Shelly Saini, MD¹, Andrew Y. Koh, MD^2* and Ayesha Zia, MD, MSc²

¹Dept. of Pediatrics, UT Southwestern Medical Center, Dallas, TX
²Dept. of Pediatrics; Division of Hematology-Oncology, UT Southwestern Medical Center, Dallas, TX

Waleed Ghanima, MD, PhD¹, Howard A. Liebman, MD, MA², Yu Hu^3*, Yoshitaka Miyakawa, MD^4*, Nichola Cooper, MD^5*, Güray Saydam, MD^6*, Marie Luise Hütter-Krönke, MD^7*, Sylvain Audia^8*, Mengjie Yao^9*, Ahmed Daak, MD, PhD, MSc, DPM/MFPM¹⁰, Imene Gouia, PharmD, MSc Health Economics^11*, Matias Cordoba, MD^12* and David J Kuter, MD, DPhil¹³

¹Østfold Hospital Trust, Grålum, Norway and Institute of Clinical Medicine, University of Oslo, Oslo, Norway
²University of Southern California, Los Angeles, CA
³Wuhan Xie'he Hospital, Wuhan, China
⁴Department of Hematology, Saitama Medical University, Saitama, Japan
⁵Hammersmith Hospital, London, United Kingdom
⁶Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Ege University, Izmir, Turkey
⁷Department of Hematology, Oncology and Tumorimmunology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany
⁸CHU Dijon Bourgogne - Hopital Francois Mitterrand, Dijon, France
⁹Sanofi, Bridgewater, NJ
¹⁰Sanofi, Cambridge, MA
¹¹HEVA, Sanofi, Chilly-Mazarin, France
¹²Global Medical, Sanofi, Cambridge, MA
¹³Hematology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA

Yu Yang, M.Med^1,2,3*, Huiyuan Li^1,2,4*, Xiaofan Liu, MD^1,3,5*, Hong Wang, MD^3*, Lei Zhang^1,4,5 and Renchi Yang, MD^1,2,3

¹School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
²Tianjin Institutes of Health Science, Tianjin, China
³State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences&Peking Union Medical College, Tianjin, China
⁴State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Tianjin Key Laboratory of Gene Therapy for Blood Diseases, CAMS Key Laboratory of Gene Therapy for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
⁵Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Vivianne S. Nelson^1,2,3*, Sufia N. Amini, MD, PhD^3*, Tanja Netelenbos, MD, PhD³, Marina Kartachova, MD, PhD^4*, Roger EG Schutgens, MD, PhD, MSc^5*, Otto Visser, MD PhD^6*, Peter E. Westerweel⁷, Jaap Jan Zwaginga, MD, PhD², Suzanne Hofstede-Van Egmond^8*, Rick Kapur, MD, PhD¹, Masja De Haas^2,9*, Leendert Porcelijn, MD^8* and Martin R. Schipperus, MD, PhD^10*

¹Department of Experimental Immunohematology, Sanquin Research, Amsterdam, Netherlands
²Department of Hematology, Leiden University Medical Center, Leiden, Netherlands
³Department of Hematology, HagaZiekenhuis, Den Haag, Netherlands
⁴Department of Nuclear Medicine, HagaZiekenhuis, The Hague, Netherlands
⁵Center for Benign Hematology, Thrombosis and Hemostasis - Van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands
⁶Department of Hematology, Isala Hospital, Zwolle, Netherlands
⁷Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, Netherlands
⁸Department of Immunohematology Diagnostics, Sanquin Diagnostic Services, Amsterdam, Netherlands
⁹Department of Immunohematology Diagnostics, Sanquin Research Institute, Amsterdam, the Netherlands, Amsterdam, Netherlands
¹⁰Department of Clinical Affairs, Sanquin Blood Bank, Amsterdam, Netherlands

Tomas Jose Gonzalez-Lopez, MD¹, Nuria Bermejo-Vega^2*, Rocío Cardesa-Cabrera^3*, Natalia Acedo Dominguez^4*, Josefa Luis-Navarro^5*, Sunil Lakhwani^6*, Silvia Bernat^7*, Guillermo Enrique Haces-Tirado^8*, Pilar Galán^9*, Maria Luisa Lozano^10*, Daniel Martinez Carballeira^11*, Roberto Hernandez^12*, Reyes Jimenez Barcenas^13*, Begoña Navas-Elorza^14*, Shally Marcellini^15*, Ana Torres-Tienza^16*, Alvaro Perona Blazquez^17*, Carmen Benet^18*, Dolores Fernandez-Jimenez^19*, Carolina López-Santamaría Castro^20*, Isidro Jarque^21*, Violeta Martínez Robles^22*, Isabel González-Gascón-y-Marín^23* and Gloria García-Donas Gabaldón^24*

¹Department of Hematology, Hospital Universitario de Burgos, Burgos, Spain
²Department of Hematology, Complejo Hospitalario Universitario de Cáceres, Caceres, ESP
³Hospital Público Comarcal de La Merced, Osuna, Seville, ESP
⁴Hospital Universitario de La Princesa, Madrid, ESP
⁵Hospital General de Riotinto, Minas de Riotinto, Huelva, Spain
⁶Hospital Universitario de Canarias, La Laguna, Spain
⁷Hospital Universitario de La Plana, Villareal, Castellón, Spain, Villareal, Spain
⁸Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain
⁹Complejo Asistencial de Segovia, Segovia, ESP
¹⁰Hospital Morales Meseguer, Murcia, ESP
¹¹Hospital Universitario Central de Asturias, Oviedo (Asturias), Spain
¹²Complejo Asistencial de Zamora, Zamora, Spain
¹³Hospital de la Serranía de Ronda, Ronda, Málaga., Ronda (Málaga), Spain
¹⁴Hospital Clínico San Carlos, Madrid, ESP
¹⁵Complejo Asistencial de Segovia, Segovia, Spain
¹⁶Hospital General de Segovia, Segovia, Spain, Segovia, Spain
¹⁷Complejo Hospitalario Universitario de Albacete, Albacete, Spain
¹⁸Hospital Arnau de Vilanova, Valencia, Spain
¹⁹Hospital Universitario San Cecilio, Granada, Spain, Granada, Spain
²⁰Hospital Universitario de Badajoz, Badajoz, Spain
²¹Hematology Department, Hospital Universitari i Politècnic La Fe, Centro de Investigación Biomédica en Red de Cáncer – CIBERONC, Valencia, Spain
²²Complejo Asistencial Universitario de León, León, Spain
²³Hospital Universitario Infanta Leonor, Madrid, Spain
²⁴Hospital Universitario Virgen Macarena, Sevilla, Spain

Lamya Garabet, MD, PhD^1,2*, Waleed Ghanima, MD, PhD¹, Åse-Berit Mathisen^1*, Stine Jeanette Lae^1*, Marie Skogstad Le^3*, James B. Bussel, MD⁴, Andreas Hillarp, MD, PhD^3* and Carola Henriksson, MD, PhD^3*

¹Ostfold Hospital Trust, Grålum, Norway
²Akershus University Hospital, Lørenskog, Norway
³Oslo University Hospital, Oslo, Norway
⁴Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY

Shaan D. Shah^1*, Dinesh A. Rathod, MD^2,3*, Nita D. Rathod, MD^4*, Gaurang B. Modi, MD, DM^5* and Aarti H. Vibhakar, MD^3,6*

¹B.J. Medical College, Ahmedabad, India
²Green Cross Genetics Lab Pvt. Ltd., Gandhinagar, India
³Hematology Clinic, 402, Narayan Complex, Ahmedabad, India
⁴Department of Physiology, Narendra Modi Medical College, Ahmedabad, India
⁵Oncowin Cancer Center, Ahmedabad, India
⁶Purelab, Al Qassimi Hospital, Sharjah, United Arab Emirates

Yu Hu^1*, Renchi Yang, MD², Xiaofan Liu, MD^2*, Heng Mei, md, phd^3*, Hu Zhou⁴, Shujie Wang^5*, Ruibin Huang, MD^6*, Yi Wang^7*, Xin Du^8*, Jing Sun^9*, Zeping Zhou^10*, Zhenyu Yan^11*, Wenming Chen^12*, Wei Wang^13*, Qingchi Liu^14*, Qingshu Zeng^15*, Yuping Gong^16*, Jie Yin^17*, Xuliang Shen^18*, Baodong Ye^19*, Yun Chen^20*, Yajing Xu, MD^21*, Huiping Sun^22*, Yunfeng Cheng²³, Zhuogang Liu^24*, Chunling Wang, PhD^25*, Guolin Yuan^26*, Xiaohui Zhang²⁷, Xin Li^28*, Peng Cheng^29*, Xinhong Guo^30*, Zhongxing Jiang^31*, Feng'e Yang^32*, Linhua Yang^33*, Chengwei Luo Luo, M.D.^34*, Taiwu Xiao^35*, Hongyan Yin^36*, Xiaojun Guo^36*, Xian Luo^36*, Songhua Fan^36*, Michael M. Shi^36* and Weiguo Su^36*

¹Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
²Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
³Union Hospital, Tongji Medical College, HUST, Wuhan, China
⁴Department of Hematology, Henan Provincial Cancer Hospital, Zhengzhou, China
⁵Peking Union Medical College Hospital, Beijing, China
⁶The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China
⁷Shaanxi Provincial People's Hospital, Xi'an, China
⁸Department of Hematology and Shenzhen Bone Marrow Transplantation Public Service Platform, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China
⁹Nanfang Hospital Southern Medical University, Guangzhou, China
¹⁰Second Affiliated Hospital of Kunming Medical University, Kunming, China
¹¹North China University of Science and Technology Affiliated Hospital, Tangshan, China
¹²Beijing Chaoyang Hospital Affiliated to Capital Medical University, Beijing, China
¹³The Affiliated Hospital of Qingdao University, Qingdao, China
¹⁴The First Hospital of Hebei Medical University, Shijiazhuang, China
¹⁵Department of Hematology, The First Affiliated Hospital of Anhui Medical University, Hefei, China
¹⁶West China Hospital of Sichuan University, Chengdu, China
¹⁷First Affiliated Hospital of Soochow University, Suzhou, China
¹⁸Heping Hospital Affiliated To Changzhi Medical College, Changzhi, China
¹⁹The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China
²⁰Central Hospital Affiliated to Shandong First Medical University, Jinan, China
²¹Xiangya Hospital, Central South University, Changsha, Hunan, China
²²Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
²³Jinshan Hospital of Fudan University, Shanghai, China
²⁴Shengjing Hospital of China Medical University, Shenyang, China
²⁵Department of Hematology, The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, Huai'an, China
²⁶Xiangyang Central Hospital, Xiangyang, China
²⁷Peking University People's Hospital, Beijing, China
²⁸Department of Hematology, Third Xiangya Hospital of Central South University, Changsha, China
²⁹The First Affiliated Hospital of Guangxi Medical University, Nanning, China
³⁰The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China
³¹The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
³²Fujian Medical University Union Hospital, Fuzhou, China
³³The Second Hospital of Shanxi Medical University, Taiyuan, China
³⁴Department of Hematology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China
³⁵Liaocheng People's hospital, Liaocheng, CHN
³⁶HUTCHMED Limited, Shanghai, China

Michael D Tarantino, MD¹, Scott Kolodny, MD^2*, Michael Marrone, PhD^2*, Brian Jamieson² and Michael Vredenburg, PhD^2*

¹Bleeding and Clotting Disorders Institute, Peoria, IL
²Sobi Inc., Waltham, MA

Michael D Tarantino, MD¹, Scott Kolodny, MD^2*, Jessica Zhang, MS^2*, Brian Jamieson² and Michael Vredenburg, PhD^2*

¹Bleeding and Clotting Disorders Institute, Peoria, IL
²Sobi Inc., Waltham, MA

Jun Li^1*, Xiaoli Li^2* and Xiaofan Zhu, MD³

¹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences&Peking Union Medical College, Tianjin, China
²Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, tianjin, China
³Tianjin Institutes of Health Science, Tianjin, China

Julia Manasson, MD^*, Liliana Sanmarco, PhD^*, Alex Pellerin, PhD^*, Jordan Anderson, PhD^*, Nathan Rollins, PhD^*, Tobias Green, BS^*, Agustin Plasencia, BS^*, Andita Newton, MS^*, Ryan Peckner, PhD^*, Yi Xing, PhD^*, Heather Vital, MS, MBA^*, Nathan Higginson-Scott, PhD^*, John S Sundy, MD, PhD^*, Kevin L Otipoby, PhD^* and Ivan Mascanfroni, PhD^*

Seismic Therapeutic, Watertown, MA

Kannan Meganathan, PhD^1*, Samarjit Maharana, PhD^1*, Chitrali Laha Roy, M.Sc^1*, Fakiha Siddiqui, BDS^2*, Ravi Ranjan, PhD^3*, Jawed Fareed, PhD⁴, Manoranjan Mahapatra, MD^3* and Renu Saxena, MD^3*

¹Department of Biotechnology (Formerly known as Department of Life Sciences), Central University of Tamil Nadu, Thiruvarur, Tamilnadu, India
²Department of Molecular Pharmacology and Neuroscience, Loyola University Medical Center, Maywood, IL
³Department of Hematology, All India Institute of Medical Sciences, New Delhi, India
⁴Department of Molecular Pharmacology and Neuroscience, Department of Pathology and Laboratory Medicine, Cardiovascular Research Institute, Health Science Division, Loyola University Chicago, Maywood, IL

Dawid Mehlich, MD, PhD^1*, Ayobami Olafimihan, MBBS¹, Alejandro Vallejo, DO^1* and Shelby D. Rifkin, MD²

¹Medicine, John H. Stroger Jr. Hospital of Cook County, Chicago, IL
²Hematology & Oncology, John H. Stroger Jr. Hospital of Cook County, Chicago

Donald Arnold, MD¹, Yang Liu, MMath^1*, Na Li, PhD^2*, Madison Cranstone^1*, Syed Mahamad, MSc^1* and Ishac Nazy, PhD³

¹Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada
²Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada
³Michael G. DeGroote School of Medicine, Department of Medicine, McMaster University, Hamilton, ON, Canada

Kexin Shen^*, Chen Zhao^*, Lulu Wang^*, Mengtong Zang^*, Peng Zhao^*, Zhuo-Yu An^*, Xiaolu Zhu^*, Qiusha Huang, MD^*, HaiXia Fu, MD^*, Xiaojun Huang and Xiaohui Zhang, MD

Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China

Candelaria O'Farrell, MD¹, Taylor M. Luckie, MD¹, Susan E. Kirk, PA-C^2*, Jennifer Geris^3*, Michael E. Scheurer, PhD⁴ and Amanda B. Grimes, MD^5,6

¹Texas Children's Hospital / Baylor College of Medicine, Houston, TX
²Cancer and Hematology Center, Texas Children's Hospital, Houston, TX
³University of Minnesota, Minneapolis, MN
⁴Department of Pediatrics, Baylor College of Medicine, Houston, TX
⁵Texas Children’s Cancer and Hematology Center, Houston, TX
⁶Baylor College of Medicine, Houston, TX

Karan Srisurapanont, MD^1*, Ekdanai Uawithya, MD^2*, Pojsakorn Danpanichkul, MD^3*, Rinrada Worapongpaiboon, MD^4* and Chatree Chai-Adisaksopha, M.D., Ph.D.^1,5*

¹Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
²Division of Neurology, Department of Internal Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
³Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX
⁴Department of Medicine, Ratchaburi Hospital, Bangkok, Thailand
⁵Maharaj Nakorn Chiang Mai Hospital, Chiang Mai, Thailand

Elena Monzón Manzano, PhD^1*, María Teresa Alvarez-Román, PhD, MD^1,2*, Lucía del Pino, PhD^3*, Paula Acuña^1*, Rick Kapur, MD, PhD⁴, Leendert Porcelijn, MD^5*, Monica Martin Salces, PhD, MD^1*, Elena G Arias-Salgado, PhD^1*, Maria Isabel Rivas Pollmar, PhD, MD^1*, Ana Mendoza^1*, Eduardo López Granados^3*, Victor Jimenez Yuste, MD, PhD^1,2* and Nora Butta, PhD^1*

¹Hospital Universitario La Paz-IdiPAZ, Madrid, Spain
²Faculty of Medicine, Universidad Autonoma de Madrid, Madrid, Spain
³Servicio de Inmunología Clínica, Hospital Universitario La Paz- Grupo de Fisiopatología Linfocitaria en Inmunodeficiencias IdiPAZ y Centro de Investigación Biomédica en Red de Enfermedades Raras(CIBERER U767), Madrid, Spain
⁴Sanquin Research and Landsteiner Laboratory, Amsterdam, Netherlands
⁵Department of Immunohematology Diagnostics, Sanquin Diagnostic Services, Amsterdam, Netherlands

Jing Zhang^1*, Jia Chen, MD^1*, Renchi Yang, MD^2* and Lei Zhang³

¹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Tianjin, China
²State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Tianjin Key Laboratory of Gene Therapy for Blood Diseases, CAMS Key Laboratory of Gene Therapy for Blood Diseases, C, TIianjin, China
³State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Tianjin Key Laboratory of Gene Therapy for Blood Diseases, CAMS Key Laboratory of Gene Therapy for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Hanny Al-Samkari, MD¹, Vickie McDonald, MD, PhD, FRPATH, MRCP^2*, Monica Carpenedo, MD^3*, Francesco Zaja, MD^4*, Nichola Cooper, MD^5*, Spero Cataland, MD⁶, Michael W Drazer, MD, PhD⁷, Yoshitaka Miyakawa, MD^8*, Marc Michel, MD^9*, Jaume Ayguasanosa, MD^10*, Janki Brahmbhatt, MD^10*, Lan Lan, PhD^10*, Filip Matthijssens, PhD^10*, Catherine M. Broome, MD¹¹ and Waleed Ghanima, MD^12*

¹Division of Hematology Oncology, Massachusetts General Hospital, Boston, MA
²Barts Health NHS Trust, The Royal London Hospital, London, United Kingdom
³Ospedale L. Sacco, ASST Fatebenefratelli-Sacco, Milan, Italy
⁴DSM, University of Trieste and Department of Hematology, Azienda Sanitaria Universitaria Giuliano-Isontina, Trieste, Italy
⁵Imperial College Healthcare NHS Trust, London, United Kingdom
⁶Division of Hematology, The Ohio State University, Columbus, OH
⁷Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL
⁸Department of Hematology, Saitama Medical University Hospital, Saitama, Japan
⁹Department of Internal Medicine, Henri Mondor University Hospital, Assistance Publique-Hôpitaux de Paris, Paris-Est Créteil University, Créteil, France
¹⁰argenx, Ghent, Belgium
¹¹Division of Hematology, MedStar Georgetown University Hospital, Washington, DC, USA, Washington
¹²Østfold Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway