Hiroto Ohguchi, MD/PhD^1*, Yasuyo Ohguchi^1*, Sho Kubota, PhD^2*, Takako Yokomizo-Nakano^2*, Ai Hamashima^2*, Kimi Araki, PhD^3* and Goro Sashida, MD, PhD²

¹Division of Disease Epigenetics, IRDA, Kumamoto University, Kumamoto, Japan
²Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan
³Institute of Resource Development and Analysis, Kumamoto University, Kumamoto, Japan

Jan Eckmann^1*, Carina Hage, PhD^1*, Lechner Stefanie^1*, Christa Bayer^1*, Christian Klein, PhD² and Pablo Umana, PhD²

¹Roche Innovation Center Munich, Roche/Genentech, Penzberg, Germany
²Roche Innovation Center Zurich, Roche/Genentech, Schlieren, Switzerland

Clara Leticia Andersson-Rusch^1*, Ingrid Quist-Løkken^1*, Pål Sætrom^1,2,3,4*, Vidar Beisvåg^1,5*, Milosz Rolinski^1*, Per Arne Aas^1*, Barbara van Loon^1* and Toril Holien, PhD^1,6,7,8

¹Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway
²Bioinformatics Core Facility - BioCore, Norwegian University of Science and Technology, Trondheim, Norway
³K.G. Jebsen Center for Genetic Epidemiology, Norwegian University of Science and Technology, Trondheim, Norway
⁴Department of Computer and Information Science, Norwegian University of Science and Technology, Trondheim, Norway
⁵St. Olavs Hospital, Trondheim, Norway
⁶Department of Hematology, St. Olavs Hospital, Ranheim, Norway
⁷Department of Biomedical Laboratory Science, Norwegian University of Science and Technology, Trondheim, Norway
⁸Department of Immunology and Transfusion Medicine, St. Olavs Hospital, Trondheim, Norway

Lanting Liu^1*, Lugui Qiu², Zhen Yu, MD^3* and Mu Hao^3*

¹Institute of Hematology and Blood Diseases Hospital Chinese Academy of Medical S, Tianjin, China
²State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology& Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
³State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, CHN

Emre Karayol^1*, Maria Moscvin, MD^1*, Tianzeng Chen^2*, Peter G. Czarnecki^3*, Annamaria Gulla, MD⁴, Kenneth C. Anderson, MD⁵ and Giada Bianchi, MD^2,6

¹Division of Hematology, Brigham and Women's Hospital, Boston, MA
²Amyloidosis Program, Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Boston, MA
³Division of Renal Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA
⁴Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA
⁵Dana-Farber Cancer Institute, Harvard Medical School, The Jerome Lipper Multiple Myeloma Center, Boston, MA
⁶Harvard Medical School, Boston, MA

Max Alberto Mendez-Lopez^1*, Andrej Besse^1,2*, Tiberiu Totu^3,4,5*, Marianne Kraus^1*, Anthonius P.A. Janssen^6*, Marija Buljan^3,4*, Mario Van Der Stelt^6*, Lenka Besse^2,7* and Christoph Driessen, MD¹

¹Clinics for Medical Oncology and Hematology, Laboratory of Experimental Oncology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland
²Faculty of Medicine, Department of Biology, Masaryk University, Brno, Czech Republic
³Empa, Swiss Federal Laboratories for Materials Science and Technology, St. Gallen, Switzerland
⁴SIB, Swiss Institute of Bioinformatics, Lausanne, Switzerland
⁵Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland
⁶Leiden Institute of Chemistry, Department of Molecular Physiology, Leiden University & Oncode Institute, Leiden, Netherlands
⁷Division of Oncology and Hematology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland

Hong Phuong Nguyen, PhD¹, Anh Quynh Le, PhD^1*, Enze Liu, PhD^2*, Brian A. Walker, PhD² and Ngoc Tung Tran, PhD¹

¹Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN
²Melvin and Bren Simon Comprehensive Cancer Center, Division of Hematology and Oncology, Indiana University School of Medicine, Indianapolis, IN

Michael Amatangelo^1*, Erin Flynt, PhD^2*, Nicholas Stong^1*, Maria Ortiz, Ph.D.^3*, Pradipta Ray^1*, Maria Wang^1*, Niels W.C.J. van de Donk^4,5*, Sagar Lonial, MD^6*, Aparna Raval^1* and Anita K. Gandhi, PhD²

¹Bristol Myers Squibb, Princeton, NJ
²Bristol Myers Squibb, Summit, NJ
³CITRE, Bristol Myers Squibb, Seville, Spain
⁴Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Department of Hematology, Amsterdam, Netherlands
⁵Cancer Center Amsterdam, Amsterdam, Netherlands
⁶Department of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA

David Sharon^1*, Valerie Robinson^1*, Claudie Hecquet^1*, Kelly Calabrese^1*, Cormac Cosgrove^1*, Christine Mantis^1*, Orlando Bueno, MD, PhD², Aarif Ahsan^1*, Adam Chervin^1*, PK Epling-Burnette, PharmD, PhD^1* and Jeremy A Ross, PhD^2*

¹AbbVie, Inc., North Chicago, IL
²AbbVie Inc., North Chicago, IL

Jian Cui^1*, Xiaoyun Li^2*, Shuhui Deng^3*, Lugui Qiu⁴, Xin Gao^5* and Gang An^6*

¹Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, TIANJIN, CHN
²State Key Laboratory of Experimental Hematology, National Clinical Research Cent, Tianjin, CHN
³State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical Colleg, Tianjin, CHN
⁴State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology& Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
⁵Institute of Hematology, Chinese Academy of Medical Sciences, Tianjin, CHN
⁶State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences&Peking Union Medical College, Tianjin, China

Richa Mishra, PhD¹, Katelyn Bagwill^1*, Savannah Gonzales^1*, Vanessa Brizuela^1*, Prasanth Thunuguntla^1*, Yoon Jae Chang^1*, Reyka G. Jayasinghe, PhD^1*, Julie Fortier, PhD^2*, Mark A. Schroeder, MD^1,3, Li Ding, PhD^1,3*, Ravi Vij, MD, MBA^2,3, John DiPersio^1,3 and Jessica Silva-Fisher, PhD^1,3*

¹Department of Internal Medicine, Division of Oncology, School of Medicine, Washington University, Saint Louis, MO
²Division of Oncology, Washington University School of Medicine, Saint Louis, MO
³Siteman Cancer Center, Washington University, Saint Louis, MO

Metin Gunes, PhD^1*, Steven T. Rosen, MD¹ and Emine Gulsen Gunes, PhD^1,2,3

¹Department of Hematology and Hematopoietic Cell Transplantation, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA
²Toni Stephenson Lymphoma Center, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA
³Judy and Bernard Briskin Center for Multiple Myeloma Research, City of Hope National Medical Center, Duarte, CA

Jia Zhou^1*, Deeksha Vishwamitra, PhD², Yue Guo, PhD^2*, Raluca Verona, PhD², Alfredo Perales Puchalt^1*, Tara Stephenson, PhD^2*, Caroline Hodin^3*, Arnob Banerjee^2*, Katherine Chastain, MD⁴, Nahor Haddish-Berhane^1* and Weirong Wang^1*

¹Janssen Research & Development, LLC, Spring House, PA
²Janssen Research & Development, Spring House, PA
³Janssen Research & Development BE, Antwerp, Belgium
⁴Janssen Research & Development, Raritan, NJ

Elizabeth K. O'Donnell, MD¹, Clifton C. Mo, MD¹, Andrew J. Yee, MD², Omar Nadeem, MD¹, Andrew R. Branagan, MD³, Jacob Laubach⁴, Jacalyn Rosenblatt, MD⁵, Nora Horick^6*, Paul G. Richardson, MD⁷, Noopur Raje, MD⁸ and Diana Cirstea, MD^8*

¹Dana-Farber Cancer Institute, Boston, MA
²Massachusetts General Hospital Cancer Center, Boston, MA
³Center for Multiple Myeloma, Massachusetts General Hospital Cancer Center, Boston, MA
⁴Dana-Farber/Partners CancerCare, Harvard Medical School, Boston, MA
⁵Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
⁶Massachusetts General Hospital, Boston
⁷Dana-Farber Cancer Institute, Inc., Boston, MA
⁸Harvard Medical School, Massachusetts General Hospital Cancer Center, Boston, MA

Baohui Wang^*, Xiao Huang^*, Jianming Sun^*, Yurong Qin^*, Hongyan Shang^*, Tingting Li^*, Guojin Wu^*, Min Chen^*, Hailin Wang^*, Peng Zhang^*, Duqing Jiang^*, Tongjun Liu^*, Mi Ye^*, Shengli Cai^*, Shoupeng Lai^*, Xiaoqiang Kang^* and Hong Ling^*

Nanjing Leads Biolabs Co., Ltd., Nanjing, China

Shanshan Zhang^1*, Linjing Cai^2*, Zhang Hanzhen^3*, Yuqi Wang^4*, Chen Huan, MBBS^5*, Xiaolei Wei, MD^6* and Qifa Liu, MD⁷

¹Department of Hematology, Department of Hematology, Nanfang Hospital, Southern medical university, Guangzhou, China
²Department of Hematology, Nanfang Hospital, Guangzhou, China
³Department of Hematology, Nanfang Hospital, Southern Medical University, Guangdong, China
⁴Nanfang hospital, Guangzhou, AL, China
⁵Southern Medical University, GuangZhou, China
⁶Department of Hematology, Nanfang Hospital of Southern Medical University, Guangzhou, China
⁷Nanfang Hospital, Southern Medical University, Guangzhou, China

Jia Liu^*, Zilu Zhang^*, Wenbin Xu^*, Ming-Yuan Jia^*, Chengyu Wu^* and Yan Hua, PhD^*

Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

Sumi Roy, PhD^*, Adriana Del Cid, BS^*, Kai Lu, BS^*, Giovanni Diaz, PhD^*, Gulay Bengu Ulukaya, PhD^*, Servando Palencia, AS^*, Rin Nakamura, BS^*, Christopher R. Bolen, PhD^* and Katerina Hatzi, PhD^*

Genentech, Inc., South San Francisco, CA

Beñat Ariceta^1*, Alice Nevone, PhD^2,3*, Itziar Cenzano, PhD^1*, Ane Amundarain^1*, Amaia Vilas-Zornoza^1*, Leire Garate^1,4,5*, Paula Aguirre-Ruiz^1*, Estibaliz Miranda^1*, Patxi San-Martin^1*, Paolo Milani, MD, PhD^2,3, Ramon Lecumberri Villamediana^4,5*, Diego Alignani^1*, Giovanni Palladini, MD, PhD^2,3, Bruno Paiva^1*, Jose Ignacio Martin-Subero^6,7*, Giampaolo Merlini, MD^2,3*, Jesus San-Miguel, MD, PhD^4,5, Mikel Hernaez, PhD^8,9*, David Gomez-Cabrero, PhD^10,11*, Xabier Agirre, PhD^1*, Mario Nuvolone, MD, PhD^2,3* and Felipe Prosper, MD, PhD^1,5,12

¹Hematology and Oncology Program, Centre for Applied Medical Research (CIMA), Instituto de Investigaciones Sanitarias de Navarra (IdiSNA), Cancer Center Clinica Universidad de Navarra (CCUN), Pamplona, Spain
²Department of Molecular Medicine, University of Pavia, Pavia, Italy
³Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
⁴Hematology and Cell Therapy Department. Clinica Universidad de Navarra, Instituto de Investigaciones Sanitarias de Navarra (IdiSNA), Cancer Center Clinica Universidad de Navarra (CCUN), Pamplona, Spain
⁵Centro de Investigacion Biomedica en Red de Cancer (CIBERONC), Madrid, Spain
⁶Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
⁷Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain
⁸Data Science and Artificial Intelligence Institute (DATAI). Universidad de Navarra., Pamplona, Spain
⁹Computational Biology Program. Cima Universidad de Navarra. IdiSNA., Pamplona, Spain
¹⁰Bioscience Program, Biological and Environmental Sciences and Engineering Division (BESE), King Abdullah University of Science and Technology KAUST, Thuwal, Saudi Arabia
¹¹Translational Bioinformatics Unit, Navarrabiomed, Universidad Pública de Navarra (UPNA), Pamplona, Spain
¹²Hematology and Cell Therapy Department, Clinica Universidad de Navarra, Instituto de Investigaciones Sanitarias de Navarra (IdiSNA), Cancer Center Clinica Universidad de Navarra (CCUN), Pamplona, Spain

Glykeria Gkoliou^1,2*, Nikolaos Pechlivanis^1,3*, Sofia Chatzileontiadou^4*, Chara Xydopoulou^2*, Christina Frouzaki^4*, Georgios Karakatsoulis^1*, Elisavet Vlachonikola^1*, Marina Gerousi^1*, Fotis Psomopoulos^1*, Maria Papaioannou^4*, Katerina Chlichlia^2*, Kostas Stamatopoulos^1,5, Evdoxia Hatjiharissi^4* and Anastasia Chatzidimitriou^1,5*

¹Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece
²Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupoli, Greece
³Department of Genetics, Development and Molecular Biology, School of Biology, Aristotle University of Thessaloniki, Thessaloniki, Greece
⁴First Department of Internal Medicine, Division of Hematology, AHEPA University Hospital, Aristotle University of Thessaloniki, School of Medicine, Thessaloniki, Greece
⁵Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden

Ciara Louise L. Freeman, MD, PhD, MSc¹, Meghan Menges^2*, Jerald Noble, PhD^2*, Raghunandan Reddy Alugubelli^3*, Rafael Renatino-Canevarolo, PhD^4*, Oliver Hampton, PhD, MSc^5*, Praneeth Reddy Sudalagunta, PhD^6*, Salvatore Corallo^7*, Ariosto Siqueira Silva, PhD^6*, Mark B Meads, PhD^3*, Rachid Baz, MD⁸, Melissa Alsina, MD^1*, Doris K. Hansen, MD⁷, Taiga Nishihori, MD⁷, Omar Castaneda, MD⁹, Brandon Blue, MD⁸, Ariel F. Grajales-Cruz, MD⁶, Yunfei Wang^10*, Patrick Hwu^2*, John Koomen^4*, Kenneth H. Shain, MD, PhD¹¹ and Frederick L. Locke, MD⁷

¹H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
²Moffitt Cancer Center, Tampa, FL
³Department of Malignant Hematology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
⁴H. Lee Moffitt Cancer Center, Tampa, FL
⁵M2GEN, Tampa, FL
⁶H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
⁷Department of Blood and Marrow Transplantation and Cellular Immunotherapy, Moffitt Cancer Center, Tampa, FL
⁸Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁹Department of Blood and Marrow Transplant and Cellular Immunotherapy, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
¹⁰Department of Clinical Science, Moffitt Cancer Center, Tampa, FL
¹¹H. Lee Moffitt Cancer Center & Research Institute, Saint Petersburg, FL

Xinyi Zhou^1*, Ying Yang^1*, Xiaoli Hu^1*, Tiancheng Luo^1*, Shangrun Liu^1*, Chao Zhang^2* and Juan Du¹

¹Department of Hematology, Myeloma & Lymphoma Center, Shanghai Changzheng Hospital, Naval Medical University, Shanghai, China
²Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medici, Shanghai, China

Martina Chiu, PhD^1*, Erika Griffini, MSc^1*, Denise Toscani, PhD^1*, Giuseppe Taurino, PhD^1*, Chiara Maccari, MSc^1*, Roberta Andreoli, PhD^1*, Giovanna D'Amico, BSc, PhD, MSc^2*, Nicola Giuliani, MD, PhD¹ and Ovidio Bussolati, MD, PhD^1*

¹Department of Medicine and Surgery, University of Parma, Parma, Italy
²Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy

Alina Dulau-Florea, MD^1*, Raul C. Braylan, MD², Yanna Ding^3*, Nisha Patel, DO⁴, Katherine Calvo, MD, PhD⁵, Elizabeth Hill, MD^3*, Emma M. Groarke, MD^6,7, Neal S. Young, MD^7,8 and Bhavisha A. Patel, MD^7,9

¹Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD
²National Institutes of Health, Bethesda, MD
³National Cancer Institute, National Institutes of Health, Bethesda, MD
⁴Hematology Service, Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD
⁵National Institutes of Health Clinical Center, Bethesda, MD
⁶Hematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD
⁷Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
⁸National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health, Bethesda, MD
⁹Hematology Branch, National Heart, Lung, and Blood Institute. National Institutes of Health, Bethesda, MD

Enrico La Spina^1*, Salvatore Cortellino^2*, Cesarina Giallongo, PhD^3*, Marisabel Mecca^4*, Simona Picerno^4*, Angela Amoresano^5*, Gabriella Pinto^6*, Stefania Serpico^5*, Alessandro Sgambato^7*, Grazia Scandura^1*, Daniela Cambria^1*, Daniele Tibullo^8*, Antonino Neri, MD^9*, Francesco Di Raimondo, MD¹⁰ and Alessandra Romano, MD, PhD^11*

¹Divisione di Ematologia, Dipartimento di Chirurgia e Specialità Medico Chirurgiche, Università degli Studi di Catania, Catania, Italy
²Laboratory of Pre-Clinical and Translational Research, IRCCS-CROB, Referral Cancer Center of Basilicata, Rionero in Vulture, Italy
³Università degli Studi di Catania, Catania, CT, ITA
⁴IRCCS-CROB, Referral Cancer Center of Basilicata, Laboratory of Pre-Clinical and Translational Research, Rionero in Vulture, Italy
⁵Department of Chemical Sciences, University of Naples Federico II, Napoli, Italy
⁶Department of Chemical Science, University of Naples, Napoli, Italy
⁷Catholic University of Rome, Roma, ITA
⁸Università degli Studi di Catania, Catania, ITA
⁹Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy
¹⁰Haematology, A.O.U. Policlinico “G. Rodolico-San Marco”, Catania, Italy
¹¹Divisione di Ematologia, Dipartimento di Chirurgia e Specialità Medico Chirurgiche, Università degli Studi di Catania, Tremestieri Etneo, Cantania, Italy

David Coffey, MD¹, Ola Landgren, MD², Andrew J. Cowan, MD³, Pinar Ataca Atilla, MD^4*, Sylvain Simon, PhD^4*, Margot Pont^5*, Melissa L Comstock^4*, Geoffrey R Hill, MD⁴, Stanley R. Riddell, MD⁴ and Damian J Green, MD⁴

¹Myeloma Division, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
²Sylvester Comprehensive Cancer Center, Myeloma Division, University of Miami, Miami, FL
³Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA
⁴Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA
⁵CellPoint BV, a Galapagos company, Oegstgeest, Netherlands

Alana L. Keller, BS¹, Sarah E. Parzych, BA^1*, Lauren T. Reiman, BS^1*, Zachary J. Walker, BS, MS^1*, Peter A. Forsberg, MD^2* and Daniel W. Sherbenou, MD, PhD¹

¹Division of Hematology, University of Colorado Anschutz Medical Campus, Aurora, CO
²Division of Hematology, University of Colorado Health Blood Disorders and Cell Therapies Center, Aurora, CO

Susan Bal, MD¹, Esther Zumaquero^1*, Gayathri Ravi, MD¹, Kelly Godby, MD^1*, Smith Giri, MD, MS^1*, Ashley Denslow^1*, Joaquin Bauta Perez^1*, Fen Zhou^2*, Suki Chen^2*, Megan Padilla^2*, Amna Siddiqui^2*, Clare Ubersax, BS^1*, Erin Hornsby^2*, Luciano Costa, MD, PhD¹ and Frances E Lund^2*

¹University of Alabama at Birmingham, Birmingham, AL
²University of Alabama at Birmingham, Birmingham

Lucia Y Chen, MD^1,2*, Oliver Van Oekelen, MD, PhD³, Michael Amatangelo, PhD^4*, Tracy T. Chow^4*, Bhaskar Upadhyaya, PhD^1*, Alessandro Lagana, PhD¹, Geoffrey Kelly^5*, Seunghee Kim-Schulze, PhD^6*, Adolfo Aleman, MPA¹, Antonina Kurtova, PhD^7*, Sarah Gooding^2,8,9*, Sundar Jagannath, MD¹, Erin Flynt, PhD^4*, Anita K. Gandhi, PhD⁴, Udo Oppermann, PhD^9*, Anjan Thakurta, PhD^9,10 and Samir Parekh, MD¹

¹Department of Medicine, Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York
²Department of Haematology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
³Department of Medicine, Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
⁴Bristol Myers Squibb, Summit, NJ
⁵Department of Immunology & Immunotherapy, Icahn School of Medicine At Mount Sinai, New York, NY
⁶Department of Immunology & Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY
⁷Bristol Myers Squibb, San Francisco
⁸MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
⁹Oxford Translational Myeloma Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford, United Kingdom
¹⁰Oxford Translational Myeloma Centre, University of Oxford, Oxford, United Kingdom

Lijie Xing, MD^1*, Jiye Liu, PhD^2*, Kenneth Wen, BS^2*, Teru Hideshima^2*, Kenneth C. Anderson, MD³ and Zengjun Li^4*

¹Department of Lymphoma and Hematology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Brookline, MA
²Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
³Dana-Farber Cancer Institute, Harvard Medical School, The Jerome Lipper Multiple Myeloma Center, Boston, MA
⁴Department of Lymphoma and Hematology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Ji'nan, Shandong, China

Holly Lee, MD^1*, Michael Durante, PhD^2*, Sungwoo Ahn, PhD^1*, Noemie Leblay, PhD^1*, Mansour Poorebrahim, PhD^1*, Ranjan Maity, PhD^1*, Rémi Tilmont, MD^1*, Elie Barakat^1*, David Jung^1*, Bachisio Ziccheddu^2*, Alexis Brake^2*, Ola Landgren, MD², Benjamin Diamond, MD³, Francesco Maura, MD⁴, Paola Neri, MD, PhD⁵ and Nizar J Bahlis, MD⁵

¹Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Canada
²Sylvester Comprehensive Cancer Center, Myeloma Division, University of Miami, Miami, FL
³Myeloma Division, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
⁴Sylvester Comprehensive Cancer Center, Myeloma Division, University of Miami, PALMETTO BAY, FL
⁵Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada

Pankaj Kumar Singh, PhD^1*, Frances N. Cervoni Curet, MD^1*, Cody T. Clayhold, BA^2*, Isere Kuiatse, PhD^1*, Wei Tan^1*, Marco Meloni, PhD^3*, Monsif Bouaboula, PhD^3*, Kamlesh Bisht, PhD^3*, Helgi J. Van de Velde, MD, PhD³, Marielle Chiron, PhD^4*, Angela Virone-Oddos, PhD^4* and Robert Z. Orlowski, MD, PhD^5,6

¹Department of Lymphoma & Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
²Seattle Children's Research Institute, Seattle, WA
³Sanofi R&D, North America, Cambridge, MA
⁴Sanofi R&D, Vitry-sur-Seine, France
⁵Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
⁶Department of Experimental Therapeutics, MD Anderson Cancer Center, Houston, TX

Antonio Sacco, MSc^1*, Vanessa Desantis, PhD^2*, Jon Celay, PhD^3*, Viviana Giustini, MSc^4*, Fabio Rigali, MSc^1*, Francesco Savino, MD^1*, Michele Cea^5*, Debora Soncini^6*, Antonia Cagnetta, MD^5*, Antonio Giovanni Solimando, MD, PhD^7*, Deborah D'Aliberti, PhD^8*, Silvia Spinelli, MSc^8*, Daniele Ramazzotti, PhD^8*, Camillo Almici, MD^9*, Katia Todoerti, PhD^10*, Antonino Neri, MD^11*, Antonella Anastasia, MD^12*, Alessandra Tucci, MD¹², Marina Motta, MD^12*, Marco Chiarini, PhD^13*, Yawara Kawano, MD, PhD¹⁴, Jose A Martinez-Climent, MD PhD³, Rocco Piazza, MD, PhD^8* and Aldo Roccaro, MD, PhD¹

¹Clinical Trial Center, Translational Research and Phase I Unit, ASST Spedali Civili di Brescia, Brescia, Italy
²Department of Biomedical Sciences and Human Oncology (DIMO), Pharmacology Section, University of Bari Medical School, Bari, AL, ITA
³Hematology and Oncology Program, Centre for Applied Medical Research (CIMA), Instituto de Investigaciones Sanitarias de Navarra (IdiSNA), Cancer Center Clinica Universidad de Navarra (CCUN), Pamplona, Navarra, Spain
⁴Clinical Chemistry Laboratory, Flow Cytometry Section Asst Spedali Civili di Brescia, Brescia, ITA
⁵Clinic of Hematology, Department of Internal Medicine (DiMI), IRCCS Ospedale Policlinico San Martino, Genova, Italy
⁶Clinic of Hematology, Department of Internal Medicine and Medical Specialties (DiMI), University of Genoa, Genova, Italy
⁷Guido Baccelli Unit of Internal Medicine, Department of Biomedical Sciences and Human Oncology, University of Bari, Bari, Italy
⁸Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy
⁹Laboratory for Stem Cells Manipulation and Cryopreservation, Department of Transfusion Medicine, ASST Spedali Civili of Brescia, Brescia, Italy
¹⁰Department of Oncology and Hemato-Oncology, Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, MI, ITA
¹¹Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy
¹²Hematology, ASST Spedali Civili, Brescia, Italy
¹³Clinical Chemistry Laboratory, Flow Cytometry Section, ASST Spedali Civili di Brescia, Brescia, ITA
¹⁴Dept of Hematology, Kumamoto University Hospital, Kumamoto, Japan

Xiaoxuan Xu, MD, PhD^*, Wei Zhou, M.D.^*, Tingfen Deng, M.D.^*, Qinghua Cai^* and Shunqing Wang, M.D., Ph.D.^*

Department of Hematology, Guangzhou First People's Hospital, the Second Affiliated Hospital of South China University of Technology, Guangzhou, China

Gerard Hilinski, PhD^1*, Blaise Stearns, M.Sc^2*, Sandip Vibhute, PhD^1*, Tiffany Hughes^1*, Susheela Tridandapani, PhD¹, Megan E. Johnstone, PhD^2*, Thomas E. Goodwin, PhD^3*, Jeffrey Patrick, PharmD^1*, Chad E. Bennett, PhD^1*, Don Benson, MD⁴, John C. Byrd, MD², Ola A. Elgamal, PhD² and Erin K. Hertlein, PhD²

¹The Ohio State University, Columbus, OH
²Department of Internal Medicine, University of Cincinnati, Cincinnati, OH
³Hendrix College, Conway, AR
⁴Ohio State University Medical Center, Columbus, OH