Heather Fairfield, MS^1,2*, Haylee Duval^1,3*, Kaitlyn Belknap^1,4*, Katie Knox^1,3*, Kehinde Abayomi^1,5*, Sergey Ryzhov^1,2,5* and Michaela R Reagan, PhD^2,5,6

¹Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME
²Tufts University School of Medicine, Boston, MA
³University of Southern Maine, Portland, ME
⁴University of New England College of Osteopathic Medicine, Biddeford, ME
⁵University of Maine Graduate School of Biomedical Sciences and Engineering, Orono, ME
⁶Center for Molecular Medicine, MaineHealth Institute for Research, South Portland, ME

Sojeong Kim^1*, Jeong-Eun Kwak^1*, June-Young Koh^2*, Hye Won Kook^1*, Yu Ri Kim, MD¹, Soo Jeong Kim, MD^1*, Jin Seok Kim, MD, PhD^3*, June-Won Cheong, MD, PhD⁴, Min Goo Lee^1*, Hoyoung Lee^5*, Eui-Cheol Shin^5*, Kihyun Kim, MD^6*, Haerim Chung, MD^1*, Il-Kyu Choi^7*, Jeong Seok Lee, MD, PhD^5* and Hyunsoo Cho, MD, PhD^8*

¹Yonsei University College of Medicine, Seoul, Korea, Republic of (South)
²Inocras, San Diego
³Yonsei University College of Medicine, Severance Hospital, Seoul, Korea, Republic of (South)
⁴Division of Hematology, Department of Internal Medicine, Yonsei University College of Medicine, Severance Hospital, 50 Yonsei-ro, Seodaemun-gu, Seoul, Korea, Republic of (South)
⁵KAIST, Daejeon, Korea, Republic of (South)
⁶Sungkyunkwan University, Samsung Medical Center, Seoul, Korea, Republic of (South)
⁷DGIST, Daegu, Korea, Republic of (South)
⁸Yonsei University College of Medicine, Seoul, South Korea

Kane A Foster, MSc^1*, Elise Rees, PhD^2*, Louise Ainley, BMBCh^2*, Eileen M Boyle, MBChB, PhD³, Lydia Sarah Hui Lee, MD PhD^4*, Gwennan Ward^2*, Daria Galas-Filipowicz^2*, Anna Mikolajczak^5*, Emma J Lyon^3*, Dylan Jankovic^2*, Jasmine Rahman^2*, Mahima Turakhia^2*, Imran Uddin^2*, Gordon Beattie^6*, Yvette Hoade, BSc^7*, Catherine Zhu^2*, James L Reading^2*, Ieuan Walker, MBBS, MSc, BSc, MRCP, FRCPath⁸, Michael A. Chapman, PhD^8,9, Karthik Ramasamy, MD, PhD¹⁰, Javier Herrero, PhD^2*, Benny Chain, PhD^11*, Sergio A Quezada, PhD FMedSci^12* and Kwee Yong, MD, PhD³

¹Cancer Institute, University College London, London, ENG, United Kingdom
²Cancer Institute, University College London, London, United Kingdom
³UCL Cancer Institute, University College London, London, United Kingdom
⁴Research Department of Haematology, University College London, London, United Kingdom
⁵Department of Hematology, UCL Cancer Institute, London, United Kingdom
⁶UCL Cancer Institute, London, United Kingdom
⁷Haematology, Cancer Institute, University College London, London, United Kingdom
⁸MRC Toxicology Unit, University of Cambridge, Cambridge, United Kingdom
⁹Department of Haematology, University of Cambridge, Cambridge, United Kingdom
¹⁰Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
¹¹Institute of Infection and Immunity, University College London, London, United Kingdom
¹²Research Department of Haematology, University College London Cancer Institute, London, United Kingdom., London, United Kingdom

Marta Larrayoz, PhD^1*, Elena Arriazu, PhD^1*, Aintzane Zabaleta, PhD^1*, Carmen Roncal, PhD^1*, Ibon Tamayo, PhD^2*, Diana Llopiz, PhD^3*, Maddalen Jimenez, PhD^1*, Carla Castro^3*, Jon Celay, PhD^1*, Carmen Vicente, PhD^1*, Camila Guerrero, PhD^1*, Sonia Sanz^1*, Maria J Garcia-Barchino, PhD^1*, Naroa Barrena^1*, Noemi Puig, PhD⁴, Maria Teresa Cedena Romero, MD, PhD^5*, Maria Jose Calasanz, PhD^1*, Paula Rodríguez-Otero, MD, PhD^1*, Jesús F. San-Miguel, MD, PhD¹, Mikel Hernaez, PhD^6*, Xabier Agirre, PhD^1*, Pablo Sarobe, PhD^3*, Felipe Prosper, MD, PhD¹, Bruno Paiva, PhD^1* and Jose A. Martinez-Climent, MD, PhD¹

¹Department of Hematology, Centre for Applied Medical Research, Cancer Center Clinica Universidad de Navarra, University of Navarra, IdiSNA, CIBERONC, Pamplona, Spain
²Computational Biology Program, Center for Applied Medical Research, Cancer Center Clinica Universidad de Navarra, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain, Pamplona, Spain
³Program of Immunology and Immunotherapy, Center for Applied Medical Research, Cancer Center Clinica Universidad de Navarra, IDISNA, CIBEREHD, Pamplona, Spain, Pamplona, Spain
⁴Hospital Universitario de Salamanca, Instituto de Investigacion Biomedica de Salamanca (IBSAL), University of Salamanca, Salamanca, Spain
⁵Department of Translational Hematology, Research Institute Hospital 12 de Octubre (i+12), Hematological Malignancies Clinical Research Unit H120-CNIO, CIBERONC, Madrid, Spain
⁶Computational Biology Program CIMA-Universidad de Navarra, Cancer Center Clinica Universidad de Navarra, IdISNA, Pamplona, Pamplona, Spain

Urvi A. Shah, MD^1,2, Laura Lucia Cogrossi, MS^3,4*, Andriy Derkach, PhD^5*, Francesca Castro, MS^6*, Teng Fei, PhD^7*, Susan DeWolf, MD⁸, Juan-Jose Garces, PhD^9*, Anna Policastro, MS^3,4*, Matteo Grioni^3*, Sofia Sisti, MS^4,10*, Blaslov Jenna^11*, Peter Adintori, MS^6*, Kinga K. Hosszu, PhD^12*, Devin McAvoy^12*, Mirae Baichoo, PhD^13*, Justin Cross, PhD^6*, Aishwarya Anuraj, MBBS^14*, Charlotte Pohl, BA^6*, Ruben Ramos, PhD^6*, Jenny Paredes Sanchez, PhD¹⁵, Brianna Gipson^6*, Kylee H Maclachlan, PhD, BSc, FRACP, FRCPA¹¹, Ana Gradissimo, PhD^6*, Leonardo Boiocchi, MD^6*, Richard Koche, PhD^16*, Ronan Chaligne, PhD^17*, Torin Block, BA^18*, Neha Korde, MD¹¹, Carlyn Rose Tan, MD¹⁹, Malin Hultcrantz, MD, PhD¹¹, Hani Hassoun, MD¹¹, Gunjan L. Shah, MD²⁰, Michael Scordo, MD²¹, Oscar B Lahoud, MD²², David J. Chung, MD, PhD²⁰, Heather J. Landau, MD²³, Jonathan U. Peled, MD, PhD²⁴, Nicola Clementi^4,10*, Marta Chesi, PhD²⁵, P. Leif Bergsagel, MD²⁶, Sham Mailankody, MD, MBBS²⁷, Michael Pollak, MD^28*, Anita D'Souza, MD^29,30, Ola Landgren, MD, PhD³¹, Susan Chimonas, PhD^32*, Sergio Giralt, MD^33,34,35, Saad Z. Usmani, MD^11,33, Neil M. Iyengar, MD, BS, BA^36*, Alexander M. Lesokhin, MD^11,37, Matteo Bellone, MD^38* and Marcel R.M. van den Brink, MD, PhD³⁹

¹Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
²MSKCC, New York, NY
³Cellular immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, Milano, Italy
⁴Vita-Salute San Raffaele University, Milano, Italy
⁵Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY
⁶Memorial Sloan Kettering Cancer Center, New York, NY
⁷Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY
⁸Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁹Memorial Sloan Kettering Cancer Center, New York
¹⁰Laboratory of Microbiology, IRCCS Ospedale San Raffaele, Milano, Italy
¹¹Myeloma Service, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
¹²Department of Pediatrics, Immune Discovery and Modeling Service, Memorial Sloan Kettering Cancer Center, New York, NY
¹³Department of Immunology, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁴Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁵Beckham Research Institute, City of Hope, Los Angeles, CA
¹⁶Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁷Single Cell Analytics and Innovation Lab, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁸Nutritionquest, Berkeley, CA
¹⁹Myeloma Service, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Ardmore, PA
²⁰Transplant and Cellular Therapy Services, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
²¹Transplant and Cellular Therapy Services, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY
²²NYU Perlmutter Cancer Center, NYU Grossman School of Medicine, Brooklyn, NY
²³Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
²⁴Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, NY
²⁵Mayo Clinic Arizona, Scottsdale, AZ
²⁶Division of Hematology/Oncology, Mayo Clinic, Phoenix, AZ
²⁷Myeloma Service, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York
²⁸McGill University, Montreal, QC, CAN
²⁹Center for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI
³⁰Medical College of Wisconsin, Milwaukee, WI
³¹Sylvester Comprehensive Cancer Center, Miami, FL
³²Center for Health Policy and Outcomes, Memorial Sloan Kettering Cancer Center, New York, NY
³³Department of Medicine, Weill Cornell Medical College, New York, NY
³⁴Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York
³⁵Weill Cornell Medical College, Memorial Sloan Kettering Cancer Center, New York, NY
³⁶Memorial Sloan-Ketter Cancer Ctr/NY Presb Hosp (Cornell), New York, NY
³⁷Myeloma & Cell Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
³⁸Cellular Immunology Unit, Division of Immunology, Infectious Diseases and Transplantation, IRCCS Ospedale San Raffaele, Milan, Italy
³⁹Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA

Ross S Firestone, MD, PhD¹, Anish Kumar Simhal, PhD², Devin McAvoy^3*, Eric M Jurgens, MD¹, Juan-José Garcés, PhD^4*, David Nemirovsky^5*, Andriy Derkach, PhD^5*, Kylee H Maclachlan, PhD, BSc, FRACP, FRCPA¹, Malin Hultcrantz, MD, PhD¹, Sham Mailankody, MD, MBBS⁶, Urvi A. Shah, MD¹, Carlyn Rose Tan, MD¹, Neha Korde, MD¹, Hani Hassoun, MD¹, Sridevi Rajeeve, MD¹, Hamza Sloan Hashmi, MD^1*, Heather J. Landau, MD⁷, Michael Scordo, MD⁸, Gunjan L. Shah, MD⁹, Sergio Giralt, MD¹⁰, Benjamin Diamond, MD¹¹, Francesco Maura, MD¹², Kinga K. Hosszu, PhD^3*, David J. Chung, MD, PhD⁹, Ola Landgren, MD, PhD¹³, Saad Z. Usmani, MD¹ and Alexander M. Lesokhin, MD¹⁴

¹Myeloma Service, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
²Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY
³Department of Pediatrics, Immune Discovery and Modeling Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁴Division of Myeloma, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁵Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY
⁶Myeloma Service, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York
⁷Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁸Transplant and Cellular Therapy Services, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY
⁹Transplant and Cellular Therapy Services, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁰Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York
¹¹Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
¹²University of Miami, Coral Gables, FL
¹³Sylvester Comprehensive Cancer Center, Miami, FL
¹⁴Myeloma & Cell Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY