEU
18Praxis für Hämatologie und Onkologie Koblenz, Koblenz, DEU
19Hämatologisch-onkologische Schwerpunktpraxis Würzburg, Würzburg, Germany
20Lübecker Onkologische Schwerpunktpraxis, Lübeck, DEU
21Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf; German CLL Study Group, University of Cologne, Cologne, Cologne, DEU
22Department I of Internal Medicine, Faculty of Medicine and Cologne University Hospital, Cologne, Germany
23German CLL Study Group, University of Cologne, Cologne, Germany
24Department I of Internal Medicine, Faculty of Medicine and Cologne University Hospital, Koeln, Germany
25St. Marienhospital Cologne, Oncogeriatric Unit, Department of Geriatric Medicine, Cologne, Germany
26CECAD, Center of Excellence on Cellular Stress Responses in Aging-Associated Diseases, Center for Molecular Medicine, Cologne, Germany
27Department I of Internal Medicine and Center of Integrated Oncology Aachen Bonn Cologne Düsseldorf, German CLL Study Group, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany
T C1*, Eva Minga2*, Georgios Karakatsoulis2*, Elisa Albi3*, Miguel Alcoceba4*, David Allsup5*, Francesca Bacchiarri, MD6*, Sotiria Besikli-Dimou2*, Sofia Chatzileontiadou7*, Rosa Collado8*, Zadie Davis9*, Maria Dimou, MD10*, David Donaldson11*, Maria Efstathopoulou12*, Sara Galimberti, MD13*, Andrea Galitzia, MD14*, Eva Gimeno15*, Valerio Guarente, MD16*, Eleftheria Hatzimichael, MD, PhD17*, Jose-Angel Hernandez-Rivas18*, Gloria Iacoboni, MD19*, Iliana Konstantinou20*, Ioannis Kotsianidis21*, Jana Kotaskova22*, Andreas Epameinondas Koumpis23*, Zuzana Kubova, MD24*, Jorge Labrador, MD25*, Luca Laurenti, MD26,27*, Juan Marquet, MD28*, Stanislava Maslejova, MD22*, Carlota Mayor-Bastida29*, Fatima Miras30*, Riccardo Moia, MD31*, Almudena Navarro-Bailon32*, Jacopo Olivieri, MD, PhD33*, Maria Papaioannou7*, Anna Puiggros, PhD34*, Gian Matteo Rigolin35*, Mattia Schipani36*, Tereza Shokralla37*, Martin Simkovic38*, Antigoni Tranidou1*, Theodoros Vassilakopoulos10*, Andrea Visentin39*, Candida Vitale, MD, PhD40*, George Vrachiolias41*, Renata Walewska, MD, PhD42*, Lucrecia Yanez San Segundo43,44*, Jana Zuchnicka45*, David Graham Oscier42, Alessandro Gozzetti46*, Panayiotis Panayiotidis, MD10, Francesc Bosch, MD, PhD47, Paolo Sportoletti, BSc16*, Blanca Espinet, PhD34*, Gerassimos Pangalis, MD48*, Maria Angelopoulou10*, Tomas Papajik, MD, PhD49*, Roberta Murru50*, Marta Coscia, MD, PhD40*, Antonio Cuneo, MD51*, Gianluca Gaidano, MD, PhD36, Niki Stavrogianni, MD52*, Livio Trentin53, Lukas Smolej38*, Mark Caterwood11*, Martin Spacek54*, Sarka Pospisilova, Prof55*, Michael Doubek, Prof55, Anastasia Chatzidimitriou2*, Kostas Stamatopoulos2*, Paolo Ghia, MD, PhD56,57 and Lydia Scarfo, MD3,58
1Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece, Thessaloniki, Greece
2Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece
3Strategic Research Program on CLL, IRCCS Ospedale San Raffaele, Milano, Italy
4Hospital Universitario de Salamanca. (HUS/IBSAL), CIBERONC, and Centro de Investigación del Cáncer (CIC/USAL, Salamanca, Spain
5Hull York Medical School, Hull, United Kingdom
6Division of Hematology, University of Siena, Siena, ITA
71st Department of Internal Medicine, AHEPA University Hospital of Thessaloniki, Thessaloniki, Greece
8Hospital Clínico Universitario de Valencia, Instituto de Investigación Sanitaria INCLIVA, Valencia, ESP
9Molecular Pathology, University Hospitals Dorset, Royal Bournemouth Hospital, Bournemouth, United Kingdom
10Department of Hematology and Bone Marrow transplantation Unit, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece
11Haematology Department, Belfast City Hospital, Belfast, United Kingdom
12Department of Haematology Athens Medical Center-Psychikon Branch, Athens, Greece
13Department of Clinical and Experimental Medicine, Hematology, University of Pisa, Pisa, Italy
14Hematology and Stem Cell Transplantation Unit, Ospedale San Francesco, Hematology and Stem Cell Transplantation Unit, Ospedale San Francesco, Nuoro, Italy
15Department of Hematology, Hospital del Mar, Barcelona, Spain
16Institute of Hematology and Center for Hemato-Oncology Research, University of Perugia and Santa Maria della Misericordia Hospital, Perugia, Italy
17Department of Hematology, Faculty of Medicine, University of Ioannina, Ioannina, Greece
18Hematology Department Infanta Leonor University Hospital, Madrid, Spain
19Hospital Universitari Vall d’Hebron-Universitat Autónoma de Barcelona, SEATTLE, WA
20Department of Haematology, University of Athens, Laikon General Hospital, Athens, Athens, Greece
21Department of Hematology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis, Greece
22Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic
23Department of Haematology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece
24Department of Hemato-Oncology, Faculty of Medicine and Dentistry, Palacký University and University Hospital Olomouc, Olomouc, Czech Republic
25Department of Hematology, Hospital Universitario de Burgos, Universidad Isabel I, Burgos, Spain
26Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Agostino Gemelli University Hospital Foundation IRCCS, Rome, Italy
27Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche, Roma, Università Cattolica del Sacro Cuore, Rome, Italy
28Hematology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain
29Haematology Department, Hospital Universitario de La Princesa, Madrid, Spain
30Hematology Department Hospital Universitario 12 de Octubre, Madrid, Spain
31Division of Hematology, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy
32Hematology Department, IBSAL-University Hospital of Salamanca. University of Salamanca., Salamanca, Spain
33Hematology Clinic, ASUFC, Udine, Italy
34Molecular Cytogenetics Laboratory, Pathology Department, Hospital del Mar and Translational Research on Hematological Neoplasms Group, Hospital del Mar Research Institute (IMIM), Barcelona, Spain
35Hematology Section, St. Anna University Hospital, Ferrara, Italy
36Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy
371st Department of Medicine - Hematology, First Faculty of Medicine, Charles University and General Hospital in Prague, Prague, Czech Republic
384th Department of Internal Medicine – Haematology, Faculty of Medicine in Hradec Kralove, University Hospital and Charles University in Prague, Hradec Kralove, Czech Republic
39Hematology Unit, Department of Medicine, University of Padova, Padova, ITA
40Division of Hematology, A.O.U. Città della Salute e della Scienza di Torino and Department of Molecular Biotechnology and Health Sciences, University of Torino, Turin, Italy
41Democritus University of Thrace, Department of Hematology, University Hospital of Alexandroupolis, Alexandroupolis, Greece, Alexandroupolis, Greece
42Department of Haematology, Royal Bournemouth Hospital, Bournemouth, United Kingdom
43University Hospital MarquéS De Valdecilla - IDIVAL, Santander, Spain
44Department of Hematology, University Hospital Marqués de Valdecilla, Santander, Spain
45Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
46Division of Hematology, University of Siena, Siena, Italy
47Hematology Department, Vall d’Hebron Institute of Oncology (VHIO), University Hospital Vall d’Hebron, Barcelona, Spain
48Department of Haematology, Psychicon Branch, Athens Medical Center, Athens, Greece
49Department of Hemato-Oncology, Faculty of Medicine and Dentistry, Palacky University and University Hospital, Olomouc, Czech Republic
50Hematology and Stem Cell Transplantation Unit, Ospedale Oncologico A. Businco, ARNAS "G. Brotzu", Cagliari, Italy
51Division of Hematology, University of Ferrara, Ferrara, Ferrara, Italy
52Hematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece
53Hematology Unit, Department of Medicine, University of Padova, Padova, Italy
541st Department of Medicine - Haematology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic
55Department of Internal Medicine – Hematology and Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic
56IRCCS Ospedale San Raffaele, Milan, Italy
57Università Vita-Salute San Raffaele, Milano, Italy
58Medical School, Università Vita-Salute San Raffaele, Milano, Italy
Christopher Pleyer, MD1, Emily Tomasulo, DO2*, Jeanine Superata, MS, CRNP1*, Rachel Adams3*, Xin Tian, PhD4*, Jayson Grey3*, Pia Nierman, RN1*, Adrian Wiestner, MD5 and Clare Sun, MD6
1National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
2Division of Hematology/Oncology, Department of Medicine, Pennsylvania Hospital, Philadelphia, PA
3National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD
4Office of Biostatistics Research, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD
5Laboratory of Lymphoid Malignancies, Hematology Branch, NIH, NHLBI, Bethesda, MD
6National Heart, Lung, and Blood Institute, National Heart, Lung and Blood Institute, Bethesda, MD
Alberto Fresa, MD1,2*, Idanna Innocenti, MD, PhD3*, Annamaria Tomasso, MD4*, Candida Vitale, MD, PhD5*, Alessandro Sanna, MD6*, Anna Maria Frustaci, MD7*, Andrea Visentin, MD, PhD8*, Azzurra Anna Romeo, MD9*, Paolo Sportoletti10*, Annamaria Giordano, MD11*, Francesca Perutelli, MD5*, Roberta Murru, MD12*, Francesca Romana Mauro, MD13*, Antonio Mosca, MD14*, Francesca Morelli, MD15*, Roberta Laureana, MD16*, Andrea Galitzia, MD17*, Ilaria Angeletti, MD18*, Esmeralda Conte, MD19*, Riccardo Moia, MD20*, Giovanni Francesco D'Arena, MD21*, Raffaella Pasquale, MD22*, Francesco Autore, MD, PhD23*, Jacopo Olivieri, MD22*, Luca Stirparo, MD14*, Giulia Benintende, MD24*, Andrea Corbingi, MD9*, Maria Ilaria Del Principe16*, Diana Giannarelli, PhD25*, Alessandra Tedeschi, MD7*, Marta Coscia, MD, PhD26,27*, Eugenio Sangiorgi, MD, PhD28*, Dimitar G Efremov, MD, PhD29 and Luca Laurenti, MD14,30*
1Hematology-Oncology and Stem-Cell Transplantation Unit, Department of Onco-Hematology and Innovative Diagnostics, Istituto Nazionale Tumori IRCCS - Fondazione "G. Pascale", Naples, Italy
22. Hematology Section, Deparment of Radiological and Hematological Sciences, Catholic University of Sacred Heart, Rome, Italy
3Department of Laboratory and Haematological Sciences, Haematology Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Catholic University of Sacred Heart, Roma, Italy
4Catholic University of Sacred Heart, Hematology Section, Department of Radiological and Hematological Sciences, Rome, Italy
5Department of Molecular Biotechnology and Health Sciences, University of Torino and Division of Hematology, University Hospital (A.O.U.) Città della Salute e della Scienza di Torino, Torino, Italy
6Hematology, Department of Oncology, AOU Careggi, Firenze, Italy
7Department of Hematology, Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy
8Hematology unit, Department of Medicine, University of Padova, Padova, Italy
9Hematology and Stem Cell transplantation Unit, S.M. Goretti Hospital, Polo Universitario Pontino, "Sapienza”, Latina, Italy
10Department of Medicine and Surgery, Institute of Hematology, Centro di Ricerca Emato Oncologica (CREO), University of Perugia, Perugia, Italy
11Unit of Hematology and Stem Cell Transplantation, AOUC Policlinico, and Department of Precision and Regenerative Medicine and Ionian Area, "Aldo Moro" University School of Medicine, Bari, Italy, Bari, Italy
12Hematology and Stem Cell Transplantation Unit, Ospedale Oncologico A. Businco, ARNAS "G. Brotzu", Cagliari, Italy
13Hematology, Department of Translational and Precision Medicine, Sapienza University, Roma, Italy
14Hematology Section, Department of Radiological and Hematological Sciences, Catholic University of Sacred Heart, Rome, Italy
15Department of Hematology, University of Florence, Firenze, Italy
16Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
17Hematology and Stem Cell Transplantation Unit, Ospedale San Francesco, Hematology and Stem Cell Transplantation Unit, Ospedale San Francesco, Nuoro, Italy
18Department of Onco-hematology, Azienda Ospedaliera Santa Maria di Terni, Terni, Italy
19Hematology Unit, Department of Clinical and Molecular Medicine, Sant'Andrea University Hospital, Sapienza University, ROMA, ITA
20Division of Hematology, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy
21Hematology and Stem Cell Transplantation Unit, IRCCS Centro Di Riferimento Oncologico Della Basilicata, Rionero In Vulture, PZ, ITA
22SOC Clinica Ematologia, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Udine, Italy
23Hematology Section, Department of Radiological and Hematological Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy
24Department of Medicine 5, Haematolgy and Oncology, Friedrich-Alexander-Universitat Erlangen-Nurnberg (FAU), Universitatsklinkum, Erlangen, Germany
25Facility of Epidemiology and Biostatistics, GSTeP, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy
26Department of Medicine and Surgery, University of Insubria, Varese, Italy
27Hematology Division, ASST Sette Laghi, Ospedale di Circolo, Varese, Italy
28Genomic Medicine Section, Department of Life Sciences and Public Health, Catholic University of Sacred Heart, Rome, Italy
29Molecular Hematology, International Centre for Genetic Engineering and Biotechnology, Trieste, TS, Italy
30Hematology Section, Department of Radiological and Hematological Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy;, Rome, Italy
Jennifer A. Woyach, MD1, Danielle M. Brander, MD2, Boyu Hu, MD3, Kerry A. Rogers, MD4, Zulfa Omer, MD5, Deborah M. Stephens, DO6, Andrea Sitlinger, MD7*, Fenlai Tan8*, Yi Chen, PhD9*, Stephen P. Anthony, DO10, Yu Chen, MD, PhD9, Kewei Shang, MD11* and John C. Byrd, MD12
1The Ohio State University, Columbus, OH
2Duke University, Durham, NC
3Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
4Division of Hematology, The Ohio State University, Columbus, OH
5Division of Hematology, University of Cincinnati, Cincinnati, OH
6University of North Carolina Chapel Hill, Chapel Hill, NC
7Duke Cancer Center, Durham, NC
8Guangzhou Lupeng Pharmaceutical Co., Ltd., Guangzhou, China
9Newave Pharmaceutical Inc., Pleasanton, CA
10Newave Pharmaceutical Inc., Colbert, WA
11Newave Pharmaceuticals, Pleasanton, CA
12Department of Internal Medicine, University of Cincinnati, Cincinnati, OH
Alan P Skarbnik, MD1, Alexey V. Danilov, MD, PhD2, Marc Hoffmann, MD3, Farrukh T. Awan, MD4, Frank Scarpa5*, Caryn Davies5*, Todd Oakland6*, Marina Kovach6*, Jenna Lilyquist6*, Veerendra Munugalavadla, PhD7, Alan SM Yong, MD7*, Vikram Shetty, MD7*, John N. Allan, MD8 and Jennifer A. Woyach, MD9
1Novant Health Cancer Institute, Charlotte, NC
2City of Hope National Medical Center, Duarte, CA
3University of Kansas Medical Center, Kansas City, KS
4University of Texas Southwestern Medical Center, Dallas, TX
5NeoGenomics Laboratories, Fort Myers, FL
6ConcertAI LLC, Cambridge, MA
7AstraZeneca, Gaithersburg, MD
8Weill Cornell Medical Center, New York, NY
9The Ohio State University, Columbus, OH
Yuting Yan, MD1*, Yulan Zhou2*, Weihao Chen3*, Jun Wang4*, Tingyu Wang1*, Ying Yu5*, Yujiao Jia, MD6*, Zhen Yu7*, Lugui Qiu1, Fei Li8 and Shuhua Yi9*
1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
2Center of Hematology, The First Affiliated Hospital of Nanchang University, Nanchang, China
3State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology& Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjjn, China
41. State Key Laboratory of Experimental Hematology, National Clinical Research C, Tianjin, CHN
5State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical Colleg, Tianjin, China
6State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Tianjin, China
7State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology& Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
8Department of Hematology, The First Affiliated Hospital of Nanchang University, Nanchang, China
9State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences&Peking Union Medical College, Tianjin, China
Nicole Lamanna, MD1*, Jennifer R. Brown, MD, PhD2, Chaitra S. Ujjani, MD3, Toby A. Eyre4*, Beenish Manzoor5*, Nilanjan Ghosh6*, Lindsey Roeker, MD7, Matthew S. Davids, MD, MMSc2, Catherine C Coombs, MD8*, Alan P Skarbnik, MD9, Brian T. Hill, MD, PhD10, Hande H. Tuncer, MD2, Lori A. Leslie, MD11*, Joanna M. Rhodes, MD, MSCE12*, Isabelle Fleury, MD, MSc13, Paul M Barr, MD14, Nnadozie Emechebe5*, Nicolas Martinez-Calle15*, Christopher E. Jensen16*, Yun Choi17*, Dureshahwar Jawaid5*, Laurie K Pearson, MD18, Meghan C. Thompson, MD7, Steven E Marx5*, Wendy Sinai, PharmD19*, Frederick Lansigan, MD20*, Bita Fakhri, MD, MPH21, Deborah M. Stephens, DO22, Stephen J. Schuster, MD23, Michael Coyle24*, Irina Pivneva, PhD25*, Talissa Watson25*, Annie Guerin, MSc25* and Mazyar Shadman3*
1Columbia University, New York, NY
2Dana-Farber Cancer Institute, Boston, MA
3Fred Hutchinson Cancer Research Center, Seattle, WA
4Churchill Hospital, Oxford University, Oxford, United Kingdom
5AbbVie Inc., North Chicago, IL
6Levine Cancer Institute, Atrium Health, Charlotte, NC
7CLL Program, Leukemia Service, Division of Hematologic Oncology, Memorial Sloan Kettering Cancer Center, New York, NY
8University of California Irvine, Irvine, CA
9Lymphoma and CLL Program, Novant Health Cancer Institute, Charlotte, NC
10Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
11John Theurer Cancer Center, Hackensack Meridian Health, Hackensack, NJ
12Rutgers Cancer Institute of New Jersey, New Brunswick, NJ
13Hôpital Maisonneuve-Rosemont, University of Montreal, Montreal, Canada
14University of Rochester, Rochester, NY
15Nottingham University Hospitals, NHS Trust, Nottingham, United Kingdom
16University of North Carolina Chapel Hill, Chapel Hill, NC
17Tufts Medical Center, Boston, MA
18University of Massachusetts, Worcester, MA
19Senior Scientific Director, AbbVie, AbbVie, North Chicago, IL
20Dartmouth-Hitchcock Medical Center, Lebanon
21Stanford Cancer Institute, Stanford University, Stanford, CA
22Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC
23University of Pennsylvania, Philadelphia, PA
24Lowell General Hospital, Lowell, MA
25Analysis Group, Inc., Montreal, QC, Canada
Billy Jebaraj, PhD1*, Eugen Tausch, MD1*, Deyan Y. Yosifov, PhD2*, Christof Schneider, MD1*, Moritz Fürstenau, MD3*, Can Zhang, PhD4,5*, Sandra Robrecht, PhD6*, Caspar da Cunha-Bang, MD, PhD7*, Mark-David Levin8, Philipp Bernhard Staber, MD, PhD9, Tamar Tadmor, MD10*, Patrick Thornton11*, Michael Gregor, MD12*, Anna Maria Fink, MD4*, Kirsten Fischer, MD6*, Matthias Ritgen13*, Michael Hallek, MD6*, Arnon P. Kater, MD, PhD14, Carsten Utoft Niemann, MD, PhD7*, Barbara F. Eichhorst, MD6 and Stephan Stilgenbauer, MD1,15
1Department of Internal Medicine III, Division of CLL, University Hospital Ulm, Ulm, Germany
2Department of Internal Medicine III, Division of CLL, Ulm University, Ulm, Baden-Württemberg, Germany
3Department I of Internal Medicine, Faculty of Medicine and Cologne University Hospital, Koeln, Germany
4Faculty of Medicine and Cologne University Hospital, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Cologne, Germany, Cologne, Germany, Cologne, Germany
5German CLL Study Group, Cologne, NRW, DEU
6Department I of Internal Medicine, Faculty of Medicine and Cologne University Hospital, Cologne, Germany
7Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
8Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, Netherlands
9Department of Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria
10Bnai Zion, Haifa, Israel
11Department of Haematology, Beaumont Hospital, RCSI, Cancer Trials Ireland, Dublin, Dublin, IRL
12Division of Hematology, Cantonal Hospital of Lucerne, Lucerne, Switzerland, Lucerne, Switzerland
13Department of Internal Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany
14Dept of Hematology, Cancer Center Amsterdam, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands
15Comprehensive Cancer Center Ulm, University of Ulm, Ulm, Germany
Keshu Zhou1*, Hongyun Xing2*, Qingliang Teng3*, Wuping Li4*, Yafei Wang5*, Feng Zhu6*, Zhengming Jin, M.D.7*, Li Zhiming8*, Guifang Ouyang9*, Fang Xu10*, Shihua Huang11* and Jianyong Li, MD12
1Department of Hematology, the Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China
2Department of Hematology, The Affiliated Hospital of Southwest Medical University, Luzhou, China
3Department of Hematology, Taian City Central Hospital, Taian, China
4Department Of Lymphoma And Hematology, Jiangxi Cancer Hospital, Nanchang, China
5Department Of Hematology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Tianjin, China
6Department Of Hematology, The Affiliated Hospital of XuZhou Medical University, Xuzhou, China
7Department of Hematology, Collaborative Innovation Center of Hematology, Institute of Blood and Marrow Transplantation, the First Affiliated Hospital of Soochow University, Suzhou, China
8Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China
9Department of Hematology, The First Affiliated Hospital of Ningbo University, Ningbo, China
10Department of Hematology, Mianyang Central Hospital, Mianyang, China
11Department Of Hematology, Yibin Second People's Hospital, Yibin, China
12First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
Jennifer L. Crombie, MD1, Christine E. Ryan, MD2, Yue Ren, MS2*, Svitlana Tyekucheva, PhD3*, Celeste Carey1*, Aaron Zou, BA1*, Samantha Normilus, BSN1*, Josie Montegaard, NP1*, Jacob D. Soumerai, MD4, Shruti Bhandari, MD5*, Jon E. Arnason, MD6, Alvaro J Alencar, MD7, Austin I. Kim, MD8, Erin M. Parry, MD, PhD2, Philippe Armand, MD, PhD2, David C. Fisher, MD2, Jennifer R. Brown, MD, PhD9 and Matthew S. Davids, MD, MMSc10
1Dana-Farber Cancer Institute, Boston, MA
2Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
3Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
4Center for Lymphoma, Massachusetts General Hospital Cancer Center, Boston, MA
5Department of Hematology and Oncology, Northern Light Cancer Care, Brewer, ME
6Beth Israel Deaconess Medical Center, Boston, MA
7Sylvester Comprehensive Cancer Center, Division of Hematology, University of Miami, Miller School of Medicine, Miami Beach, FL
8Department of Medical Oncology, Dana-Farber Cancer Institute, Newton Center, MA
9Department of Medical Oncology, Dana-Farber Cancer Institute, Newton, MA
10Department of Medical Oncology, Dana-Farber Cancer Institute, Inc., Boston, MA
Anthony G Mansour, MD1, Ying Huang, MS, MA2, Aseel Alsouqi, MD3*, Adam S Kittai, MD4, John C. Byrd, MD5, Michael R. Grever, MD3, Cecelia Miller, PhD6, Gerard Lozanski, MD6*, Mollie Moran, CNP3*, Margaret S. Lucas, PA-C3*, Swetha Suresh, CNP3*, Cara Grantier, CNP3*, Corinne Hoffman, MS, NP3*, Mark Reid, CNP3*, Kerry A. Rogers, MD3, Seema A Bhat, MD3 and Jennifer A. Woyach, MD3
1Department of Internal Medicine, The Ohio State University, Columbus, OH
2Division of Hematology, Department of Statistics, The Ohio State University Wexner Medical Center, Columbus, OH
3Division of Hematology, The Ohio State University, Columbus, OH
4Icahn School of Medicine at Mount Sinai, New York, NY
5Department of Internal Medicine, University of Cincinnati, Cincinnati, OH
6Division of Pathology, The Ohio State University, Columbus, OH
Stefano Molica, MD1*, David Allsup, MD2* and Diana Giannarelli, PhD3*
1Department Hematology, Hull University Teaching Hospitals NHS Trust, Hull, UK, Department Hematology, Hull University Teaching Hospitals NHS Trust, Hull, UK, Hull, Italy
2Castle Hill Hospital, Cottingham, GBR
3Biostatistics Unit,, b Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy, Rome, Italy
Jan A. Burger, MD, PhD 1, Ekaterina Kim, PhD, MS1*, Gitanjali Jayachandran, PhD2*, Thomas Mathew1*, Koji Sasaki, MD1, Yesid Alvarado Valero, MD1, Danielle Hammond, MD1, Fadi G. Haddad, MD1, William G. Wierda1 and Alessandra Ferrajoli, MD1
1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston
Mazyar Shadman, MD, MPH1,2, Ian W. Flinn, MD, PhD3, Moshe Y. Levy, MD4*, Benjamin B. Freeman, MD5, Ben Zhang, MD6*, John M. Burke7, Jennifer L. Cultrera, MD8, Habte A. Yimer, MD9, Edwin C. Kingsley, MD10*, Charles M. Farber, MD, PhD11*, James D'Olimpio, MD12*, Hui Yao13*, Adam Idoine, PhD14*, Qi An13* and Jeff P. Sharman, MD15
1Fred Hutchinson Cancer Research Center, Seattle, WA
2University of Washington, Seattle, WA
3Tennessee Oncology/OneOncology, Nashville, TN
4Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas, TX
5Summit Medical Group, Florham Park, NJ
6Minnesota Oncology Clinic, Burnsville, MN
7Rocky Mountain Cancer Centers, US Oncology Research, Aurora, CO
8Florida Cancer Specialists & Research Institute, Leesburg, FL
9Texas Oncology-Tyler, US Oncology Research, Tyler, TX
10Comprehensive Cancer Centers of Nevada, Las Vegas, NV
11Morristown Medical Center, Atlantic Hematology Oncology, Morristown, NJ
12Clinical Research Alliance, Westbury, NY
13BeiGene (Shanghai) Co, Ltd, Shanghai, China
14BeiGene USA, Inc, San Mateo, CA
15Willamette Valley Cancer Institute and Research Center, US Oncology Research, Eugene, OR
Tanya Siddiqi, MD, MBBS1*, Jordan Gauthier, MD, MSc2*, Saad S. Kenderian, MD3, Danielle M. Brander, MD4, Kathleen Dorritie, MD5, Jacob D. Soumerai, MD6, Peter A. Riedell, MD7, Nirav N. Shah, MD8, Rajneesh Nath, MD9, Charalambos Andreadis, MD, MS10*, Daniel A. Ermann, MD11, Shuo Ma, MD, PhD12, Tatyana Feldman, MD13*, Scott R. Solomon, MD14, Stephen J. Schuster, MD15, Sherilyn A. Tuazon, MD16*, Serena K. Perna, MD17*, San-San Ou, MS16*, Neha Rane, MD17*, Eniko Papp, PhD16*, Yizhe Chen, PhD17* and William G. Wierda18
1City of Hope National Medical Center, Duarte, CA
2Fred Hutchinson Cancer Center, Seattle, WA
3Mayo Clinic, Rochester, MN
4Duke Cancer Institute, Durham, NC
5UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA
6Center for Lymphoma, Massachusetts General Hospital Cancer Center, Boston, MA
7David and Etta Jonas Center for Cellular Therapy, University of Chicago, Chicago, IL
8Medical College of Wisconsin, Milwaukee, WI
9Banner MD Anderson Cancer Center, Scottsdale, AZ
10University of California, San Francisco, San Francisco, CA
11Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
12Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Northwestern University, Chicago, IL
13John Theurer Cancer Center at Hackensack Meridian Health, HMH School of Medicine, Hackensack, NJ
14Northside Hospital Cancer Institute, Atlanta, GA
15Lymphoma Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
16Bristol Myers Squibb, Seattle, WA
17Bristol Myers Squibb, Princeton, NJ
18The University of Texas MD Anderson Cancer Center, Houston, TX
Lisa Blixt, MD1,2*, Pontus Hedberg, MD, PhD3*, Sandra Eketorp Sylvan, MD, PhD4*, Isabela Killander Möller5*, Hannes Lindahl6,7*, Fredrik Kahn8,9*, Åsa Nilsdotter-Augustinsson10*, Mats Fredrikson11*, Sofia Nyström12,13*, Richard Rosenquist, MD, PhD14,15, Peter Bergman, MD, PhD6,16*, Christina Carlander, MD, PhD5,17*, Soo Aleman, MD, PhD17,18*, Anders Österborg, MD, PhD1,19* and Lotta Hansson, MD, PhD1,19*
1Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden
2Department of Hematology, Karolinska University Hospital, Sollentuna, Sweden
3Department of Medicine Huddinge, Karolinska Institutet, Stockholm, SWE
4Department of Oncology-Pathology, Karolinska Institutet, Stockholm, SWE
5Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden
6Department of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, Sweden
7Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
8Department of Infectious Diseases, Skåne University Hospital, Lund, Sweden
9Department of Clinical Sciences Lund, Section for Infection Medicine, Lund University, Lund, SWE
10Division of Inflammation and Infection, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden
11Department of Biomedical and Clinical Sciences, Faculty of Medicine, Linköping University, Linköping, Sweden
12Department of Clinical Immunology and Transfusion Medicine, Linköping University, Linköping, Sweden
13Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden
14Department of Clinical Genetics and Genomics, Karolinska University Hospital, Stockholm, Sweden
15Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
16Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
17Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden
18Department of Medicine Huddinge, Division of Infectious Diseases and Dermatology, Karolinska Institutet, Stockholm, Sweden
19Department of Hematology, Karolinska University Hospital, Stockholm, Sweden
Adam S Kittai, MD1, Ying Huang, MS, MA2, Seema A Bhat, MD2, Michael R. Grever, MD2, Swetha Suresh, CNP2*, Gerard Lozanski, MD3*, Mollie Moran, CNP2*, Megan Nussbaum2*, Jennifer A. Woyach, MD2 and Kerry A. Rogers, MD2
1Icahn School of Medicine at Mount Sinai, New York, NY
2Division of Hematology, The Ohio State University, Columbus, OH
3Division of Pathology, The Ohio State University, Columbus, OH
Jennifer J. Huang, MD, PhD1,2, Laura Samples, MD1,2, Margie Fredericks, MSN, ARNP2*, Stephanie Louie, RN3*, Ramya Pulluru2*, Christine Crider2*, Mehrdad Shakib-Azar2*, Neena Kennedy2*, Vikram Raghunathan, MD1,2*, Christina Poh, MD1,2, Mengyang Di, MD, PhD2,4, Stephen D. Smith, MD1,2, Brian G. Till, MD1,5, Ajay K. Gopal, MD1,2, Chaitra S. Ujjani, MD1,2, Ryan C. Lynch, MD1,2 and Mazyar Shadman, MD, MPH1,2
1University of Washington, Seattle, WA
2Fred Hutchinson Cancer Center, Seattle, WA
3Fred Hutchinson Cancer Center, Seattle
4Division of Hematology and Oncology, University of Washington, Seattle, WA
5Fred Hutchinson Cancer Center, University of Washington, Seattle, WA