Yu-Hung Wang, MD^1,2*, Dorothée Selimoglu-Buet, PhD^3*, Carmelo Gurnari, MD, PhD⁴, Andres Jerez, MD, PhD^5*, Andrius Zucenka, MD^6,7, Chi-Yuan Yao, MD^8*, Chien-Chin Lin, MD, PhD^8*, Hsin-An Hou, M.D.; Ph.D.², Wen-Chien Chou, MD, PhD⁸, Hwei-Fang Tien, MD, PhD⁹, Jaroslaw Maciejewski¹⁰, Eric Solary, MD^11*, Kiran Batta, PhD¹² and Daniel H Wiseman, MB ChB PhD^12*

¹Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom
²Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
³Université Paris-Sud, Villejuif, FRA
⁴Cleveland Clinic Foundation, Cleveland, OH
⁵Hospital Morales Meseguer, Murcia, Murcia, ESP
⁶Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania
⁷Hematology and Oncology Department, Faculty of Medicine, Vilnius University, Vilnius, Lithuania
⁸Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan
⁹Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
¹⁰Taussig Cancer Center, Cleveland, OH
¹¹Inserm UMR866, Villejuif Cedex, France
¹²Division of Cancer Sciences, The University of Manchester, Manchester, United Kingdom

Evan C. Chen, MD¹, Yiwen Liu, MS^2*, Hayden L. Bell, PhD^3*, Ilene A. Galinsky, MSN, ANP-C¹, Marlise R. Luskin, MD¹, Eric S. Winer, MD¹, Maximilian Stahl, MD⁴, Rahul Vedula, MD⁵, Virginia O. Volpe, MD¹, Daniel J. DeAngelo, MD, PhD¹, Karen Quillen, MD, MPH⁶, Jeremy Ryan, MS^3*, Emma-Jayne Minihane, PhD^3*, Matthew Hersch, BA^3*, Rebecca Leonard^1*, Donna S. Neuberg, ScD⁷, Richard M. Stone, MD⁸, Anthony G. Letai³, Andrew A. Lane, MD, PhD¹ and Jacqueline S. Garcia, MD¹

¹Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
²Data Science, Dana-Farber Cancer Institute, Boston, MA
³Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
⁴Dana Farber Cancer Institute, Boston, MA
⁵Medical Oncology, Dana-Farber Cancer Institute, Stoneham, MA
⁶Beth Israel Deaconess Medical Center, Boston, MA
⁷Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
⁸Dana-Farber Cancer Institute, Boston, MA

Sven De Pourcq, MSc^1,2*, Elena Tofacchi, MSc^2,3*, Marco Gabriele Raddi, MD^3*, Giorgio Mattiuz, PhD^3*, Luca Rigodanza, MD^3*, Angela Consagra, MD^3* and Valeria Santini, MD⁴

¹MDS Unit, Department of Experimental and Clinical Medicine, University of Florence, Firenze, Italy
²Department of Medical Biotechnologies, University of Siena, Siena, Italy
³MDS Unit, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
⁴MDS Unit, Hematology, DMSC, AOU Careggi, University of Florence, Florence, Italy

Tariq Kewan, MD¹, Luisa Ladel, MD^2*, Ahmad Kiwan, MD¹ and Lourdes M Mendez, MD, PhD^3*

¹Department of Internal Medicine, Section of Hematology, Yale University, New Haven, CT
²Yale University, New Haven, CT
³Section of Hematology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT

Bo Wan, MD¹, Shabbir MH Alibhai, MD, MSc^2*, Lisa Chodirker, MD FRCPC^3*, Lee Mozessohn, MD⁴, Michelle Geddes, MD⁵, Nancy Zhu, MD, FRCPC^6*, Amy Trottier, MD, MSc, FRCPC⁷, Eve St-Hilaire, MD, FRCP^8*, Nicholas Finn, BSc, MD^9*, Brian Leber, MD¹⁰, Dina Khalaf, MSc, MBBS¹¹, Grace Christou, MD, MSc, FRCPC^12*, Mitchell Sabloff, MSc, MD, FRCPC¹³, Heather A Leitch, MD, PhD¹⁴, April Shamy, MD¹⁵, Karen Yee, MD, FRCPC^16*, John M. Storring, MDCM, FRCPC¹⁷, Thomas J. Nevill, MD, FRCPC¹⁸, Brett L. Houston, MD, PhD¹⁹, Mohamed Elemary, MD, MSc, PhD^20*, Robert Delage, MD, MSc²¹, Anne Parmentier, BA^22*, Mohammad Siddiqui^23*, Alexandre Mamedov, PhD^4*, Liying Zhang, PhD^4* and Rena Buckstein, MD, FRCPC³

¹University of British Columbia, Vancouver, BC, Canada
²Department of Supportive Care, Princess Margaret Cancer Centre - University Health Network, Toronto, Canada
³Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
⁴Sunnybrook Health Sciences Centre, Toronto, ON, Canada
⁵Tom Baker Cancer Centre, University of Calgary, Calgary, AB, Canada
⁶Clinical Assistant Professor Division of Hematology, Department of Medicine, University of Alberta, Edmonton, AB, Canada
⁷Hematology, Queen Elizabeth II Health Sciences Centre, Halifax, NS, Canada
⁸Hematology/Oncology, Dr. Georges-L-Dumont University Centre, Moncton, NB, CAN
⁹Hematology/oncology, Dr. Georges-L-Dumont University Centre, Moncton, CAN
¹⁰Division of Hematology, Juravinski Cancer Center, Hamilton, ON, Canada
¹¹Department of Oncology, McMaster University, Hamilton, ON, Canada
¹²Division of Hematology, The Ottawa Hospital, Ottawa, ON, Canada
¹³Ottawa Hospital Research Institute, Ottawa, ON, Canada
¹⁴Hematology, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada
¹⁵Jewish General Hospital, McGill University, Montreal, QC, CAN
¹⁶Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada
¹⁷McGill University Health Centre, Montreal, QC, Canada
¹⁸Division of Hematology, Department of Medicine, University of British Columbia, Vancouver, Canada
¹⁹University of Manitoba, Winnipeg, MB, CAN
²⁰Provincial Hematology and Blood and Marrow Transplant Program, Saskatchewan Cancer Agency, University of Saskatchewan, Saskatoon, SK, Canada
²¹Quebec CML-MPN Research Group, Montreal, QC, Canada
²²Sunnybrook Health Sciences, Odette Cancer Center, Toronto, ON, Canada
²³Hematology Clinical Trials, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Canada

Kelly S. Chien, MD¹, Ziyi Li, PhD^2*, Luca Lanino, MD³, Najla H. Al Ali, Ms^4*, Samuel Urrutia, MD⁵, Rashmi Kanagal-Shamanna, MD⁶, Ahmed Abdelhakeem, MD^1*, Tareq Abuasab, MD^1*, Emmanuel Almanza, MD^1*, Georgina Gener-Ricos, MD^1*, Alex Bataller, MD, PhD^1*, Alexandre Bazinet, MD^1*, Alessia Campagna, MD^7*, Giulia Maggioni, MD^7*, Eric Padron, MD⁸, Zhuoer Xie, MD, MS⁸, Guillermo Montalban-Bravo, MD¹, Nicholas J. Short, MD¹, Elias Jabbour, MD¹, Tapan M. Kadia, MD¹, Farhad Ravandi, MBBS⁹, Gautam Borthakur, MD¹⁰, Danielle Hammond, MD¹, Mahesh Swaminathan, MD¹, Koji Sasaki, MD¹, Xiao Qin Dong^1*, Sherry Pierce, BSN, BA^1*, David Sallman, MD⁸, Hagop M. Kantarjian, MD¹, Matteo Giovanni Della Porta, MD^7*, Guillermo Garcia-Manero, MD¹ and Rami S. Komrokji, MD⁸

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
³IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy
⁴Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁵Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
⁶Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy
⁸Department of Malignant Hematology, H Lee Moffitt Cancer Center, Tampa, FL
⁹Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX
¹⁰Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Jan Philipp Bewersdorf, MD¹, Vanessa Hasle^2*, Rory M. Shallis, MD³, Ethan G. Thompson, PhD^2*, Daniel Lopes De Menezes, PhD^4*, Shelonitda Rose², Isaac W. Boss^2*, Lourdes Mendez, MD^5*, Nikolai A. Podoltsev, MD, PhD⁶, Maximilian Stahl, MD⁷, Tariq Kewan, MD⁸, Stephanie Halene, MD⁹, Torsten Haferlach, MD¹⁰, Brian Fox^2* and Amer M. Zeidan, MBBS, MHS¹¹

¹Department of Medicine, Section of Hematology, Yale University, New Haven, CT
²Bristol Myers Squibb, Princeton, NJ
³Department of Internal Medicine, Section of Hematology, Yale School of Medicine - Yale Cancer Center, Killingworth, CT
⁴Translational Medicine, Hematology, Bristol Myers Squibb, San Francisco, CA
⁵Department of Internal Medicine, Section of Hematology, Yale School of Medicine - Yale Cancer Center, New Haven, CT
⁶Department of Internal Medicine, Section of Hematology, Yale University School of Medicine and Yale Cancer Center, Madison, CT
⁷Dana Farber Cancer Institute, Boston, MA
⁸Department of Internal Medicine, Section of Hematology, Yale University, New Haven, CT
⁹Department of Internal Medicine, Section of Hematology, Yale University School of Medicine and Yale Cancer Center, New Haven, CT
¹⁰MLL Munich Leukemia Laboratory, Munich, Germany
¹¹Section of Hematology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT

Saubia Fathima, MD¹, Ali Alsugair, MBBS², Anuya A. Natu^1*, Clifford M. Csizmar, MD, PhD³, Mark Gurney, MB, BCh, BAO^4*, Terra L. Lasho, PhD¹, Christy Finke, BS^4*, Abhishek A. Mangaonkar, MBBS¹, Kaaren K. Reichard, MD⁵, Rong He, MD⁶, Animesh D. Pardanani, MBBS, PhD³, Naseema Gangat, MBBS⁴, Mrinal M. Patnaik, MD, MBBS¹ and Ayalew Tefferi, MD⁴

¹Mayo Clinic, Rochester, MN
²Department of Hematology, Mayo Clinic, Rochester, MN
³Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN
⁴Division of Hematology, Mayo Clinic, Rochester, MN
⁵Department of Pathology, Mayo Clinic, Rochester, MN
⁶Division of Hematopathology, Mayo Clinic, Rochester, MN

Ines Zugasti^1,2*, Samuel Urrutia^3,4*, Eduardo Edelman Saul, MD⁴, Georgina Daher-Reyes^5*, Mohammed Asim Amjad^6*, Jia Wu^7*, Koji Sasaki, MD⁸, Ajay Sheshadri^6* and Guillermo Garcia-Manero, MD⁸

¹GESMD (Grupo Español de Sindromes Mielodisplasicos), Madrid, Spain
²Hematology Department, Hospital Clinic de Barcelona, ICMHO, Barcelona, Spain
³Division of Oncology, Washington University School of Medicine in St. Lous, Saint Louis
⁴Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Princes Margaret Cancer Center, Toronto, ON, CAN
⁶Department of Pulmonary Medicine, Division of Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷Department of Imaging Physics, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
⁸Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Alfonso Molina, MD, MPH¹, Vishesh Khanna, MD², Rong Lu, Phd^3*, Henning Stehr, PhD^4*, Brent Tan, MD, PhD^4* and Peter L. Greenberg, MD⁵

¹Department of Medicine, Division of Hematology, Stanford University School of Medicine, San Carlos, CA
²Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, CA
³Department of Medicine, Quantitative Sciences Unit, Stanford University School of Medicine, Stanford, CA
⁴Department of Pathology, Stanford University School of Medicine, Stanford, CA
⁵Stanford Cancer Center, Stanford, CA

Ziad Abuhelwa, MD, MPH^1,2, Najla H. Al Ali, Ms^3*, Zhuoer Xie, MD, MS⁴, Onyee Chan, MD^2*, Seongseok Yun, MD, PhD³, Andrew T. Kuykendall, MD³, Alison R. Walker, MD, MBA, MPH⁵, Jeffrey E Lancet, MD³, Eric Padron, MD³, David Sallman, MD³ and Rami S. Komrokji, MD³

¹Morsani College of Medicine, University of South Florida, Tampa, FL
²H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
³Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁴Department of Malignant Hematology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁵Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Wesley Chapel, FL

Rami S. Komrokji, MD¹, Valeria Santini, MD², Uwe Platzbecker, MD³, Koen Van Eygen, MD⁴, Maria Diez-Campelo, MD, PhD^5*, Raquel De Paz, MD, PhD^6*, Guillermo Sanz, MD, PhD^7,8,9, Sylvain Thépot, MD^10*, Maciej Kaźmierczak, MD, PhD^11*, Esther Natalie Oliva, MD¹², Mikkael A. Sekeres, MD¹³, Pierre Fenaux, MD¹⁴, Yazan F. Madanat, MD¹⁵, Michael R. Savona, MD¹⁶, Jennifer Riggs, MPH^17*, Souria Dougherty, MBA^17*, Ashley Lennox, PhD^17*, Qi Xia, PhD^17*, Libo Sun, PhD^17*, Tymara Berry, MD^17* and Amer M. Zeidan, MD¹⁸

¹Moffitt Cancer Center, Tampa, FL
²MDS Unit, Hematology, AOUC, University of Florence, Florence, Italy
³Department for Hematology, Cell Therapy, Hemostaseology and Infectious Diseases, University of Leipzig Medical Center, Leipzig, Germany
⁴AZ Groeninge, Kortrijk, Belgium
⁵Hospital Clínico Universitario de Salamanca, Salamanca, Spain
⁶Servicio de Hematología y Hemoterapia, Hospital Universitario La Paz, Madrid, Spain
⁷CIBERONC, ISCIII, Madrid, Spain
⁸Health Research Institute La Fe, Valencia, Spain
⁹Hematology Department, Hospital Universitari i Politècnic La Fe, Valencia, Spain
¹⁰Centre Hospitalier Universitaire d'Angers, Angers, France
¹¹Poznań University of Medical Sciences, Poznań, Poland
¹²Hematology Unit, Grande Ospedale Metropolitano BMM, Reggio Calabria, Reggio Calabria, Italy
¹³Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL
¹⁴Hôpital Saint-Louis, Université de Paris 7, Paris, France
¹⁵Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX
¹⁶Vanderbilt University Medical Center, Nashville, TN
¹⁷Geron Corporation, Foster City, CA
¹⁸Yale School of Medicine, Smilow Cancer Hospital at Yale New Haven, New Haven, CT

Shuhying Tan, FRACP, FRCPA, MBBS^1*, Montserrat Arnan, MD, PhD^2*, Lynette C.Y. Chee, MBBS, PhD, FRACP, FRCPA³, Thomas Cluzeau, MD, PhD⁴, Maria Diez-Campelo, MD, PhD^5*, Aristoteles Giagounidis, MD⁶, Devendra Hiwase, MD, MBBS, PhD, FRACP, FRCPA⁷, David M Ross, MD, PhD, FRACP, FRCPA^8*, Mikkael A. Sekeres, MD⁹, David Valcarcel, MD, PhD¹⁰, Bhavna Patel-Shah^11*, Ming Yang, PhD^11*, Ying Jiang, PhD, MBA^11*, Jiani Yin, PhD^11*, Suresh Bobba^11*, Montagu Hankin, MSc^11*, Chris Materna, MSc^11*, Christine Graham, PhD^11*, Sanjay Thamake, PhD, MBA^11*, Christopher Rovaldi, MSc^11*, Dena Grayson, MD, PhD^11* and Jen L. Salstrom, MD, PhD¹¹

¹St. Vincent's Institute of Medical Research, East Melbourne, Vic, AUS
²Hematology Department. Institut Català d’Oncologia, Hospital Duran i Reynals. Institut d’Investigació Biomèdica de Bellvitge (IDIBELL). Universitat de Barcelona, Hospitalet de Llobregat, Barcelona, Spain
³Department of Clinical Haematology and Bone Marrow Transplant Service, The Royal Melbourne Hospital, Parkville, Australia
⁴Department for Clinical Hematology, Nice University Hospital, Nice, Provence Alpes Cote d'Azur, France
⁵Hospital Clínico Universitario de Salamanca, Salamanca, Spain
⁶Clinic for Hematology, Oncology and Palliative Care Marien Hospital Düsseldorf, Dusseldorf, Germany
⁷Royal Adelaide Hospital, Adelaide, SA, Australia
⁸Royal Adelaide Hospital and SA Pathology, Adelaide, SA, Australia
⁹Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL
¹⁰Department of Hematology and Oncology, Hospital Universitario Vall d'Hebron, Barcelona, Spain
¹¹Kero's Therapeutics, Lexington

Sirilak Sutthinont^1*, Nisa Makkruasi, MD^2*, Anothai Chintabanyat, M.D.^3*, Thanawat Rattanathammethee, M.D.^4*, Ponlapat Rojnuckarin, MD^5,6, Wiroj Jiamjarasrangsi, MD^1* and Chantana Polprasert, MD^5,7*

¹Department of Preventive and Social Medicine, Faculty of Medicine, Chulalongkorn Universityand King Chulalongkorn Memorial Hospital, Bangkok, Thailand
²Division of Hematology, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok, Thailand
³Division of Hematology, Department of Medicine, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand
⁴Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
⁵Division of Hematology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand
⁶Center of Excellence in Translational Hematology, Chulalongkorn University, Bangkok, Thailand
⁷Center of Excellence in Translational Hematology, Faculty of Medicine, Chulalongkorn University, Bangkok, Bangkok, Thailand

Anuya A. Natu, MBBS^1*, Clifford M. Csizmar, MD, PhD¹, Terra L. Lasho, PhD², Rashmi Kanagal-Shamanna, MD³, Sanam Loghavi, MD⁴, Alexandre Bazinet, MD^5*, Kelly S. Chien, MD⁶, Danielle Hammond, MD⁷, Christy Finke, BS^1*, Aref Al-Kali, MD¹, Hassan B Alkhateeb, MD^1*, Naseema Gangat, MBBS¹, Abhishek A. Mangaonkar, MBBS², Antoine N. Saliba, MD¹, Ayalew Tefferi, MD¹, Guillermo Garcia-Manero, MD⁷, Hagop Kantarjian, MD⁷, Guillermo Montalban-Bravo, MD⁷ and Mrinal M. Patnaik, MD, MBBS¹

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Mayo Clinic, Rochester, MN
³Department of Hematopathology, The University of Texas M. D. Anderson Cancer Center, Houston, TX
⁴Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston
⁶Department of Leukemia, MD Anderson, Houston, TX
⁷Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Kevin Hung, MBBS, FRACP, FRCPA¹, Aref Al-Kali, MD², Carla Toop, PhD^1*, Mrinal M. Patnaik, MD, MBBS², Zoe Price, BSc (Hons)^3*, Taxiarchis Kourelis, MD², Daniel Thomas, MBBS, PhD^1,3,4*, Morie A. Gertz, MD², Hossein Anani^4*, Wilson I. Gonsalves, MD⁵, Chung Hoow Kok, PhD, BSc⁶, Ayalew Tefferi, MD², Devendra Hiwase, MD, MBBS, PhD, FRACP, FRCPA^1,3,4 and Mithun V Shah, M.D., Ph.D.²

¹Department of Haematology, Central Adelaide Local Health Network, Adelaide, SA, Australia
²Division of Hematology, Mayo Clinic, Rochester, MN
³South Australian Health and Medical Research Institute, Adelaide, SA, Australia
⁴Adelaide Medical School, The University of Adelaide, Adelaide, SA, Australia
⁵Division of Hematology, Mayo School of Graduate Medical Education, Rochester, MN
⁶Centre for Cancer Biology and SA Pathology, Adelaide, Australia

Guillermo Garcia-Manero, MD¹, Yazan F Madanat, MD², Mikkael A. Sekeres, MD³, Hetty E. Carraway, MD, MBA⁴, Mike Cusnir, MD⁵, James McCloskey, MD⁶, Kiran Naqvi, MD, MPH⁷, Gary J. Schiller, MD⁸, Lucy Yan, MD, PhD^9*, Toufigh Gordi, PhD, MBA^9*, Lisa Rojkjaer, MD¹⁰ and Lewis R. Silverman, MD¹¹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX
³Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
⁴Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
⁵Mount Sinai Comprehensive Cancer Ctr., Miami Beach, FL
⁶John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ
⁷Department of Medicine, Division of Hematology Oncology, Chao Family Comprehensive Cancer Center,, University of California Irvine Health, Orange, California, USA, Orange, CA
⁸David Geffen School of Medicine, UCLA, Los Angeles, CA
⁹Rigel Pharmaceuticals, Inc., South San Francisco, CA
¹⁰Rigel, Rancho Santa Fe, CA
¹¹Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY

Devendra Hiwase, MD, MBBS, PhD, FRACP, FRCPA^1,2,3, Zoe Price, BSc (Hons)^1*, Chung How Kok, BSc, PhD^4,5*, Monika Kutyna, PhD^1,3*, Deepak Singhal, MBBS, MD, FRACP, FRCPA^3*, Naranie Shanmuganathan, MBBS, PhD, FRACP, FRCPA³, Lesley Rawlings^4*, David M Ross, MD, PhD, FRACP, FRCPA^3,6*, David T Yeung, MBBS, PhD, BSc, FRACP, FRCPA^1,2,3, Anna Brown, PhD^4,5*, Christopher N. Hahn, PhD^4,5*, Lucy A. Godley, MD, PhD⁷, Caner Saygin, MD⁸ and Hamish S Scott, PhD^4,5

¹South Australian Health and Medical Research Institute, Adelaide, SA, Australia
²University of Adelaide, Adelaide, SA, Australia
³Department of Haematology, Central Adelaide Local Health Network, Adelaide, SA, Australia
⁴SA Pathology, Adelaide, SA, Australia
⁵University of South Australia, Adelaide, SA, Australia
⁶Flinders University, Adelaide, Australia
⁷Northwestern University, Chicago, IL
⁸University of Chicago, Chicago, IL

Sangeetha Venugopal, MD, MS¹, Michael Otterstatter, PhD^2*, Amy E. DeZern, MD, MHS³, Matthew J. Walter, MD⁴, James M. Foran, MD⁵, Rafael Bejar, MD, PhD⁶, Tareq Al Baghdadi, MD^7*, H. Joachim Deeg, MD⁸, Rami S. Komrokji, MD⁹, Gregory A Abel, MD, MPH¹⁰, R. Coleman Lindsley, MD¹⁰, Jane Jijun Liu^11*, Yazan F Madanat, MD¹², Lynn C. Moscinski, MD¹³, Wael Saber, MD, MS¹⁴, Jennifer Vidrine^15*, Damon J. Vidrine^15*, Ling Zhang, MD¹⁶, Christine Borchert, BSc^2*, Seth Sherman, PhD^2*, Nancy DiFronzo, PhD^17*, Nancy Gillis, PhD¹⁸ and Mikkael A. Sekeres, MD¹

¹Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL
²The Emmes Company, LLC, Rockville, MD
³Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD
⁴Washington University In St. Louis, Saint Louis, MO
⁵Division of Hematology & Medical Oncology, Mayo Clinic, Jacksonville, FL
⁶Aptose Biosciences, La Jolla, CA
⁷IHA Hematology Oncology, Ypsilanti, MI
⁸Fred Hutchinson Cancer Research Center, Seattle, WA
⁹Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
¹⁰Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
¹¹Illinois CancerCare, Peoria, IL
¹²Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX
¹³Department of Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
¹⁴Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, WI
¹⁵Moffitt Cancer Center, Tampa, FL
¹⁶Department of Pathology and Laboratory Medicine, H. Lee Moffitt Cancer and Research Institute, Tampa, FL
¹⁷Division of Blood Diseases & Resources, The National Heart, Lung, and Blood Institute, Bethesda, MD
¹⁸Department of Cancer Epidemiology, Moffitt Cancer Center and Research Institute, Tampa, FL

James T England, MD, MSc, FRCPC¹, Liying Zhang, PhD^2*, Karen Yee, MD, FRCPC^3*, Michelle Geddes, MD⁴, Nancy Zhu, MD, FRCPC^5*, April Shamy, MD⁶, Heather A Leitch, MD, PhD⁷, Mitchell Sabloff, MSc, MD, FRCPC⁸, Grace Christou, MD, MSc, FRCPC^9*, Brett L. Houston, MD, PhD^10,11, Brian Leber, MD¹², Dina Khalaf, MSc, MBBS¹³, Eve St-Hilaire, MD, FRCP^14*, Nicholas Finn, BSc, MD^15*, Thomas J. Nevill, MD, FRCPC¹⁶, Amy Trottier, MD, MSc, FRCPC¹⁷, John M. Storring, MDCM, FRCPC¹⁸, Mohamed Elemary, MD, MSc, PhD^19*, Robert Delage, MD, MSc²⁰ and Rena Buckstein, MD, FRCPC¹

¹Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
²Sunnybrook Health Sciences Centre, Toronto, ON, Canada
³Princess Margaret Cancer Centre / University Health Network, Toronto, ON, Canada
⁴Tom Baker Cancer Centre, University of Calgary, Calgary, AB, Canada
⁵Clinical Assistant Professor Division of Hematology, Department of Medicine, University of Alberta, Edmonton, AB, Canada
⁶Jewish General Hospital, McGill University, Montreal, QC, CAN
⁷Hematology, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada
⁸Ottawa Hospital Research Institute, Ottawa, ON, Canada
⁹Division of Hematology, The Ottawa Hospital, Ottawa, ON, Canada
¹⁰Cancercare Manitoba, Winnipeg, MB, CAN
¹¹University of Manitoba, Winnipeg, MB, CAN
¹²Division of Hematology, Juravinski Cancer Center, Hamilton, ON, Canada
¹³Juravinski Cancer Centre, McMaster University, Hamilton, ON, Canada
¹⁴Hematology/Oncology, Dr. Georges-L-Dumont University Centre, Moncton, NB, CAN
¹⁵Hematology/oncology, Dr. Georges-L-Dumont University Centre, Moncton, CAN
¹⁶Department of Medicine, Division of Hematology, University of British Columbia, Leukemia Bone Marrow Transplant Program of British Columbia and Vancouver General Hospital, Vancouver, BC, Canada, Vancouver, BC, CAN
¹⁷Hematology, Queen Elizabeth II Health Sciences Centre, Halifax, NS, Canada
¹⁸McGill University Health Centre, Montreal, QC, Canada
¹⁹Provincial Hematology and Blood and Marrow Transplant Program, Saskatchewan Cancer Agency, University of Saskatchewan, Saskatoon, SK, Canada
²⁰Integrated Cancer Center, CHU de Québec, Laval University, Quebec, QC, Canada

Amy Song^1*, Richard Shao^2*, Lynn C. Moscinski, MD³, Julie Li, MD^3*, Mohammad Omar Hussaini, MD^4*, Le Wang, MD, PhD⁵ and Hailing Zhang, MD^3*

¹Department of Internal Medicine, Columbia University Irving Medical Center, Princeton, NJ
²The University of Central Florida College of Medicine, Orlando, FL
³Department of Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁴Department of Pathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁵Guthrie Clinic Cancer Center Robert Packer Hospital, Sayre, PA

Jorge E. Cortes, MD¹, Justin M. Watts, MD², Eunice S. Wang, MD³, Jay Yang, MD⁴, Shira N. Dinner, MD⁵, Maria R. Baer, MD⁶, Gail J. Roboz, MD⁷ and William B. Donnellan, MD⁸

¹Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA
²Sylvester Cancer Center, University of Miami Miller School of Medicine, Miami, FL
³Leukemia Service, Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY
⁴Department of Oncology, Karmanos Cancer Institute/Wayne State University, Detroit, MI
⁵Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL
⁶Department of Medicine, University of Maryland School of Medicine, Baltimore, MD
⁷Division of Hematology and Medical Oncology, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY
⁸Sarah Cannon Research Institute, Tennessee Oncology, Nashville, TN

Ian M. Bouligny, MD¹, Guillermo Montalban-Bravo, MD¹, Koji Sasaki, MD¹, Naval Daver, MD², Elias Jabbour, MD¹, Yesid Alvarado Valero, MD¹, Courtney D. DiNardo, MD, MSc³, Farhad Ravandi, MBBS⁴, Gautam Borthakur, MD⁵, Prithviraj Bose, MD⁶, Naveen Pemmaraju, MD⁷, Steven M. Kornblau, MD¹, Tapan M. Kadia, MD¹, Lucia Masarova, MD¹, Koichi Takahashi, MD, PhD⁸, Michael Andreeff, MD, PhD⁵, Alexandre Bazinet, MD^1*, Hui Yang, PhD, MD¹, Rashmi Kanagal-Shamanna, MD⁹, Chitra Hosing, MD¹⁰, Sherry Pierce, BSN, BA^1*, Meghan Anne Meyer, BSN, RN^1*, Xuelin Huang, PhD^11* and Guillermo Garcia-Manero, MD¹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²MD Anderson Cancer Center, Houston, TX
³Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
⁴Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX
⁵Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁶The University of Texas MD Anderson Cancer Center, Houston, TX
⁷Department of Leukemia, The University of Texas MD Anderson Cancer Center, Bellaire, TX
⁸Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
⁹Department of Hematopathology, The University of Texas M. D. Anderson Cancer Center, Houston, TX
¹⁰Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
¹¹Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX

Mihir Shukla, MD¹, Chinyere Okpara, MS^2*, Elaine Xiang, PharmD³, Maher Abdul Hay, MD⁴, Shella Saint Fleur-Lominy, MD, PhD⁵ and Jun Han Choi, MD⁶

¹Perlmutter Cancer Center, New York University Grossman School of Medicine/NYU Langone Health, New York, NY
²Department of Surgery, NYU Grossman Long Island School of Medicine, Mineola, NY
³NYU Langone Health, New York, NY
⁴Perlmutter Cancer Center, NYU Langone Health, New York, NY
⁵NYU Perlmutter Cancer Center, New York University Grossman School of Medicine, New York, NY
⁶NYU Langone, New York, NY

Shanawar Waris, MD^1*, Adnan Saifuddin, MD^1*, Yashan Thakkar, BS^2*, Gary Monroe, DO^1*, Zainab Fatima, MD^3*, Carl Shultz, DO^3*, Danish Safi, MD³ and Salah Ud Din Safi, MD^4*

¹Department of Internal Medicine, West Virginia University School of Medicine, Morgantown, WV
²West Virginia University School of Medicine, Morgantown, WV
³Department of Medical Oncology, West Virginia University Cancer Institute, Morgantown, WV
⁴West Virginia University Cancer Institute, Morgantown, WV

Lisa D.S. Johnson^1* and Yajia Zhang, PhD^2*

¹Biomarker Sciences and Diagnostics, Gilead Sciences Inc., Foster City, CA
²Clinical Bioinformatics and Exploratory Analysis, Gilead Sciences Inc., Foster City, CA

Yanal Alnimer, MD, MPH^1*, Reinhold Munker, MD², Ayman Qasrawi, MD³, Gregory Monohan^4*, Chait Iragavarapu^3* and Fevzi Yalniz, MD^2*

¹University of Kentucky, Tappahannock, VA
²Department of Hematology, University of Kentucky, Lexington, KY
³University of Kentucky, Lexington, KY
⁴University of Kentucky, Lexington

Anoop K Enjeti, MBBS, FRCPA, MD, MRCP^1,2,3, Suthanthirakannan Ramamoorthy, MBBS FRACP^4*, Devendra Hiwase, MD, MBBS, PhD, FRACP, FRCPA⁵, Asma Ashraf, FRACP, MBBS, FRCPA⁶, Belinda E Butcher, BSc(Hons), MBiostat, PhD, CMPP AStat^7*, Sushma Kollipara^8*, Carolyn S. Grove, MBBS, FRACP, FRCPA, PhD^9,10, Andrew H Wei, MBBS, PhD, FRACP, FRCPA^11,12 and Jake Shortt¹³

¹Department of Haematology, Calvary Mater Hospital, Waratah, NSW, Australia
²Precision Medicine Research Program, Hunter Medical Research Institute, NSW, SA, Australia
³School of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, Australia
⁴Haematology dept., Royal Darwin Hospital, Darwin, Australia
⁵Royal Adelaide Hospital, Adelaide, SA, Australia
⁶Calvary Mater Hospital, Waratah, AUS
⁷University of NSW, Sydney, Australia
⁸Australasian Leukaemia and Lymphoma Group, Melbourne, Australia
⁹School of Pathology and Laboratory Medicine, University of Western Australia, Perth, Australia
¹⁰Sir Charles Gairdner Hospital, Nedlands, Australia
¹¹Peter MacCallum Cancer Centre, Melbourne, VIC, Australia
¹²The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia
¹³Monash University and Monash Health, Melbourne, VIC, Australia