Lei Ju, Dr^1*, Xingli Zhao^2,3*, Xiaohui Suo^4*, ZePing Zhou, MD, PhD⁵, Yanliang Bai, MD^6*, Yunya Luo^7*, Sifeng Gao^8*, Xinxiao Lu^3*, Linyu Yuan^3*, Congcong Zhang^9*, Yinling Li^9*, Yaxian Tan^10*, Guanchen Bai^8*, Hongling Peng, MD^11*, Pengxiang Guo^12*, Yingchang Mi, MD¹³ and Kaiqi Liu^13*

¹Department of Hematology, The Affiliated Tai'an City Central Hospital of Qingdao University, Taian, Shandong, China, 271000., Tai'an, China
²Tianjin People's Hospital, Tianjin, China
³Department of Hematology, Oncology Center, Tianjin People's Hospital, No. 190 jieyuan Road, Hongqiao District, Tianjin 300121, P R China., Tianjin, China
⁴Department of Hematology, Handan Central Hospital, Handan, Hebei, China., Handan, China
⁵Second Affiliated Hospital of Kunming Medical University, Kunming, China
⁶Department of Hematology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou, China
⁷Department of Hematology, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, People's Republic of China., Changsha, China
⁸Department of Hematology, The Affiliated Tai'an City Central Hospital of Qingdao University, Taian, Shandong, China, 271000., Taian, China
⁹Department of Hematology, Handan Central Hospital, Handan, Hebei, China, 056000,, Handan, China
¹⁰Department of Hematology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China, Kunming, China
¹¹Department of hematology, The second xiangya hospital of Central South University, Changsha, China
¹²Department of Hematology, Guizhou Provincial People’s Hospital, Guiyang, Guizhou, China, Guiyang, China
¹³National Clinical Research Center for Blood Diseases, State Key Laboratory of Experimental Hematology, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Tianjin, China

Maria Agustina Perusini¹, Claire Andrews, MBBCHBAO^2*, Eshetu G Atenafu, MSc, PStat^3*, Sarit E. Assouline, MD⁴, Joseph Brandwein, MD⁵, Mohammad Jarrar^6*, Steven M. Chan, MD, PhD⁷, Signy Chow, MD, MSc, FRCPC⁸, Dina Khalaf^9*, Vikas Gupta, MD, FRCP, FRCPath¹⁰, Dawn C. Maze, MD, FRCPC, MSc³, Mark D. Minden, MD, PhD^3*, Gizelle Popradi^11*, Waleed Sabry, MD, MSc. PhD, FRCPE^12*, Lalit Saini^13*, David Sanford, MD, FRCPC¹⁴, Lynn Savoie^15*, Aaron Schimmer^3*, Andre C. Schuh, MD, FRCPC³, Karen Yee, MD, FRCPC^3* and Hassan Sibai, MD³

¹Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
²St Vincents Hospital, Dublin, IRL
³Princess Margaret Cancer Centre / University Health Network, Toronto, ON, Canada
⁴Jewish General Hospital, McGill University, Westmount, QC, Canada
⁵Department of Medicine, University of Alberta, Edmonton, AB, Canada
⁶Windsor Regional Hospital, Windsor, Canada
⁷Princess Margaret Cancer Centre, Toronto, ON, Canada
⁸Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
⁹Juravinski Cancer centre, Hamilton, ON, Canada
¹⁰The Princess Margaret Cancer Centre, Toronto, ON, Canada
¹¹McGill University Health Center, Montreal, Canada
¹²Saskatoon Cancer Centre, Saskatoon, SK, Canada
¹³London Health Sciences Centre, London, Canada
¹⁴Department of Medicine, Division of Hematology, University of British Columbia, Leukemia Bone Marrow Transplant Program of British Columbia and Vancouver General Hospital, Vancouver, BC, Canada, Vancouver, Canada
¹⁵University of Calgary, Calgary, Canada

Kai-Wen Tan^1*, Shanshan Pei, PhD^2*, Miao Wang, MD^1*, Lan Dai, MD^1*, Hao Zhang, MD^3*, Chun-Yan Chen, MD^4*, Zhen-Qi Huang, MD^5*, Hai-Ping Dai, MD^1*, Ying Wang^1*, Miao Miao, MD^1*, Yue Han, MD, PhD^6*, Xiaowen Tang^7*, Huiying Qiu, MD, PhD^1*, Suning Chen^1*, Aining Sun, MD, PhD^1*, Depei Wu, MD, PhD¹, Zheng Li, MD^1* and Sheng-Li Xue^1,8*

¹Department of Hematology, The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, Suzhou, China
²Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, hangzhou, China
³Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, China
⁴Department of Hematology, Qilu Hospital of Shandong University, Jinan, China
⁵Department of Hematology, The First Affiliated Hospital of Anhui Medical University, Hefei, China
⁶National Clinical Research Center for Hematologic Diseases, Suzhou, China
⁷National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China
⁸Leukemia Working Group of National Clinical Research Center for Hematologic Diseases, Suzhou, China

Alexandre Iat, MD^1*, Jan Philipp Bewersdorf, MD², Julia Gilhodes^1*, Yiwen Liu, MS^3*, Rory M. Shallis, MD⁴, Leora Boussi, MD⁵, Andrius Zucenka, MD⁶, Rebecca P. Bystrom, MD³, Daniel J. DeAngelo, MD, PhD⁷, Guillaume Berton^8*, Amel Soua^1*, Kelly Ling, PA-C^7*, Luis E. Aguirre, MD⁷, Richard M Stone, MD⁷, Marlise R. Luskin, MD⁷, Jacqueline S. Garcia, MD⁷, Eric S. Winer, MD⁷, Evan C. Chen, MD⁷, Martha Wadleigh, MD⁷, Aaron D. Goldberg⁵, Amer M. Zeidan, MD⁹, Thomas Cluzeau, MD, PhD¹⁰, Shai Shimony, MD⁷, Maximilian Stahl, MD¹¹ and Sylvain Garciaz, MD^12*

¹Institut Paoli-Calmettes, MARSEILLE, France
²Department of Internal Medicine, Section of Hematology, Yale School of Medicine - Yale Cancer Center, New Haven, CT
³Dana-Farber Cancer Institute, Boston, MA
⁴Department of Internal Medicine, Section of Hematology, Yale School of Medicine - Yale Cancer Center, Killingworth, CT
⁵Department of Medicine; Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁶Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania
⁷Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
⁸Hematology Department, Institut Paoli-Calmettes, Marseille, AL, France
⁹Yale School of Medicine, Smilow Cancer Hospital at Yale New Haven, New Haven, CT
¹⁰Department for Clinical Hematology, Nice University Hospital, Nice, Provence Alpes Cote d'Azur, France
¹¹Dana Farber Cancer Institute, Boston, MA
¹²Aix-Marseille University, INSERM U1068, CNRS, Institut Paoli-Calmettes, CRCM, Marseille, France

Nishan Shaik, MPH^1*, Harry P. Erba, MD, PhD², Sudhir Unni^3*, Svenja Petersohn^4*, Elizabeth Westerberg, PhD^5*, Boris Gorsh, PharmD^6*, Akash Nahar, MD^7*, Kristy Burns, PhD^7* and Sonja Kroep^5*

¹OPEN Health, Thiruvananthapuram, AL, India
²Duke University Cancer Institute, Durham, NC
³Daiichi Sankyo, Inc, Basking Ridge, NJ
⁴OPEN Health, Antwerp, Belgium
⁵OPEN Health, Rotterdam, Netherlands
⁶Daiichi Sankyo Inc, New Jersey, NJ
⁷Daiichi Sankyo, Inc., Basking Ridge, NJ

Stephen Lam, PhD, MBBS,^1*, Li-Chuan Zheng^1*, Kelvin K.W. Wong^2*, Man Kit Garret Leung^1*, Chenqinyao Li^1*, Kwui-Wa Tong^1,3*, Wing Lam^4*, Xiao-yuan Zheng^1*, Koon C. Chan^1,3*, Natalie Nok-Man Chan^1,3*, Ka Lam Nelson K. L. Ng, PhD^1,5*, Chee Chean Dang^1*, Tsz-Ho Kwok^1*, Sze Pui Tsui, MSc^1,6*, Rakesh Sharma^2*, Jason W.H. Wong^7*, Suet Yi Leung, MD, PhD^3,6,8*, Cheuk-Him Man, PhD^1,9* and Anskar Y.H. Leung, MD, PhD^1,3,8

¹Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
²Proteomics and Metabolomics Core, Centre for PanorOmic Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
³Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong, China
⁴Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong
⁵Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong, Hong Kong
⁶Department of Pathology, Queen Mary Hospital, Hong Kong, China
⁷School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
⁸The Jockey Club Centre for Clinical Innovation and Discovery, The University of Hong Kong, Hong Kong, China
⁹Key Laboratory of Stem Cells and Tissue Engineering (Ministry of Education), Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

Emmanuel Almanza, MD^1*, Wei-Ying Jen, MD, FRCPath, MA^1*, Courtney D. DiNardo, MD, MSc², Kelly S. Chien, MD³, Danielle Hammond, MD¹, Yesid Alvarado Valero, MD¹, Naveen Pemmaraju, MD⁴, Lucia Masarova, MD¹, Sherry Pierce, BSN, BA^1*, Naval Daver, MD⁵, Alex Bataller, MD, PhD^1*, Guillermo Garcia-Manero, MD¹, Amin M. Alousi, MD^6*, Nicholas J. Short, MD¹, Farhad Ravandi, MBBS⁷, Hagop M. Kantarjian, MD¹ and Tapan M. Kadia, MD¹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
³Department of Leukemia, MD Anderson, Houston, TX
⁴Department of Leukemia, The University of Texas MD Anderson Cancer Center, Bellaire, TX
⁵MD Anderson Cancer Center, Houston, TX
⁶Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX

Pau Montesinos, PhD, MD^1*, Rebeca Rodriguez-Veiga, MD, PhD^1*, Juan Miguel Bergua Burgues, MD^2*, Jesús Lorenzo Algarra, MD^3*, Carmen Botella^4*, Eduardo Rodriguez Arboli, MD MPhil^5*, Teresa Bernal Del Castillo, MD, PhD^6*, Mar Tormo, MD⁷, Maria Calbacho, MD^8*, Olga Salamero, MD^9*, Josefina Serrano, MD^10*, Victor Noriega Concepcion, MD^11*, Juan Antonio Lopez Lopez^12*, Susana Vives, MD^13*, Jose Luis Lopez Lorenzo, MD^14*, Mercedes Colorado, PhD^15*, Maria Vidriales Vicente^16*, Raimundo Garcia Boyero, MD^17*, Maria Teresa Olave Rubio^18*, Pilar Herrera^19*, Olga Arce, MD^20*, Manuel Barrios Garcia^21*, Maria Jose Sayas Lloris, MD^22*, Marta Polo, MD^23*, Maria Isabel Gómez Roncero, MD^24*, Eva Barragán, PhD^25*, Rosa Ayala, MD^26*, Carmen Chillon, MD^27*, Maria Jose Calasanz, PhD^28*, Bruno Paiva, PhD^29*, Blanca Boluda^25*, Ignacio Casas Aviles, M.D^2*, Pilar Lloret Madrid, MD^30*, María-José Sánchez-Sánchez^31*, Carlos Rodríguez-Medina, MD, PhD^32*, Laida Cuevas Palomares^33*, Jose Ángel Raposo Puglia^34*, M Carmen Mateos Rodríguez^35*, Matxalen Olivares Salaverri^36*, Maria Del Carmen Martinez Chamorro^37*, Natalia Alonso Vence^38*, Sandra Suarez Ordoñez, MD^39*, Irene Sanchez Vadillo^40*, María Solé-Rodríguez^41*, Bernardo Javier González González, MD^42*, Antonio Martinez Frances^43*, Rebeca Cuello^44*, Alfonso Fernández Fernández, MD^45*, David Martinez-Cuadron, PhD²⁵ and Jorge Labrador, MD^46*

¹Department of Hematology, Hospital Universitari i Politècnic La Fe, Valencia, Spain
²Hospital San Pedro de Alcántara, Caceres, Spain
³Hospital General de Albacete, Albacete, Spain
⁴Hospital General Universitario de Alicante, Alicante, Spain
⁵University Hospital Virgen del Rocío, Seville, Spain
⁶Hospital Universitario Central de Asturias, Oviedo, Spain
⁷INCLIVA Research Institute, University Clinical Hospital, Valencia, Spain
⁸Hematology Department, Hospital Universitario 12 de Octubre, Madrid, Madrid, Spain
⁹Department of Hematology, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain
¹⁰Department of Hematology, Hospital Universitario Reina Sofía, IMIBIC.UCO, Cordoba, ESP
¹¹Hospital Universitario de A Coruña, A Coruña, ESP
¹²Hospital Universitario de Jaen, Jaen, Spain
¹³Hospital Germans Trias i Pujol, Badalona, ESP
¹⁴Fundacion Jimenez Diaz, Madrid, ESP
¹⁵Hospital Marqués De Valdecilla, Santander, Cantabria, ESP
¹⁶Hospital Universitario de Salamanca, Salamanca, Spain
¹⁷Hospital General Universitario de Castellon, Castellon, Spain
¹⁸Hospital Clinico Universitario Lorenzo Blesa, Zaragoza, ESP
¹⁹Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain
²⁰Hospital Universitario de Basurto, Bilbao, Spain
²¹Hospital Universitario Regional de Malaga, Malaga, Spain
²²Hospital Dr. Peset, Valencia, Spain
²³Hospital Clínico San Carlos, MADRID, ESP
²⁴Hospital Virgen de la Salud, Toledo, Spain
²⁵Hospital Universitary i Politecnic La Fe, Valencia, Spain
²⁶Department of Hematology, Hospital Universitario 12 de Octubre, Spanish National Cancer Research Center (CNIO), Complutense University Madrid, Madrid, Spain
²⁷Haematology Department, University Hospital of Salamanca, Research Biomedical Institute of Salamanca (IBSAL), CIBERONC and Center for Cancer Research-IBMCC (USAL-CSIC), Salamanca, Spain
²⁸CIMA LAB Diagnostics, Universidad de Navarra, Pamplona, Spain
²⁹Department of Hematology, Centre for Applied Medical Research, Cancer Center Clinica Universidad de Navarra, University of Navarra, IdiSNA, CIBERONC, Pamplona, Spain
³⁰Hospital Universitari I Politécnic La Fe, Valencia, ESP
³¹Hospital Lucus Augusti, Lugo, ESP
³²Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas, ESP
³³Hospital Universitario De Alava, Vitoria, Spain
³⁴Hospital Universitario Puerta del Mar, Cádiz, Spain
³⁵Hospital Universitario de Navarra, Pamplona, ESP
³⁶Hospital Galdakao-Usansolo Ospitalea, Bizkaia, Spain
³⁷University Hospital Quirónsalud, Pozuelo de Alarcón, Madrid, Spain
³⁸University Hospital of Santiago de Compostela, Department of Hematology, IDIS, Santiago de Compostela, Spain
³⁹Hematology Department, Complejo Hospitalario de Vigo, Vigo, Spain
⁴⁰Hospital Universitario La Paz, Madrid, ESP
⁴¹Hospital Universitario Juan Ramón Jiménez, Huelva, ESP
⁴²Hospital Universitario de Canarias, Tenerife, Spain
⁴³Hospital General Universitario Santa Lucía, Cartagena, ESP
⁴⁴Hospital Clínico Universitario de Valladolid, Valladolid, Spain
⁴⁵Hospital Universitario Virgen de la Victoria, Málaga, CA, ESP
⁴⁶Department of Hematology, Hospital Universitario de Burgos, Universidad Isabel I, Burgos, Spain

Jayastu Senapati, MD, DM, MBBS¹, Hagop M. Kantarjian, MD¹, Edward Ayoub, PhD^2*, Akhil Jain, MD^1*, Tapan M. Kadia, MD¹, Courtney D. DiNardo, MD, MSc³, Naval Daver, MD⁴, Fadi G. Haddad, MD¹, Naveen Pemmaraju, MD⁵, Nicholas J. Short, MD¹, Maro Ohanian, DO^1*, Musa Yilmaz, MD^1*, Keyur P. Patel, MD, PhD^6*, Mark Brandt, BS^7*, Sherry Pierce, BSN, BA^1*, Guillermo Garcia-Manero, MD¹, Farhad Ravandi, MBBS⁸ and Gautam Borthakur, MD²

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
⁴MD Anderson Cancer Center, Houston, TX
⁵Department of Leukemia, The University of Texas MD Anderson Cancer Center, Bellaire, TX
⁶Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷The University of Texas MD Anderson Cancer Center, Houston, TX
⁸Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX

Eunice S. Wang, MD¹, Jorge E. Cortes, MD², Justin M. Watts, MD³, Brian A. Jonas, MD, PhD⁴, Andrew H Wei, MBBS, PhD, FRACP, FRCPA⁵, Jay Yang, MD⁶, Joseph G Jurcic, MD⁷, Gail J. Roboz, MD⁸, Karen Seiter, MD⁹, Alice Mims, MD¹⁰, Karen Yee, MD, FRCPC^11*, P. Brent Ferrell, MD¹², Shira N. Dinner, MD¹³, William B. Donnellan, MD¹⁴, William Blum, MD¹⁵, Francois Di Trapani^16*, Hua Tian^16* and Stephane De Botton, MD, PhD^17*

¹Leukemia Service, Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY
²Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA
³Sylvester Cancer Center, University of Miami Miller School of Medicine, Miami, FL
⁴Department of Internal Medicine, Division of Malignant Hematology/Cellular Therapy and Transplantation, University of California Davis School of Medicine, Sacramento, CA
⁵Department of Haematology, The Alfred Hospital, Melbourne, VIC, Australia
⁶Department of Oncology, Karmanos Cancer Institute/Wayne State University, Detroit, MI
⁷Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY
⁸Weill Cornell Medicine and The New York Presbyterian Hospital in New York City, New York, NY
⁹New York Medical College, Valhalla, NY
¹⁰The Ohio State University Comprehensive Cancer Center, Columbus, OH
¹¹Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada
¹²Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN
¹³Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL
¹⁴Sarah Cannon Research Institute, Tennessee Oncology, Nashville, TN
¹⁵Emory University, Winship Cancer Institute, Atlanta, GA
¹⁶Rigel Pharmaceuticals, Inc., South San Francisco, CA
¹⁷Department of Hematology, Institut Gustave Roussy, Villejuif, France

Marina Konopleva¹, Naveen Pemmaraju, MD², Kendra L. Sweet, MD³, Anthony S. Stein, MD⁴, David A. Rizzieri, MD^5*, Eunice S. Wang, MD⁶, Sumithira Vasu, MD, MBBS⁷, Todd Rosenblat, MD, MS^8*, Michael Zuurman, PhD^9*, Ira Gupta, MD¹⁰ and Andrew A. Lane, MD, PhD¹¹

¹Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, NY
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Bellaire, TX
³Moffitt Cancer Center, Tampa, FL
⁴Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA
⁵Novant Health Cancer Institute, Winston Salem, NC
⁶Roswell Park Comprehensive Cancer Center, Buffalo, NY
⁷The Ohio State University Comprehensive Cancer Center, Columbus, OH
⁸Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY
⁹Menarini Group, Machelen, Belgium
¹⁰Menarini Group, New York, NY
¹¹Adult Leukemia Program, Dana-Farber Cancer Institute, Boston, MA

Guopan Yu, MD, PhD^1*, Yishan Chen^1*, Zhao Yin^1*, Yu Zhang^1*, Weihua Zhao, MD^2*, Guangyang Weng, MD^3*, Xin Du^3*, Danian Nie, MD^4*, Ziwen Guo^5*, Zhiqiang Sun, MD, PhD^6*, Hongyu Zhang⁷, Dongjun Lin^8*, Xinquan Liang^9*, Pengcheng Shi^1*, Xuejie Jiang, M.D.^10*, Dan Xu^1*, Li Xuan^1*, Baohong Ping^1* and Qifa Liu, MD¹

¹Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China
²Department of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Nanning, China
³Department of Hematology, Shenzhen Second People's Hospital, Shenzhen, China
⁴Department of Hematology, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, China
⁵Department of Hematology, Zhongshan City People’s Hospital, Zhongshan, China
⁶Department of Hematology, Shenzhen Hospital, Southern Medical University, Shenzhen, China
⁷Department of Hematology, Peking University Shenzhen Hospital, Shenzhen, China
⁸Department of Hematology, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, China
⁹First People's Hospitalof Chenzhou, Chenzhou, China
¹⁰Department of Hematology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China

Benjamin J. Lee, PharmD^1,2*, Shawn P. Griffin, PharmD^3,4*, Jean Doh, PharmD^3*, Stefan O. Ciurea, MD⁵, Piyanuch Kongtim, MD^5*, Deepa Jeyakumar, MD⁶ and Kiran Naqvi, MD, MPH⁷

¹Department of Pharmacy, University of California Irvine Health, Orange, CA
²Department of Clinical Pharmacy Practice, University of California Irvine, School of Pharmacy & Pharmaceutical Sciences, Irvine, CA
³Department of Clinical Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, University of California Irvine, Irvine, CA
⁴Department of Pharmacy, University of California Irvine, Orange, CA
⁵Hematopoietic Stem Cell Transplantation and Cellular Therapy Program, Division of Hematology/Oncology, Department of Medicine, University of California Irvine, Orange, CA
⁶Department of Medicine, Division of Hematology Oncology, Chao Family Comprehensive Cancer Center, University of California Irvine Health, University of California Irvine, Orange, CA
⁷Department of Medicine, Division of Hematology Oncology, Chao Family Comprehensive Cancer Center,, University of California Irvine Health, Orange, California, USA, Orange, CA

Emmanuelle Tavernier, MD^1*, Jérôme Cornillon^1*, Zofia Gross, MD^2*, Gaspar Aspas Requena^3*, Urbain Tauveron-Jalenques^3*, Martin Carré, MD^4*, Mathieu Meunier^5*, Ugo Thévenet, MD^1*, Boullanger Fow Heng Nadine^6*, Clémence Santana^7*, Clément Rocher, MD^8*, Sylvain Lamure, MD, PhD^9*, Amine Belhabri, MD^10*, Mauricette Michallet, MD, PhD¹⁰, Adrien Contejean^11*, Natacha Mauz^11*, Gian Matteo Pica, MD^12*, Arthur Dony^12* and Mael Heiblig^2*

¹Département d'hématologie Clinique et de Thérapie Cellulaire, CHU Saint-Etienne, Saint-Etienne, France
²Département d'Hématologie, CHU de Lyon, Pierre-Bénite, France
³Département d'Hématologie, CHU de Clermont-Ferrand, Clermont-Ferrand, France
⁴Département d'Hématologie, CHU de Grenoble Alpes, Grenoble, France
⁵Department of Hematology CHU Grenoble Alpes, Grenoble, France
⁶Département d'Onco-Hématologie, CH de Roanne, Roanne, France
⁷Département d'Hématologie, CH de Valence, Valence, France
⁸Département d'Hématologie, Centre Hospitalier Bourgoin Jallieu, Bourgoin Jallieu, France
⁹Département d'Onco-Hématologie, Hôpitaux Nord-Ouest, Villefranche-sur-Saone, France
¹⁰Département de Cancérologie médicale, Centre Léon Bérard, Lyon, France
¹¹Département d'Hématologie, Centre Hospitalier Annecy Genevois, Epagny Metz-Tessy, France
¹²Département d'Hématologie, CH Chambery, Chambéry, France

Xiawei Zhang^1,2*, Jingjing Yang^1,2*, Sai Huang^3*, Qingyang Liu^1,4*, Liping Dou, MD⁵, Chunji Gao, MD^1* and Daihong Liu, MD^5*

¹The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China
²Medical School of Chinese PLA, Beijing, China
³Department of Hematology, Chinese PLA General Hospita, Beijing, China
⁴Chinese People's Liberation Army(PLA) Medical School, Beijing, China
⁵Department of Hematology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China

Onyee Chan, MD¹, Kendra L. Sweet, MD¹, Jhada-Kai Hunter^1*, Somedeb Ball, MD², Qianxing Mo, PhD^3*, Zhuoer Xie, MD, MS¹, Seongseok Yun, MD, PhD¹, Andrew T. Kuykendall, MD¹, Eric Padron, MD¹, Alison R. Walker, MD, MBA, MPH¹, Rami S. Komrokji, MD¹, Jeffrey E Lancet, MD¹ and David Sallman, MD⁴

¹Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
²Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN
³Moffitt Cancer Center, Tampa, FL
⁴Moffitt Cancer Center and Research Institute, Tampa, FL

Shaolei Zang^*, Min Ji, MD, PhD^*, Jingru Zhang^*, Fei Lu^*, Chunqing Zhang^*, Jingjing Ye^* and Chunyan Ji

Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China

Asad Bashey, MD, PhD¹, Xu Zhang, PhD^2*, Lawrence E Morris, MD³, H. Kent Holland, MD^1*, Lizamarie Bachier-Rodriguez^1*, Scott R. Solomon, MD³ and Melhem M. Solh, MD³

¹BMT Program at Northside Hospital, Atlanta, GA
²Center for Clinical and Transitional Sciences,, University of Texas, Houston, TX
³Blood and Marrow Transplant Group of Georgia, Atlanta, GA

Francesco Angotzi^1*, Erika Borlenghi, MD^2*, Chiara Sartor, MD^3*, Maria Benedetta Giannini, MD^4*, Giovanni Marconi, MD⁴, Edoardo Tamellini, MD^5*, Mauro Turrini, MD^6*, Federica Loscocco, MD^7*, Ernesta Audisio, MD^8*, Vincenzo Federico, MD^9*, Calogero Vetro, MD^10*, Andrea Visentin, MD, PhD^11*, Carmela Gurrieri, MD^1*, Livio Trentin¹², Felicetto Ferrara, MD^13* and Federica Lessi^12*

¹Hematology Unit, Department of Medicine, University of Padova, Padova, Italy
²ASST Spedali Civili, Brescia, Department of Hematology, Brescia, Italy
³Istituto di Ematologia “Seràgnoli”, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
⁴Hematology Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori “Dino Amadori”, Meldola, Meldola, Italy
⁵Hematology Unit, Department of Engineering and Innovation Medicine, University of Verona, Verona, Verona, Italy
⁶Hematology Unit, Division of Hematology, Valduce Hospital, Como, Como, Italy
⁷Hematology and Stem Cell Transplant Center, AST 1, Pesaro, Pesaro, Italy
⁸Department of Oncology, Division of Hematology, AOU City of Health and Science of Turin, Turin, Turin, Italy
⁹Hematology and Stem Cell Transplant Unit, Presidio Ospedaliero “Vito Fazzi”, Lecce, Lecce, Italy
¹⁰Hematology and BMT Unit, Azienda Ospedaliero Universitaria Policlinico “G. Rodolico-San Marco”, Catania, Catania, Italy
¹¹Hematology unit, Department of Medicine, University of Padova, Padova, Padova, Italy
¹²Hematology Unit, Department of Medicine, University of Padova, Padova, Padova, Italy
¹³Division of Hematology, AORN Cardarelli, Naples, Napoli, Italy

Marcelo Pitombeira de Lacerda, MD, PhD^1,2*, Elenaide Nunes, MD^3*, Giovanna Steffenello, MD, MSc^4*, Thiago Xavier Carneiro, MD, PhD^5*, Ivan Schneider Boettcher, MD^1*, Ana Claudia Dall'Oglio, MD^1*, Fernanda Martini, MD^1*, Leonardo Esmeraldino, MD^1*, Mayara Molossi, MD^1*, Andressa Oliveira Martin Wagner^6*, Ederson Roberto Mattos, MD^7* and Celso Arrais-Rodrigues, MD, PhD^8,9

¹Hospital Municipal Sao Jose, Joinville, Brazil
²Universidade da Região de Joinville (Univille), Joinville, Santa Catarina, Brazil
³Hospital de Clínicas da Universidade Federal do Paraná, Curitiba, Brazil
⁴UFSC, Hospital Universitario Polydoro Ernani de Sao Thiago, Florianopolis, BRA
⁵Hospital Ophir Loyola, Belem, BRA
⁶UFSC, Hospital Universitario Polydoro Ernani de São Thiago, Florianopolis, Brazil
⁷Hospital Amaral Carvalho, Jau, BRA
⁸Division of Hematology - UNIFESP, São Paulo, Brazil
⁹Hospital Nove de Julho - DASA, São Paulo, Brazil

Catherine E. Lai, MD¹, Thomas P. Leahy, PhD^2*, Alex Turner, PhD^3*, Amber Thomassen, ANP, MA, MSN^4*, Lixia Wang, PhD^4*, Aaron Sheppard, PhD^4* and Jorge E. Cortes, MD⁵

¹Division of Hematology and Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
²Putnam Associates, Toronto, ON, Canada
³Putnam Associates, London, United Kingdom
⁴Rigel Pharmaceuticals, Inc., South San Francisco, CA
⁵Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA

Yinjun Lou, MD, PhD^1,2*, Jie Jin, M.D.^2,3, Hongyan Tong, PhD^1,3, Shanshan Suo, MD^4*, Huafeng Wang^1,5*, Liping Mao, M.D.^5*, Haitao Meng^6* and Wenjuan Yu^7*

¹Zhejiang Provincial Key Lab of Hematopoietic Malignancy, Zhejiang University, Hangzhou, China
²Department of Hematology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Hangzhou, China
³Department of Hematology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
⁴Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, PR China;, Hangzhou, China
⁵Department of Hematology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⁶Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⁷Zhejiang Provincial Key Laboratory of Hematopoietic Malignancy, Zhejiang University, Hangzhou, China

Chao-Ling Wan^1*, Yu-Qing Liu^2*, Fang-Tong Liu^1*, Yuan-Hong Huang^1*, Han-Yu Cao^1*, Si-Man Huang^1*, Kai-Wen Tan^1*, Zihao Wang^1*, Shuai-Shuai Ge^1*, Miao Wang, MD^1*, Haiping Dai^3* and Sheng-Li Xue^1*

¹Department of Hematology, The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, Suzhou, China
²Changshu Hospital Affiliated to Soochow University, Changshu No.1 People's Hospital, Changshu, Jiangsu Province, China
³The first Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, National Clinical Research Center of Hematologic Diseases, Suzhou, China

Lydia Kretschmer, MD^1*, Leo Ruhnke, MD^2*, Christoph Schliemann, MD^3*, Lars Fransecky, MD^4*, Björn Steffen, MD^5*, Martin Kaufmann, MD⁶, Andreas Burchert, MD⁷, Christoph Schmid, MD^8*, Maher Hanoun, MD, PhD^9*, Tim Sauer, MD¹⁰, Klaus H Metzeler, MD¹¹, Kerstin Schäfer-Eckart, MD^12*, Mathias Hänel, MD¹³, Martina Crysandt, MD^14*, Paul Jäger^15*, Stefan W. Krause, MD^16*, Christine Dierks^17*, Stefan Klein, MD¹⁸, Nadia Maguire^19*, Lukas Peter Frenzel^20*, Veit L. Buecklein, MD^21*, Frank Fiebig^2*, Anna Harig^1*, Christian Thiede^22,23*, Moritz Middeke, MD^24*, Richard Dillon, MA²⁵, Claudia D Baldus, MD^26*, Hubert Serve, MD²⁷, Uwe Platzbecker, MD¹¹, Karsten Spiekermann, MD^28*, Wolfgang Hiddemann, MD^29*, Martin Bornhäuser, MD^30*, Richard F. Schlenk, MD^10*, Carsten Müller-Tidow, MD^10* and Christoph Röllig, MD^31*

¹University Hospital Dresden, Dresden, Germany
²Department of Internal Medicine I, University Hospital Dresden, Dresden, Germany
³Department of Medicine A, University Hospital Muenster, Muenster, Germany
⁴Department of Internal Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany
⁵Department of Medicine, Hematology/Oncology, Goethe University Frankfurt, University Hospital, Frankfurt, Germany
⁶Department of Hematology, Oncology and Palliative Care, Robert Bosch Hospital, Stuttgart, Germany
⁷Department of Hematology, Oncology and Immunology, University Hospital Marburg, Marburg, Germany
⁸Department of Hematology, University Hospital Augsburg, Augsburg, Germany
⁹Department of Hematology and Stem Cell Transplantation, University Hospital Essen, Essen, Germany
¹⁰Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany
¹¹Department for Hematology, Cell Therapy, Hemostaseology and Infectious Diseases, University of Leipzig Medical Center, Leipzig, Germany
¹²Department of Internal Medicine V, Paracelsus University Hospital Nuremberg, Nuremberg, Germany
¹³Department of Internal Medicine III, Klinikum Chemnitz, Chemnitz, Germany
¹⁴University Hospital RWTH Aachen, Aachen, DEU
¹⁵University of Duesseldorf, Duesseldorf, DEU
¹⁶Universitätsklinikum Erlangen, Erlangen, Germany
¹⁷Hematology/Oncology and Stemcell Transplantation, University of Halle-Wittenberg, Halle, Germany
¹⁸Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany
¹⁹Krankenhaus Barmherzige Brüder, Regensburg, Germany
²⁰Center of Integrated Oncology Aachen Bonn Cologne Duesseldorf (ABCD), University Hospital Cologne, Cologne, Germany
²¹Department of Medicine III, LMU University Hospital, Munich, Germany
²²University Hospital Carl Gustav Carus TU Dresden, Dresden, Germany
²³AgenDix GmbH, Dresden, Germany
²⁴Department of Internal Medicine 1, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany
²⁵King’s College London, London, United Kingdom
²⁶Department of Internal Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein, Kiel, Germany
²⁷Department of Medicine, Hematology/Oncology, Goethe-University Frankfurt, University Hospital, Frankfurt am Main, Germany
²⁸Department of Medicine III, University Hospital, LMU Munich, Munich, Germany
²⁹Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany
³⁰National Center for Tumor Diseases (NCT/UCC) Dresden, Technical University Dresden, Dresden, Germany
³¹Department of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Saxony, Germany

Courtney D. DiNardo, MD, MSc¹, Kelly S. Chien, MD², Jillian Mullin, BA, RN, MN^2*, Danielle Hammond, MD², Jeremy Ramdial, MD³, Tapan M. Kadia, MD², Fadi G. Haddad, MD², Musa Yilmaz, MD^2*, Koji Sasaki, MD², Ghayas C. Issa, MD², Koichi Takahashi, MD, PhD², Elizabeth J. Shpall, MD³, Farhad Ravandi, MBBS⁴, Naval Daver, MD⁵ and Hagop Kantarjian, MD²

¹Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX
⁵MD Anderson Cancer Center, Houston, TX