-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

651A.O2.6 651. Multiple Myeloma and Plasma Cell Dyscrasias: Basic and Translational: Microenvironment and Immunity in Myeloma

Symposia: Multiple Myeloma and Plasma Cell Dyscrasias: Basic and Translational Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Fundamental Science, Adult, Clinical trials, Translational Research, Plasma Cell Disorders, Genomics, Clinical Research, Bioinformatics, Supportive Care, Diseases, Immune mechanism, Treatment Considerations, Immunology, Lymphoid Malignancies, Non-Biological therapies, Computational biology, Metabolism, Biological Processes, Microbiome, Molecular biology, Technology and Procedures, Multi-systemic interactions, Profiling, Study Population, Human, Pathogenesis, Animal model, Omics technologies
Sunday, December 8, 2024: 4:30 PM-6:00 PM
Pacific Ballroom Salons 24-26 (Marriott Marquis San Diego Marina)
Moderators:
Ross S Firestone, MD, PhD, Memorial Sloan Kettering Cancer Center and Michaela R Reagan, PhD, Maine Medical Center Research Institute
Disclosures:
No relevant conflicts of interest to declare.
4:30 PM

Heather Fairfield, MS1,2*, Haylee Duval1,3*, Kaitlyn Belknap1,4*, Katie Knox1,3*, Kehinde Abayomi1,5*, Sergey Ryzhov1,2,5* and Michaela R Reagan, PhD2,5,6

1Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME
2Tufts University School of Medicine, Boston, MA
3University of Southern Maine, Portland, ME
4University of New England College of Osteopathic Medicine, Biddeford, ME
5University of Maine Graduate School of Biomedical Sciences and Engineering, Orono, ME
6Center for Molecular Medicine, MaineHealth Institute for Research, South Portland, ME

4:45 PM

Sojeong Kim1*, Jeong-Eun Kwak1*, June-Young Koh2*, Hye Won Kook1*, Yu Ri Kim, MD1, Soo Jeong Kim, MD1*, Jin Seok Kim, MD, PhD3*, June-Won Cheong, MD, PhD4, Min Goo Lee1*, Hoyoung Lee5*, Eui-Cheol Shin5*, Kihyun Kim, MD6*, Haerim Chung, MD1*, Il-Kyu Choi7*, Jeong Seok Lee, MD, PhD5* and Hyunsoo Cho, MD, PhD8*

1Yonsei University College of Medicine, Seoul, Korea, Republic of (South)
2Inocras, San Diego
3Yonsei University College of Medicine, Severance Hospital, Seoul, Korea, Republic of (South)
4Division of Hematology, Department of Internal Medicine, Yonsei University College of Medicine, Severance Hospital, 50 Yonsei-ro, Seodaemun-gu, Seoul, Korea, Republic of (South)
5KAIST, Daejeon, Korea, Republic of (South)
6Sungkyunkwan University, Samsung Medical Center, Seoul, Korea, Republic of (South)
7DGIST, Daegu, Korea, Republic of (South)
8Yonsei University College of Medicine, Seoul, South Korea

5:00 PM

Kane A Foster, MSc1*, Elise Rees, PhD2*, Louise Ainley, BMBCh2*, Eileen M Boyle, MBChB, PhD3, Lydia Sarah Hui Lee, MD PhD4*, Gwennan Ward2*, Daria Galas-Filipowicz2*, Anna Mikolajczak5*, Emma J Lyon3*, Dylan Jankovic2*, Jasmine Rahman2*, Mahima Turakhia2*, Imran Uddin2*, Gordon Beattie6*, Yvette Hoade, BSc7*, Catherine Zhu2*, James L Reading2*, Ieuan Walker, MBBS, MSc, BSc, MRCP, FRCPath8, Michael A. Chapman, PhD8,9, Karthik Ramasamy, MD, PhD10, Javier Herrero, PhD2*, Benny Chain, PhD11*, Sergio A Quezada, PhD FMedSci12* and Kwee Yong, MD, PhD3

1Cancer Institute, University College London, London, ENG, United Kingdom
2Cancer Institute, University College London, London, United Kingdom
3UCL Cancer Institute, University College London, London, United Kingdom
4Research Department of Haematology, University College London, London, United Kingdom
5Department of Hematology, UCL Cancer Institute, London, United Kingdom
6UCL Cancer Institute, London, United Kingdom
7Haematology, Cancer Institute, University College London, London, United Kingdom
8MRC Toxicology Unit, University of Cambridge, Cambridge, United Kingdom
9Department of Haematology, University of Cambridge, Cambridge, United Kingdom
10Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
11Institute of Infection and Immunity, University College London, London, United Kingdom
12Research Department of Haematology, University College London Cancer Institute, London, United Kingdom., London, United Kingdom

5:15 PM

Marta Larrayoz, PhD1*, Elena Arriazu, PhD1*, Aintzane Zabaleta, PhD1*, Carmen Roncal, PhD1*, Ibon Tamayo, PhD2*, Diana Llopiz, PhD3*, Maddalen Jimenez, PhD1*, Carla Castro3*, Jon Celay, PhD1*, Carmen Vicente, PhD1*, Camila Guerrero, PhD1*, Sonia Sanz1*, Maria J Garcia-Barchino, PhD1*, Naroa Barrena1*, Noemi Puig, PhD4, Maria Teresa Cedena Romero, MD, PhD5*, Maria Jose Calasanz, PhD1*, Paula Rodríguez-Otero, MD, PhD1*, Jesús F. San-Miguel, MD, PhD1, Mikel Hernaez, PhD6*, Xabier Agirre, PhD1*, Pablo Sarobe, PhD3*, Felipe Prosper, MD, PhD1, Bruno Paiva, PhD1* and Jose A. Martinez-Climent, MD, PhD1

1Department of Hematology, Centre for Applied Medical Research, Cancer Center Clinica Universidad de Navarra, University of Navarra, IdiSNA, CIBERONC, Pamplona, Spain
2Computational Biology Program, Center for Applied Medical Research, Cancer Center Clinica Universidad de Navarra, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain, Pamplona, Spain
3Program of Immunology and Immunotherapy, Center for Applied Medical Research, Cancer Center Clinica Universidad de Navarra, IDISNA, CIBEREHD, Pamplona, Spain, Pamplona, Spain
4Hospital Universitario de Salamanca, Instituto de Investigacion Biomedica de Salamanca (IBSAL), University of Salamanca, Salamanca, Spain
5Department of Translational Hematology, Research Institute Hospital 12 de Octubre (i+12), Hematological Malignancies Clinical Research Unit H120-CNIO, CIBERONC, Madrid, Spain
6Computational Biology Program CIMA-Universidad de Navarra, Cancer Center Clinica Universidad de Navarra, IdISNA, Pamplona, Pamplona, Spain

5:30 PM

Urvi A. Shah, MD1,2, Laura Lucia Cogrossi, MS3,4*, Andriy Derkach, PhD5*, Francesca Castro, MS6*, Teng Fei, PhD7*, Susan DeWolf, MD8, Juan-Jose Garces, PhD9*, Anna Policastro, MS3,4*, Matteo Grioni3*, Sofia Sisti, MS4,10*, Blaslov Jenna11*, Peter Adintori, MS6*, Kinga K. Hosszu, PhD12*, Devin McAvoy12*, Mirae Baichoo, PhD13*, Justin Cross, PhD6*, Aishwarya Anuraj, MBBS14*, Charlotte Pohl, BA6*, Ruben Ramos, PhD6*, Jenny Paredes Sanchez, PhD15, Brianna Gipson6*, Kylee H Maclachlan, PhD, BSc, FRACP, FRCPA11, Ana Gradissimo, PhD6*, Leonardo Boiocchi, MD6*, Richard Koche, PhD16*, Ronan Chaligne, PhD17*, Torin Block, BA18*, Neha Korde, MD11, Carlyn Rose Tan, MD19, Malin Hultcrantz, MD11, Hani Hassoun, MD11, Gunjan L. Shah, MD20, Michael Scordo, MD21, Oscar B Lahoud, MD22, David J. Chung, MD, PhD20, Heather J. Landau, MD23, Jonathan U. Peled, MD, PhD24, Nicola Clementi4,10*, Marta Chesi, PhD25, P. Leif Bergsagel, MD26, Sham Mailankody, MD, MBBS11, Michael Pollak, MD27*, Anita D'Souza, MD28,29, Ola Landgren30, Susan Chimonas, PhD31*, Sergio Giralt, MD32,33,34, Saad Z. Usmani, MD11,32, Neil M. Iyengar, MD, BS, BA35*, Alexander M. Lesokhin, MD11,36, Matteo Bellone, MD37* and Marcel R.M. van den Brink, MD, PhD38

1Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
2MSKCC, New York, NY
3Cellular immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, Milano, Italy
4Vita-Salute San Raffaele University, Milano, Italy
5Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY
6Memorial Sloan Kettering Cancer Center, New York, NY
7Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY
8Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
9Memorial Sloan Kettering Cancer Center, New York
10Laboratory of Microbiology, IRCCS Ospedale San Raffaele, Milano, Italy
11Myeloma Service, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
12Department of Pediatrics, Immune Discovery and Modeling Service, Memorial Sloan Kettering Cancer Center, New York, NY
13Department of Immunology, Memorial Sloan Kettering Cancer Center, New York, NY
14Department of Medicine, Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, NY
15Beckham Research Institute, City of Hope, Los Angeles, CA
16Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY
17Single Cell Analytics and Innovation Lab, Memorial Sloan Kettering Cancer Center, New York, NY
18Nutritionquest, Berkeley, CA
19Myeloma Service, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Ardmore, PA
20Transplant and Cellular Therapy Services, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
21Transplant and Cellular Therapy Services, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY
22NYU Perlmutter Cancer Center, NYU Grossman School of Medicine, Brooklyn, NY
23Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
24Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, NY
25Mayo Clinic Arizona, Scottsdale, AZ
26Division of Hematology/Oncology, Mayo Clinic, Phoenix, AZ
27McGill University, Montreal, QC, CAN
28Center for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI
29Medical College of Wisconsin, Milwaukee, WI
30Sylvester Comprehensive Cancer Center, Miami, FL
31Center for Health Policy and Outcomes, Memorial Sloan Kettering Cancer Center, New York, NY
32Department of Medicine, Weill Cornell Medical College, New York, NY
33Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York
34Weill Cornell Medical College, Memorial Sloan Kettering Cancer Center, New York, NY
35Memorial Sloan-Ketter Cancer Ctr/NY Presb Hosp (Cornell), New York, NY
36Myeloma & Cell Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
37Cellular Immunology Unit, Division of Immunology, Infectious Diseases and Transplantation, IRCCS Ospedale San Raffaele, Milan, Italy
38Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA

5:45 PM

Ross S Firestone, MD, PhD1, Anish Kumar Simhal, PhD2, Devin McAvoy3*, Eric M Jurgens, MD1, Juan-José Garcés, PhD4*, David Nemirovsky5*, Andriy Derkach, PhD5*, Kylee H Maclachlan, PhD, BSc, FRACP, FRCPA1, Malin Hultcrantz, MD1, Sham Mailankody, MD, MBBS1, Urvi A. Shah, MD1, Carlyn Rose Tan, MD1, Neha Korde, MD1, Hani Hassoun, MD1, Sridevi Rajeeve, MD1, Hamza Sloan Hashmi, MD1*, Heather J. Landau, MD6, Michael Scordo, MD7, Gunjan L. Shah, MD8, Sergio Giralt, MD9, Benjamin Diamond, MD10, Francesco Maura, MD11, Kinga K. Hosszu, PhD3*, David J. Chung, MD, PhD8, Ola Landgren12, Saad Z. Usmani, MD1 and Alexander M. Lesokhin, MD13

1Myeloma Service, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
2Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY
3Department of Pediatrics, Immune Discovery and Modeling Service, Memorial Sloan Kettering Cancer Center, New York, NY
4Division of Myeloma, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
5Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY
6Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
7Transplant and Cellular Therapy Services, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY
8Transplant and Cellular Therapy Services, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
9Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York
10Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
11University of Miami, Coral Gables, FL
12Sylvester Comprehensive Cancer Center, Miami, FL
13Myeloma & Cell Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY

*signifies non-member of ASH