-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

653.O2.6 653. Multiple Myeloma: Clinical and Epidemiological: Decluttering Responses and Dynamic Risk: How Can We Improve Prognostication in Multiple Myeloma?

Symposia: Multiple Myeloma: Clinical and Epidemiological Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Adult, Clinical trials, Combination therapy, Epidemiology, Elderly, Clinical Practice (Health Services and Quality), Clinical Research, Plasma Cell Disorders, Genomics, Health outcomes research, Education, Diseases, Therapy sequence, Real-world evidence, Clinical procedures, Treatment Considerations, Lymphoid Malignancies, Biological Processes, Survivorship, Emerging technologies, Technology and Procedures, Study Population, Human, Imaging, Measurable Residual Disease
Saturday, December 7, 2024: 9:30 AM-11:00 AM
Pacific Ballroom Salons 24-26 (Marriott Marquis San Diego Marina)
Moderators:
Shashank R Cingam, MD, and Meera Mohan, MD,
Disclosures:
Cingam: Pfizer: Research Funding; Janssen: Other: Advisory Board . Mohan: BMS: Consultancy; Sanofi: Consultancy, Research Funding, Speakers Bureau; Janssen: Consultancy; Pfizer: Consultancy; Legend biotech: Consultancy.

This session focus on unravelling dynamic risk assessment in multiple myeloma based on cytogenetic/ molecular markers, assessment of clonal heterogeneity and functional risk based on response. One abstract discusses the limited value of 24-hour urine testing in assessing multiple myeloma response and proposes more efficient methods for response confirmation. These abstracts collectively aim to enhance understanding and improve the clinical management of multiple myeloma, particularly in high-risk disease.
9:30 AM

Joshua Gustine, MD1*, Diana Cirstea, MD2*, Andrew R. Branagan, MD3, Andrew J. Yee, MD1, Marcela Maus, MD4, Matthew J. Frigault, MD1* and Noopur Raje, MD5

1Massachusetts General Hospital, Boston, MA
2Center for Multiple Myeloma, Massachusetts General Hospital, Boston, MA
3Harvard Medical School, Massachusetts General Hospital Cancer Center, Boston, MA
4Massachusetts General Hospital, Harvard Medical School, Boston, MA
5Center for Multiple Myeloma, Massachusetts General Hospital, Harvard Medical School, Boston, MA

9:45 AM

Xinhe Shan, MD1 and Sandra Susanibar-Adaniya, MD2,3

1Internal Medicine, Albert Einstein College of Medicine, Bronx, NY
2University of Pennsylvania, Philadelphia
3Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA

10:00 AM

Rahul Banerjee, MD, FACP1,2, Amber R. Fritz, PhD3*, Othman S Akhtar, MD4, Ciara Louise Freeman, PhD, MSc, FRCPC, MRCP5, Andrew J. Cowan, MD2,6, Nina Shah, MD7,8, Heather J. Landau, MD9, Shaji Kumar, MD10, Dan T. Vogl, MD, MS11, Yvonne A. Efebera, MD12, Philip L. McCarthy, MD13, David H. Vesole, MD, PhD14, Adam Mendizabal, PhD3, Amrita Y Krishnan, MD, FACP15, George Somlo, MD16*, Edward A. Stadtmauer, MD17 and Marcelo C. Pasquini, MD, MS18

1University of Washington Fred Hutchinson Cancer Center, Seattle, WA
2University of Washington, Seattle, WA
3The Emmes Company, Rockville, MD
4Division of Hematology and Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI
5Moffitt Cancer Center, Tampa, FL
6Fred Hutchinson Cancer Center, Seattle, WA
7AstraZeneca, South San Francisco, CA
8University of California San Francisco, San Francisco, CA
9Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
10Division of Hematology, Mayo Clinic, Rochester, MN
11Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
12Blood and Marrow Transplant and Cellular Therapy Program, OhioHealth, Columbus, OH
13Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY
14Lombardi Comprehensive Cancer Center, Medstar Georgetown Medical Center, Washington, DC, DC
15City of Hope Comprehensive Cancer Center, Duarte, CA
16City of Hope Cancer Center, Duarte, CA
17Hospital of the University of Pennsylvania, Philadelphia, PA
18BMT and Cellular Therapy Program, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI

10:15 AM

Angelo Belotti, MD1*, Barbara Frittoli, MD2*, Sofia Terlizzi3*, Rossella Ribolla, MD4*, Claudia Crippa, MD4*, Chiara Saeli, MD5*, Samantha Ferrari, MD1*, Annalisa Peli, MD4*, Nicola Bianchetti, MD1*, Chiara Bottelli, MD1*, Chiara Cattaneo, MD6, Carmela Carbone, MD7*, Alessandro Gullino, MD7*, Marco Chiarini, PhD8*, Viviana Giustini, MSc9*, Aldo Roccaro, MD, PhD10, Luigi Grazioli, MD11* and Alessandra Tucci, MD1

1Department of Hematology, ASST Spedali Civili di Brescia, Brescia, Italy
2Department of Radiology, ASST Spedali Civili, Brescia, ITA
3Department of Hematology, ASST Spedali Civili di Brescia, University of Brescia, Brescia, Italy
4Department of Hematology, ASST Spedali Civili di Brescia, Brescia, ITA
5Department of Radiology, ASST Spedali Civili di Brescia, Brescia, Italy
6Hematology, ASST Spedali Civili, Brescia, Italy
7Department of Radiology, University of Brescia, Brescia, Italy
8Clinical Chemistry Laboratory, Diagnostic Department, ASST Spedali Civili Di Brescia, Brescia, Italy
9Clinical Chemistry Laboratory, Diagnostic Department, ASST Spedali Civili di Brescia, Brescia, ITA
10Clinical Trial Center, Translational Research and Phase I Unit, ASST Spedali Civili di Brescia, Brescia, BS, Italy
11Department of Radiology, ASST Spedali Civili di Brescia, Brescia, ITA

10:30 AM

Jean-Sébastien Claveau, MD1,2, Angela Dispenzieri, MD1, Prashant Kapoor, MD3, Moritz Binder, MD1, Francis Buadi, MD1, David Dingli, MD, PhD1, Amie Fonder, PA-C, MS1*, Morie A. Gertz, MD1, Wilson I. Gonsalves, MD1, Suzanne R Hayman, MD1, Miriam Hobbs, APRN, CNP, DNP1*, Yi Lisa Hwa, APRN, DNP, CNP1, Taxiarchis Kourelis, MD1, Martha Lacy, MD1*, Nelson Leung, MD1, Yi Lin, MD, PhD1, Rahma M Warsame, MD1, Robert A. Kyle, MD1, S. Vincent Rajkumar, MD1* and Shaji Kumar, MD1

1Division of Hematology, Mayo Clinic, Rochester, MN
2Hôpital Maisonneuve-Rosemont, Université de Montréal, Hematology-Oncology and Cell Therapy University Institute, Montreal, QC, Canada
3Mayo Clinic, Rochester, MN

10:45 AM

Maximilian Merz, MD1, Ema Pozek2*, Kaya Miah3*, Uta Bertsch, MD4*, Britta Besemer, MD5*, Mathias Hänel, MD6, Julia Krzykalla7*, Roland Fenk, MD, PhD8*, Jana Schlenzka, MD9*, Markus Munder10*, Christine Hanoun11*, Christoph Mann, MD12*, Niels Weinhold, PhD13*, Christof Scheid, MD14, Roland Schroers, MD15*, Igor Wolfgang Blau, MD, PhD16*, Stefanie Huhn, PhD9*, Dirk Hose, MD, PhD17, Anna Jauch, PhD18*, Christina Kunz2*, Ivana von Metzler, MD19*, Aneta Schieferdecker20*, Jörg Thomalla, MD21*, Peter Reimer, MD22*, Rolf Mahlberg, MD23*, Ullrich Graeven, MD24*, Stephan Kremers25*, Uwe Martens, MD26*, Manfred Hensel, MD27*, Axel Benner28*, Andrea Seidel-Glätzer29*, Katja C. Weisel, MD30, Marc S. Raab31*, Hans Salwender, MD32*, Hartmut Goldschmidt, MD33 and Elias K. Mai, MD34*

1Department for Hematology, Cell Therapy, Hemostaseology and Infectious Diseases, University of Leipzig Medical Center, Leipzig, Germany
2German Cancer Research Center, Heidelberg, DEU
3German Cancer Research Center (DKFZ), Heidelberg, DEU
4National Center for Tumor Diseases Heidelberg, Heidelberg, Germany
5Department of Internal Medicine II, University Hospital Tübingen, Tübingen, Germany
6Department of Internal Medicine III, Klinikum Chemnitz, Chemnitz, Germany
7German Cancer Research Centre, Heidelberg, DEU
8Department of Haematology, Oncology, and Clinical Immunology, University Hospital Düsseldorf, Düsseldorf, Germany
9Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany
10Third Department of Medicine, University Medical Center of the Johannes Gutenberg University, Mainz, Germany
11Department of Hematology and Stem Cell Transplantation, West German Cancer Center and German Cancer consortium (DKTK partner site Essen), University Hospital Essen, University of Duisburg-Essen, Essen, Germany
12Department of Haematology, Oncology and Immunology, Philipps-University Marburg, Marburg, Germany
13Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Heidelberg, Germany
14Department of Internal Medicine I, University Hospital Cologne, Cologne, Germany
15Knappschaftskrankenhaus Bochum, University Hospital Bochum, Bochum, Germany
16Medical Clinic, Charité University Medicine Berlin, Berlin, Germany
17Department of Hematology and Immunology, Myeloma Center Brussels, & Labor für Myelomforschung, VUB Brussels, Brussels, Belgium
18Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany
19Department of Medicine II – Hematology and Oncology, Goethe-University Frankfurt, University Hospital, Frankfurt am Main, Germany
20Department of Oncology, Hematology and Bone Marrow Transplantation with Section of Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
21Hematology / Oncology Center, Koblenz, Germany
22Evang. Kliniken Essen-Mitte, Evang. Krankenhaus Essen-Werden, Essen, Germany
23Internal Medicine I, Hospital Mutterhaus der Borromäerinnen, Trier, Germany
24Medical Clinic I, Hospital Maria Hilf GmbH, Mönchengladbach, Germany
25Marienhaus, Saarlouis, DEU
26Hematology, Oncology, Palliative Care, SLK Clinic Heilbronn, Heilbronn, Germany
27Mannheimer Onkologie Praxis, Mannheim, Germany
28Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany
29Coordination Centre for Clinical Trials (KKS) Heidelberg, Heidelberg, Germany
30Department of Oncology, Hematology and Bone Marrow Transplantation with Section of Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, Hamburg, Germany
31German Cancer Research Center, Heidelberg, Germany
32Asklepios Tumorzentrum Hamburg, AK Altona, AK St Georg, Hamburg, Germany
33Internal Medicine V, Hematology, Oncology and Rheumatology, GMMG Studygroup, Heidelberg University Hospital, Heidelberg, Germany
34Medicine V, University Hospital Heidelberg, Heidelberg, Germany

*signifies non-member of ASH