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711.O1.6 711. Cell Collection and Manufacturing of HSPCs, CAR-T Cells, and Other Cellular Therapy Products: Innovations in Mobilization, Collection, and Manufacturing for Cellular Therapies

Symposia: Cell Collection and Manufacturing of HSPCs, CAR-T Cells, and Other Cellular Therapy Products Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Maternal Health, Research, Clinical trials, Sickle Cell Disease, Adult, Autoimmune disorders, Fundamental Science, Translational Research, Lymphomas, Autoimmune hemolytic anemia, Clinical Practice (Health Services and Quality), Clinical Research, Chimeric Antigen Receptor (CAR)-T Cell Therapies, Plasma Cell Disorders, B Cell lymphoma, Hemoglobinopathies, Hematopoiesis, Diseases, Immune Disorders, Cell expansion, Gene Therapy, Clinical procedures, Biological therapies, Treatment Considerations, Immunotherapy, Young adult , Lymphoid Malignancies, Emerging technologies, Biological Processes, Technology and Procedures, Gene editing, Study Population, Human, Animal model, Transplantation (Allogeneic and Autologous)
Saturday, December 7, 2024: 12:00 PM-1:30 PM
Room 25 (San Diego Convention Center)
Moderators:
Yvette C Tanhehco, MD, PhD, Columbia University and Patrick J. Hanley, PhD, Children's National Medical Center
Disclosures:
No relevant conflicts of interest to declare.
The theme of this oral session is mobilization and manufacturing of gene therapy, T cell adoptive immunotherapy, and CAR-T cell products.   The purpose of this session is to educate attendees on novel methods of mobilization and manufacturing of cellular therapy products.
12:00 PM

Zachary D. Crees, MD1, Michael P. Rettig, PhD1, Reyka G. Jayasinghe, PhD2*, Stephanie Christ, MS3*, Feng Gao4*, Hailey Sappington3*, Sana Saif Ur Rehman, MD5, Suzanne R. Thibodeaux, MD, PhD6*, Ella Sorani, PhD7*, Allison A. King, MD, PhD, MPH8 and John F. DiPersio, MD, PhD9

1Division of Oncology, Washington University School of Medicine, Saint Louis, MO
2Department of Internal Medicine, Division of Oncology, School of Medicine, Washington University, Saint Louis, MO
3Washington University, School of Medicine, St. Louis, MO
4Department of Surgery, Division of Public Health Sciences, Washington University School of Medicine, Saint Louis, MO
5Washington University, Saint Louis, MO
6Washington University School of Medicine, Saint Louis, MO
7BiolineRx, Modi'in, Israel
8School of Medicine, Washington University, Clayton, MO
9Washington University School of Medicine, St. Louis, MO

12:15 PM

Rachel M Levine, PhD1*, Erin A Dempsey, BA1*, Nikitha Nimmagadda, MS1*, Yoonjeong Jang, DVM, PhD1, Kalin Mayberry2*, Jingjing Zhang3*, David Cullins1*, Catherine Willis4*, Alicia Powers4*, Young-In Kim-Hoehammer5*, Jie Lin5*, Fei Zhang5*, Neha Das Gupta, PhD4*, Will Lewis5*, Varun Katta2*, Yichao Li, PhD1*, Timothy Lockey, PhD6*, Yong Cheng, PhD1, Patti Lehigh5*, Frank Fazio4*, Alexis Kristine Leonard, MD1, Akshay Sharma, MBBS7, Sheng Zhou, PhD8, Shengdar Q Tsai, PhD2, Mitchell J Weiss, MD, PhD2 and Jonathan S Yen, PhD2

1Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN
2Department of Hematology, St. Jude Childrens Research Hospital, Memphis, TN
3St. Jude Children Res. Hospital, Memphis, TN
4St. Jude Children's Research Hospital, Memphis, TN
5St. Jude Children's Research Hospital, Memphis
6Department of Therapeutics Production and Quality, St. Jude Children's Research Hospital, Memphis, TN
7Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN
8Experimental Cellular Therapeutics Laboratory, St. Jude Children's Research Hospital, Memphis, TN

12:30 PM

Antonio Pierini, MD, PhD1*, Loredana Ruggeri, MD, PhD2*, Valerio Viglione, MD1*, Simonetta Saldi, MD3*, Rebecca Sembenico, MD1*, Caridi Matteo, MD1*, Francesco Zorutti, MD1*, Anna Castaldo, MD1*, Alessandra Cipiciani, MD4*, Tiziana Zei5*, Roberta iacucci Ostini5*, Antonella Mancusi, PhD1*, Enrico Karim Jardini2*, Eni Hoxha1*, Adelmo Terenzi5*, Valeria Cardinali, MD, PhD2*, Roberta La Starza, MD6*, Cristina Mecucci, MD, PhD6, Andrea Velardi, MD, PhD1*, Massimo Fabrizio Martelli, MD, PhD1*, Maria Paola Martelli, MD, PhD1,2*, Cynthia Aristei, MD3* and Alessandra Carotti, MD2*

1Department of Medicine and Surgery, Division of Hematology and Clinical Immunology, University of Perugia, Perugia, Italy
2Department of Medicine and Surgery, Division of Hematology and Clinical Immunology, S. Maria della Misericordia Hospital, Perugia, Italy
3Department of Medicine and Surgery, Radiation Oncology Section, University of Perugia, Perugia, Italy
4Università politecnica delle Marche, Ancona, Italy
5S. Maria della Misericordia Hospital, Perugia, Italy
6Hematology, CREO, Centro Ricerche Emato-Oncologiche, University of Perugia, Perugia, Italy

12:45 PM

Dillon Jarrell, PhD1*, David Vereide, PhD1*, Cassidy Arnold, BS1*, Max Murphey1*, Ashley Yingst, MS, MBA1*, Ryan Koning, BS1*, Nikole Perdue2*, Artem Romanov1*, Celeste Busch1*, Igor Slukvin, MD3, Ryan Crisman, PhD1*, Ryan P. Larson, PhD2*, Andrew M. Scharenberg, MD2*, Branden Salinas1* and Samantha Ohara, PhD1*

1Umoja Biopharma, Louisville, CO
2Umoja Biopharma, Seattle, WA
3Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI

1:00 PM

Shuntaro Ikegawa, MD, PhD1*, Adam S. Sperling, MD, PhD1,2, Sarah Nikiforow, MD, PhD1,2, Andrew Ghazi, PhD3*, Anthony Christidis, PhD3*, David Quinn, BA4*, Dexiu Bu, MD, PhD4*, Jennifer Mataraza, PhD4*, David Pearson, PhD5*, Allison Charles, BS4*, Marc Credi, MA4*, Nina Orwitz, PhD6*, Madisyn Strange1*, Rakuyo Tamada, BA1*, Kevin M. Panaro, BS1*, Casey Gervais, MS1*, Michela Ansuinelli, MD, PhD1,7*, Yohei Arihara, MD, PhD8*, Rao Prabhala, PhD1,2*, Carol G. Reynolds, PhD1*, Robert Gentleman, PhD3*, Serena De Vita, MD, PhD4*, Nikhil C. Munshi, MD2,9 and Jerome Ritz, MD1,2

1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
2Harvard Medical School, Boston, MA
3Center for Computational Biomedicine, Harvard Medical School, Boston
4Novartis Biomedical Research, Cambridge, MA
5Novartis Biomedical Research, Basel, Switzerland
6Novartis Pharmaceuticals Corporation, East Hanover, NJ
7Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy
8The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan
9Dana-Farber Cancer Institute, The Jerome Lipper Multiple Myeloma Center, Boston, MA

1:15 PM

Peipei Zhu1*, Xiaofei Gao, PhD2*, Yang Yuan, Ph.D3*, Manman Lu3*, Qing Zhang3*, Menghao Ding3*, Lihong Jiang3*, Yaohuang Huang1* and Hsiang-Ying Lee, PhD4

1Westlake University, Hangzhou, China
2School of Life Sciences, Westlake University, Hangzhou, China
3Westlake Therapeutics, Hangzhou, China
4School of Life Sciences, Peking University, Beijing, China

*signifies non-member of ASH