-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

654.O1.6 654. Multiple Myeloma: Pharmacologic Therapies: Optimizing Therapy in Newly Diagnosed Myeloma and Beyond

Symposia: Multiple Myeloma: Pharmacologic Therapies Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Clinical trials, Adult, Combination therapy, Clinical Research, Plasma Cell Disorders, Diseases, Therapy sequence, Immunotherapy, Biological therapies, Treatment Considerations, Lymphoid Malignancies, Monoclonal Antibody Therapy, Study Population, Human, Measurable Residual Disease
Sunday, December 8, 2024: 4:30 PM-6:00 PM
Pacific Ballroom Salons 21-22 (Marriott Marquis San Diego Marina)
Moderators:
Prashant Kapoor, MD, Mayo Clinic and Monique A. Hartley-Brown, MD, Dana-Farber Cancer Institute, Harvard Medical School
Disclosures:
Kapoor: Amgen: Research Funding; Regeneron: Research Funding; Bristol Myers Squibb: Research Funding; Loxo Pharmaceuticals: Research Funding; Ichnos: Research Funding; Karyopharm: Research Funding; Sanofi: Membership on an entity's Board of Directors or advisory committees, Research Funding; AbbVie: Membership on an entity's Board of Directors or advisory committees, Research Funding; GlaxoSmithKline: Membership on an entity's Board of Directors or advisory committees, Research Funding; BeiGene: Membership on an entity's Board of Directors or advisory committees, Research Funding; Mustang Bio: Membership on an entity's Board of Directors or advisory committees; Janssen: Membership on an entity's Board of Directors or advisory committees; Pharmacyclics: Membership on an entity's Board of Directors or advisory committees; X4 Pharmaceuticals: Membership on an entity's Board of Directors or advisory committees; Kite: Membership on an entity's Board of Directors or advisory committees; Oncopeptides: Membership on an entity's Board of Directors or advisory committees; Angitia Bio: Membership on an entity's Board of Directors or advisory committees; CVS Caremark: Consultancy; Keosys: Consultancy. Hartley-Brown: Bristol Myers Squibb/Celgene: Consultancy, Honoraria, Research Funding; Janssen: Consultancy, Honoraria, Research Funding; Sanofi: Consultancy, Honoraria, Research Funding; GSK: Consultancy, Honoraria, Research Funding; AbbVie: Consultancy, Honoraria, Research Funding; Karyopharm: Consultancy, Honoraria, Research Funding; Multiple Myeloma Research Foundation: Consultancy, Honoraria, Research Funding; Cancer Care: Consultancy, Honoraria.
4:30 PM

Gordon Cook, PhD, DSc1,2*, Charlotte Pawlyn, PhD3, Kara-Louise Royle4*, Ethan R Senior5*, Dax Everritt6*, Jenny Bird7*, Stella Bowcock8*, Bryony Dawkins, MSc9*, Mark Drayson10*, Sharon Gillson, BSc5*, Catherine Olivier1*, Matthew W. Jenner11*, John Jones12*, Martin F Kaiser, MD13, Bhuvan Kishore14*, David Meads, PhD9*, Neil Rabin15*, Roger G Owen, MD, MRCP, FRCPath16*, Ruth M de Tute, MSc, PhD, FRCPath16*, Christopher Parrish, MBBChir, MRCP, FRCPath, MA, PhD4, Alan Chant17*, David A. Cairns, PhD4* and Graham Jackson, MD18*

1Leeds Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, United Kingdom
2CRUK Clinical Trials Unit, Leeds Institute of Clinical Tial Research, Leeds Myeloma Research Group and NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom
3Institute of Cancer Research, Sutton, United Kingdom
4Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, United Kingdom
5Leeds Institute of Clinical Trials Research, Cancer Research UK Clinical Trials Unit, Leeds, United Kingdom
6CRUK CTU, Leeds Insitute of Clinical Trial Research, University of Leeds, Leeds, United Kingdom
7Department of Haematology, University Hospitals Bristol NHS Foundation Trust, Cambridge, GBR
8King’s College Hospital, London, United Kingdom
9University of Leeds, Academic Unit of Health Economics, Leeds, United Kingdom
10University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom
11University Hospital Southampton, Southampton, United Kingdom
12East Sussex Healthcare NHS Trust, London, United Kingdom
13The Institute of Cancer Research, London, ENG, United Kingdom
14Heartofengland NHS FT, Birmingham, GBR
15Department of Haematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom
16HMDS, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
17Patient and Public Contributor, NA, United Kingdom
18University of Newcastle, Department of Haematology, Newcastle, United Kingdom

4:45 PM

Pieter Sonneveld, MD1, Meletios A. Dimopoulos, MD2, Meral Beksac, MD3,4, Bronno van der Holt, PhD1,5*, Francesca Gay, MD, PhD6*, Heinz Ludwig, MD7, Sonja Zweegman, MD, PhD8, Vladimir Maisnar, MD, PhD9*, Maria Teresa Petrucci, MD10*, Paolo Corradini, MD11, Francesca Patriarca, MD, PhD12*, Angelo Belotti, MD13*, Micol Quaresima, MD14*, Mariella Grasso, MD15*, Massimo Offidani, MD16*, Laura Paris, MD17*, Anna Marina Liberati, MD18, Markus Hansson, MD, PhD19*, Heleen Visser-Wisselaar, PhD5*, Giulia Fumero, MSc20*, Renato Zambello, MD21*, Paula F Ypma, MD, PhD22*, Anna Pascarella, MD23*, Niels Frost Andersen, MD, PhD24*, Alexandra Croockewit, MD, PhD25*, Mario Boccadoro, MD20 and Michele Cavo, MD26,27*

1Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands
2Hematology and Medical Oncology, Department of Clinical Therapeutics, National and Kapodistrian University of Athens School of Medicine, Athens, Greece
3Department of Hematology, Ankara University Faculty of Medicine, Ankara, Turkey
4Department of Hematology, Ankara Liv Hospital, Istinye University, Ankara, Turkey
5HOVON Foundation, Rotterdam, Netherlands
6Division of Hematology, AOU Città della Salute e della Scienza di Torino, University of Torino and Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy
7Wilhelminen Cancer Research Institute, c/o Department of Medicine I, Clinic Ottakring, Vienna, Austria
8Department of Hematology, Amsterdam UMC, Cancer Center Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
94th Department of Medicine - Haematology, Charles University Hospital and Faculty of Medicine Hradec Kralove, Hradec Kralove, Czech Republic
10Hematology, Department of Translational and Precision Medicine, Azienda Ospedaliera Policlinico Umberto I, Sapienza University of Rome, Rome, Italy
11Fondazione IRCCS Istituto Nazionale dei Tumori Milano, Università di Milano, Milano, Italy
12Hematologic Clinic and Transplant Center, University Hospital of Central Friuli, DMED, University of Udine, Udine, Italy
13Department of Hematology, ASST Spedali Civili di Brescia, Brescia, Italy
14Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy
15Azienda Ospedaliera S. Croce e Carle, Cuneo, Italy
16AOU delle Marche, Ancona, Italy
17Division of Hematology, ASST Papa Giovanni XXIII, Bergamo, Italy
18A.O. Santa Maria di Terni – Università degli Studi di Perugia, Terni–Perugia, Italy
19Department of Hematology, Skåne University Hospital, Lund, Sweden
20European Myeloma Network, EMN, Italy
21Department of Medicine (DIMED), Hematology and Clinical Immunology, Padua University, Padua, Italy
22Department of Hematology, HagaZiekenhuis, Den Haag, Netherlands
23UOC Ematologia, Ospedale dell'angelo, Venezia Mestre, Italy
24Department of Haematology, Aarhus University Hospital, Aarhus, Denmark
25Department of Hematology, Radboud University Medical Centre, Nijmegen, Netherlands
26IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia “Seràgnoli”, Bologna, Italy
27Dipartimento di Scienze Mediche e Chirurgiche, Università di Bologna, Bologna, Italy

5:00 PM

Laahn Foster, MD1*, Larry D Anderson Jr., MD, PhD2, Alfred Chung, MD3, Chakra Chaulagain, MD4, Erin M. Pettijohn, MD5, Andrew J. Cowan, MD6*, Caitlin Costello, MD7, Sarah M. Larson, MD8, Douglas W. Sborov, MD, MS9, Kenneth H. Shain, MD, PhD10, Rebecca Silbermann11, Peter M. Voorhees, MD12, Maria Krevvata, PhD13*, Huiling Pei, PhD14*, Sharmila Patel, PhD15*, Vipin Khare, MD15*, Annelore Cortoos, MD15*, Robin Carson, MD13, Thomas S. Lin, MD, PhD15 and Ashraf Z. Badros, MD, Ch.B.16

1Division of Hematology Oncology, University of Virginia, Charlottesville, VA
2Myeloma, Waldenstrom’s, and Amyloidosis Program, Hematologic Malignancies and Cellular Therapy Program, Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX
3Department of Medicine, University of California San Francisco, San Francisco, CA
4Department of Hematology and Oncology, Myeloma and Amyloidosis Program, Cleveland Clinic Florida, Weston, FL
5Cancer and Hematology Centers of Western Michigan, Grand Rapids, MI
6Division of Medical Oncology, Fred Hutch Cancer Center/University of Washington, Seattle, WA
7Moores Cancer Center at University of California San Diego, La Jolla, CA
8Division of Hematology and Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA
9Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
10Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL
11Knight Cancer Institute, Oregon Health & Science University, Portland, OR
12Levine Cancer Institute, Atrium Health Wake Forest University School of Medicine, Charlotte, NC
13Janssen Research & Development, LLC, Spring House, PA
14Janssen Research & Development, LLC, Titusville, NJ
15Janssen Scientific Affairs, LLC, a Johnson & Johnson company, Horsham, PA
16Greenbaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD

5:15 PM

Annemiek Broijl, PhD1, Fredrik Schjesvold, MD, PhD2,3, Abdel el Yaakoubi, MSc4*, Djamila Issa, MD PhD5*, Sonja Zweegman, MD, PhD6, Kon-Siong Jie7*, Mario Boccadoro, MD8, Roman Hajek9, Bronno van der Holt, PhD4*, Ruth Wester, MD, PhD10* and Pieter Sonneveld, MD11

1Erasmus MC Cancer Institute, Rotterdam, Netherlands
2KG Jebsen Center for B Cell Malignancies, University of Oslo, Oslo, Norway
3Oslo Myeloma Center, Department of Hematology, Oslo University Hospital, Oslo, Norway
4HOVON Foundation, Rotterdam, Netherlands
5Department of Internal Medicine, Jeroen Bosch Hospital, Den Bosch, Netherlands
6Amsterdam UMC, Department of Hematology, Netherlands, Amsterdam, Netherlands
7Zuyderland Medical Centre, Sittard-Geleen, Netherlands
8-, Torino, TO, Italy
9Department of Haematooncology, University Hospital Ostrava, Ostrava, Czech Republic
10Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands
11Erasmus MC Cancer Institute, Rotterdam, Zuid-Holland, Netherlands

5:30 PM

Luciano J. Costa, MD, PhD1, Fredrik Schjesvold, MD, PhD2,3, Rakesh Popat, MBBS, PhD4, David Siegel5*, Saad Z. Usmani, MD6, Syed Abbas Ali7, Michael P. Chu, MD8, Monique A. Hartley-Brown, MD9, Nizar J. Bahlis10*, Albert Oriol11*, Joaquín Martínez Lopez12*, Enrique M. Ocio13, Karthik Ramasamy14, Donna Reece, MD15, Emma Searle16*, Allison Gaudy17*, Antonina Kurtova17*, Wen Zhang17*, Rafael Sarmiento18*, August Dietrich19, Jessica Katz17, Michael Pourdehnad, MD17 and Paul G. Richardson9

1Division of Hematology and Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL
2Oslo Myeloma Center, Department of Hematology, Oslo University Hospital, Oslo, Norway
3Department of Haematology, Oslo Myeloma Center, Oslo University Hospital, and KG Jebsen Center for B Cell Malignancies, University of Oslo, Oslo, Norway
4NIHR UCLH Clinical Research Facility, University College London Hospitals NHS Foundation Trust, London, United Kingdom
5John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ
6Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
7Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD
8Department of Oncology, University of Alberta, Edmonton, AB, Canada
9Dana-Farber Cancer Institute, Boston, MA
10Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada
11Catalan Institute of Oncology and Josep Carreras Institute, Hospital Germans Trias i Pujol, Badalona, Spain
12Department of Hematology, Hospital 12 de Octubre, Complutense University, H12O-CNIO Clinical Research Unit, CIBERONC, Madrid, Spain
13Hospital Universitario Marqués de Valdecilla (IDIVAL), Universidad de Cantabria, Santander, Spain
14Department of Clinical Haematology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
15Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON, Canada
16The Christie NHS Foundation Trust and University of Manchester, Manchester, United Kingdom
17Bristol Myers Squibb, Princeton, NJ
18Bristol Myers Squibb, Center for Innovation and Translational Research Europe (CITRE), Seville, Spain
19Research and Development, Bristol Myers Squibb, Princeton, NJ

5:45 PM

Maria- Victoria Mateos1, Bruno Paiva, PhD2*, Maria Teresa Cedena Romero, MD, PhD3*, Noemi Puig, PhD4, Anna Sureda Balari5, Albert Oriol, MD, PhD6*, Enrique M Ocio, MD, PhD7*, Laura Rosiñol, MD, PhD8*, Yolanda González-Montes, MD, PhD9*, Joan Bargay, MD, PhD10*, Esther Gonzalez Garcia, MD, PhD11*, Miguel Teodoro Hernández Garcia, MD, PhD12*, Angel Ramirez, MD, PhD13*, Alexia Suarez-Cabrera, MD, PhD14*, María-Jesús Blanchard, MD, PhD15*, Sebastián Garzón, MD, PhD16*, Luis Felipe Casado17*, Valentin Cabanas Perianes, MD, PhD18*, Jaime Perez de Oteyza19*, Mercedes Gironella, MD20*, Joaquin Martínez-López21*, Ana-Isabel -Teruel, MD, PhD22*, Pilar Delgado, MD, PhD23*, Elena Prieto, MD, PhD24*, Juan-Jose Lahuerta Palacios, MD, PhD25*, Joan Bladé, MD, PhD26* and Jesús F. San-Miguel, MD, PhD27

1Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Centro de Investigación del Cáncer (IBMCC-USAL,CSIC), Salamanca, Spain
2Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), IDISNA, CIBER-ONC number CB16/12/00369 and CB16/12/00489, Pamplona, Spain
3Instituto de Investigación IMAS12, Madrid, Spain
4Hospital Universitario de Salamanca (HUSAL), IBSAL, IBMCC (USAL-CSIC), CIBERONC, Salamanca, Spain
5Clinical Hematology Department, Institut Català d’Oncologia-Hospitalet, IDIBELL, Barcelona, Spain
6Hematology, Catalan Institute of Oncology and Josep Carreras Institute, Hospital Germans Trias i Pujol, Badalona, Spain
7Hospital Universitario Marqués de Valdecilla (IDIVAL), Universidad de Cantabria, Santander, Spain
8Hematology, IDIBAPS, Hospital Clinic, Barcelona, ESP
9Hematology, Institut d'Oncologia Dr. Josep Trueta, Girona, Spain
10Hematology, Hospital Universitari Son Llàtzer, IdIsBa, Palma de Mallorca, Spain
11Hematology, University Hospital Cabueñes, Gijón, Spain
12Hematology, Hospital Universitario de Canarias, Santa cruz de Tenerife, Spain
13Hematology, Hospital Central de Asturias, Oviedo, Spain
14Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas De Gran Canaria, Spain
15Hematology, Hospital Universitario Ramon y Cajal, Madrid, Spain
16Hematology, Hospital Universitario Jerez de la Frontera, Jerez de la Frontera, Cádiz, Spain
17Hematology, Hospital General Universitario de Toledo, Toledo, Spain
18Hematology, IMIB-Virgen de la Arrixaca University Hospital, University of Murcia, El Palmar, Murcia, Spain
19Clinical Hematology and Oncohematology, Hospital Universitario HM Sanchinarro, Madrid, Spain
20Hematology, Hospital Universitari Vall d'Hebron, Barcelona, Spain
21Department of Hematology, Hospital Universitario 12 de Octubre, Madrid, Spain
22Hematology, Hospital Clínico Universitario de Valencia, Valencia, Spain
23Hematology Department, Hospital Universitario Miguel Servet, Zaragoza, Spain
24Hematology Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain
25Hematology, Hospital Universitario 12 de Octubre, Imas12, CIBERONC, Madrid, Spain
26Hematology, Hospital Clínic de Barcelona, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona; and GEM/PETHEMA, Barcelona, Spain
27Department of Hematology, Centre for Applied Medical Research, Cancer Center Clinica Universidad de Navarra, University of Navarra, IdiSNA, CIBERONC, Pamplona, Spain

*signifies non-member of ASH