Julia Weisinger^1*, Jehane Fadlallah^2*, Christelle Barbet^3*, Francois Provot^4*, Pascale Poullin^5*, Antoine Neel^6*, Manon Marie^7*, Virginie Rieu^8*, Tarik Kanouni^9*, Olivier Moranne^10*, Elie Azoulay^11*, Bérangère Joly^12*, Agnès Veyradier^12* and Paul Coppo, MD^1*

¹Centre de Référence des Microangiopathies Thrombotiques, Service d'hématologie, Hôpital Saint Antoine, Assistance Publique-Hôpitaux de Paris and Sorbonne Université, Paris, France
²Service d'Immunopathologie Clinique, Saint Louis hospital, AP-HP, Paris, France
³Service de Néphrologie-Immunologie Clinique, CHRU de Tours, Tours, France
⁴Service de Néphrologie, Hôpital Albert Calmette, Lille, France
⁵Service d'Hémaphérèse, Hôpital de La Conception, CHU de Marseille, Marseille, France
⁶Service de Médecine Interne, CHU de Nantes, Nantes, France
⁷Service de Médecine Interne, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France
⁸Service de Médecine Interne, CHU de Clermont-Ferrand, Clermont-Ferrand, France
⁹Hopital Saint-Eloi, CHU de Montpellier, Montpellier, France
¹⁰CHU De Nimes, Nimes, France
¹¹Médecine Intensive Réanimation, Hôpital Saint Louis, AP-HP, Paris, France
¹²Service d'Hématologie biologique, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris Nord, Université Paris Cité, Paris, France

Senthil Sukumar, MD, MSc¹, Jenna Brown, B.A.^2*, Marshall Mazepa, MD³, Spero Cataland, MD⁴ and Shruti Chaturvedi, MBBS⁵

¹Section of Hematology-Oncology, Department of Medicine, Baylor College of Medicine, Houston, TX
²Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
³Division of Hematology, Oncology, and Transplantation, University of Minnesota, Minneapolis, MN
⁴Division of Hematology, The Ohio State University, Columbus, OH
⁵Division of Hematology, Department of Medicine, Johns Hopkins Hospital, BALTIMORE, MD

Marie Scully, MD¹, Claire Berger, MD, PhD^2*, Nathalie Biebuyck^3*, Santiago Bonanad Boix, MD^4*, Claire Dossier^5*, Wolf-Achim Hassenpflug, MD^6*, Karim Kentouche^7*, Beverly Schaefer, MD⁸, Silvia Maria Trisolini^9*, Runhui Wu, MD¹⁰, Juan Xiao^11*, Feng Xue, MD^12*, Björn Mellgård¹³, Munjal Patel^13*, Parth Patwari, MD, PhD^13*, Linda T. Wang^13*, Shan Xiao^13* and Pinghai Zhang^13*

¹Department of Haematology, University College London Hospital, Haematology Theme-NIHR UCLH/UCL BRC, London, United Kingdom
²University Hospital, Department of Paediatric Oncology, University Jean Monnet Saint-Étienne, Mines Saint-Etienne, Inserm, Sainbiose U1059, 42023 Saint-Etienne, France
³Department of Pediatric Nephrology, Hôpital Universitaire Necker-Enfants Malades, Assistance-Publique Hôpitaux de Paris, Paris, France
⁴Hemostasis and Thrombosis Unit, Department of Hematology, Hospital Universitari i Politècnic La Fe, Valencia, Spain
⁵Department of Pediatric Nephrology, Robert-Debré Hospital, Assistance Publique – Hôpitaux de Paris (AP-HP) and University of Paris, Paris, France
⁶Department of Pediatric Hematology and Oncology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany
⁷Section of Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Universitätsklinikum Jena, Jena, Germany
⁸University at Buffalo, Roswell Park Oishei Children's Cancer and Blood Disorders Program, Buffalo, NY
⁹Haematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy
¹⁰Hematology Department, National Center for Children's Health, Beijing Children's Hospital, Beijing, China
¹¹Department of Pediatrics, Peking Union Medical College Hospital, Peking Union Medical College Chinese Academy of Medical Sciences, Beijing, China
¹²Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin Key Laboratory of Gene Therapy for Blood Diseases, CAMS Key Laboratory of Gene Therapy for Blood Diseases, Tianjin, China
¹³Takeda Development Center Americas, Inc., Cambridge, MA

Adrienne Kaufman¹, Marshall Mazepa, MD² and Michael D Evans, MS^3*

¹Division of Hematology, Oncology and Transplantion, Unviersity of Minnesota, Scottsdale, AZ
²Division of Hematology, Oncology, and Transplantation, University of Minnesota, Minneapolis, MN
³University of Minnesota, Minneapolis, MN

Amelia K Haj, MD, PhD^1,2,3, Sean J. Jurgens, MD, MSc^2,4,5*, Xin Wang, MBBS^2,3*, Justine Ryu, MD^2,6, Seung Hoan Choi, PhD^2*, Patrick Ellinor, MD, PhD^2,3,4* and Pavan K Bendapudi, MD^2,3,7,8

¹Department of Pathology, Massachusetts General Hospital, Cambridge, MA
²The Broad Institute of MIT and Harvard, Cambridge, MA
³Harvard Medical School, Boston, MA
⁴Massachusetts General Hospital, Boston, MA
⁵Department of Experimental Cardiology, University of Amsterdam, Amsterdam, Netherlands
⁶Section of Hematology, Yale University School of Medicine, New Haven, CT
⁷Division of Thrombosis and Hemostasis, Beth Israel Deaconess Medical Center, Boston, MA
⁸Division of Hematology, Department of Medicine, Massachusetts General Hospital, Cambridge, MA

Shruti Chaturvedi, MBBS¹, Jenna Brown, B.A.^2*, Jia Yu³, Gloria F. Gerber, MD⁴ and Doris Lin^5*

¹Division of Hematology, Department of Medicine, Johns Hopkins Hospital, BALTIMORE, MD
²Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
³University of Pittsburgh School of Medicine, Pittsburgh, PA
⁴Division of Hematology, Johns Hopkins University, Baltimore, MD
⁵Johns Hopkins University, Baltimore, MD