Jan-Niklas Eckardt^1,2*, Waldemar Hahn, MSc^3,4*, Rhonda E. Ries, MA^5*, Szymon Dariusz Chrost, MSc^6*, Susann Winter, PhD^2*, Sebastian Stasik, PhD^6*, Christoph Röllig, MD, MSc^7*, Uwe Platzbecker, MD⁸, Carsten Müller-Tidow, MD^9*, Hubert Serve, MD¹⁰, Claudia D Baldus, MD^11*, Christoph Schliemann, MD^12*, Kerstin Schäfer-Eckart, MD^13*, Maher Hanoun, MD, PhD^14*, Martin Kaufmann, MD¹⁵, Andreas Burchert, MD¹⁶, Johannes Schetelig, MD, MSc¹⁷, Martin Bornhäuser, MD^6,18,19*, Markus Wolfien, PhD^3,4*, Soheil Meshinchi, MD, PhD⁵, Christian Thiede, MD⁶ and Jan Moritz Middeke, MD^6,20*

¹Else Kroener Fresenius Center for Digital Health, TUD Dresden University of Technology, Dresden, Germany
²Department of Internal Medicine I, University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany
³Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI) Dresden/Leipzig, Dresden, Germany
⁴Institute for Medical Informatics and Biometry, TUD Dresden University of Technology, Dresden, Germany
⁵Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle, WA
⁶Department of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany
⁷Department of Internal Medicine I, University Hospital Carl Gustav Carus, Dresden, Germany
⁸Department for Hematology, Cell Therapy, Hemostaseology and Infectious Diseases, University of Leipzig Medical Center, Leipzig, Germany
⁹Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany
¹⁰Department of Medicine II, Hematology/Oncology, Goethe University, University Hospital, Frankfurt, Germany
¹¹University Medical Center Schleswig-Holstein, University Cancer Center Schleswig-Holstein, Kiel, Germany
¹²Department of Medicine A, University Hospital Muenster, Muenster, Germany
¹³Department of Internal Medicine V, Paracelsus University Hospital Nuremberg, Nuremberg, Germany
¹⁴Department of Hematology and Stem Cell Transplantation, University Hospital Essen, Essen, Germany
¹⁵Department of Hematology, Oncology and Palliative Care, Robert Bosch Hospital, Stuttgart, Germany
¹⁶Department of Hematology, Oncology and Immunology, University Hospital Marburg, Marburg, Germany
¹⁷Department of Internal Medicine I, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
¹⁸German Cancer Consortium (DKTK), Partner Site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany
¹⁹National Center for Tumor Diseases Dresden (NCT/UCC), Technical University Dresden, Dresden, Germany
²⁰Else Kroener Fresenius Center for Digital Health, Technical University Dresden, Dresden, Germany

Jessica Nordlund, MSc, PhD^1,2*, Maria Globisch, PhD^1*, Henrik Gezelius, PhD^1*, Anna Pia Enblad, MD^1*, Olga Krali, MSc^1*, Mariya Lysenkova-Wiklander, BSc^1*, Martin Åberg, MSc^3*, Arja Harila, MD, PhD^4*, Amanda Raine, PhD^1* and Claes Andersson, PhD^1*

¹Medical Sciences, Uppsala University, Uppsala, Sweden
²Science for Life Laboratory, Uppsala, Sweden
³Department of Clinical Chemistry and Pharmacology, Uppsala University Hospital, Uppsala, Sweden
⁴Women's and Children's Health, Uppsala University, Uppsala, Sweden

Bofei Wang, PhD¹, Poonam N Desai², Jae Jun Ku^3*, Naval Daver, MD⁴, Patrick K. Reville, MD, MPH² and Hussein A. Abbas, MD, PhD²

¹Department of Leukemia, Division of Cancer Medicine, The University of Texas At MD Anderson Cancer Cent, Houston, TX
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³Rice University, Houston, TX
⁴MD Anderson Cancer Center, Houston, TX

Shazia K. Nakhoda, MD^1*, Pin Lu, PhD^1*, Tingwei Guo, PhD^1*, Denise Connelly, PhD^1*, Marcus Messmer, MD¹, Zachary AK Frosch, MD, MSHP², Henry C. Fung, FRCP, MBBChir³, Asya Varshavsky Yanovsky, MD, PhD¹ and Y. Lynn Wang, MD, PhD¹

¹Fox Chase Cancer Center, Philadelphia, PA
²Department of Hematology/Oncology; Cancer Prevention and Control Research Program, Fox Chase Cancer Center, Philadelphia, PA
³Fox Chase Cancer Center, Temple University Health System, Philadelphia, PA

Xiangjie Lin^1*, Huafeng Wang^2,3,4,5,6* and Jie Jin, M.D.^3,7,8,9,10

¹Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
²Zhejiang Provincial Clinical Research Center for Hematological disorders, Hangzhou, China
³Zhejiang University Cancer Center, Hangzhou, China
⁴Zhejiang Provincial Clinical Research Center for Hematological disorders, Hangzhou, Zhejiang, Hangzhou, China
⁵Department of Hematology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⁶Zhejiang Provincial Key Lab of Hematopoietic Malignancy, Zhejiang University, Hangzhou, Zhejiang, Hangzhou, China
⁷Department of Hematology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
⁸Zhejiang Provincial Clinical Research Center For Hematological disorders, Hangzhou, China
⁹Zhejiang Provincial Key Lab of Hematopoietic Malignancy, Zhejiang University, Hangzhou, Zhejiang, PR China;, Hangzhou, China
¹⁰Zhejiang Provincial Key Laboratory of Hematopoietic Malignancy, Zhejiang University, Hangzhou, China

Akshay A Patwardhan^1*, Ashwin P. Patel, MD, PhD, MPH², Solomon Oshabaheebwa, MSc, BSc^3*, Christopher A. Delianides, MS^4*, Zoe Sekyonda, BS^4*, Erica N Evans^1*, Abhinav K Pasupuleti^5*, Lindsey Abel, BS^2*, Michael A. Suster, PhD^4*, Pedram Mohseni, PhD^4*, Umut Gurkan, PhD⁴ and Vivien Sheehan, MD, PhD^1,6

¹Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA
²Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA
³Case Western Reserve University, Cleveland Heights, OH
⁴Case Western Reserve University, Cleveland, OH
⁵Aflac Blood and Cancer Center, Children’s Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, Atlanta, GA
⁶Emory University School of Medicine, Atlanta, GA

Ramy El-Assal^1* and Aziz Nazha, MD²

¹The Ohio State University, Columbus
²Thomas Jefferson University, Department of Medical Oncology, Philadelphia, PA

Yoonkyu Lee, MS, BS^1,2,3, Wen Wang, PhD^4*, Timothy K Starr, PhD^1,5*, Klara E Noble-Orcutt, BS, MS^1,3*, Chad L Myers, PhD^1,2,4* and Zohar Sachs, MD, PhD^1,2,3

¹Masonic Cancer Center, University of Minnesota, Minneapolis, MN
²Bioinformatics and Computational Biology Program, University of Minnesota, Minneapolis, MN
³Division of Hematology, Oncology, and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN
⁴Department of Computer Science and Engineering, University of Minnesota, Minneapolis, MN
⁵Department of Obstetrics, Gynecology, and Women's Health, University of Minnesota, Minneapolis, MN

Lindsey A. Murphy, MD¹, Laura Sedivy^2*, M. Eric Kohler, MD, Ph.D³, Kimberly Jordan, PhD^2*, Jill Slansky^2*, Michael Yarnell, BSc^2*, Terry J Fry, MD⁴ and Amanda Winters, MD, PhD²

¹City of Hope, Duarte, CA
²University of Colorado Anschutz Medical Campus, Aurora, CO
³Division of Hematology/Oncology/Bone Marrow Transplant and Center for Cancer and Blood Disorders, Ch, Aurora, CO
⁴Immunology Department and HI3 Initiative, University of Colorado Anschutz Medical Campus, Aurora, CO

Melanie E. Fields, MD¹, Paula Germino-Watnick^2*, Amy Mirro, BSc^3*, Jinli Wang^2*, Landon C. Power^3*, Josiah Lewis, PHD^4*, Kristin P. Guilliams, MD, MSCI^5*, Yasheng Chen^4* and Andria L. Ford, MD, MSCI^6*

¹Division of Pediatric Hematology and Oncology, Washington University, St. Louis, MO
²Washington University of St Louis, St. Louis, MO
³Washington University, St. Louis, MO
⁴Washington University School of Medicine in St Louis, St. Louis, MO
⁵Division of Pediatric Neurology, Washington University, St. Louis, MO
⁶Washington University School of Medicine in St Louis, St. Louis

Saverio D'Amico, MSc^1,2*, Elisabetta Sauta, PhD^2*, Gianluca Asti, MSc^2*, Mattia Delleani^2*, Elena Zazzetti, MSc^2*, Alessia Campagna, MD^2*, Luca Lanino, MD³, Giulia Maggioni, MD^2*, Marta Ubezio, MD^2*, Gabriele Todisco, MD^4*, Antonio Russo, MD^2*, Cristina Astrid Tentori, MD^2*, Alessandro Buizza, MD^2*, Matteo Franchi, PhD^5*, Lorenzo Dall'Olio, PhD^6*, Marilena Bicchieri, PhD^2*, Matteo Zampini, PhD^3*, Matteo Brindisi^3*, Francesca Ficara, PhD^2*, Elena Riva, PhD^3*, Denise Ventura, MSc^3*, Laura Crisafulli, PhD^3*, Nicole Pinocchio, MSc^3*, Andrea Della Porta^1*, Flavia Jacobs, MD^2*, Alberto Zambelli, MD^2*, Victor Savevski, MEng^2*, Armando Santoro, MD^7*, Francesc Sole, PhD⁸, Uwe Platzbecker, MD⁹, Pierre Fenaux, MD¹⁰, Maria Diez-Campelo, MD, PhD^11*, Guillermo Garcia-Manero, MD¹², Torsten Haferlach, MD¹³, Shahram Kordasti, MD, PhD^14,15, Gastone Castellani, PhD^16*, Fabio Efficace, PhD^17*, Valeria Santini, MD¹⁸, Amer M. Zeidan, MD¹⁹, Rami S. Komrokji, MD²⁰ and Matteo Giovanni Della Porta, MD^2,21*

¹Train s.r.l., Milan, Italy
²IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy
³IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy
⁴IRCCS Humanitas Research Hospital, Houston, TX
⁵Unit of Biostatistics, Epidemiology and Public Health, Department of Statistics and Quantitative Methods, University of Milano-Bicocca, Milan, Italy
⁶Department of Physics and Astronomy, University of Bologna, Bologna, Italy
⁷IRCCS Humanitas Research Hospital, Rozzano, Italy
⁸Josep Carreras Leukaemia Research Institute, Myelodysplastic Syndromes Research Group, Badalona, Spain
⁹Department for Hematology, Cell Therapy, Hemostaseology and Infectious Diseases, University of Leipzig Medical Center, Leipzig, Germany
¹⁰Service d'Hématologie Séniors, Hôpital Saint-Louis, Université Paris 7, Paris, France
¹¹Hospital Clínico Universitario de Salamanca, Salamanca, Spain
¹²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
¹³MLL Munich Leukemia Laboratory, Munich, Germany
¹⁴Hematology Unit, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Ancona, Italy
¹⁵Kings College London, London, United Kingdom
¹⁶Dipartimento di Scienze Mediche e Chirurgiche, Università di Bologna, Bologna, Italy
¹⁷Gruppo Italiano Malattie Ematologiche Dell’Adulto GIMEMA, Rome, Rome, Italy
¹⁸MDS Unit, Hematology, AOUC, University of Florence, Florence, Italy
¹⁹Yale School of Medicine and Yale Comprehensive Cancer Center, Yale University, New Haven, CT
²⁰Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
²¹Department of Biomedical Sciences, Humanitas University, Milan, Italy

Shu Wang, PhD^*, Saurabh Parikh, PhD^*, Dongjo Ban^*, Saurabh Gulati^*, Qawer Ayaz^*, Joanne Nguyen^*, Benjamin Miltz^*, Yang Li^* and Ben Schroeder^*

Mission Bio, South San Francisco, CA

Takeshi Sugio, MD, PhD^1*, Mohammad Shahrokh Esfahani, PhD^2*, Soyeong Jun, PhD^2*, Brian J. Sworder, MD, PhD³, Mark P. Hamilton, MD, PhD⁴, Hitomi Hosoya, MD, PhD⁴, Mari Olsen, BS^1*, Xiaoman Kang, BS^5*, Chih Long Liu, PhD^1*, Feng Tian, PhD^1*, David B. Miklos, MD, PhD⁴, David Kurtz, MD, PhD⁶, Maximilian Diehn, MD, PhD^2* and Ash A. Alizadeh, MD, PhD¹

¹Department of Medicine, Divisions of Oncology and Hematology, Stanford University, Stanford, CA
²Department of Radiation Oncology, Stanford University, Stanford, CA
³Division of Hematology and Oncology, University of California, Irvine, Irvine, CA
⁴Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Palo Alto, CA
⁵Department of Medicine, Division of Oncology, Stanford University, Stanford, CA
⁶Department of Medicine (Oncology), Stanford University, Palo Alto, CA

Arda Durmaz, PhD^1*, Zachary Brady^2*, Kartik Lakhotiya, MS^2*, Benjamin Kroger, BS³, Hussein Awada², Yasuo Kubota, MD, PhD^2*, Jacky Chen^4*, Colin Hercus^5*, Sébastien Hergalant, PhD^6*, Carlos Bravo-Perez, MD^2,7*, Maria Teresa Voso, MD⁸, Li Lily Wang^2*, Jacob G. Scott, MD, DPhil^9*, Hetty E. Carraway, MD, MBA¹⁰, Valeria Visconte, PhD², Stephen Chung, MD¹¹, Simona Pagliuca, MD, PhD¹², Jaroslaw Maciejewski² and Carmelo Gurnari, MD, PhD^8,13

¹Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Foundation, CLEVELAND, OH
²Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
³Division of Hematology/Oncology, Department of Internal Medicine, University of Texas Southwestern, Dallas, TX
⁴Cleveland Clinic Lerner College of Medicine, Cleveland, OH
⁵Novocraft Technologies Sdn Bhd, Kuala Lumpur, Malaysia
⁶UMR Inserm 1256 NGERE (Nutrition, Génétique et Exposition aux Risques Environnementaux), Université de Lorraine, Faculté de médecine, Vandoeuvre-lès-Nancy, France
⁷Department of Hematology and Medical Oncology, Hospital Universitario Morales Meseguer, University of Murcia, IMIB-Pascual Parrilla, CIBERER - Instituto de Salud Carlos III, Murcia, Spain
⁸Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
⁹Systems Biology and Bioinformatics Department, School of Medicine, Case Western Reserve University, Cleveland, OH
¹⁰Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
¹¹Division of Hematology/Oncology, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX
¹²Department of Hematology, Nancy University Hospital, Vandœuvre-lès-Nancy, France, France
¹³Cleveland Clinic Foundation, Cleveland, OH

Mayu Ikeda^1*, Yuki Namba, MSc^1*, Rinko Sasaki, MSc^1*, Ryotaro Miyamoto, MSc^1*, Hikaru Hattori, PhD^1*, Michitaka Notoya, PhD^1*, Motonari Daito, MSc^1*, Yuichiro Semba, MD, PhD^2,3*, Koichi Akashi, MD, PhD^3* and Takahiro Maeda, MD, PhD²

¹Reagent Engineering, Sysmex Corporation, Kobe, Japan
²Division of Precision Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
³Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan

Adrian Mosquera Orgueira, MD, PhD^1*, Marta Sonia Gonzalez Perez^2*, Mattia D'Agostino, MD^3*, David A. Cairns, PhD^4*, Alessandra Larocca, MD⁵, Juan José Lahuerta Palacios, MD, PhD^6*, Ruth Wester, MD, PhD^7*, Uta Bertsch, MD^8,9*, Anders Waage, MD, PhD^10*, Elena Zamagni, MD^11,12*, Carlos Pérez Míguez^13*, Niels W.C.J. Van De Donk, MD¹⁴, Graham Jackson, MD^15*, Davide Crucitti^13*, Hans Salwender, MD^16*, Daniele Dall'Olio, PhD^17*, Gastone Castellani, PhD^18*, Manuel Piñeiro Fiel^13*, Sara Bringhen, MD, PhD¹⁹, Sonja Zweegman, MD, PhD²⁰, Michele Cavo, MD^21,22*, Jesus Maria Hernandez Rivas, MD²³, Benedetto Bruno, MD, PhD³, Gordon Cook, PhD, DSc^4*, Martin F Kaiser, MD²⁴, Hartmut Goldschmidt, MD^8,25, Pieter Sonneveld, MD⁷, Jesús F. San-Miguel, MD, PhD²⁶, Mario Boccadoro, MD²⁷ and Maria- Victoria Mateos²⁸

¹University Hospital of Santiago de Compostela, Department of Hematology, IDIS, SANTIAGO DE COMPOSTELA, Spain
²University Hospital of Santiago de Compostela, Santiago de Compostela, Spain
³Division of Hematology, AOU Città della Salute e della Scienza di Torino, University of Torino and Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy
⁴Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, United Kingdom
⁵Division of Hematology, Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy
⁶Hospital Universitario 12 de Octubre, CIBER-ONC CB16/12/00369, CNIO, Madrid, Spain
⁷Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands
⁸National Center for Tumor Diseases Heidelberg, Heidelberg, Germany
⁹Department of Medicine V, Heidelberg Myeloma Center, University Hospital Heidelberg, Heidelberg, Germany
¹⁰Institute of Clinical and Molecular Medicine, Norwegian University of Science and Technology, and Research Department, St Olavs Hospital, Trondheim, Norway
¹¹"Seràgnoli" Institute of Hematology, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
¹²Istituto di Ematologia “Seràgnoli”, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
¹³University Hospital of Santiago de Compostela, Department of Hematology, Santiago de Compostela, Spain, Santiago de Compostela, Spain
¹⁴Cancer Center Amsterdam, VU University Medical Center, Amsterdam, Netherlands
¹⁵University of Newcastle, Department of Haematology, Newcastle, United Kingdom
¹⁶Asklepios Tumorzentrum Hamburg, Asklepios Hospital Hamburg Altona and St. Georg, Hamburg, Germany, Hamburg, Germany
¹⁷University of Bologna, Bologna, Italy
¹⁸Dipartimento di Scienze Mediche e Chirurgiche, Università di Bologna, Bologna, Italy
¹⁹Citta' Della Salute E Della Scienza, Torino, To, Italy
²⁰Department of Hematology, Amsterdam UMC, Cancer Center Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
²¹IRCCS Azienda Ospedaliero-Universitaria di Bologna, Hematology Institute “L. e A. Seràgnoli”, Bologna, Italy
²²Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy
²³Department of Medicine, University of Salamanca, Institute of Biomedical Research of Salamanca (IBSAL), University of Salamanca – Cancer Research Center of Salamanca (IBMCC, USAL-CSIG), Salamanca, Spain
²⁴The Institute of Cancer Research, London, United Kingdom and the Royal Marsden Hospital, London, United Kingdom
²⁵Internal Medicine V, Hematology, Oncology and Rheumatology, GMMG Studygroup, Heidelberg University Hospital, Heidelberg, Germany
²⁶Clínica Universidad de Navarra, CIMA, IDISNA, CIBER-ONC (CB16/12/00369), Pamplona, Spain
²⁷European Myeloma Network, EMN, Italy
²⁸University Hospital of Salamanca/IBSAL/CIC/CIBERONC, Salamanca, Spain

Xuezi Hu^1*, Korsuk Sirinukunwattana^1*, Ka Ho Tam^1*, Alan Aberdeen^1*, Daniel Royston, DPhil, FRCPath, MBBChir² and Carlo Pescia^3*

¹Ground Truth Labs Ltd., Oxford, United Kingdom
²Nuffield Division of Clinical Laboratory Sciences, University of Oxford, Oxford, United Kingdom
³Università degli Studi di Milano, MILANO, Italy

Angelos-Michael Papadopoulos^1,2*, Anastasia Iatrou^3*, Apostolos Axenopoulos^1,4*, Paolo Ghia^5,6, Kostas Stamatopoulos^3*, Federico Alvarez, Prof, PhD^2* and Petros Daras^1*

¹Information Technologies Institute, Centre for Research and Technology Hellas, Thessaloniki, Greece
²Universidad Politécnica de Madrid, Madrid, Spain
³Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece
⁴Aristotle University of Thessaloniki, Thessaloniki, Greece
⁵Medical School, Università Vita-Salute San Raffaele, Milano, Italy
⁶Division of Experimental Oncology, IRCCS Ospedale San Raffaele, Milano, Italy

Sadegh Marzban^1*, Curtis Gravenmier, MD^2*, Ling Zhang, MD³, Lynn C. Moscinski, MD⁴ and Jeffrey West, PhD^5*

¹Integrated Mathematical Oncology Department, Moffitt Cancer Center & Research Institute, Tampa, FL
²Department of Hematopathology and Laboratory Medicine, Moffitt Cancer Center & Research Institute, Tampa
³Department of Pathology and Laboratory Medicine, H. Lee Moffitt Cancer and Research Institute, Tampa, FL
⁴Department of Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁵Integrated Mathematical Oncology Department, Moffitt Cancer Center & Research Institute, Tampa

David Bermejo-Peláez, PhD^1*, Ana Mendoza-Martinez^2*, Sandra Rodríguez San Antolín^3*, Miguel Gómez Álvarez^4*, Marta Hidalgo-Soto, MD^5*, Adriana Oñós Clausell^6*, Nuria Díez Navarro^7*, David Brau Queralt^7*, Maria Postigo Camps^7*, Lin Lin^8*, Roberto Mancebo-Martín^7*, Carla Caballero Moreno^7*, Alejandro Angulo Llorente^7*, Alexander Vladimirov^8*, Alba Rodríguez García^9*, Alejandra Ortiz-Ruiz^3*, Roberto Garcia-Vicente^10*, Raquel Ancos-Pintado^11*, Rafael Colmenares Gil^3*, Maria Jesus Ledesma-Carbayo^12*, María Linares^13*, Maria Julia Montoro, MD, PhD^14*, Celina Benavente Cuesta^15*, Miguel Luengo-Oroz^7* and Joaquín Martínez-Lopez^16*

¹Spotlab, Madrid, AL, Spain
²Department of Hematology, Hospital Universitario 12 de Octubre, Madrid, Spain
³Hospital Universitario 12 de Octubre, Madrid, Spain
⁴Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain
⁵Vall d’Hebron Institute of Oncology, Barcelona, Spain
⁶Hospital Universitari Vall d'Hebron, Barcelona, Spain
⁷Spotlab, Madrid, Spain
⁸Spotlab, Madrid, ESP
⁹Department of Translational Hematology, Research Institute Hospital 12 de Octubre (i+12), Hematological Malignancies Clinical Research Unit H120-CNIO, CIBERONC, Madrid, Spain, Madrid, ESP
¹⁰Department of Translational Hematology, Research Institute Hospital 12 de Octubre (i+12), Hematological Malignancies Clinical Research Unit H120-CNIO, CIBERONC, Madrid, Spain
¹¹Department of Translational Hematology, Research Institute Hospital 12 De Octubr, Madrid, ESP
¹²Universidad Politécnica de Madrid, Madrid, Spain
¹³Universidad Complutense de Madrid, Madrid, Spain
¹⁴Experimental Hematology. Hematology Department Vall d´Hebron Institute of Oncology (VHIO), Hospital Universitari Vall d’Hebrón, BARCELONA, Spain
¹⁵Department of Hematology and Hemotherapy, Hospital Clínico San Carlos, Madrid, Spain
¹⁶Hematology Department, Hospital Universitario 12 de Octubre, CIBER-ONC, Instituto de Investigación IMAS12, Madrid, Spain

Yuefan Huang, PhD^1*, Riya Dilip Thakkar, MS^1*, Katerina Kappes, BSc^2*, Kristan Steffen, PhD^1*, Oliver Venn, PhD^1*, Rita Shaknovich, MD, PhD¹, Qinwen Liu, PhD^1* and Samir Parekh, MD²

¹GRAIL, Inc., Menlo Park, CA
²Icahn School of Medicine at Mount Sinai, New York, NY

Surabhi Rao^1*, Victor Foster^2*, Charles Levine^2*, Bert Frederich, PhD^2*, Jonathan Chan^2*, Barry Campbell^2*, Glenda Arauz^2*, Celia Ortiz^2*, Adel Alonso^2*, Oliver Chen^2*, Tanaya Ghosh^2*, Charlotte He^2*, Elizabeth Del Greco^2*, David Satyadi^2*, Anagha Rao^2*, David Kim^2*, Dhruv Bole^2*, Katelyn N Benthall, PhD^2*, Margarita Krivega, PhD^2*, Julia Poniatowski^2*, Ivan Krivega, PhD³, Zoya Gulzman-Poltorak, PhD^2*, Steve Feinstein, MD^2* and Kenneth Greenberg, PhD^2*

¹Sonothera Inc, San Francisco, CA
²SonoThera, South San Francisco
³SonoThera, SOUTH SAN FRANCISCO, CA

Meihua Long^1,2*, Fan Jia^1,2*, Jili Deng^3*, Jianing Zhang^2*, Ziran Zhao, PhD^4,5, Yan Xie^2*, Lan Mi^2*, Yan Hou^1,2* and Yuqin Song, MD²

¹Department of Biostatistics, Peking University, Beijing, China
²Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Lymphoma, Peking University Cancer Hospital & Institute, Beijing, China
³Department of Oncology, Sichuan Cancer Hospital and Institute, Chengdu, China
⁴National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China
⁵First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China

Dan Yoon, MS^1*, Bita Jafarzadeh, MD^1*, Vahid Mehrtash, MD^1*, Hortense Le, MS^1,2*, Nicolas Coudray, PhD^3*, Aristotelis Tsirigos, PhD^1,2,3 and Christopher Y. Park, MD, PhD^1,2

¹Department of Pathology, New York University School of Medicine, New York, NY
²Department of Medicine, Division of Precision Medicine, New York University School of Medicine, New York, NY
³Applied Bioinformatics Laboratories, New York University School of Medicine, New York, NY

Johannes Schmoellerl^1*, Romana Maerschalk^1*, Martina Weissenboeck^1*, Jasmin Ali^1*, Thomas Köcher^2*, Aleksandra Bundalo^1*, Florian Andersch^1*, Vivien Vogt^1*, Bettina Sajtos^1*, Jonas Bayerl^1*, Martina Minnich^1*, Michaela Fellner^1* and Johannes Zuber, MD^1,3*

¹Research Institute of Molecular Pathology (IMP), Vienna, Austria
²Vienna BioCenter Core Facilities, Vienna, Austria
³Medical University of Vienna, Vienna, Austria

Shota Kato, MD^1*, Aiko Sato-Otsubo, MS^2*, Wataru Nakamura, MD^3*, Masahiro Sugawa, MD^3*, Ai Okada^3*, Kenichi Chiba, PhD^3*, Nao Takasugi^2*, Tomoya Irikura, MD^2*, Moe Hidaka, MD^2*, Masahiro Sekiguchi, MD, PhD^2*, Kentaro Watanabe, MD, PhD^2*, Yuichi Shiraishi, PhD^3* and Motohiro Kato, MD, PhD²

¹Department of Pediatrics, The University of Tokyo, Tokyo, Japan
²Department of Pediatrics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
³Division of Genome Analysis Platform Development, National Cancer Center Research Institute, Tokyo, Japan