Alexander S. Steemers^1,2*, Vera M Poort, MSc^1,2*, Ruben Van Boxtel, PhD^1,2*, Friederike Meyer-Wentrup, MD, PhD^3*, Rico Hagelaar, MSc^1,2* and Niels M Groenen^4*

¹Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands
²Oncode Institute, Utrecht, Netherlands
³Pincess Máxima Centrum For Pediatric Oncology, Utrecht, NLD
⁴Prinses Maxima Centrum, Utrecht, Netherlands

Hudan Liu, PhD

Wuhan University, Wuhan, China

María Mercedes Debernardi, BSc^1*, Lucero Alvarado^2*, Ingrid Souza^3*, Graciela Alicia Cremaschi, PhD^2*, Alejandro Correa, Dr.^3* and Florencia Cayrol, PhD²

¹BIOMED-UCA-CONICET, Capital Federal, AL, Argentina
²BIOMED-UCA-CONICET, Buenos Aires, Argentina
³Instituto Carlos Chagas, Curitiba, Brazil

Zhenhua Chen, PhD^1*, Lu Yang, PhD^2*, Lillian Sau^3*, Zunsong Hu, PhD⁴, Meiling Chen^3*, Chengwu Zeng, PhD^5*, Chao Shen, PhD^1*, Ying Qing, PhD^3*, Yuan Che^3*, Dong Wu, PhD^3*, Tingting Tang^3*, Zhaoxu Xu^3*, Xin He, MD^6*, Lianjun Zhang, PhD^7*, Pu Cheng^8*, Hengyou Weng, PhD^9*, Huilin Huang, PhD^10*, Zhaohui Gu, PhD⁴, Gang Xiao, PhD^11*, Xiaolan Deng, PhD^3* and Jianjun Chen, PhD³

¹Department of Systems Biology, City of Hope, Arcadia, CA
²Department of Systems Biology, City of Hope National Medical Center, Duarte, CA
³Department of Systems Biology, City of Hope, Monrovia, CA
⁴City of Hope, Duarte, CA
⁵Department of Systems Biology, Beckman Research Institute, City of Hope, Monrovia, CA
⁶Department of Hematological Malignancies Translational Science, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA
⁷Department of Hematologic Malignancies Translational Science, Gehr Family Center for Leukemia Research, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA
⁸Zhejiang University School of Medicine, Hangzhou, China
⁹Guangzhou Laboratory, Guangzhou, China
¹⁰Sun Yat-sen University Cancer Center, Guangzhou, China
¹¹School of Medicine, Zhejiang University, Hangzhou, China

Chih-Chao Hsu^1*, Junfei Zhao^1*, Ann Polonskaia^1*, Chad C. Bjorklund^1*, Maria Ortiz Estevez^2*, Anita K. Gandhi, PhD³ and Patrick R. Hagner, PhD^1*

¹Bristol Myers Squibb, Summit, NJ
²Bristol Myers Squibb, Sevilla, Spain
³Hematology, Translational Medicine, Bristol Myers Squibb, Summit, NJ

Rahul S Bhansali, MD^1,2, Nicholas Aboreden, BS, MS^1*, Siqing Wang, PhD^1*, Cheryl A. Keller, PhD^3*, Belinda M. Giardine^3*, Ross C. Hardison, PhD^3* and Gerd A. Blobel, MD, PhD¹

¹Department of Pediatrics (Hematology), Children's Hospital of Philadelphia, Philadelphia, PA
²Department of Medicine, Division of Hematology/Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA
³Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA

Marouscha De Vries, BSc^1*, Silvia Vicenzi, PhD², Geena Ildefonso, PhD^3*, Brin Rosenthal, PhD^4* and Leslie A Crews, PhD⁵

¹Moores Cancer Center, University of California San Diego, San Diego, CA
²Moores Cancer Center, UNIVERSITY CALIFORNIA, SAN DIEGO, La Jolla, CA
³Center for Computational Biology and Bioinformatics (CCBB), University of California, San Diego, San Diego, CA
⁴Center for Computational Biology and Bioinformatics (CCBB), University of California San Diego, San Diego, CA
⁵Division of Regenerative Medicine, Department of Medicine, Moores Cancer Center and Sanford Stem Cell Institute, University of California San Diego, La Jolla, CA

Jinhua Liang, PhD^1*, Weiting Wang, MD^2*, Ziwen Duan, MD^2*, Tong-Yao Xing, MD^2*, Hao-Rui Shen^2*, Hua Yin^3*, Li Wang^3*, Jianyong Li, MD⁴ and Xu Wei, MD, PhD³

¹Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, NANJING, China
²Department of Hematology, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
³Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
⁴First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China

Gunjan Sharma^1*, Matin Gutierrez^2*, Anthony E. Jones^3*, Zachary T. Neeb^2*, Amy Rios^3*, Amit K. Jaiswal, PhD¹, Michelle L. Thaxton^1*, Tasha L. Lin⁴, Tiffany Tran, PhD^1,5*, Lyna E.S. Kabbani^2*, Alexander J. Ritter^2*, Linsey Stiles^3,5*, Johanna Ten Hoeve^6,7,8*, Jeremy R. Sanford^2,9*, Ajit S. Divakaruni^3* and Dinesh S. Rao, MD, PhD^1,10,11

¹Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA
²Department of Molecular, Cellular and Developmental Biology and Center for Molecular Biology of RNA, University of California, Santa Cruz, Santa Cruz, CA
³Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA
⁴Department of Medicine, Division of Hematology/Oncology, University of California, Los Angeles, Los Angeles, CA
⁵Department of Medicine, University of California, Los Angeles, Los Angeles, CA
⁶California Nanosystems Institute, University of California, Los Angeles, Los Angeles, CA
⁷UCLA Metabolomics Center, University of California, Los Angeles, Los Angeles, CA
⁸Crump Institute for Molecular Imaging,, University of California, Los Angeles, Los Angeles, CA
⁹Center for Biomolecular Science & Engineering, University of California, Santa Cruz, Santa Cruz, CA
¹⁰Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA
¹¹Broad Stem Cell Research Center, University of California, Los Angeles, Los Angeles, CA

Saurabh Zanwar, MD, MBBS¹, Joseph Novak^2*, Michael D Howe^3*, Moritz Binder, MD¹, Wilson I. Gonsalves, MD¹, Esteban Braggio, PhD⁴, Vincent Rajkumar, MD^1*, Dragan Jevremovic, M.D., Ph.D^5*, Surendra Dasari, PhD^6* and Shaji Kumar, MD¹

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Mayo Clinic, Hematology Data Science, Rochester, MN
³Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN
⁴Division of Hematology and Oncology, Mayo Clinic, Scottsdale, AZ
⁵Mayo Clinic, Rochester, MN
⁶Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN

Oscar Atkins^1*, Lingling Zhang^1*, Miu Shing Hung^1*, Christian Reinhardt^2* and Dinis Calado, PhD^3*

¹The Francis Crick Institute, Immunity and Cancer Laboratory, London, United Kingdom
²Essen University Hospital, Essen, Germany
³The Francis Crick Institute, London, United Kingdom

Sarah Spoeck^*, Nadine Kinz^* and Verena Labi, PhD^*

Innsbruck Medical University, Innsbruck, Tirol, Austria

Jithma P Abeykoon, MD¹, Shuhei Asada, MD, PhD², Guangli Zu, M.D.^2*, Yuna Hirohashi^3*, Divya Iyer, Ph.D^3*, Kalindi Parmar, PhD^4*, Lige Jiang^3*, Sirisha Mukkavalli, Ph.D^3*, Dongni Yi, MD^3*, Michelle Manske, MS, BS^5*, Xiaosheng Wu, MD^1*, Kimberly Gwin^5*, Thomas E. Witzig, MD⁶, Geoffrey I Shapiro, MD^3* and Alan D. D'Andrea, MD^2*

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Dana-Farber Cancer Institute, Boston, MA
³Dana-Farber Cancer Institute, Boston
⁴Dana-Farber Cancer Inst. Harvard Med. School, Boston, Boston, MA
⁵Mayo Clinic, Rochester, MN
⁶Division of Hematology, Mayo Clinic, Stabile 628, Rochester, MN

Yinghui Zhu^1*, Bowen Wu^2*, Tianyi Chen^1*, Miaomiao Liu^1*, Shangyu Hou^1*, Xuemei Wang^1*, Yiyi Yao^3*, Tao Zeng^4*, Jinyan Huang^5*, Jie Jin, M.D.² and Huafeng Wang^2*

¹State Key Laboratory of Cardiology and Medical Innovation Center, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, Shanghai, China
²Department of Hematology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Hangzhou, China
³Department of Hematology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⁴Biomedical big data center, the First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou, Hangzhou, China
⁵Biomedical big data center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China