Darren King^1*, Kai Wu^2*, Qianyi Ma^3*, Josephine Dubois^3*, Xianing Zheng^3*, Mohamed Rizk^3*, Kerby Shedden^3*, Malathi Kandarpa, PhD^4*, Dan Boyer^3*, Karan Bedi^3*, Jun Li^3* and Sami N. Malek, MD⁵

¹Rogel Cancer Center, University of Michigan, Ann Arbor, MI
²UCSF, San Francisco
³University of Michigan, Ann Arbor
⁴Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI
⁵Department of Medicine, University of Michigan Medical School, Ann Arbor, MI

Sofia Forstén^1,2,3*, Livius Penter, MD^4,5, Oscar E. Brück, MD, PhD^6*, Johannes Smolander, PhD^1,2,3*, Karita Peltonen, PhD^1,2,3*, Harri Lähdesmäki, PhD^7*, Mika Kontro, MD, PhD⁸, Kimmo Porkka, MD, PhD^1,2,3,8, Hussein A. Abbas, MD, PhD^9,10, Catherine J. Wu, MD^11,12,13*, Jani Huuhtanen, MD, PhD^1,2,3,7* and Satu Mustjoki, MD, PhD^1,2,3

¹Translational Immunology Research Program, University of Helsinki, Helsinki, Finland
²ICAN Digital Precision Cancer Medicine Flagship, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland
³Hematology Research Unit Helsinki, Department of Hematology, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland
⁴BIH Biomedical Innovation Academy Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany
⁵Department of Hematology, Oncology, and Tumorimmunology Charité - Universitätsmedizin Berlin, Berlin, Germany
⁶Hematoscope Lab, Comprehensive Cancer Center & Center of Diagnostics, Helsinki University Hospital & University of Helsinki, Helsinki, Finland
⁷Department of Computer Science, Aalto University, Espoo, Finland
⁸Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland
⁹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁰Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
¹¹Broad Institute of MIT and Harvard, Cambridge, MA
¹²Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
¹³Harvard Medical School, Boston, MA

Suravi Raychaudhuri, MD^1,2, Ted Gooley, PhD^2*, Megan Othus, PhD^2,3, Xiaoyu Qu, PhD^1*, Carole Shaw^1*, Kathryn Russell, ARNP^1,2*, Rutu D. Vyas, CRA^1*, Jacob S. Appelbaum, MD, PhD^2,4, Anna B. Halpern, MD^1,2, Roland B. Walter, MD, PhD, MS^5,6, Harry P. Erba, MD, PhD⁷, Min Fang, MD, PhD^1,2 and Mary-Elizabeth M. Percival, MD^4,8

¹Fred Hutchinson Cancer Center, Seattle, WA
²University of Washington, Seattle, WA
³Public Health Science Division, Fred Hutchinson Cancer Center, Seattle, WA
⁴Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA
⁵Department of Medicine, Division of Hematology and Oncology, University of Washington, Seattle, WA
⁶Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA
⁷Duke University Cancer Institute, Durham, NC
⁸Division of Hematology and Oncology, University of Washington School of Medicine, Seattle, WA

Mathilde Bastien, MS^1*, Maxime Jullien, MD^2*, Nicolas Vallet, MD^3*, Aline Schmidt, MD^4*, Tony Marchand, MD, PhD^5*, Amandine Le Bourgeois, MD^2*, Alice Garnier, MD^6*, Sophie Vantyghem, MD^2*, Aude-Marie Fourmont, MD^2*, Corentin Orvain^4*, Marc Bernard, MD^5*, Thierry Guillaume, MD, PhD^2*, Jean-Baptiste Méar, MD^5*, Mathilde Hunault, MD, PhD^4*, Emmanuel Gyan, MD, PhD^3*, Pierre Peterlin^2* and Patrice Chevallier, MD, PhD²

¹Hematology Clinic, Nantes University Hospital, NANTES, AE, France
²Hematology Clinic, Nantes University Hospital, Nantes, France
³Hematology Clinic, Tours University Hospital, Tours, France
⁴Hematology Clinic, Angers University Hospital, Angers, France
⁵Hematology Clinic, Rennes University Hospital, Rennes, France
⁶CHU Nantes Hôpital Hôtel Dieu Hématologie Clinique, Nantes, France

Ryo Yanagiya^1*, Yuriko Minegishi^2*, Makoto Onizuka³, Koji Ueda, PhD^2*, Ai Kotani^4* and So Nakagawa^5,6,7*

¹Research Institute for Microbial Diseases, Osaka University, Isehara, Japan
²Japanese Foundation for Cancer Research, Tokyo, Japan
³Department of Hematology/Oncology, Tokai University, Isehara, Japan
⁴Research Institute for Microbial Diseases, Osaka University, Suita, Japan
⁵Department of Molecular Life Science, Tokai University School of Medicine, Isehara, Japan
⁶Division of Genome Sciences, Institute of Medical Sciences, Tokai University, Isehara, Japan
⁷Division of Interdisciplinary Merging of Health Research, Micro/Nano Technology Center, Tokai University, Hiratsuka, Japan

Ken Phong Phong Dao^1*, Alyssa Obermayer, MS^2*, Joshua Davis, PharmD, PhD^3*, Qiangxing Mo, PhD^4*, Mingxiang Teng, PhD^3*, Eric Padron, MD⁵ and Timothy Shaw, PhD⁶

¹University of South Florida, College of Arts and Sciences, Tampa, Florida 33612, Tampa, FL
²H Lee Moffitt Cancer Center, Tampa, FL
³Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center, Tampa, FL
⁴Moffitt Cancer Center, Tampa, FL
⁵Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁶H. Lee Moffitt Cancer Center, Tampa, FL

Eduardo Sabino De Camargo Magalhaes, MD, PhD^1*, Brandon D. Brown, MD^2*, Yihua Qiu, MD^3* and Steven M. Kornblau, MD³

¹Department of Ageing Biology/ERIBA, University Medical Center Groningen, Groningen, Netherlands
²Department of Pediatrics, MD Anderson Cancer Center, Houston, TX
³Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Thinzar Koko, MRCP, FRCPath¹, Grzegorz Pietka, PhD^2*, Louise Howell^3*, Alison McCormick, DipRCPath^4*, Tracy Thornton^4*, Elisa Garimberti^4*, Farideh Miraki-Moud, PhD^5* and David Taussig, PhD, MRCP, FRCPath⁶

¹Haematology, Institute of Cancer Research/ Royal Marsden Hospital, London, United Kingdom
²Molecular Pathology, Institute of Cancer Research, London, United Kingdom
³Core Research Facilities- Light Microscopy, Institute of Cancer Research, London, United Kingdom
⁴Cytogenetics, Royal Marsden Hospital, London, United Kingdom
⁵Acute Leukaemia Team, Institute of Cancer Research, London, United Kingdom
⁶The Royal Marsden Hospital and Institute of Cancer Research, London, United Kingdom

Ryan D Chow, PhD^1*, Priya Velu, MD^2*, Safoora Deihimi, MS^3*, Jonathan Belman, MD PhD^3*, Angela Youn, BA^4*, Nisargbhai Shah, MS^4*, Jennifer JD Morrissette, PhD^3* and Robert L. Bowman, PhD⁵

¹Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
²Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY
³School of Medicine, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA
⁴Cancer Biology Department, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
⁵Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

Lu Yu^1*, Lijuan Hu^2*, Zongru Li, MD^3*, Ting Zhao^4*, Wenbing Duan^5*, Jing Wang^6*, JinSong Jia, MD^6*, Jing Liu, MD^7*, Ya-Zhen Qin, MD^3*, Hao Jiang^3*, Xiaohui Zhang, MD⁸, Feifei Tang^9*, Yuqian Sun^10*, XiaoDong Mo, MD^11*, LanPing Xu, MD^12*, Yu Wang^13*, Xiaojun Huang^7* and Qian Jiang, MD¹⁴

¹National Clinical Research Center for Hematologic Disease, Peking University People’s Hospital, Peking University Institute of Hematology, Beijing, China
²National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Peking University People’s Hospital, Peking University Institute of Hematology, Beijing, China
³Peking University People’s Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
⁴Peking University People’s Hospital, Peking University Institute of Hematology National Clinical Research Center for Hematologic Disease, China, Beijing, China
⁵Department of Hematology, Peking University People's Hospital, Beijing, China
⁶Peking University People’s Hospital,Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing, China
⁷Peking University People’s Hospital, Beijing, China
⁸Peking University People's Hospital, Beijing, China
⁹Peking University People’s Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, AL, China
¹⁰National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
¹¹Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
¹²Peking University People’s Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing, China
¹³Peking University People’s Hospital, Peking University Institute of Hematology, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, National Clinical Research Center for Hematologic Disease, Beijing, China
¹⁴Peking University People's Hospital, Peking University Institute of Hematology, Beijing, China

Eric McGinnis, MD, FRCPC^1,2, Ryan J Stubbins, MD, MSc, FRCPC³, Dan Li, MB, PhD, FCCMG, MLT^1,2*, Zeid Hamadeh, PhD^1,2* and Tara J Spence, PhD, FCCMG, FACMG^1,2*

¹Department of Pathology and Laboratory Medicine, Vancouver General Hospital, Vancouver, BC, Canada
²Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada
³Department of Medicine, Division of Hematology, University of British Columbia, Leukemia Bone Marrow Transplant Program of British Columbia and Vancouver General Hospital, Vancouver, BC, Canada, Vancouver, Canada

Luise Araujo De Albuquerque Simoes, BS^1,2,3,4*, Isabel Weinhäuser, PhD^3,5*, Diego A Pereira-Martins, PhD^3,5*, Luciana Yamamoto Almeida, PhD^2*, Vincent Van Den Boom, Ph.D.^3*, Fatemeh Mojallali, MSc^3*, Dominique Sternadt^3*, Prodromos Chatzikyriakou, Ph.D.^5*, Xuesen Zheng, PhD^6*, César Alexander Ortiz Rojas, Ph.D.^1,2*, Ghulam Jeelani Mufti, MB, DM, FRCP, FRCPath^5*, Lucio Henrique Pinheiro, MSc^1,2,4*, Lynn Quek, MD, Ph.D.^5*, Gerwin A. Huls, Prof.³, Eduardo M. Rego, MD, PhD^2,4,7 and Jan Jacob Schuringa, Prof. Dr.³

¹Laboratory of Medical Investigation in Pathogenesis and Targeted Therapy in Onco-Immuno-Hematology (LIM-31), Department of Internal Medicine, Hematology Division, University of São Paulo Medical School, Sao Paulo, Brazil
²Department of Internal Medicine, Medical School of Ribeirao Preto and the Center for Cell Based Therapy, University of São Paulo, Ribeirao Preto, Brazil
³Department of Experimental Hematology, University Medical Center Groningen, Groningen, Netherlands
⁴Department of Hematology, Institute of Cancer of Sao Paulo, Sao Paulo, Brazil
⁵Myeloid Leukaemia Genomics and Biology Group, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom
⁶Myeloid Leukaemia Genomics and Biology Group, School of Cancer and Pharmaceutical Sciences, King's College London, London, ENG, United Kingdom
⁷Laboratory of Medical Investigation in Pathogenesis and Targeted Therapy in Onco-Immuno-Hematology (LIM-31), Department of Internal Medicine, Hematology Division, University of São Paulo Medical School, São Paulo, São Paulo, Brazil

Dakshin Padmanabhan, MBBS¹, Jeff Aguilar, MD, MBA^2*, Paul Kim, BA^2*, Sandhya Dhiman², Asmita Shukla, MD³, Vikram Dhillon, DO, MBA^4*, Sushmitha Nanja Reddy, MD, MBBS⁵, David Carr, MD^3*, Jay Yang, MD³, Julie Boerner^3*, Jaroslaw Maciejewski⁶ and Suresh Kumar Balasubramanian, MD^6,7

¹Internal Medicine, Trinity Health Oakland Hospital, Rochester Hills, MI
²Karmanos Cancer Institute/Wayne State University, Detroit, MI
³Department of Oncology, Karmanos Cancer Institute/Wayne State University, Detroit, MI
⁴Department of Hematology/Oncology, Neal Cancer Center/Houston Methodist Hospital, Detroit, MI
⁵Department of Oncology, Karmanos Cancer Institute/Wayne State University, Novi, MI
⁶Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
⁷Department of Oncology, Karmanos Cancer Institute/Wayne State University, Troy, MI

Elisabetta Todisco^1*, Martina Fontanini Jr.^2*, Chiara Ronchini^2*, Raffaella Furgi^2*, Yinxiu Zhan^2*, Viviana Amato^3*, Alessandro Davini^3*, Ramadan Safaa Mahmoud^3*, Federica Gigli, MD^3*, Fabio Giglio^3*, Gabriella Parma^4*, Nicoletta Colombo^4*, Samuele Gatani Jr.^1*, Alessandro Rambaldi⁵, Enrico Derenzini, MD, PhD^6*, Corrado Tarella^7*, Pier Giuseppe Pelicci, MD, PhD^8* and Myriam Alcalay Sr., MD, PhD^9*

¹Hematology, ASST Valle Olona, Ospedale di Busto Arsizio, Busto Arsizio, Italy
²DIMA Laboratory, IEO, European Institute of Oncology IRCCS, Milan, Italy
³Onco-Hematology Division, IEO, European Institute of Oncology IRCCS, Milan, Italy
⁴Department of Gynecology, IEO, European Institute of Oncology IRCCS, Milan, Italy
⁵Hematology and Bone Marrow Transplant Unit, ASST Papa Giovanni XXIII, Bergamo, Italy
⁶European Institute of Oncology, Milan, Italy
⁷Onco-Hematology Division, IEO European Institute of Oncology IRCCS, Milan, AL, Italy
⁸Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy
⁹Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, ITA

David Chen, BS¹, Suraj Bansal^1,2*, Amanda Mitchell, PhD^1*, Anne Maria Tierens, MD, PhD³, Andy G.X. Zeng, BSc¹ and John E. Dick, PhD¹

¹Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
²University Health Network, Toronto, ON, Canada
³Laboratory Medicine Program, Toronto General Hospital, University Health Network, Toronto, Canada

Vivek M. Shastri, PhD¹, Francisco Marchi, BS¹, Michael R. Loken, PhD^2* and Jatinder K. Lamba, PhD^1,3

¹Department of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, FL
²Hematologics, Inc., Seattle, WA
³UF Health Cancer Center, University of Florida, Gainesville, FL

Min Fang, MD, PhD¹, Zahra Shamsi, Ph.D.^2*, Drew Bryant^3*, Jacob Wilson^1*, Xiaoyu Qu, PhD^1*, Avinava Dubey^2*, Konik Kothari^2*, Mostafa Dehghani^2*, Mariya Chavarha^2*, Valerii Likhosherstov^2*, Brian Williams^2*, Michael Frumkin^2*, Frederick R. Appelbaum, MD¹, Krzysztof Choromanski^2* and Ali Bashir^2*

¹Fred Hutchinson Cancer Center, Seattle, WA
²Google Research, Mountain View, CA
³Google Research, Mountain View

Qiwei SUN^1*, Kathy Yuen Yee Chan, PhD^2*, Chi Kong Li² and Kam Tong Leung^2*

¹Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong, Hong Kong
²Department of Paediatrics, The Chinese University of Hong Kong, Shatin, Hong Kong

Shyam Ajay Patel, MD, PhD¹, Salwa Khedr, MD^1*, Caroline D Gordon, MD^1*, Noah Littman^1*, Bruce Woda, MD¹, Lloyd Hutchinson, PhD^1*, Jan Cerny, MD, PhD¹, Shaoguang Li, MD, PhD², William Selove^3* and Jonathan M. Gerber, MD⁴

¹UMass Chan Medical School, Worcester, MA
²Univ. of Massachusetts Chan Medical School, Worcester, MA
³UMass Memorial Medical Center, Whitinsville, MA
⁴Division of Hematology/Oncology, Department of Medicine, NYU Langone Health, New York, NY

Shu Sun^1*, Yongjing Liu^2*, Qing-Yu Xu^1*, Xiaosu Zhou, PhD^3*, Lijun Wen, MD^4*, Li Chen, MD^5*, Jiaqi Chen, PhD^3,6*, Huili Wang^7*, Xue Chen, MD^6*, Jiacheng Lou^5*, Huyong Zheng⁸, Yangyang Xie^9*, Linya Wang^8,10,11,12*, Futian Ma, MD, PhD^13*, Lihua Yang, MD^14*, Xianjing Wang^7*, Wen Gao¹, Yin Wu, MD^1*, Leping Zhang^15*, Shuhong Shen⁹, Suning Chen, MD, PhD^4*, Kankan Wang, MD, PhD^5*, Hongxing Liu, MD^16,17, Jinyan Huang^2* and Hong-Hu Zhu^1,18*

¹Department of Hematology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
²Biomedical big data center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
³Beijing Lu Daopei Institute of Hematology, Molecular Medicine Center, Beijing, China
⁴National Clinical Research Center for Hematologic Diseases, The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China
⁵Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
⁶Department of Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Langfang, China
⁷Department of Hematology, The Third People's Hospital of Zhengzhou, Zhengzhou, China
⁸Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Hematology Center, Beijing, China
⁹Department of Hematology , Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
¹⁰Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China
¹¹National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University), Beijing, China
¹²Hematology Center, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology, Beijing, China
¹³Department of Hematology, Hebei Children's Hospital, Shijiazhuang, China
¹⁴Pediatric Hematology, Zhujiang Hospital, Southern Medical University, Pediatric Hematology, Guangzhou, CHN
¹⁵Department of Pediatrics, Peking University People's Hospital, Beijing, China
¹⁶Department of Laboratory Medicine, Lu Daopei Hematology & Oncology Center, Hebei Yanda Hospital, Langfang, China
¹⁷Pathology & Laboratory Medicine Division, Beijing Lu Daopei Institute of Hematology, Pathology & Laboratory Medicine Division, Beijing, China
¹⁸Chinese Institutes for Medical Research, Beijing, China

Romika Kumari, PhD^1*, Juho J. Miettinen, PhD^1*, Mahesh B. Tambe, PhD^1*, June Olgac, MSc^1*, Tanja Ruokoranta, MSc^1*, Nemo Ikonen, MSc^1*, Minna H. Suvela^1*, Maiju-Emilia Huppunen, MSc^1*, Stefan Svensson Gelius, PhD^2*, Klara Acs, PhD^2* and Caroline A. Heckman, PhD¹

¹Institute for Molecular Medicine Finland – FIMM, HiLIFE – Helsinki Institute of Life Science, iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland
²Oncopeptides AB, Stockholm, Sweden

Ming Hong, MD, PhD^1*, Bin Huang, Master^2*, Wenjie Liu, M.D.;Ph.D.^1*, Qian Sun, M.D.;Ph.D.^1*, Jianyong Li, MD³, Sixuan Qian^4*, Qianghu Wang, PhD^5* and Kening Li^5*

¹Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
²Department of Bioinformatics, School of Biomedical Engineering and Informatics,, Nanjing Medical University, Nanjing, China
³First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
⁴Jiangsu Province Hospital, Nanjing, China
⁵Department of Bioinformatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China

Priyanka Rajesh Ugale, MSc^1*, Aarti Ramesh Achrekar, MSc^1*, Seema Biswas, MD^1*, Swapnali Joshi, MSc^1*, Vishram Terse, PhD, MSc^1*, Dhanlaxmi Lalit Shetty, PhD, MSc^2,3*, Nishant Jindal, MD, MBBS^4,5*, Prashant Tembhare, MD^6*, Sumeet Mirgh, MD, DM^4,7,8*, Alok Shetty, MD, DM^9*, Anant Gokarn, MD, DM^4,9,10,11*, Sachin Punatar, MD, DM^4,9,10,11*, Hasmukh Jain, MD, DM^12*, Lingaraj Nayak, MBBS, MD, DM^4,9,10,13*, Manju Sengar, MD, DM¹², Navin Khattry, MD, DM^7,10*, Bhausaheb Bagal, MD, DM^10*, Sweta Rajpal, MD, DM^1*, Gaurav Chatterjee, MD, MSc^1*, PG Subramanian, MD^1*, Sumeet Gujral, MD^14* and Nikhil Patkar, MD^1*

¹Department of Hematopathology, ACTREC, Tata Memorial Centre, Navi Mumbai, India
²Cancer Cytogenetics, ACTREC, Tata Memorial Centre, Navi Mumbai, India
³Tata Memorial Hospital, Mumbai, India
⁴Homi Bhabha National Institute, Mumbai, India
⁵Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Chandigarh, India, India
⁶Department of Hemato Pathology, Tata Memorial Centre, Mumbai, India
⁷Department of Medical Oncology, ACTREC, Tata Memorial Centre, Navi Mumbai, India
⁸Department of Medical Oncology, ACTREC, Tata Memorial Centre, Mumbai, India
⁹Department of Medical Oncology, Tata Memorial Centre, Mumbai, India
¹⁰Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Navi Mumbai, India
¹¹BMT unit, Department of Medical Oncology, Tata Memorial Centre, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Homi Bhabha National Institute, Navi Mumbai, India
¹²Department of Medical Oncology, Tata Memorial Hospital, Mumbai, India
¹³Department of Medical Oncology, Tata Memorial Centre, MUMBAI, India
¹⁴Department of Pathology, Tata Memorial Centre, Mumbai, India

Jacob Todd^1*, Grant Hogg, MSc^1*, Kimberly Holden^1*, Adib Shafi, Ph.D.^1*, Tong Liu^1*, Kerry Fitzgerald, Ph.D.^1*, Yuanyu (Helen) Cao, Ph.D.^1*, Ashraf Shabaneh^1*, John Howitt^2*, Amanda Williamson^2*, Xiaojun Guan, Ph.D.^1*, Qian Zeng, Ph.D.^3*, Michael Mooney^2*, Henry Y. Dong, MD, PhD⁴, Stanley Letovsky, Ph.D.^3*, Li Cai^2*, Eric A Severson, M.D., Ph.D.^2*, Shakti H Ramkissoon, M.D., Ph.D.^2*, Anjen Chenn, M.D., Ph.D.^2*, Marcia Eisenberg, Ph.D.^5*, Eyad Almasri, Ph.D.^1*, Taylor J Jensen, PhD^1* and Jonathan Williams, Ph.D.^1*

¹Labcorp, San Diego
²Labcorp, Durham
³Labcorp, Westborough
⁴Labcorp, New York
⁵Labcorp, Burlington

Adrian Mosquera Orgueira, MD, PhD^1*, Manuel Perez Encinas, MD^2*, Carlos Pérez Míguez^3*, Rebeca Rodriguez Veiga, MD, PhD^4*, Juan Miguel Bergua Burgues, MD^5*, Jesus Lorenzo Algarra^6*, Carmen Botella^7*, Jose Antonio Perez Simon^8*, Teresa Bernal^9,10,11*, Mar Tormo, MD^12*, Maria Calbacho, MD^13*, Olga Salamero, MD^14,15*, Josefina Serrano, MD^16*, Victor Noriega^17*, Juan Antonio Lopez Lopez^18*, Susana Vives, MD^19*, Mercedes Colorado, MD^20*, Jose Luis Lopez Lorenzo, MD^21*, Maria Vidriales Vicente^22*, Raimundo Garcia Boyero, MD^23*, Maria Teresa Olave Rubio^24*, Pilar Herrera Puente^25*, Olga Arce, MD^26*, Manuel Barrios Garcia^27*, Maria Jose Sayas Lloris, MD^28*, Marta Polo, MD^29*, Maria Isabel Gomez Roncero^30*, Eva Barragán, PhD^31*, Rosa Ayala, MD, PhD^32*, Carmen Chillon, MD^33*, Maria Jose Calasanz, PhD^34*, Blanca Boluda^35*, Andres Peleteiro Raindo^36*, Raquel Amigo^37*, David Martinez-Cuadron, PhD³⁸, Jorge Labrador, MD^39* and Pau Montesinos, PhD, MD^40*

¹University Hospital of Santiago de Compostela, Department of Hematology, IDIS, SANTIAGO DE COMPOSTELA, Spain
²Department of Hematology, Hospital Unviersitario de Santiago de Compostela, IDIS, Santiago de Compostela, ESP
³University Hospital of Santiago de Compostela, Department of Hematology, Santiago de Compostela, Spain, Santiago de Compostela, Spain
⁴Hospital Universitary i Politecnic La Fe, Valencia, ESP
⁵Hospital San Pedro de Alcántara, Caceres, Spain
⁶6. Hospital General de Albacete, Albacete, Spain
⁷Hospital General Universitario de Alicante, Alicante, Spain
⁸University Hospital Virgen del Rocío, Sevilla, Spain
⁹Hospital Universitario Central de Asturias, Oviedo, Spain
¹⁰Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Asturias, Spain
¹¹Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Asturias, Spain
¹²Department of Hematology, Hospital Clínico de Valencia, Valencia, Spain
¹³Hematology Department, Hospital Universitario 12 de Octubre, Madrid, Madrid, Spain
¹⁴Hematology Department, University Hospital Vall d’Hebron, Barcelona, Spain
¹⁵Experimental Hematology, Vall d’Hebron Institute of Oncology, Barcelona, Spain
¹⁶Department of Hematology, Hospital Universitario Reina Sofía, IMIBIC.UCO, Cordoba, ESP
¹⁷Hospital Clínico de A Coruña, A Coruña, Spain
¹⁸Hospital Universitario de Jaen, Jaen, Spain
¹⁹Hematology Department, Institut Catala d'Oncologia - Hospital Germans Trias i Pujol, Badalona, Spain
²⁰Hematology Department, University Hospital Marques de Valdecilla, Santander, Spain
²¹Fundacion Jimenez Diaz, Madrid, ESP
²²Hospital Universitario de Salamanca, Salamanca, Spain
²³Hospital General Universitario de Castellon, Castellon, Spain
²⁴Hospital Clinico Universitario Lorenzo Blesa, Zaragoza, ESP
²⁵Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain
²⁶Hospital Universitario de Basurto, Bilbao, Spain
²⁷Hospital Universitario Regional de Malaga, Malaga, Spain
²⁸Hospital Dr. Peset, Valencia, Spain
²⁹Department of Hematology, Hospital Universitario Clinico San Carlos, Madrid, Spain
³⁰Hospital Virgen de la Salud, Toledo, Spain
³¹Department of Hematology, Instituto de Investigación Sanitaria La Fe, Valencia, Spain
³²Hospital Universitario 12 De Octubre, Madrid, Spain
³³Haematology Department, University Hospital of Salamanca, Research Biomedical Institute of Salamanca (IBSAL), CIBERONC and Center for Cancer Research-IBMCC (USAL-CSIC), Salamanca, Spain
³⁴Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), IDISNA, CIBER-ONC number CB16/12/00369 and CB16/12/00489, Pamplona, Spain
³⁵Hospital Universitari I Politècnic La Fe, Valencia, ESP
³⁶University Hospital of Santiago De Compostela, Department of Hematology, IDIS, SANTIAGO DE COMPOSTELA, ESP
³⁷Instituto de Investigaciones Santiarias La Fe, Valencia, Spain
³⁸Hematology, Instituto de Investigación Sanitaria La Fe, Valencia, Spain
³⁹Department of Hematology, Hospital Universitario de Burgos, Universidad Isabel I, Burgos, Spain
⁴⁰Hematology, Hospital Universitari I Politécnic La Fe and Programa Español de Tratamientos en Hematología (PETHEMA) Group, Valencia, Spain

Maria Rita Khouri, MD^1*, Bofei Wang, PhD², Poorva Bindal, MD³, Sakiko Suzuki, MD¹, Lloyd Hutchinson, PhD^4*, Laurie K Pearson, MD⁵, Andrew Gillis-Smith, MD¹, Jan Cerny, MD, PhD⁴, Muthalagu Ramanathan, MD¹, Jonathan M. Gerber, MD⁶ and Shyam Ajay Patel, MD, PhD⁷

¹Division of Hematology/Oncology, Department of Medicine, University of Massachusetts Memorial Medical Center, Worcester, MA
²Division of Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
³Division of Hematology/Oncology, Department of Medicine, UMass Chan Medical School, Grafton, MA
⁴UMass Chan Medical School, Worcester, MA
⁵UMass Memorial Medical Center, Department of Medicine, Waltham, MA
⁶Division of Hematology/Oncology, Department of Medicine, NYU Langone Health, New York, NY
⁷Division of Hematology/Oncology, University of Massachusetts Memorial Medical Center, Worcester, MA

Juliana Alvarez Argote, MD¹, Kristin E Zorn, MD², Cary Stelloh^3*, Alison E Meyer, PhD⁴, Maria E Hintzke, MD^5*, Ashley Cunningham, MD^5*, Emily Giever, MSN, RN^6*, George S Vassiliou, MD, PhD⁷, Ehab L. Atallah, MD⁸ and Sridhar Rao, MD, PhD⁹

¹Medicine, Hematology-Oncology, Medical College of Wisconsin, Pewaukee, WI
²Pediatric Hematology/Oncology, Phoenix Children's Hospital, Phoenix, AZ
³Versiti Blood Research Institute, Milwaukee, WI
⁴Versiti Blood Research Institute, Brookfield, WI
⁵Department of Pathology, Medical College of Wisconsin, Milwaukee, WI
⁶Division of Hematology/Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI
⁷Department of Haematology and Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom
⁸Division of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI
⁹Hematopoiesis & Stem Cell Biology Program, Versiti Blood Research Institute, Milwaukee, WI

John N Colgan, MD^1,2,3, Jack H. Peplinski, MSc^4*, Danielle C. Kirkey, MD^1,4, Adam Lamble, MD¹, Rhonda E. Ries, MA^4* and Soheil Meshinchi, MD, PhD^1,4

¹Department of Pediatrics, University of Washington, Seattle, WA
²School of Clinical Medicine, UNSW, Children's Cancer Institute, Kensington, NSW, Australia
³Translational Sciences and Therapeutics, Fred Hutchinson Cancer Center, Seattle, WA
⁴Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle, WA

Jinjuan Yao^1*, Umut Aypar, PhD^1*, Shenon Sethi, MBBS^1*, Leora Boussi, MD², Dory Londono^1*, Purvil Sukhadia^1*, Ellin Berman, MD³, Eytan M. Stein, MD⁴, Ahmet Dogan, MD, PhD⁵, Wenbin Xiao, MD, PhD⁶ and Yanming Zhang, MD¹

¹Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
²Department of Medicine; Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
³Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁴Department of Medicine; Leukemia Service, Memorial Sloan-Kettering Cancer Center, New York, NY
⁵Memorial Sloan Kettering Cancer Center, New York, NY
⁶Department of Pathology and Laboratory Medicine, Hematopathology Service, Memorial Sloan Kettering Cancer Center, New York, NY

Ji Ma, MD, PhD^1*, Qiang He, MD^1*, Qian Wu, MD^1*, Lili Feng, MD, PhD^1*, Y. Lynn Wang, MD, PhD² and Linna Xie, MD, PhD^1*

¹Department of Hematology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China
²Fox Chase Cancer Center, Philadelphia, PA

Amanda Halfond, MSc^1*, Matthew H Ung, PhD^2*, Julia Etchin, PhD^1*, Julia DiFazio^1*, Yonina Keschner^1*, Mariana Silva, PhD^1*, Alyssa Pyclik^1*, Antonino Montalbano, PhD^1*, Ermin Zhao, PhD^1*, Guy Mundelboim^1*, Julian Scherer, PhD^1*, Huanying Gary Ge, PhD^1*, John R Lydeard, PhD¹ and Tirtha Chakraborty, PhD^1*

¹Vor Bio, Cambridge, MA
²Quantitative Biology, Vor Bio, Cambridge, MA

Baher Krayem, MD^1*, Nivin moustafa-Hawash^2*, Avraham Frisch, MD^3*, Christina Srouji^4* and Tsila Zuckerman, MD^5,6

¹Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Rappaport Faculty of Medicine - Technion, Haifa, Israel
²Rambam Health Care Campus, Haifa, Israel
³Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel
⁴Rambam, haifa, Israel
⁵Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Moshav Ein Ayalla, Israel
⁶Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel

Joseph Saad, MSc^1*, Rhiannon Newman^2*, Elmira Khabusheva, PhD^3*, Sofia Aakko, PhD^4,5*, Eric Durand, PhD^6*, Mahesh B. Tambe, PhD^7*, Heikki Kuusanmäki, PhD^8*, Alun Parsons, MSc^9*, Juho J. Miettinen, PhD^7*, Komal Kumar Javarappa, PhD^4*, Nemo Ikonen, MSc^9*, Mika Kontro, MD, PhD^9,10,11, Kimmo Porkka, MD, PhD¹⁰, Heiko Maacke, MD, PhD^12*, Janghee Woo, MD, PhD¹³, Ensar Halilovic, PhD^14* and Caroline A. Heckman, PhD¹⁵

¹Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Uusimaa, Finland
²Institute of Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science, iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, AL, Finland
³Institute for Molecular Medicine Finland - FIMM, Helsinki Institute of Life Science, iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland
⁴Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), iCan Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, FIN
⁵Faron Pharmaceuticals, Turku, Finland
⁶PhD, Novartis Biomedical Research, Basel, Switzerland, Basel, CHE
⁷Institute for Molecular Medicine Finland – FIMM, HiLIFE – Helsinki Institute of Life Science, iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland
⁸Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland
⁹Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), iCan Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland
¹⁰Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland
¹¹Foundation for the Finnish Cancer Institute, Helsinki, Finland
¹²TCO Clinical, Novartis Biomedical Research, Basel, Switzerland
¹³Winship Cancer Institute of Emory University, Atlanta, GA
¹⁴OTR, Biomedical Research, Novartis Pharmaceuticals Corporation, Cambridge, MA
¹⁵Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland

Jingliao Zhang, MD¹, Peng Wu^2*, Yongjuan Duan^3*, Suyu Zong^4*, Xiaoli Chen^5*, Tianyuan Hu^6*, Wenyu Yang, MD^7*, Renchi Yang, MD⁸ and Yingchi Zhang^9*

¹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology& Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
²State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Tianjin, China
³State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical Co, Tianjin, CHN
⁴State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Tianjin, China
⁵State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, CAMS & PUMC, Tianjin, CHN
⁶State Key Laboratory of Experimental Hematology, National Clinical Research Cent, Tianjin, CHN
⁷Department of Pediatric Hematology and Oncology, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology& Blood Diseases Hospital, Chinese Academy of Medical Sciences& Peking Union Medical College, Tianjin, China
⁸Department of Pediatric Hematology and Oncology, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China
⁹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, CAMS & PUMC, Tianjin, China

Jack H. Peplinski, MSc^1*, Logan K. Wallace, MSc^1*, Rhonda E. Ries, MA^2*, Xiaotu Ma, PhD³, Danielle C. Kirkey, MD¹ and Soheil Meshinchi, MD, PhD¹

¹Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle, WA
²Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA
³St. Jude Children's Research Hospital, Memphis, TN

Silvia Schäfer^1,2*, Lola Schmitz-Hübsch^1,2*, Mehak Nihal Shaikh^3,4*, Silke Brilloff^1,2*, Elahe Rahimian^1,2*, Vida Kufrin^1,2*, Sandra Küchler^1,2*, Maria Fedorova, PhD^5*, Dominic Helm, PhD^6*, Claudia R Ball, PhD^2,7,8,9*, Martin Bornhäuser, MD^1,10*, Hanno Glimm, MD^2,7,8,11, Meritxell Alberich Jorda, Ph.D.^3,12*, Marius Bill, MD, PhD^1,2,7,10* and Alexander A Wurm, PhD^1,2,7,8*

¹Mildred Scheel Early Career Center, National Center for Tumor Diseases (NCT/UCC) Dresden, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University, Dresden, Germany
²Department for Translational Medical Oncology, National Center for Tumor Diseases Dresden (NCT/UCC), a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and HZDR, Dresden, Germany
³Laboratory of Hemato-oncology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic
⁴Faculty of Science, Charles University, Prague, Czech Republic
⁵Center of Membrane Biochemistry and Lipid Research, University Hospital and Faculty of Medicine Carl Gustav Carus of TU Dresden, Dresden, Germany
⁶Proteomics Core Facility, German Cancer Research Center (DKFZ), Heidelberg, Germany
⁷German Cancer Consortium (DKTK), partner site Dresden, Dresden, Germany
⁸Translational Medical Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany
⁹TUD Dresden University of Technology, Faculty of Biology, Dresden, Germany
¹⁰Department of Internal Medicine 1, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany
¹¹Translational Functional Cancer Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany
¹²Childhood Leukaemia Investigation Prague, Department of Pediatric Haematology and Oncology, 2nd Faculty of Medicine, Charles University in Prague, University Hospital Motol, Prague, Czech Republic

Uma Borate, MD¹, Rina Li Welkie, MPH², Ying Huang, MS, MA³, Ronan T. Swords, MD, PhD, FRCP, FRCPath⁴, Elie Traer, MD, PhD⁴, Eytan M. Stein, MD⁵, Tara L. Lin, MD⁶, Yazan F Madanat, MD⁷, Prapti A. Patel, MD⁸, Robert H. Collins, MD⁷, Maria R. Baer, MD⁹, Vu H. Duong, MD, MS¹⁰, William Blum, MD¹¹, Martha L. Arellano, MD¹², Wendy Stock, MD¹³, Olatoyosi Odenike, MD¹³, Robert L. Redner, MD¹⁴, Tibor J. Kovacsovics, MD¹⁵, Michael W. Deininger, MD, PhD¹⁶, Joshua F. Zeidner, MD¹⁷, Rebecca Olin, MD¹⁸, Catherine C. Smith, MD¹⁹, James M. Foran, MD²⁰, Gary J. Schiller, MD²¹, Emily K Curran, MD²², Kristin L Koenig, MD²³, Nyla A. Heerema, PhD^24*, Timothy Chen, PhD¹, Molly Martycz^1*, Mona Stefanos, MD²⁵, Sonja Gullen Marcus, MPH^26*, Leonard Rosenberg^26*, Brian J. Druker, MD⁴, Ross L Levine, MD²⁷, Amy Burd, PhD²⁸, Ashley Owen Yocum, PhD²⁶, Alice Mims, MD²⁹ and John C. Byrd, MD³⁰

¹The Ohio State University, Columbus, OH
²The Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH
³Division of Hematology, Department of Statistics, The Ohio State University Wexner Medical Center, Columbus, OH
⁴Knight Cancer Institute, Oregon Health & Science University, Portland, OR
⁵Department of Medicine; Leukemia Service, Memorial Sloan-Kettering Cancer Center, New York, NY
⁶Division of Hematologic Malignancies and Cellular Therapeutics, The University of Kansas Cancer Center, Westwood, KS
⁷Division of Hematology/Oncology, Department of Internal Medicine, University of Texas Southwestern, Dallas, TX
⁸Servier Pharmaceuticals LLC, Boston, MA
⁹University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD
¹⁰University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD
¹¹Emory University, Winship Cancer Institute, Atlanta, GA
¹²Emory University, Atlanta, GA
¹³Department of Medicine, Section of Hematology/Oncology, University of Chicago, Chicago, IL
¹⁴University of Pittsburgh Medical Center, Pittsburgh, PA
¹⁵University of Utah, Salt Lake City, OR
¹⁶Versiti Blood Research Institute, Milwaukee, WI
¹⁷Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC
¹⁸University of California San Francisco, San Francisco, CA
¹⁹Department of Medicine, Division of Hematology/Oncology, University of California, San Francisco, San Francisco, CA
²⁰Division of Hematology & Medical Oncology, Mayo Clinic, Jacksonville, FL
²¹David Geffen School of Medicine at UCLA, Los Angeles, CA
²²University of Cincinnati, Cincinnati, OH
²³Division of Hematology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH
²⁴Ohio State University, Columbus, OH
²⁵The Ohio State University, Lewis Center, OH
²⁶Leukemia and Lymphoma Society, Rye Brook, NY
²⁷Memorial Sloan Kettering Cancer Center, New York, NY
²⁸Leukemia and Lymphoma Society, White Plains, NY
²⁹The Ohio State University Comprehensive Cancer Center, Columbus, OH
³⁰Department of Internal Medicine, University of Cincinnati, Cincinnati, OH

Nona Struyf^1*, Henrik Gezelius, PhD^2*, Anders Lundmark^3*, Chiara Barizza^1*, Hidde Ploeger^1*, Lucía Rico Pizarro^1*, Mattias Vesterlund, PhD, MSc^1*, Georgios Mermelekas^1*, Albin Osterroos, MD^4*, Anna Bohlin^5*, Sofia Bengtzén^6*, Kerstin Hamberg Levedahl^7*, Rozbeh Jafari, PhD^1*, Lukas M Orre^1*, Janne Lehtiö, PhD^8*, Päivi Östling^1*, Brinton Seashore-Ludlow^1*, Jessica Nordlund, PhD^3*, Soren Lehmann, MD, PhD^4,9*, Olli Kallioniemi^1,10* and Tom Erkers^1*

¹Department of Oncology-Pathology and Science for Life Laboratory, Karolinska Institute, Stockholm, Sweden
²Med, Uppsala University, Uppsala, Sweden
³Department of Medical Sciences and Science for Life Laboratory, Uppsala University, Uppsala, Sweden
⁴Department of Medical Sciences, Hematology, Uppsala University, Uppsala, Sweden
⁵Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden
⁶Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institute, Stockholm, Sweden
⁷Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
⁸Department of Oncology-Pathology and Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden
⁹Center for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institute, Stockholm, Sweden
¹⁰FIMM, University of Helsinki, Helsinki, Finland

Melissa L Stewart, PhD^1*, Jessica Gibbs^1*, Daniel Bottomly^2*, Andy Kaempf, MS^3*, Stephen E. Kurtz, PhD^1*, Christopher A. Eide^1*, Ariane Huang, BS^4*, Luca Sax, BSc^5*, Nicola Long^4*, Shannon K McWeeney, PhD^1*, Bill H Chang, MD PhD⁶ and Jeffrey W. Tyner, PhD⁴

¹Knight Cancer Institute, Oregon Health and Science University, Portland, OR
²Knight Cancer Institute, Oregon Health and Sciences University, Portland, OR
³Knight Cancer Institute, Biostatistics Shared Resource, Oregon Health & Science University, Portland, OR
⁴Knight Cancer Institute, Oregon Health & Science University, Portland, OR
⁵Knight Cancer Institute, Oregon Health and Science university, Portland, OR
⁶Doernbecher Children's Hospital, Oregon Health & Science University, Portland, OR

Krishna Ghimire, MD¹, Alexandra Goodman, MD², Parth Sampat, MBBS¹, Nimisha Srivastava, MD^1*, Myungwoo Nam, MD^1* and Jeffrey Ross, MD^3*

¹Department of Hematology/Oncology, SUNY Upstate Medical University, Syracuse, NY
²Department of Hematology/Oncology, SUNY Upstate University, Syracuse, NY
³Department of Anatomic and Clinical Pathology, SUNY Upstate Medical University, Syracuse, NY