Waseem Gul Lone, PhD^1*, Alyssa Bouska, PhD^1*, Tayla B Heavican-Foral, PhD², Tyler A Herek, Ph.D^1*, Ab Rauf Shah, Ph.D^1*, Abdul Rouf Mir, PhD^1*, Mahfuza Afroz Soma, MS^1*, Dylan T. Jochum, BS¹, Ruimeng Yang, PhD^3*, Xuxiang Liu, PhD^4*, Jeffrey Cannatella, M.D.^1*, Catalina Amador, MD^5*, Andrew L. Feldman, MD⁶, Wing Chung Chan, MD⁴ and Javeed Iqbal, PhD, MSc^1*

¹Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE
²Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
³Department of Pathology, City of Hope National Medical Center, Los Angeles, AL
⁴Department of Pathology, City of Hope National Medical Center, Duarte, CA
⁵University of Miami, Miami, FL
⁶Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN

Xuxiang Liu, PhD^1*, Pin Yu Hou, MS^2*, Krystie Chew^3*, Ruimeng Yang, PhD^3*, Anurag Kumar, PhD^3*, Jaehyuk Choi, MD, PhD⁴, Javeed Iqbal, PhD, MSc^5* and Wing Chung Chan, MD¹

¹Department of Pathology, City of Hope National Medical Center, Duarte, CA
²City of Hope National Medical Center, Duarte
³City of Hope National Medical Center, Duarte, CA
⁴Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL
⁵Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE

Robert M Chavez^1,2*, Doris R. Powell^1*, Kiran Lakhani^1*, John Attelah^1*, Erin Flynt, PhD^3*, Terry Connolly, PhD^3*, Mark Hamilton, MD⁴, George Mulligan, PhD⁴, Daniel Auclair, PhD^4*, Jonathan Keats, PhD^5*, Paula M Vertino, PhD, BS^6*, Lawrence H. Boise, PhD¹, Sagar Lonial, MD^7*, Karen N Conneely, PhD^2* and Benjamin G. Barwick, PhD¹

¹Department of Hematology and Medical Oncology, Winship Cancer Institute, Atlanta, GA
²Department of Human Genetics, Emory University School of Medicine, Atlanta, GA
³K36 Therapeutics, Cambridge, MA
⁴Multiple Myeloma Research Foundation, Norwalk, CT
⁵Translational Genomics Research Institute, Phoenix, CA
⁶University of Rochester, Rochester, NY
⁷Winship Cancer Institute, Atlanta, GA

Anurag Kumar, PhD^1*, Qi Wei, MD^2*, Ruimeng Yang, PhD^3*, Xuxiang Liu, PhD^4*, Jibin Zhang, Ph.D.^5*, Alyssa Bouska, PhD^6*, Javeed Iqbal, PhD, MSc^6* and Wing Chung Chan, MD⁴

¹Anatomy Pathology, National Medical Centre City of Hope, Duarte, CA
²Guangzhou Dadao North Street NO. 1838, Guangzhou, Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangzhou, China
³City of Hope National Medical Center, Duarte, CA
⁴Department of Pathology, City of Hope National Medical Center, Duarte, CA
⁵National Medical Centre City of Hope, Duarte, CA
⁶Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE

Linda Resar, MD¹, Jung-Hyun Kim, PhD^2*, Li Z Luo, PhD^3*, Katharina Hayer^4*, Camilo Arenas Merizalde, BS^5*, Leslie Cope, PhD^6*, Andrei Thomas-Tikhonenko, PhD^7,8 and Sarah K Tasian, MD⁹

¹Division of Hematology, Departments of Medicine, Oncology & Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD
²The Johns Hopkins University School of Medicine, Baltimore, MD
³Department of Medicine, Division of Hematology, The Johns Hopkins University School of Medicine, Baltimore, MD
⁴Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA
⁵Children's Hospital of Philadelphia, Philadelphia
⁶Johns Hopkins University School of Medicine, Baltimore, MD
⁷Division of Cancer Pathobiology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA
⁸Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA
⁹Division of Oncology & Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA

Ruimeng Yang, PhD^1*, Xuxiang Liu, PhD^2*, Jibin Zhang, Ph.D.^3*, Abdul Rouf Mir, PhD^4*, Waseem Gul Lone, PhD^4*, Yuping Li, PhD^5*, Krystie Chew^3*, Claire Wu^6*, Jasmine Zain, MD⁷, Joo Y Song, MD^2*, Javeed Iqbal, PhD, MSc^4* and Wing Chung Chan, MD²

¹Department of Pathology, City of Hope National Medical Center, Los Angeles, AL
²Department of Pathology, City of Hope National Medical Center, Duarte, CA
³City of Hope National Medical Center, Duarte, CA
⁴Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE
⁵Anatomy Pathology, National Medical Centre City of Hope, Duarte, CA
⁶City of Hope, Los Angeles, China
⁷City of Hope, Duarte, CA

Mrinal Joshirao, MD^1,2, Inge Van Der Werf^2*, Jessica Pham, BS^2*, Antonio W Ruiz, BS^2*, Neha Katragadda, BS^2*, Emma E Klacking, BS^2*, Elsa Molina, PhD^3*, Ludmil Alexandrov, PhD^4*, Thomas Whisenant, PhD^5* and Catriona Jamieson, MD, PhD⁶

¹Rady Children's Hospital, University of California San Diego, San Diego, CA
²Division of Regenerative Medicine, Department of Medicine, and Sanford Stem Cell Institute, UCSD, La Jolla, CA
³Next Generation Sequencing & Genomics Core, Salk Institute for Biological Studies, La Jolla, CA
⁴Bioengineering, Center for Molecular Medicine, and Sanford Stem Cell Institute, UCSD, La Jolla, CA
⁵Center for Computational Biology and Bioinformatics, UCSD, La Jolla, CA
⁶Sanford Stem Cell Institute, CIRM UC San Diego Alpha Stem Cell Clinic, La Jolla, CA

Soo Yeon Hwang, PhD, PharmD^1*, Helgi Nikoli^2*, Selina Chen-Kiang, PhD³, Caitlin Gribbin, MD^4*, Peter Martin, MD⁴ and Jihye Paik, PhD⁵

¹Pathology, Weill Cornell Medicine, New york, NY
²Weill Cornell Medicine, New york, NY
³Weill Cornell Medicine, New York, NY
⁴Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, NY
⁵Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY

Marina E Michaud¹, Jodi Dougan^2*, Dailia B. Francis, MD, PhD³, Mojtaba Bakhtiari, MD^1*, Christopher C. Porter, MD^4* and Manoj Bhasin, PhD¹

¹Department of Pediatrics, Emory University, Atlanta, GA
²Department of Pediatrics, Emory University School of Medicine, Atlanta, GA
³Department of Pediatrics, Emory University School of Medicine, Brookhaven, GA
⁴Aflac Cancer & Blood Disorders Center at Children's Healthcare of Atlanta, Atlanta, GA

Areya Tabatabai^1*, Sebastian Klein^1*, Svenja Höfmann^2*, Tanja Zhou^1*, Felix Theiss^3*, Ruth Flümann, MD^4*, Michael Möllmann^1*, Maximilian Hartnack^3*, Stefanie Kesper^3*, Aastha Arora^1*, Gero Knittel, PhD^1* and Hans Christian Reinhardt, MD⁵

¹Department of Hematology and Stem Cell Transplantation, University Hospital Essen, Essen, NRW, Germany
²Department of Hematology and Stem Cell Transplantation, University Hospital Essen, Essen, Germany
³Hematology and Stem Cell Transplantation, University Hospital Essen, Essen, Germany
⁴Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Cologne, NRW, Germany
⁵Department of Hematology and Stem Cell Transplantation, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

Deborah Piffaretti, PhD^1*, Martin Richard Faderl, PhD^1*, Federico Jauk, MD^1*, Adalgisa Condoluci, MD^1,2, Lodovico Terzi Di Bergamo^1*, Gabriela Forestieri^1*, Ricardo Koch, PhD^1*, Katia Pini^1*, Joyce Marques de Almeida, MD^1*, Ilaria Romano, MD^1,2, Matin Salehi^1*, Alessio Bruscaggin, PhD^1*, Simone Bocchetta, PhD^1*, Georgia Alice Galimberti^1*, Maria Cristina Pirosa, MD^1,2, Alexandar Tzankov, MD, PhD^3*, Emanuele Zucca, MD^4,5 and Davide Rossi, MD, PhD^1,2,4

¹Institute of Oncology Research, Laboratory of Experimental Hematology, Bellinzona, Switzerland
²Clinic of Hematology, Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland
³Medical Genetics and Pathology, University of Basel, Basel, Switzerland
⁴Università della Svizzera italiana, Faculty of Biomedical Science, Lugano, Switzerland
⁵Division of Medical Oncology, Oncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale, Bellinzona, Switzerland

Hiroyuki Murakami^1*, Ryota Chijimatsu, PhD^2*, Hideki Ujiie^3*, Yusuke Naoi, MD^1*, Kazutaka Sunami, MD, PhD⁴, Kazuhiko Yamamoto, MD, PhD^5*, Soichiro Fujii, MD, PhD^6*, Tomofumi Yano, MD, PhD^7*, Keisuke Seike, MD, PhD^8*, Hideaki Fujiwara, MD, PhD⁸, Noboru Asada, MD, PhD⁸, Nobuharu Fujii, MD, PhD^9*, Ken-ichi Matsuoka, MD, PhD^8*, Tomohiro Urata, MD^1*, Kazuhiro Ikeuchi, MD^1*, Hiroki Kobayashi, MD^10*, Yasuharu Sato, PhD^11*, Shuta Tomida, PhD^12*, Yoshinobu Maeda, MD, PhD¹ and Daisuke Ennishi, MD, PhD¹³

¹Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
²Center of Comprehensive Genomic Medicine, Okayama University Hospital, Okayama, Japan
³Department of Molecular Hematopathology, Okayama University Graduate School of Health Sciences, Okayama, Japan
⁴Department of Hematology, NHO, Okayama Medical Center, Okayama, Japan
⁵Department of Hematology and Oncology, Okayama City Hospital, Okayama, Japan
⁶Department of Hematology, Japanese Red Cross Okayama Hospital, Okayama, Japan
⁷Department of Internal Medicine, Okayama Rosai Hospital, Okayama, Japan
⁸Department of Hematology and Oncology, Okayama University Hospital, Okayama, Japan
⁹Division of Blood Transfusion, Okayama University Hospital, Okayama, Japan
¹⁰Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, OKA, Japan
¹¹Department of Molecular Hematopathology, Okayama University, Okayama, Japan
¹²Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sci, Okayama, JPN
¹³Center for Comprehensive Genomic Medicine, Okayama University Hospital, Okayama, Japan

Meagan Vacek, DO¹, Jacqelyn Nemechek, PhD^2*, Irina Pushel, PhD^3*, Bradley Thornton^4*, Molly Leyda^2*, Priyanka Prem Kumar^4*, Midhat S Farooqi, MD, PhD^3,5,6*, Erin M. Guest, MD⁷, Jay Vivian, PhD^4,5,8* and John M. Perry, PhD^2,5,8

¹Division of Hematology/Oncology/Bone Marrow Transplant, Children's Mercy Hospital, Kansas City, MO
²Division of Hematology/Oncology/Bone Marrow Transplant, Children's Mercy Kansas City, Kansas City, MO
³Genomic Medicine Center, Children's Mercy Kansas City, Kansas City, MO
⁴Division of Clinical Genetics, Children's Mercy Kansas City, Kansas City, MO
⁵University of Missouri - Kansas City, Kansas City, MO
⁶Department of Pathology, University of Kansas Medical Center, Kansas City, KS
⁷Hematology/Oncology/BMT, Children's Mercy Kansas City, Kansas City, MO
⁸University of Kansas Medical Center, Kansas City, KS

Makoto Iwasaki, MD, PhD¹, Caroline MacVicar, BA^2*, Anna B Rider, BSc^3*, Aliyah R. Sohani, MD^4*, Valentina Nardi, MD^5*, Josie G Ford, BSc⁶, Kusha Chopra, BA^2*, Jeffrey A. Barnes, MD, PhD⁷ and Salvia Jain, MD⁴

¹Massachusetts General Hospital Cancer Center, Boston, MA
²Department of Medicine, Massachusetts General Hospital, Boston, MA
³Department of Pathology, Massachusetts General Hospital, Boston, MA
⁴Division of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA
⁵Pathology Division, Harvard Medical School, Boston, MA
⁶Department of Medicine, Massachusetts General Hospital, Farmington, CT
⁷Center for Lymphoma, Massachusetts General Hospital Cancer Center, Boston, MA

Amna De Bolòs, MS^1,2*, Maria Carreras-Caballé^1*, Marta Sureda-Gómez^1*, Marta Leonor Rodríguez^1*, Stella Charalampopoulou^1*, Robert Albero^1*, Alba Maiques-Diaz^1*, Heribert Playà-Albinyana^2,3,4*, Dolors Colomer^1,2,3,5*, José Ignacio Martín-Subero^1,5,6*, Elías Campo^1,2,3,5,6, David Reverter^6,7*, Josep Villanueva^2,8* and Virginia Amador^1,2*

¹Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
²Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain
³Universitat de Barcelona (UB), Barcelona, Spain
⁴Institut D'Investigacions BiomèDiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain
⁵Hematopathology Section, Pathology Department, Hospital Clínic de Barcelona, Barcelona, Spain
⁶Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain
⁷Institut de Biotecnologia i de Biomedicina (IBB) and Dept. de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Bellaterra, Spain
⁸Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain