Maiko Sezaki, PhD^1*, Asumi Yokota, PhD^2*, Xuan Zhang, PhD^3*, Mingzhe Pan^1*, Zhihong Wang, MD^4*, Michihiro Hashimoto, PhD^1*, Zohra Nooruddin, MD⁵, Eric M. Pietras, PhD⁶, Nathan Salomonis, PhD^7*, H. Leighton Grimes, PhD⁸ and Gang Huang, PhD^1,9

¹Department of Cell Systems and Anatomy, UT Health San Antonio, San Antonio, TX
²Laboratory of Stem Cell Regulation, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
³Division of Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
⁴Department of Hematology, Fujian Provincial Hospital, Fuzhou, China
⁵Division of Hematology and Medical Oncology, UT Health San Antonio MD Anderson Cancer Center, San Antonio, TX
⁶Division of Hematology, Department of Medicine, University of Colorado, Aurora, CO
⁷Division of Biomedical Informatics, Cincinnati Children's Hospital, Cincinnati, OH
⁸Division of Immunobiology, Cincinnati Children's Hospital, Cincinnati, OH
⁹Department of Pathology and Laboratory Medicine, UT Health San Antonio, San Antonio, TX

Srinivas Aluri, PhD¹, Kimo Bachiashvili², Anjali Budhathoki^3*, Jong J Jeong^4*, Shanisha Gordon Mitchell^5*, Milagros Carbajal^6*, Samarpana Chakraborty¹, Sanjay Pandey, PhD^5*, Mahinder Paul Wadhwa^5*, Srabani Sahu, MS^6*, Jung-In Yang, MD^7*, Gaurav S Choudhary, PhD^8*, Tushar Damodar Bhagat, PhD, MSc, MS^8*, Nandini Ramachandra, MS^9*, Rongbao Zhao, PhD^9*, Bianca Rivera, PhD^6*, Ritesh Aggarwal, PhD^9*, Kith Pradhan, PhD^10*, Shahina Maqbool^5*, Seong jin Kim^11*, Sunjin Hwang^11*, Ulrich Steidl¹², Aditi Shastri, MD¹³, Marc Raaijmakers, MD¹⁴, Andrea Pellagatti, PhD^15*, Jacqueline Boultwood, PhD^16*, Amittha Wickrema^17* and Amit Verma, MD^18,19

¹Department of Oncology, Albert Einstein College of Medicine, New York, NY
²O’Neal Comprehensive Cancer Center at the University of Alabama at Birmingham, Birmingham, AL
³Montefiore Medical Centre, Bronx, NY
⁴Univeristy of Chicago, Chicago, IL
⁵Albert Einstein College of Medicine, Bronx
⁶Blood Cancer Institute, Department of Oncology, Albert Einstein College of Medicine, Bronx, NY
⁷Cold Springer Harbor Laboratory, Cold Spring Harbor, NY
⁸Albert Einstein College of Medicine, Bronx, NY
⁹Montefiore Einstein Cancer Center, Blood Cancer Institute, Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY
¹⁰Department of Oncology, Blood Cancer Institute, Albert Einstein College of Medicine, Bronx, NY
¹¹Medpacto, Seoul, Korea, Republic of (South)
¹²Department of Oncology, Montefiore Medical Center, Bronx, NY
¹³Blood Cancer Institute, Department of Oncology, University of Vermont, Bronx, NY
¹⁴Erasmus MC Cancer Institute, Rotterdam, Netherlands
¹⁵University of Oxford, Oxford, United Kingdom
¹⁶Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
¹⁷University of Chicago, Chicago, IL
¹⁸Department of Medical Oncology, Albert Einstein College of Medicine, Bronx, NY
¹⁹Hematology/Oncology, Montefiore Medical Center/ Albert Einstein College of Medicine, Bronx, NY

Aintzane Diaz-Mazkiaran, MSc^1,2,3*, Jesús de la Fuente^4*, Guillermo Serrano, PhD^1,4*, Paula Garcia-Olloqui^2,3*, Nerea Berastegui^2,3*, Marina Ainciburu, MSc^2,3*, Ana Alfonso Pierola, MD, PhD^2,5*, Amaia Vilas-Zornoza^2,3*, Patxi San-Martin^3*, Jose Maria Lamo-Espinosa, MD^6*, Mikel San-Julian^6*, Pamela Acha^7,8*, Tamara Jimenez^2,9*, Antonieta Molero^8*, Maria Julia Montoro, MD, PhD^8*, Francesc Sole, PhD⁷, Maria Diez-Campelo, MD, PhD^2,9*, David Valcarcel, MD, PhD⁸, Irene Ganan-Gomez, PhD, MSc^2,3*, Felipe Prosper, MD, PhD^2,3,5, Mikel Hernaez, PhD^1,2,10* and Teresa Ezponda^2,3*

¹Computational Biology Program CIMA-Universidad de Navarra, Cancer Center Clínica Universidad de Navarra (CCUN), IdISNA, Pamplona, Spain
²Centro de Investigación Biomédica en Red de Cáncer, CIBERONC, Madrid, Spain
³Hematology-Oncology Program, CIMA, Cancer Center Clínica Universidad de Navarra (CCUN), IdiSNA, Pamplona, Spain
⁴Department of Electrical and Electronics engineering, School of Engineering (Tecnun), University of Navarra, Donostia, Spain
⁵Hematology and Cell Therapy Service, Cancer Center Clínica Universidad de Navarra (CCUN), IdISNA, Pamplona, Spain
⁶Department of Orthopedics, Clínica Universidad de Navarra, Pamplona, Spain
⁷MDS Research Group, Josep Carreras Leukaemia Research Institut, Universitat Autònoma de Barcelona, Barcelona, Spain
⁸Service of Hematology, Hospital Universitari Vall d’Hebron, Barcelona; Vall d’Hebron Instituto de Oncología (VHIO), Barcelona, Spain
⁹Department of Hematology, Hospital Universitario de Salamanca-IBSAL, Salamanca, Spain
¹⁰Instituto de Ciencia de los Datos e Inteligencia Artificial (DATAI), University of Navarra, Pamplona, Spain

Nathan J Hull^1*, Rachel Cant^2*, Yu-Hung Wang, MD^2*, Kristian Gurashi, PhD^3*, Laura A Guest, PhD^2*, Daniel H Wiseman, MB ChB PhD MRCP FRCPath^4* and Kiran Batta, PhD²

¹Division of Cancer Sciences, University of Manchester, Manchester, ENG, United Kingdom
²Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom
³University of Oxford, Oxford, United Kingdom
⁴The Christie NHS Foundation Trust, Manchester, United Kingdom

Lukas Kazianka^1*, Michaela Prchal-Murphy^2*, Christiane Agreiter, MSc^1*, Carmen Schweicker, MSc^1*, Maurizio Forte, MSc^1*, Emiel van der Kouwe, PharmD, PhD^1*, Christoph Kornauth, MD^3*, Alexander Pichler, MD^1*, Tea Pemovska, PhD^1*, Johannes Rohrbeck, MD^3*, Margit Schmeidl^3*, Selina Troester, MSc^4*, Julia List^2*, Veronika Sexl, MD, PhD^2*, Florian Grebien, MSc, PhD^4*, Peter Valent, MD¹, Daniel G. Tenen, MD^5* and Philipp Bernhard Staber, MD, PhD¹

¹Department of Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria
²Department for Biological Sciences and Pathobiology, University of Veterinary Medicine, Vienna, Austria
³Department of Pathology, Medical University of Vienna, Vienna, Austria
⁴Department of Medical Biochemistry, University of Veterinary Medicine, Vienna, Austria
⁵Hematology/Oncology, Beth Israel Deaconess Medical Center, Boston, MA

Rasoul Pourebrahim, MD, PhD¹, Dexin Yang^2*, Priyanka Khanna, BSc^3*, Muharrem Muftuoglu, MD⁴, Lauren B. Ostermann, BSc^4*, Shayaun Khazaei, BSc^3*, Ran Zhao, MSc^4*, Mihai Gagea, DVM^5*, Simona Colla, PhD⁶, Guillermo Garcia-Manero, MD⁷, Ruoyan Li, PhD^2*, Michael Andreeff, MD, PhD⁴ and Koichi Takahashi, MD, PhD^7,8

¹Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Missouri City, TX
²Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston
³Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston
⁴Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Department of Veterinary Medicine & Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
⁶Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston
⁷Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁸Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX