-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

605.P1.54 605. Molecular Pharmacology and Drug Resistance: Lymphoid Neoplasms: Poster I

Symposia: Molecular Pharmacology and Drug Resistance: Lymphoid Neoplasms Program: Oral and Poster Abstracts
Type: Poster
Saturday, December 7, 2024: 5:30 PM-7:30 PM
Halls G-H (San Diego Convention Center)

Rudra Prasad Dutta1*, Heng-Huan Lee, Ph.D2*, Ravi Prakash Shukla, Ph.D1*, Violetta V Leshchenko, Ph.D1*, Fanye Meng, Ph.D3*, Fangfang Yan, Ph.D2*, Yang Liu, Ph.D2*, Husnu Kaniskan, Ph.D3*, Jian Jin, Ph.D3*, Lapo Alinari, MD, Ph.D4, Michael Wang, MD2 and Samir Parekh, MD1

1Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, Tisch Cancer Institute, New York, NY
2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
3Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, Mount Sinai Center for Therapeutics Discovery, Tisch Cancer Institute, New York, NY
4Department of Internal Medicine, Division of Hematology, The Ohio State University, Columbus, OH

Betsy A Pray, MSc, DVM, BS1, Ethan Baiocchi2*, Sydney Leon2*, Brian Barta2*, Shirsha Koirala2*, Wing Chan, PhD2, Walter Hanel, MD, PhD3, Lalit Sehgal, PhD2, Robert Baiocchi, MD, PhD2 and Lapo Alinari, MD, Ph.D2

1College of Veterinary Medicine, The Ohio State University, WESTERVILLE, OH
2James Comprehensive Cancer Center, The Ohio State University, Columbus, OH
3James Comprehensive Cancer Center, The Ohio State University, Dublin, OH

Dengchao Cao, PhD1*, Mianmian Yin, PhD1*, Timour Baslan, PhD2*, Ryan Bertoli, BS1*, Zhenhua Zhang, MS1*, Yuelin Zhu, PhD1*, Paul S. Meltzer, MD, PhD1* and Peter D. Aplan, MD1

1Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
2Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY

Aki Tanabe, MD, PhD1*, Yoshiaki Takahashi2*, Anna Yui3*, Makoto Nakakido3*, Tomohiro Nasu4*, Mami Uemura5*, Kenta Tezuka5*, Kaoru Uchimaru, MD, PhD4*, Atae Utsunomiya, MD, PhD6, Tetsuro Matano7*, Takuo Mizukami5*, Toshiki Watanabe8*, Kouhei Tsumoto3,9,10* and Kazumi Nakano5*

1AIDS research center, National Institute of Infectious Diseases, Shinjuku, TKY, Japan
2Department of Investigative Medicine, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan
3Department of Bioengineering, School of Engineering, The University of Tokyo, Tokyo, Japan
4Laboratory of Tumor Cell Biology, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan
5Research Center for Biological Products in the Next Generation, National Institute of Infectious Diseases, Tokyo, Japan
6Department of Hematology, Imamura General Hospital, Kagoshima, Japan
7AIDS research center, National Institute of Infectious Diseases, Tokyo, Japan
8Department of Hematology/Oncology, St. Marianna University School of Medicine, Kanagawa, Japan
9Department of chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo, Japan
10The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

Samuel J. Holzmayer1,2*, Jonas Mauermann1,2*, Sarah M. Greiner1,2,3*, Jonas S. Heitmann, MD1,2*, Kübra Kaban1,2*, Helmut R. Salih, MD1,2* and Melanie Maerklin1,2*

1DFG Cluster of Excellence 2180 ‘Image-guided and Functional Instructed Tumor Therapy’ (IFIT), University of Tübingen, Tübingen, Germany
2Clinical Collaboration Unit Translational Immunology, German Cancer Consortium (DKTK), Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany
3Department of Obstetrics and Gynecology, University Hospital Tübingen, Tübingen, Germany

Peter Gordon, MD/PhD1,2,3, Robin Williams, MD, MS4, Jason Ostergaard, BS5*, Joseph Muretta, PhD6*, Bridget S. Wilson, PhD7*, Luke Lambert, MS8*, Timothy P. Singleton, MD9, Sarah K Tasian, MD10 and Stuart S. Winter, MD11,12

1Pediatric Hematology/Oncology, Umn Center For Allied Health Programs, Saint Paul, MN
2Masonic Cancer Center, University of Minnesota, Minneapolis, MN
3Umn Center For Allied Health Programs, Minneapolis, MN
4University of Minnesota Masonic Children’s Hospital, Saint Paul, MN
5Pediatric Hematology/Oncology, University of Minnesota, Minneapolis, MN
6College of Biological Sciences, University of Minnesota, Minneapolis, MN
7Pathology, University of New Mexico, Albuquerque, NM
8Children's Minnesota, Minnesota, MN
9Children's Minnesota, Edina, MN
10Division of Oncology & Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA
11Cancer and Blood Disorders, Children's Minnesota, Eagan, MN
12Cancer and Blood Disorders, Children's Minnesota, Minneapolis, MN

Lorena Fontan, PhD1, Adam Zwolak2*, Irene Guimerans-Lorenzo1*, Mariette Bekkers1*, Nicholas Hein2*, Nele Vloemans1*, Emanuele Trella1*, Tina Smets1*, Ivo Cornelissen1*, Alemu Assefa1*, Bie Verbist, PhD1*, Ricardo Amorim, PhD1*, Pankaj Seth, PhD2*, Ranjeet Prasad Dash2*, Leopoldo Luistro, PhD2*, Bethany Mattson, PhD2*, Matthew A. Dragovich3*, Michael Hedvat3*, Gregory L. Moore3*, John R. Desjarlais, PhD3*, Olivia Kutlu4*, Joseph Erhardt2* and Ulrike Philippar, PhD1

1Janssen Research & Development, Beerse, Belgium
2Janssen Research & Development, Spring House, PA
3Xencor, Inc., Pasadena, CA
4Janssen Research & Development, Los Angeles, CA

Junfei Zhao1*, Marta Larrayoz, PhD2*, Chad C. Bjorklund1*, Anita K. Gandhi, PhD3, Jose A. Martinez-Climent, MD, PhD4, Patrick R. Hagner, PhD1* and Maria Ortiz5*

1Bristol Myers Squibb, Summit, NJ
2Hematology and Oncology Program, Centre for Applied Medical Research (CIMA), Instituto de Investigaciones Sanitarias de Navarra (IdiSNA), Cancer Center Clinica Universidad de Navarra (CCUN), Pamplona, Spain
3Translational Medicine, Bristol Myers Squibb, Summit, NJ
4Department of Hematology, Centre for Applied Medical Research, Cancer Center Clinica Universidad de Navarra, University of Navarra, IdiSNA, CIBERONC, Pamplona, Spain
5Bristol Myers Squibb, Seville, Spain

Shiyi Xie1*, Zhen Yu2,3*, Mu Hao, MD3*, Lu-Gui Qiu3, Mariateresa Fulciniti, PhD4, Nikhil C. Munshi, MD5 and Yan Xu, MD6,7*

1Chinese Academy of Medical Sciences and Peking Union Medical College, National Clinical Research Center for Blood Diseases, State Key Laboratory of Experimental Hematology, Tianjin, China
2State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, CHN
3State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology& Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
4Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
5Dana-Farber Cancer Institute, Boston, MA
6Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China
7State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Boston, MA

Daisy V. Tran1*, Evelyn Teh, PhD2*, Susanne Penny, PhD2*, Devanand M. Pinto, PhD2*, Samuel D. Saibil, MD, PhD1*, John Kuruvilla, MD, FRCPC1 and Rob C. Laister, PhD1

1Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON, Canada
2Human Health Therapeutics, National Research Council, Halifax, NS, Canada

Kadriye Nehir Cosgun, PhD1*, Mark E Robinson, PhD1*, Nikol Agadzhanian, MSc1*, Philipp Berning, MD1*, David Fonseca-Arce1*, Etienne Leveille, MD1*, Shalin Kothari, MD1*, Matthew S. Davids, MD, MMSc2, Julia Jellusova, PhD3* and Markus Müschen, MD1

1Center of Molecular and Cellular Oncology, Yale University, New Haven, CT
2Department of Medical Oncology, Dana-Farber Cancer Institute, Inc., Boston, MA
3School of Medicine and Health, TranslaTUM, Institute of Clinical Chemistry and Pathobiochemistry, Munich, Germany

Caiqin Wang1*, Yizi He1*, Yajun Li, MD2*, Ruolan Zeng1*, Zhiming Li, PhD, MD3, Ling Xiao4* and Hui Zhou, PhD1

1Department of Lymphoma and Hematology, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, Changsha, China
2Hunan Cancer Hospital, Changsha, China
3Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, China
4Department of Histology and Embryology of School of Basic Medical Science, Central South University, Changsha, China

Mahipal Gurram Sinnollareddy, PhD1*, Leonid Gibiansky, PhD2*, Kinjal Sanghavi, PhD3*, Steven Xu, PhD4*, Mohamed-Eslam F Mohamed, PhD1*, Poliana P. Patah1, Elena Favaro, MD, PhD5*, Manish Gupta, PhD4*, Apurvasena Parikh, PhD6* and Tommy Li, PhD4*

1AbbVie, North Chicago, IL
2QuantPharm LLC, North Potomac, MD
3Genmab, Plainsboro, NJ
4Genmab, Princeton, NJ
5Genmab, Copenhagen, Denmark
6AbbVie Inc., South San Francisco, CA

Zhiyan Liang, PhD1*, Yan Yin, MS2*, Huanshan Guo, MD3*, Baisong Li, MS2*, Dajun Yang, MD, PhD1,2,4* and Yifan Zhai, MD, PhD1,2,3

1Ascentage Pharma Group Inc., Rockville, MD
2Ascentage Pharma (Suzhou) Co., Ltd., Suzhou, China
3Guangzhou Healthquest Pharma Co., Ltd., Guangzhou, China
4Department of Experimental Research, State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China

Edward Chow1*, Rui Xue Lee2*, Jhin Jieh Lim1* and Masturah Rashid1*

1KYAN Technologies, Singapore, Singapore
2National University of Singapore, Singapore, Singapore

Calvin Lam1, Yiqian Wang, BS2*, Victor Rivero1*, Jogdeo Chinmay, PhD3*, Ekta Kapoor, PhD3*, Siyuan Tang, PhD3*, Peng Xiao, PhD4*, Svetlana Romanova, PhD3*, David Oupicky, PhD3* and Kate Hyde, PhD5,6

1Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE
2University of Nebraska Medical Center, Omaha, NE
3Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE
4Department of Genetics, Cell Biology, and Anatomy, and UNMC Bioinformatics and Systems Biology Core, University of Nebraska Medical Center, Omaha, NE
5Department of Biochemistry and Molecular Biology, and Fred and Pamela Buffet Cancer Center, University of Nebraska Medical Center, Omaha, NE
6NIH, Bethesda, MD

Samantha Hurwitz, PhD1, Tatiana Fourfouris, MSc1, Rachel Friedmann, DO1*, Ki Jun Lee, MSc1, Zesheng Wan, PhD1*, Sarah Richmann, MD PhD2*, Babak Moghimi, MD3*, Fariba Navid, MD4*, Justine Delgado, PhD5*, Chintan Parekh, MD6, Deepa Bhojwani, MD7 and Yong-Mi Kim, MD, PhD, MPH1

1Children's Hospital of Los Angeles, University of Southern California, Los Angeles, CA
2Children's Hospital Los Angeles, University of Southern California, Los Angeles
3Children’s Hospital Los Angeles, Los Angeles, CA
4Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA
5Iterion Therapeutics, Houston
6City of Hope, Beckman Research Institute, Duarte
7Hematology/Oncology, Children's Hospital of Los Angeles, Los Angeles, CA

Donia M. Moujalled, PhD1,2*, Seong Lin Khaw, MBBS, PhD, FRACP2,3,4, Teresa Sadras, PhD5*, Giovanna Pomilio1,2*, Thomas Morley1,2*, Veronique Litalien1,2*, Louise Ludlow, PhD6*, Paul G. Ekert, MBBS, PhD, FRACP5,7 and Diane Hanna, MD PhD2,3,8

1The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
2Department of Medical Biology, The University of Melbourne, Melbourne, Australia
3Murdoch Children’s Research Institute, Melbourne, VIC, Australia
4Royal Children's Hospital, Melbourne, Australia
5Peter MacCallum Cancer Centre, Melbourne, VIC, Australia
6Royal Children’s Hospital, Melbourne, Australia
7Children’s Cancer Institute, Sydney, Australia
8Children's Cancer Centre, The Royal Children's Hospital Melbourne, Parkville, VIC, Australia

*signifies non-member of ASH