-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

703.O2.6 703. Cellular Immunotherapies other than CAR-T Cells: Basic and Translational: Novel Cell Platforms and Delivery Strategies

Symposia: Cellular Immunotherapies other than CAR-T Cells: Basic and Translational Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Fundamental Science, Bleeding and Clotting, Lymphoid Leukemias, ALL, Translational Research, Hemophilia, Genetic Disorders, Diseases, Treatment Considerations, Biological therapies, Immunology, Lymphoid Malignancies, Emerging technologies, Biological Processes, Technology and Procedures, Miscellaneous Cellular Therapies, Gene editing
Saturday, December 7, 2024: 9:30 AM-11:00 AM
Ballroom 20AB (San Diego Convention Center)
Moderators:
Kazusa Ishii, MD, MPH, National Cancer Institute and Bernhard Gentner, MD, Ludwig Institute for Cancer Research, University of Lausanne (UNIL) and Lausanne University Hospital (CHUV)
Disclosures:
Gentner: Genenta Science: Consultancy, Current equity holder in publicly-traded company, Honoraria, Membership on an entity's Board of Directors or advisory committees, Patents & Royalties: US10287579B2.

For this session, we have selected six top scoring abstracts for oral presentation that develop novel engineered cell therapy approaches, or that investigate novel cell based delivery approaches.
9:30 AM

Nathan E Welty, MD, PhD1, Patrick Mellors, MD1, Olga Shestova, PhD1*, Darryl Sams2*, Om Gandhi3*, Joelle Kim4*, Xinhe Shan, MD5 and Saar Gill, MD, PhD1

1Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
2Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
3University of Pennsylvania, Philadelphia
4Baylor College of Medicine, Houston, TX
5Internal Medicine, Albert Einstein College of Medicine, New York City, NY

9:45 AM

Aditi Majumder1*, MD Ehsanul Kabir2*, Ho Sun Jung, Ph.D3*, Yuju Jun4*, Jue Zhang5*, Anna Huttenlocher4*, Christian Capitini6, James Thomson7* and Igor Slukvin, MD3,8,9

1Wisconsin National Primate Research Center, Madison, WI
2Wisconsin National Primate Research Center, University of Wisconsin Madison, Madison, WI
3Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI
4University of Wisconsin Madison, Madison, WI
5Morgridge Instituet for Research, Madison, WI
6University of Wisconsin-Madison, Madison, WI
7Morgridge Institute for Research, Madison, WI
8Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI
9Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI

10:00 AM

Yuanyuan Tian, PhD1*, Bei Jia, MD, PhD2*, Che Young Lee, BS1*, Qingrong Huang, PhD1*, Chenchen Zhao, MD2*, Ciril Abraham, BS1*, Wenbin Mo, MMSc1*, Mimi Chen, PhD1*, Ying WANG1*, Hong Zheng, MD, PhD2 and Yi Zhang, MD, PhD1

1Center for Discovery and Innovation, Hackensack University Medical Center, Nutley, NJ
2Penn State Cancer Institute, Penn State University College of Medicine, Hershey, PA

10:15 AM

Anja F Hohmann1*, Timothy Mullen, PhD1*, Jasmine Edelstein, PhD1*, Swati Singh1*, Alexis Hubaud, PhD1*, Sarah Leach, PhD1*, Tracy Huang, PhD1*, Ella Liberzon, PhD1*, Wayne Bainter1*, Sean Keegan1*, Caroline Bullock1*, Shivani Bhawsar1*, Michael D Leiken1*, Katherine Molloy1*, Ryan Couto1*, Sakshisingh Thakur1*, Charuta Yadav1*, Troy Patterson1*, Amy Lundberg1*, Megan L Brophy, PhD1*, Toshiro K Ohsumi, PhD1*, Sol Shenker, PhD2*, Monika Musial-Siwek, PhD1*, Adam S Lazorchak, PhD1*, Sean Arlauckas, PhD1*, Hanlan Liu, PhD1* and Richard A Morgan, PhD1

1Be Biopharma, Cambridge, MA
2Shenker Bioinformatics LLC, Belmont, MA

10:30 AM

Xiuiu Yang, MD1,2*, Shanwei Ye1*, Qian Xu, MD/PhD1*, Jue Wang3*, Caroline Markmann, MD/PhD4*, Lingfeng Zhang1*, Shujia Zhang1*, Xinyue Deng, MD/PhD5*, Jiali Cheng, MD/PhD1*, Jia Wu1*, Vijay Bhoj, MD/PhD4*, Zheng Zhang, MD/PhD6* and Liang Huang, MD/PhD1,2,7

1Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, China, Wuhan, China
2State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China
3Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
4Department of Pathology & Laboratory Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA 19104, USA, Philadelphia, PA
5Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430022, Wuhan, China, Wuhan, China
6Department of Orthopedics, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China, Wuhan, China
7Tianjin Institutes of Health Science, Tianjin 301600, China, Tianjin, China

10:45 AM

Sophie Jamet1*, Huiyuan Zhang, PhD2*, Sally Ditzler2*, Kikki Tucker2*, Peter Chong2*, Clara Libbrecht, MD, PhD2*, Ray Ruff2*, Hailey Hentschel2*, Bianka Haro2*, Benjamin J Huang, MD3, James Olson, MD PhD2*, Jason Price, PhD2* and Mignon L. Loh, MD, PhD4

1Ben Towne Center for Childhood Cancer and Blood Disorders Research, Seattle Children's Research Insitute, Seattle, WA
2Ben Towne Center for Childhood Cancer and Blood Disorders Research, Seattle Children's Research Institute, Seattle, WA
3Department of Pediatrics, University of California, San Francisco, San Francisco, CA
4Ben Towne Center for Childhood Cancer Research, Seattle Children’s Hospital, Fred Hutch Cancer Center, University of Washington, Seattle, WA

*signifies non-member of ASH