Sankalp Arora, MBBS¹, Musa Yilmaz, MD^2*, Wei-Ying Jen, MD, FRCPath, MA^2*, Nicholas J. Short, MD², Sanam Loghavi, MD³, Tapan M. Kadia, MD², Courtney D. DiNardo, MD, MSc⁴, Gautam Borthakur, MD⁵, Indraneel Deshmukh, MBBS, MPH^6*, Ghayas C. Issa, MD², Joseph E. Jabbour^7*, Naveen Pemmaraju, MD², Michael Andreeff, MD, PhD⁵, Koichi Takahashi, MD, PhD⁸, Kapil N. Bhalla, MD⁶, Hussein A. Abbas, MD, PhD², Guillermo Garcia-Manero, MD², Farhad Ravandi, MBBS⁹, Hagop M. Kantarjian, MD² and Naval Daver, MD¹⁰

¹Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
⁵Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁶UT MD Anderson Cancer Center, Houston, TX
⁷Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
⁸Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
⁹Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX
¹⁰MD Anderson Cancer Center, Houston, TX

Vikram Dhillon, DO, MBA^1,2*, Jeff Aguilar, MD, MBA^3*, Paul Kim, BA^4*, Dakshin Padmanabhan, MBBS⁵, Jay Yang, MD⁶, Gregory Dyson, PhD^7*, David Carr, MD^6*, Jaroslaw Maciejewski⁸ and Suresh Kumar Balasubramanian, MD^9,10

¹Department of Oncology, Karmanos Cancer Center/Wayne State University, Detroit, MI
²Department of Hematology/Oncology, Neal Cancer Center/Houston Methodist Hospital, Houston, TX
³Department of Oncology, Karmanos Cancer Institute/Wayne State University, Windsor, ON, Canada
⁴Karmanos Cancer Institute/Wayne State University, Detroit, MI
⁵Internal Medicine, Trinity Health Oakland Hospital, Rochester Hills, MI
⁶Department of Oncology, Karmanos Cancer Institute/Wayne State University, Detroit, MI
⁷Karmanos Cancer Institute/Department of Oncology, Wayne State University, Detroit, MI
⁸Taussig Cancer Center, Cleveland, OH
⁹Department of Oncology, Karmanos Cancer Institute/Wayne State University, Troy, MI
¹⁰Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH

Yibo Wu, MD^1,2,3*, Xiaolin Yuan, MD^1,2,3*, Xiaoyu Lai, MD^4*, Lizhen Liu, MD^5*, Jimin Shi^1*, Weiyan Zheng, MD^4*, Jian Yu, MD^1*, Yanmin Zhao, MD^5*, Jie Sun, PhD^6*, Xiujin Ye^1*, Zhen Cai^1*, He Huang, MD^1*, Shanshan Pei, PhD^1* and Yi Luo^3,5,7

¹Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, hangzhou, China
²Zhejiang Province Engineering Research Center for Stem Cell and Immunity Therapy, hangzhou, China
³Institute of Hematology, Zhejiang University, hangzhou, China
⁴Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, Hangzhou, China
⁵Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⁶Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
⁷Zhejiang Province Engineering Research Center for Stem Cell and Immunity Therapy, Hangzhou, China

Rabea Mecklenbrauck, MD^1,2*, Angela Villaverde Ramiro^3*, Eric Sträng, PhD^4*, Razif Gabdoulline^1*, Javier Martínez Elicegui^3*, Marta Sobas, MD^5*, Lisa Pleyer, MD^6*, Maria Teresa Voso, MD⁷, Axel Benner^8*, Alberto Hernández Sánchez, MD^9*, Jesse M. Tettero, MD, PhD^10*, Laura Tur^11*, Klaus H Metzeler, MD¹², Guadalupe Onate, MD, PhD^13*, Soren Lehmann, MD, PhD^14*, Brian J P Huntly, MD^15*, Ian Thomas^16*, Felicitas R Thol, MD¹, Florian Heidel, MD¹, Peter J. M. Valk, PhD¹⁷, Konstanze Döhner, MD¹⁸, Torsten Haferlach, MD¹⁹, Ken I Mills, PhD, FRCPath²⁰, Hartmut Döhner, MD¹⁸, Gastone Castellani, PhD^21*, Gert Ossenkoppele, MD^10*, Jesus Maria Hernandez Rivas, MD⁹, Lars Bullinger⁴ and Michael Heuser, MD^1,22

¹Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
²MRC Molecular Haematology Unit, Radcliffe Department of Medicine, Weatherall Institute of Medicine, University of Oxford, Oxford, United Kingdom
³Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain
⁴Department of Hematology, Oncology, Tumor Immunology, Charité University Medicine, Berlin, Germany
⁵Department of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Medical University of Wroclaw, Wroclaw, Poland
⁶3rd Medical Dept. with Haematology, Medical Oncology, Haemostaseology, Rheumatology and Infectiology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria
⁷Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
⁸Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany
⁹Hematology Department, Hospital Universitario de Salamanca (CAUSA/IBSAL), Salamanca, Spain
¹⁰Department of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, Netherlands
¹¹GMV Innovating Solutions, Valencia, Spain
¹²Department for Hematology, Cell Therapy, Hemostaseology and Infectious Diseases, University of Leipzig Medical Center, Leipzig, Germany
¹³Hematology Department, Hospital Santa Creu i Sant Pau, Barcelona, Spain
¹⁴Center for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institute, Stockholm, Sweden
¹⁵Department of Haematology and Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom
¹⁶Centre for Trials Research, Cardiff University, Cardiff, United Kingdom
¹⁷Erasmus University Medical Center, Rotterdam, Netherlands
¹⁸Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
¹⁹MLL Munich Leukemia Laboratory, Munich, Germany
²⁰Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, NI, United Kingdom
²¹Dipartimento di Scienze Mediche e Chirurgiche, Università di Bologna, Bologna, Italy
²²Department of Internal Medicine IV, University Hospital Halle (Saale), Halle (Saale), Germany

Jad Othman, FRACP, FRCPA, MBBS^1,2, Nicola Potter, PhD^2*, Sylvie D Freeman³, Nicholas McCarthy^4*, Jelena Jovanovic, PhD^5*, Manohursingh Runglall^6*, Joanna Canham^7*, Ian Thomas^8*, Sean Johnson^9*, Jamie Cavenagh^10*, Panagiotis Kottaridis, FRCPath, PhD, MSc^11*, David Taussig, PhD, MRCP, FRCPath¹², Claire Arnold^13*, Claire Hemmaway^14*, Dominic J. Culligan, MD, FRCP, FRCPath, BSc, MBBS^15*, Ulrik Malthe Overgaard^16*, Alan K. Burnett, MD^17*, Mike Dennis, MD, MRCP, FRCPath¹⁸, Richard Dillon, MA^19,20 and Nigel H. Russell, MD¹

¹Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom
²Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
³University of Birmingham, Birmingham, United Kingdom
⁴University of Birmingham, UK, Birmingham, GBR
⁵King’s College London, London, United Kingdom
⁶King's College, London, London, GBR
⁷Cardiff University, Cardiff, WAL, GBR
⁸Centre for Trials Research, Cardiff University, Cardiff, United Kingdom
⁹Cardiff University, Cardiff, United Kingdom
¹⁰St. Bartholomew's Hospital London, London, United Kingdom
¹¹University College London Hospitals, London, United Kingdom
¹²The Royal Marsden Hospital and Institute of Cancer Research, London, United Kingdom
¹³Belfast City Hospital, Belfast, United Kingdom
¹⁴Auckland City Hospital, Auckland, NZL
¹⁵Aberdeen Royal Infirmary, NHS Grampian, Aberdeen, United Kingdom
¹⁶Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
¹⁷Paul O’Gorman Leukaemia Centre, Glasgow University, Glasgow, United Kingdom
¹⁸The Christie NHS Foundation Trust, Manchester, United Kingdom
¹⁹Guy's and St. Thomas' NHS Foundation Trust, London, ENG, United Kingdom
²⁰Department of Medical and Molecular Genetics, King's College, London, United Kingdom

Mael Heiblig^1*, Gaspar Aspas Requena^2*, Urbain Tauveron-Jalenques^2*, Emmanuelle Tavernier, MD^3*, Jérome Cornillon, MD^4*, Martin Carre, MD^5*, Mathieu Meunier^6*, Ugo Thévenet, MD^7*, Boullanger Fow Heng Nadine^8*, Clémence Santana^9*, Clément Rocher, MD^10*, Sylvain Lamure, MD, PhD^11*, Amine Belhabri, MD^12*, Mauricette Michallet, MD, PhD¹², Adrien Contejean^13*, Natacha Mauz^13*, Gian Matteo Pica, MD^14*, Arthur Dony^14* and Zofia Gross, MD^15*

¹Service d'hématologie clinique, Hospices Civils de Lyon, Hôpital Lyon Sud, Pierre-Bénite, France
²Département d'Hématologie, CHU de Clermont-Ferrand, Clermont-Ferrand, France
³Institut De Cancérologie De La Loire, Saint Priest En Jarez, FRA
⁴Institut Cancerologique De La Loire, Saint-priest-en-Jarez, FRA
⁵Clinical Hematology Department, CHU Grenoble Alpes - Université Grenoble Alpes, Grenoble, France
⁶Department of Hematology CHU Grenoble Alpes, Grenoble, France
⁷CH de Roanne, Roanne, France
⁸Département d'hématologe, CH Roanne, Roanne, France
⁹Département d'Hématologie, CH de Valence, Valence, France
¹⁰Département d'Hématologie, Centre Hospitalier Bourgoin Jallieu, Bourgoin Jallieu, France
¹¹Département d'Onco-Hématologie, Hôpitaux Nord-Ouest, Villefranche-sur-Saone, France
¹²Département de Cancérologie médicale, Centre Léon Bérard, Lyon, France
¹³Département d'Hématologie, Centre Hospitalier Annecy Genevois, Epagny Metz-Tessy, France
¹⁴Département d'Hématologie, CH Chambery, Chambéry, France
¹⁵Département d'Hématologie, CHU de Lyon, Pierre-Bénite, France