Inés Gómez Seguí^1*, Maria Cristina Pascual Izquierdo, MD, PhD^2*, Maria Eva Mingot^3*, Amanda Lopez Picado^4,5*, Guillermo Sanz, MD, PhD¹, Javier de la Rubia^1*, Ramon Salinas Argente, MD^6* and Julio Del Rio Garma, MD^7*

¹Hematology Department, Hospital Universitari i Politècnic La Fe, Valencia, Spain
²Servicio de Hematología, Hospital Universitario Gregorio Marañón, Instituto de Investigación Gregorio Marañón, Madrid, Madrid, Spain
³Servicio de Hematología, Hospital Universitario Virgen del Rocío, Malaga, Spain
⁴Facultad de Medicina, Universidad de Deusto, Bilbao, Spain
⁵Sociedad Española de Hematologia, Madrid, Spain
⁶Universidad Internacional de Cataluña, Barcelona, Spain
⁷Hospital Clinico Santiago de Compostela, Coruña, ESP

Alicia Cruz Gómez, MD^1*, María Martínez Rodríguez^2*, Andrés Felipe Melo Arias^3*, Clara Fernández Arias^4*, Olatz Olabarri Etxebarria^5*, Laura Sánchez Calvo^6*, Maria José de la Osa Velacoracho^6*, Kenneth Herrera Robles^7*, Ana Tobalina García^8*, Stefania Carvajal Altamiranda^9*, Jorge Martínez Nieto^10*, Ana Villegas, MD³, Alejandro Sánchez Saito^11*, Miguel Gómez Álvarez^3*, Sara Ferrer^10*, Rafael López del Amo^3*, Paloma Ropero Gradilla^3*, Celina Benavente Cuesta^3*, Fernando Ataulfo González Fernández^3* and Gonzalo Del Campo Balguerías, MD^3*

¹Hospital Universitario de Getafe, Madrid, Spain
²Hospital Universitario de Móstoles, Madrid, Spain
³Hospital Clínico San Carlos, Madrid, Spain
⁴Clínica Universitaria de Navarra, Pamplona, Spain
⁵Hospital Galdakao, Bilbao, Spain
⁶Hospital Universitario de la Princesa, Madrid, Spain
⁷Hospital Clínico Universitarios de Valladolid, Valladolid, AL, ESP
⁸Hospital Universitario Marqués de Valdecilla, Santander, Spain
⁹Hospital Universitario de Segovia, Segovia, Spain
¹⁰Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain
¹¹Hospital Universitario Infanta Leonor, Madrid, Spain

Paul Coppo, MD^1*, Marie Scully, MD², Agathe Nevière^3*, Pauline Le Nouveau^3*, Prerna Patel^4*, Alaeddine Sidhom^5*, Srushhti Trivedi^6*, Rachel Chu^7*, Da Eun Ahn^4*, Gabriela Marcheva^8*, Divyesh Thakker^9*, Gaye Siliman^10* and Alix Arnaud^8*

¹Department of Hematology, Reference Center for Thrombotic Microangiopathies, Saint-Antoine University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France
²University College London, London, ENG, United Kingdom
³HEMA, Amaris Consulting, Nantes, France
⁴HEMA, Amaris Consulting, London, United Kingdom
⁵HEMA, Amaris Consulting, Barcelona, Spain
⁶HEMA, Amaris Consulting, Toronto, ON, Canada
⁷HEMA, Amaris Consulting, Montreal, QC, Canada
⁸HEVA, Sanofi, Boston, MA
⁹Sanofi Global Hub, Sanofi, Hyderabad, Telangana, India
¹⁰HEVA, Sanofi, Mississauga, ON, Canada

Dorothee Diogo, PhD^1*, Pinghai Zhang^1*, Wolf-Achim Hassenpflug, MD^2*, Björn Mellgård¹, Parth Patwari, MD, PhD^1*, Wei Qu^3* and Linda T. Wang^1*

¹Takeda Development Center Americas, Inc., Cambridge, MA
²Department of Pediatric Hematology and Oncology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany
³Takeda Pharmaceuticals Company Limited, Fujisawa, Japan

Roman R. Schimmer, MD^1*, Jana Van Den Berg, MD^2*, Marissa Schraner, PhD³, Alice Trinchero, MD^1*, Andreas Holbro, MD², Johanna A. Kremer Hovinga, MD⁴ and Jan-Dirk Studt, MD^1*

¹Department for Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland
²Division of Hematology, University Hospital Basel, Basel, Switzerland
³Department of Hematology and Central Hematology Laboratory, Inselspital Bern, University Hospital Bern and University of Bern, Bern, Switzerland
⁴Department of Hematology and Central Hematology Laboratory, Inselspital Bern, Bern University Hospital, University of Bern, Bern, Switzerland

Mari Thomas^1,2*, Imogen Buckle^3*, Adela Constantinescu-Bercu, PhD^4*, Rens De Groot, PhD^5*, Arshia Latif^3*, Sabina McCann^6* and Marie Scully, MD^7,8

¹Department of Haematology, University College London Hospital, London, ENG, United Kingdom
²Cardiometabolic Program, National Institute for Health Research UCLH/UCL Biomedical Research Centre, London, United Kingdom
³UCL, London, United Kingdom
⁴UCL, London, GBR
⁵Institute Cardiovascular Science, UCL, London, GBR
⁶Special Coagulation, Health Services Laboratories, London, London, GBR
⁷University College London, London, ENG, United Kingdom
⁸Department of Haematology, University College London Hospitals, Cardiometabolic Program, National Institute for Health Research UCLH/UCL Biomedical Research Centre, London, United Kingdom

Praveen Gounder^1*, Louisa Keogh^2*, William Lester^3*, Amanda Clark^4*, Joost Vanveen^5*, Tina Dutt^6*, Michael Desborough, BSc, DPhil, FRCP, FRCPath^7*, Joannes Hermans^8*, Alice Taylor^9* and Marie Scully, MD¹⁰

¹Haematology Department, University College London Hospital, London, United Kingdom
²Hematology Department, University College London Hospital, London, United Kingdom
³University Hospital NHS Foundation Trust Birmingham, Birmingham, GBR
⁴Haematology Department, University Hospital Bristol, Bristol, United Kingdom
⁵Haemophilia & Thrombosis Centre, Royal Hallamshire Hospital, Sheffield, United Kingdom
⁶Liverpool University Hospitals NHS Foundation Trust, Liverpool, United Kingdom
⁷NHS Blood and Transplant, John Radcliffe Hospital, Oxford, United Kingdom
⁸Haematology Department, Nottingham University Hospital, Nottingham, United Kingdom
⁹Great Ormond Street Hospital for Children Foundation Trust, London, United Kingdom
¹⁰University College London, London, ENG, United Kingdom

Munjal Patel^*, Björn Mellgård, Luying Pan^*, Linda T. Wang^*, Shan Xiao^* and Parth Patwari, MD, PhD^*

Takeda Development Center Americas, Inc., Cambridge, MA