Anna Collado Gimbert, MD1,2*, Sara Reidel, MSc1*, Patricia Alonso de Apellániz, MSc3*, Federico Alvarez, Prof, PhD4*, Borja Arroyo Galende, MSc5*, David Beneitez, MD6,7*, Bart J. Biemond, MD, PhD8, Maria Paola Boaro, MD9*, Betzabel Cajiao Garcia, MSc10*, Gastone Castellani, PhD11*, Elena Cela, MD, PhD12*, Marjon H. Cnossen, MD, PhD13*, Piero Fariselli, PhD14*, Karin Fijnvandraat, MD, PhD15*, Béatrice Gulbis, MD, PhD16,17*, Amira Idrizovic, MSc, PhDc1,18*, Petros Kountouris, PhD19*, Vincent Malcor Deydier De Pierrefeu, PhD20*, Sandra Manceau, PhD21*, Elisabetta Mezzalira, RN, MS, PhDc22*, Erfan Nur, MD, PhD23, Kalia Orphanou, PhD24*, Juan Parras, PhD25*, Salvador Payán-Pernía, MD26*, Anne-Laure Pham Hung D'Alexandry D'Orengiani, PhD27*, Minke A.E. Rab, MD, PhD28, Giulia Reggiani, MD29*, Anita W. Rijneveld, MD, PhD30, Cesare Rollo, PhD14*, Anna Ruiz Llobet, MD31*, Tiziana Sanavia, PhD14*, Saskia EM Schols, MD, PhD32*, Stella Tamana, PhD24*, Marissa J.M. Traets, MD33*, Silvia Uribe, PhD34*, Sigrid van der Veen, MSc35*, Santiago Zazo, Prof., PhD36*, Pablo Bartolucci, MD, PhD37*, Mariane De Montalembert, MD, PhD38, Raffaella Colombatti, MD, PhD39*, Eduard J. Van Beers, MD, PhD40,41 and Maria Del Mar Mañú Pereira1*
1Rare Anemia Disorders Research Laboratory, Cancer and Blood Disorders in Children, Vall d'Hebron Research Institute / Vall d'Hebron University Hospital, Barcelona, Spain
2Pediatric Oncology and Hematology, Vall d'Hebron Barcelona Hospital, Barcelona, Spain
3Information Processing and Telecommunications Center, Universidad Politécnica de Madrid, Madrid, Spain
4Universidad Politécnica de Madrid, Madrid, Spain
5Grupo de Aplicación de las Telecomunicaciones Visuales, Universidad Politécnica de Madrid, Madrid, Spain
6Hematology Department, Vall d'Hebron Hospital Universitari/Vall d'Hebron Research Institute (VHIR)/Vall d'Hebron Institute of Oncology (VHIO)/Universitat Autònoma de Barcelona (UAB)/ERN-EuroBloodNet, Barcelona, Spain
7Vall d'Hebron Institute of Oncology, Vall d'Hebron Hospital Universitari, Universitat Autonoma de Barcelona, Barcelona, Spain
8Department of Hematology, Amsterdam University Medical Centers, Amsterdam, Netherlands
9Department of Women’s and Children’s Health, Padova University, Padova, Italy
10Center for Benign Hematology, Thrombosis and Hemostasis - Van Creveldkliniek, University Medical Center Utrecht, Utrecht University, University Medical Center Utrecht, Utrecht, Netherlands
11Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
12Pediatric Hematology and Oncology, Hospital Gregorio Marañón. Universidad Complutense de Madrid, Madrid, Spain
13Department of Pediatric Hematology and Oncology, Erasmus MC Sophia Children’s Hospital, Erasmus University Medical Center, Rotterdam, Netherlands
14Computational Biomedicine Unit, Department of Medical Sciences, University of Torino, Turin, Italy
15Department of Pediatric Hematology, Amsterdam UMC, Emma Children's Hospital, Amsterdam, Netherlands
16Hopital Erasme U.L.B, Brussels, BEL
17Centre of Human genetics, Hôpital Universitaire de Bruxelles, Université Libre de Bruxelles, Brussels, Belgium
18Genetics and Microbiology department, Universitat Autonoma de Barcelona, Barcelona, Spain
19Molecular Genetics Thalassaemia Department, The Cyprus Institute of Neurology and Genetics, Nicosia, CYP
20Sickle Cell Referral Center, Department of Internal Medicine, Henri-Mondor University Hospital- UPEC, AP-HP, Creteil, France
21Laboratoire d'Excellence GR-Ex, Paris, France., Paris, France
22Pediatric Hematology, Oncology and Stem Cell Transplant Division, Maternal and Child Health Department, Università degli Studi di Padova, Padova, Italy
23Department of Hematology, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands
24Molecular Genetics Thalassaemia Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus
25Information Processing and Telecommunications Center, ETSI Telecomunicación, Universidad Politécnica de Madrid, Madrid, Spain
26Servicio de Hematologia, Hospital Universitario Virgen del RocÍo, Instituto de Biomedicina de Sevilla (IBiS), Sevilla, Spain
27University Paris-Est-Créteil, IMRB, Inserm U955, Laboratory of excellence LABEX, Henri Mondor University Hospitals, APHP, Sickle Cell Referral Center-UMGGR, Créteil, FRA
28Department of Hematology, University Medical Center Utrecht, Utrecht, Netherlands
29Department of Women’s and Children’s Health, University of Padua, Padova, Italy
30Department of Hematology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, Netherlands
31Pediatric Hematology, Hospital Sant Joan de Déu, Barcelona, Barcelona, ESP
32Department of Hematology, Radboud University Medical Center, Nijmegen, Netherlands
33Central Diagnostic Laboratory - Research, University Medical Center Utrecht, Utrecht, Netherlands
34Escuela Técnica Superior de Ingeniería de Sistemas Informáticos-Departamento de Sistemas Informáticos, Universidad Politécnica de Madrid, Madrid, Spain
35Center for Benign Hematology, Thrombosis and Hemostasis - Van Creveldkliniek, University Medical Center Utrecht, Utrecht, Netherlands
36Centro de I+D+i en Procesado de la Información y Telecomunicaciones (IPTC), Universidad Politécnica de Madrid, Madrid, Spain
37University Paris-Est-Créteil, IMRB, Inserm U955,, Henri Mondor University Hospitals, APHP, Sickle Cell Referral Center-UMGGR, Creteil, France
38Department of General Pediatrics and Pediatric Infectious Diseases, Sickle Cell Center, Necker-Enfants Malades Hospital, Neuilly, France
39Department for Woman's and Child's Health, University of Padova, Padova, Italy
40Department of Hematology, Van Creveldkliniek, University Medical Center Utrecht, Utrecht, Netherlands
41Center for Benign Hematology, Thrombosis and Hemostasis - Van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands