Sabina Chiaretti, MD, PhD¹, Matteo Leoncin^2*, Loredana Elia^1*, Stefano Soddu^3*, Alfonso Piciocchi^3*, Mabel Matarazzo^4*, Mariangela Di Trani^4*, Maurizio Martelli, MD^1*, Erika Borlenghi, MD^5*, Marina Parisi^6*, Valentina Mancini, MD^7*, Caterina Alati, MD^8*, Daniele G. Mattei, MD⁹, Maria Paola Martelli, MD, PhD^10*, Prassede Salutari, MD^11*, Patrizia Chiusolo, MD, PhD^12*, Ernesta Audisio, MD^13*, Mario Luppi, MD^14*, Lara Pochintesta^15*, Crescenza Pasciolla^16*, Bianca Serio, MD^17*, Barbara Scappini^18*, Antonella Cucca^19*, Martina Chiarucci^20*, Massimiliano Bonifacio, MD^21*, Nicola Fracchiolla^22*, Silvia Imbergamo^23*, Lucia Ammirati, MD^24*, Federico Mosna^25*, Patrizia Zappasodi^26*, Sara Mastaglio, MD^27*, Daniela Pietrasanta^28*, Monica Bocchia, MD^29*, Monia Lunghi^30*, Elisabetta Todisco^31*, Paola Fazi^3*, Alessandro Rambaldi³² and Robin Foà, MD^4*

¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy
²Azienda Ulss3 Serenissima,Hematology Unit, Ospedale dell'Angelo, Venezia, Italy
³GIMEMA Foundation, Rome, Italy
⁴Department of Translational and Precision Medicine, Division of Hematology, Sapienza University, Rome, Italy
⁵ASST Spedali Civili, Brescia, Department of Hematology, Brescia, Italy
⁶UO di Ematologia - Catania, Catania, Italy
⁷Department of Hematology and Oncology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy
⁸U.O.C. Ematologia, Grande Ospedale Metropolitano Bianchi Melacrino Morelli, Reggio Calabria, Italy
⁹ASO S. Croce e Carle, Cuneo, Italy
¹⁰Department of Medicine and Surgery, Division of Hematology and Clinical Immunology, University of Perugia, Perugia, Italy
¹¹Department of Hematology, Ospedale Civile Spirito Santo, Pescara, Pescara, Italy
¹²UOC Ematologia e Trapianto Cellule Staminali Emopoietiche, Fondazione Policlinico Universitario A. Gemelli IRCCS Roma, Rome, Italy
¹³SC Ematologia 2, AOU Città della Salute e della Scienza, Turin, Italy
¹⁴Hematology Unit and Chair, Department of Medical and Surgical Sciences, Azienda Ospedaliera Universitaria di Modena, University of Modena and Reggio Emilia, Modena, Italy
¹⁵ASL DI PIACENZA, OSPEDALE "GUGLIELMO DA SALICETO", Piacenza, Italy
¹⁶Ematologia, Istituto Tumori Giovanni Paolo II- Bari, Bari, Italy
¹⁷Department of Medicine and Surgery, University of Salerno, University of Salerno, Baronissi, Salerno, Italy
¹⁸Hematology Unit, Hematology Unit, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
¹⁹ASSL NUORO, PRESIDIO OSPEDALIERO SAN FRANCESCO, Nuoro, Italy
²⁰AO OSPEDALI RIUNITI MARCHE NORD - OSPEDALE SAN SALVATORE, Pesaro, Italy
²¹Department of Engineering for Innovation Medicine, Section of Innovation Biomedicine, Hematology Area, University of Verona, Verona, Italy
²²Hematology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy
²³Department of Medicine, Hematology and Clinical Immunology Unit, University of Padova, Padova, Italy
²⁴ASL Salerno - Presidio Ospedaliero Tortora Pagani, Pagani, Italy
²⁵Azienda Sanitaria dell'Alto Adige, Bolzano, ITA
²⁶Hematology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
²⁷Hematology and Bone Marrow Transplant, Unit San Raffaele Scientific Institute, Milano, Milano, Italy
²⁸Division of Hematology, Azienda Ospedaliera SS Arrigo E Biagio E Cesare Arrigo, Alessandria, ITA
²⁹Hematology, Azienda Ospedaliera Universitaria Senese, University of Siena, Siena, Italy
³⁰Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy
³¹Hematology and Stem Cell Transplantation Division, European Institute of Oncology, Milan, Italy
³²Hematology and Bone Marrow Transplant Unit, ASST Papa Giovanni XXIII, Bergamo, Italy

Shanshan Suo, MD^1*, Ying Lu^2*, Wenjuan Yu^1*, Chunmei Yang^1*, Lijing Shen^3*, Renzhi Pei^2*, Beiwen Ni^3*, Wanzhuo Xie, M.D.^1*, Liping Mao, M.D.^1*, Xingnong Ye^1*, Jiejing Qian^1*, Jing Wang, MD^4*, Bingzong Li, MD, PhD⁵, Xiaomin Wang^6*, Linjie Li^7*, Dan Zhao^8*, Yongming Xia^9*, Lihong Shou^10*, Yanping Shao^11*, Da Gao, MD^12*, Wenyuan Mai^1*, De Zhou, M.D.^1*, Gaixiang Xu^1*, Min Yang, M.D.^1*, Yinjun Lou, MD, PhD^1*, Hongyan Tong, PhD¹³, Huafeng Wang^1* and Jie Jin¹

¹Department of Hematology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
²Department of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo, China
³Department of Hematology, Renji hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⁴Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Centre for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China
⁵Department of Hematology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
⁶Department of Hematology, the First Hospital of Shanxi Medical University, Taiyuan, China
⁷Lishui Municipal Central Hospital, Lishui, CHN
⁸Department of Hematology, Yuncheng Central Hospital, Yuncheng, China
⁹Department of Hematology, Yuyao People's Hospital of Zhejiang Province, Yuyao, AL, China
¹⁰Department of Hematology, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, China
¹¹Department of Hematology,Taizhou Hospital Of Zhejiang Province, Taizhou, China
¹²The affiliated hospital of inner mongolia medical univuniversity, Hohhot, China
¹³Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China

Nicholas J. Short, MD¹, Hagop Kantarjian, MD¹, Nitin Jain, MD¹, Koichi Takahashi, MD, PhD², Ken Furudate, DMD, PhD^1*, Jayastu Senapati, MD, DM, MBBS¹, Fadi G. Haddad, MD¹, Omer Karrar^3*, Tapan M. Kadia, MD¹, Kelly S. Chien, MD⁴, Koji Sasaki, MD¹, Eitan Kugler^5*, Rebecca Garris^1*, Farhad Ravandi, MBBS⁶ and Elias Jabbour, MD¹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
³The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Department of Leukemia, MD Anderson, Houston, TX
⁵Department of Leukemia, MD Anderson Cancer Center, Houston, TX
⁶Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX

Michela Ansuinelli, MD^1*, Maria Stefania De Propris, MD, PhD^1*, Maria Cristina Puzzolo, PhD^1*, Nadia Peragine, PhD^1*, Tiziano Quacquarelli, BS^1*, Saveria Capria, MD^1*, Cristina Skert, MD^2*, Valentina Mancini, MD^3*, Simona Sica, MD, PhD^4*, Federico Lussana^5*, Erika Borlenghi, MD⁶, Marco Cerrano, MD^7*, Daniele Vallisa, MD^8*, Valeria Cardinali, MD^9*, Sabina Chiaretti, MD, PhD¹, Anna Guarini, PhD^10* and Robin Foà, MD^10*

¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy
²Azienda Ulss3 Serenissima,Hematology Unit, Ospedale dell'Angelo, Venezia, Italy
³Department of Hematology and Oncology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy
⁴Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica Sacro Cuore, Rome, Italy
⁵Hematology and Bone Marrow Transplant Unit, ASST Papa Giovanni XXIII, Bergamo, Italy
⁶Hematology, ASST Spedali Civili di Brescia, Brescia, Italy
⁷SC Ematologia AOU Città della Salute e della Scienza, Torino, To, Italy
⁸Hematology Unit, Ospedale Guglielmo da Saliceto, Piacenza, Italy
⁹Center for Hemato-Oncological Research (CREO), Department of Medicine and Surgery, University of Perugia, Perugia, Italy
¹⁰Department of Translational and Precision Medicine, Division of Hematology, Sapienza University, Rome, Italy

Jieping Lin^1*, Chenhao Ding^1*, Zicong Huang^1*, Cai Zihong^1*, Jia Li^1*, Zhixiang Wang^1*, Xiaofang Li^1*, Xuan Zhou^1*, Bailin He^2*, Wenhao Zhong^1*, Li Xuan^1*, Qifa Liu, MD³, Yang Xu^4* and Hongsheng Zhou^1,5,6*

¹Department of Hematology,Nanfang Hospital, Southern Medical University, Guangzhou, China
²Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China
³Guangzhou, China
⁴The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, Suzhou, China
⁵Guangdong Provincial Clinical Research Center for Hematologic Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, China
⁶Department of Hematology, People's Hospital of Ganzhou, Ganzhou, China

Heike Pfeifer^1*, Fabian Lang, MD^2*, Walter Fiedler, MD³, Matthias Stelljes, MD⁴, Folker Schneller, MD^5*, Björn Steffen, MD^6*, Boris Böll, MD^7*, Andreas Viardot, MD, PhD⁸, Christoph Faul, MD⁹, Lino L. Teichmann, MD^10*, Hendrik Poeck, MD¹¹, Joerg Westermann, MD¹², Kerstin Schäfer-Eckart, MD^13*, Thomas Heinicke, MD^14*, Thomas Burmeister, MD, PhD^15*, Stefan Schwartz, MD^16*, Monika Brueggemann, PhD^17*, Hubert Serve, MD¹⁸ and Nicola Goekbuget, MD⁶

¹Department of Medicine, Hematology/Oncology, Goethe University Frankfurt, University Hospital, Frankfurt/M., Germany
²Department of Medicine, Hematology/Oncology, Goethe University Frankfurt, University Hospital, Frankfurt/Main, Germany
³Department of Oncology, Hematology and Bone Marrow Transplantation with Division of Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
⁴Department of Medicine A (Hematology, Hemostaseology, Oncology, Pneumology), University of Muenster, Muenster, Germany
⁵Klinikum Rechts der Isar der TU München, Munich, Germany
⁶Department of Medicine, Hematology/Oncology, Goethe University Frankfurt, University Hospital, Frankfurt, Germany
⁷Department I of Internal Medicine and German Hodgkin Study Group (GHSG), University Hospital of Cologne; equal contribution, Cologne, Germany
⁸Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
⁹Department of Internal Medicine II, Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, Tübingen, Germany
¹⁰Department of Medicine III, University Hospital Bonn, Bonn, Germany
¹¹Internal Medicine III - Hematology and Oncology, University Hospital Regensburg, Regensburg, Germany
¹²Hematology, Oncology and Tumor Immunology, Campus Virchow Klinikum, Charite - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, DEU
¹³Department of Internal Medicine V, Paracelsus University Hospital Nuremberg, Nuremberg, Germany
¹⁴Department of Hematology and Oncology, University Hospital Magdeburg, Magdeburg, Sachsen-Anhalt, Germany
¹⁵Department of Hematology, Oncology and Cancer Immunology (Campus Virchow Klinikum), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität and Humboldt-Universität zu Berlin, Berlin, Germany
¹⁶Department of Hematology, Oncology and Cancer Immunology (Campus Benjamin Franklin), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität and Humboldt-Universität zu Berlin, Berlin, Germany
¹⁷University Hospital Schleswig-Holstein, Kiel, DEU
¹⁸Department of Medicine, Hematology/Oncology, Goethe-University Frankfurt, University Hospital, Frankfurt am Main, Germany