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Engaging Elusive Tumor Cells with Immune Effectors

Symposia: Scientific Workshop on Understanding and Overcoming Tumor-intrinsic Resistance to CAR-T Therapies for Lymphoid Malignancies Program: Scientific Workshops
Friday, December 6, 2024: 2:05 PM-2:41 PM
Room 28 A-D (San Diego Convention Center)
Moderator:
and Francesco Maura, MD, University of Miami
Disclosures:
Maura: Medidata: Consultancy, Honoraria; Sanofi: Consultancy, Honoraria.

Interactions between lymphoma cells and their microenvironments underlie the biology of these tumors and have substantial impact on CAR-T outcomes in patients. Here we review current understandings of these interactions in relation to CAR-T efficacy, emerging techniques to study them at high resolution, and how results can inform the design of next-generation CAR products with potential to benefit  increased numbers of patients.
Moderator Introduction

Francesco Maura, MD

University of Miami, Coral Gables, FL
Response and Resistance: A Tale of Tumor and T Cells

Frederick Locke, MD

Moffitt Cancer Center, Tampa, FL
Integrative Genomic Analysis Identifies Unique Immune Environments Associated with Immunotherapy Response in Diffuse Large B-Cell Lymphoma

Justin Kline, MD

University of Chicago, Chicago, IL
How Resistance Mechanisms Can Inform the Design of Next-Generation Cars Aimed at Improved Efficacy

Jay Y Spiegel, MD, FRCPC

University of Miami, Miami, FL
Panel Discussion
See more of: Scientific Workshop on Understanding and Overcoming Tumor-intrinsic Resistance to CAR-T Therapies for Lymphoid Malignancies
See more of: Scientific Workshops
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