Willian R. Gomes, MSc^1*, Vinicius S. Carvalho, MsC^2*, Edson Z. Martinez, PhD^2*, Shan Hama, MSc^3*, Mohammad M. Karimi, PhD^4*, Giorgio Napolitani, PhD^4*, Ghulam Mufti, DM, FRCPath^4* and Rodrigo T. Calado, MD, PhD²

¹Ribeirao Preto School of Medicine, University of Sao Paulo, RIBEIRAO PRETO, AL, Brazil
²Ribeirao Preto School of Medicine, University of Sao Paulo, Ribeirao Preto, Brazil
³King’s College London, Comprehensive Cancer Centre, School of Cancer and Pharmaceutical Sciences, London, ENG, United Kingdom
⁴King’s College London, Comprehensive Cancer Centre, School of Cancer and Pharmaceutical Sciences, London, United Kingdom

Zuzanna Rydzynska, MSc^1*, Dawid Grzela, PhD^1,2*, Monika I Linder^3*, Weronika Dobrewa, MSc^4*, Zuzanna Urbanska^1*, Bartlomiej Pawlik, MSc^1*, Damian Krzyzanowski, PhD^1,2*, Maciej Mazurek, MSc^1*, Szymon Janczar, MD, PhD^1*, Joanna Madzio, PhD^1* and Wojciech Mlynarski, MD, PhD^1*

¹Department of Pediatrics, Oncology and Hematology, Medical University of Lodz, Lodz, Poland
²Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland
³Department of Pediatrics, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-Universität, Munich, Germany
⁴Department of Pediatrics, Oncology and Hematology, Medical University of Lodz, Lódz, Poland

Ana Catarina Menezes, PhD¹, Natalie Deuitch, MS^1*, Abdel G. Elkahloun, PhD^2* and Paul Pu Liu, MD, PhD¹

¹Oncogenesis and Development Section, National Human Genome Research Institute, NIH, Bethesda, MD
²Microarray Core, National Human Genome Research Institute, NIH, Bethesda, MD

Joshua Baiel, MD^1*, Daniel J Wegner, MS^1*, Jennifer A Wambach, MD^1* and Julia T. Warren, MD, PhD^2,3

¹Edward Mallinckrodt Department of Pediatrics, Washington University in St. Louis, St. Louis, MO
²Department of Pediatrics, University of Pennsylvania, Philadelphia, PA
³Division of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA

Alejandro Ferrer, PhD¹, Zachary D Stephens, Ph.D.^2*, Susan M. Geyer, PhD³, Rachel A Simon^4*, Terra L. Lasho, PhD⁵, Christy M Finke^5*, Brittany Burnap^1*, Lindsay A Mulvihill, CCRP^6*, Tammy M McAllister, M.A.^6*, Carolyn R. Rohrer Vitek, Ed.D. / M.S.^6*, Konstantinos N Lazaridis^1*, Angita Jain^7*, Eric W Klee, PhD^8*, Jean-Pierre A Kocher, Ph.D.^8* and Mrinal M. Patnaik, MD, MBBS⁴

¹Mayo Clinic, Rochester, MN
²Department of Computational Biology, Mayo Clinic, Rochester, MN
³Alliance Statistics and Data Management Center, Mayo Clinic, Rochester, MN
⁴Division of Hematology, Mayo Clinic, Rochester, MN
⁵Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN
⁶Center for Individualized Medicine, Mayo Clinic, Rochester, MN
⁷Mayo Clinic, Jacksonville, FL
⁸Computational Biology, Mayo Clinic, Rochester, MN

Timothy Chlon, PhD¹, Emily Stepanchick^2*, Christy M Finke^3*, Terra L. Lasho, PhD³, Talha Badar, MD⁴, Alejandro Ferrer, PhD⁵ and Mrinal M. Patnaik, MD, MBBS³

¹Cincinnati Children's Hospital, Cincinnati, OH
²Cancer and Blood Diseases Institute, Cincinnati Children's Hospital, Cincinnati, OH
³Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN
⁴Mayo Clinic, Jacksonville, FL
⁵Mayo Clinic, Rochester, MN

Noa Greenberg-Kushnir, MD^1*, Assaf Arie Barg^2*, Ginette Schiby, MD^1*, Corine Mardoukh, MD^1*, Nira Varda-Bloom, PhD^3*, Diana Bar^1*, Yair Anikster, MD, PhD^4*, Bella Bielorai, MD^4*, Amos Toren, MD, PhD^1* and Elad Jacoby, MD⁵

¹Sheba Medical Center, Ramat Gan, Israel
²National Hemophilia Center, Sheba Medical Center, Tel Hashomer, Israel; Amalia Biron Research Institute of Thrombosis and Hemostasis, Tel Aviv University, Israel., Tel Aviv, Israel
³Tel-Hashomer, Sheba Medical Center, Ramat-Gan, Israel
⁴Sheba Medical Center, Ramat-Gan, Israel
⁵Department of Pediatric Hematology-Oncology, Safra Children's Hospital, Sheba Medical Center, Ramat Gan, Israel

Clarissa Gervasoni^1*, Nadia Bertola^2*, Alice Martina Giussani^1*, Erica Dander, PhD^1*, Valentino Bezzerri, PhD^3*, Andrea Biondi, MD^4,5, Paola Corti, MD^4*, Piero Farruggia, MD^6*, Giovanna Giagnuolo^7*, Giuseppe Menna, MD^7*, Anna Pegoraro, MD^3*, Simone Cesaro^8*, Marco Cipolli, MD^3*, Carlo Dufour, MD⁹, Silvia Ravera, PhD^10* and Giovanna D'Amico, BSc, PhD, MSc^1*

¹Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy
²Molecular Pathology Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy
³Cystic Fibrosis Center, Azienda Ospedaliera Universitaria Integrata, Verona, Italy
⁴Pediatrics, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy
⁵School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy
⁶Ospedali "Civico Di Cristina Benfratelli", Palermo, Italy
⁷Pediatric Hemato-Oncology Unit, Santobono-Pausilipon Hospital, Naples, Italy
⁸Pediatric Hematology-Oncology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy
⁹Hematology Unit, IRCCS G. Gaslini Children's Hospital, Genova, Italy
¹⁰Department of Experimental Medicine, University of Genoa, Genoa, Italy

Jana Block^1,2,3*, Christina Rashkova^1,2,3,4*, Irinka Castanon^2*, Jessica Platon^5*, Samaneh Zoghi^2,3*, Mitsuhiro Fujiwara^6*, Beatriz Chaves^7,8,9*, Rouven Schoppmeyer^10,11,12*, Caspar Van Der Made^13,14*, Rocio Cabrera-Perez^15*, Frederike Leonie Harms^16*, Rico Chandra Ardy^1,2,3*, Samin Alavi^17*, Laia Alsina^18,19,20*, Rainiero Avila Polo^15*, Paula Sanchez Moreno^21*, Raul Jimenez Heredia^1,2,3,4*, Thomas Hannich^3*, Johannes Huppa^22*, Martin Distel^1*, Winfried Pickl^23,24*, Jeffrey Yoder^25*, David Traver^26*, Karin Engelhardt^27*, Tobias Linden^28*, Leo Kager^1,4,29*, Sophie Hambleton^27*, Alexander Hoischen^13,14*, Sabine Illsinger^28,30*, Zahra Chavoshzadeh^31*, Kerstin Kutsche^16*, Lydie Da Costa^5,32,33,34*, Jaap Van Buul^10,11,12*, Joan Calzada-Hernandez^19,35*, Jordi Anton^19,20,35*, Olaf Neth^21*, Julien Viaud^36*, Akihiko Nishikimi^6*, Loic Dupre^2,7,37* and Kaan Boztug^1,2,3,4,29*

¹St. Anna Children's Cancer Research Institute, Vienna, Austria
²Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria
³CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
⁴Medical University of Vienna, Department of Pediatrics and Adolescent Medicine, Vienna, Austria
⁵HEMATIM UR4666, Université de Picardie Jules Verne, Amiens, France
⁶Biosafety Division, Research Institute, National Center for Geriatrics and Gerontology, Obu, Japan
⁷Toulouse Institute for Infectious and Inflammatory Diseases, INSERM, CNRS, Paul Sabatier Universtiy, Toulouse, France
⁸National Institute of Science and Technology on Neuroimmunomodulation, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil
⁹Computational Modeling Group, Oswaldo Cruz Foundation (Fiocruz), Eusebio, Brazil
¹⁰Molecular Cell Biology Lab, Department of Molecular Hematology, Sanquin Research, Amsterdam, Netherlands
¹¹Vascular Cell Biology Lab, Department of Medical Biochemistry, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands
¹²Leeuwenhoek Center for Advanced Microscopy, Section of Molecular Cytology, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, Netherlands
¹³Radboud University Medical Center for Infectious Diseases (RCI), Department of Internal Medicine, Radboud University Medical Center, Nijmegen, Netherlands
¹⁴Department of Human Genetics, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, Netherlands
¹⁵Department of Pathology, Hospital Universitario Virgen del Rocío, Sevilla, Spain
¹⁶Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
¹⁷Pediatric Congenital Hematologic Disorders Research Center, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran (Islamic Republic of)
¹⁸Clinical Immunology and Primary Immunodeficiencies Unit, Allergy and Clinical Immunology Department, Hospital Sant Joan de Déu, Barcelona, Spain
¹⁹Study Group for Immune Dysfunction Diseases in Children (GEMDIP), Institut de Recerca Sant Joan de Déu, Barcelona, Spain
²⁰Department of Surgery and Surgical Specializations, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, Barcelona, Spain
²¹Pediatric Infectious Diseases, Rheumatology and Immunology Unit, Hospital Universitario Virgen del Rocío, Institute of Biomedicine of Seville (IBIS)/ Universidad de Sevilla/CSIC, Red de Investigación Traslacional en Infectología Pediátrica RITIP, Sevilla, Spain
²²Medical University of Vienna, Institute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Vienna, Austria
²³Karl Landsteiner University of Health Sciences, Krems, Austria
²⁴Medical University of Vienna, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Vienna, Austria
²⁵Department of Molecular Biomedical Sciences, North Carolina State University, Raleigh, NC
²⁶Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA
²⁷Primary Immunodeficiency Group, Newcastle University Translational and Clinical Research Institute, Newcastle Upon Tyne, United Kingdom
²⁸Klinik für Neuropädiatrie und Stoffwechselerkrankungen, Zentrum für Kinder- und Jugendmedizin, Oldenburg, Germany
²⁹St. Anna Children's Hospital, Vienna, Austria
³⁰Centre for Pediatric and Adolescent Medicine, Department of Pediatric Kidney, Liver and Metabolic Diseases and Neuropediatrics, Hannover Medical School, Hannover, Germany
³¹Allergy and Clinical immunology Department, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran (Islamic Republic of)
³²University of Paris, Paris, France
³³Service d'Hématologie Biologique (Hematology Diagnostic Lab), AP-HP, Hôpital R. Debré, Paris, France
³⁴Laboratory of Excellence for Red Cells, LABEX GR-Ex, Paris, France
³⁵Pediatric Rheumatology Division, Hospital Sant Joan de Déu Barcelona, Esplugues de Llobregat, Barcelona, Spain
³⁶Institute of Cardiovascular and Metabolic Diseases (I2MC), INSERM UMR1297, Paul Sabatier University, Toulouse, France
³⁷Medical University of Vienna, Department of Dermatology, Vienna, Austria

Nicholas F. DeCleene, BS^1,2, Duc T. Nguyen, MD, PhD^2*, Susan E. Kirk, PA-C^1,2*, Hannah L. Helber, MS^1,2*, Ghadir S. Sasa, MD^1,2* and Alison A. Bertuch, MD, PhD^1,2

¹Cancer and Hematology Center, Texas Children's Hospital, Houston, TX
²Department of Pediatrics, Baylor College of Medicine, Houston, TX

Seila De Leon^1*, Michelly Sampaio De Melo, MD^1*, Nisha Patel, DO¹, Alina Dulau Florea, MD^1,2, Irina Maric, MD, MSc³, Raul C. Braylan, MD³, Weixin Wang^1*, Matthew Merguerian^4*, Elizabeth J. Andrews^4,5*, Lea Cunningham, MD^4,6*, David J. Young, MD, PhD⁴, Shawn Chong^4*, Natalie Deuitch, MS^4*, Joie Davis^4*, Kathleen Craft, B.S.N., R.N.^7*, Theo Heller, MD^8*, Pamela Frischmeyer-Guerrerio^9*, Paul Pu Liu, MD, PhD⁴ and Katherine R. Calvo, MD, PhD^3,6

¹Hematology Section, Department of Laboratory Medicine, NIH Clinical Center, Bethesda, MD
²Department of Pathology, Molecular & Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, New York, NY
³Hematology Section, Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD
⁴Oncogenesis and Development Section, National Human Genome Research Institute, NIH, Bethesda, MD
⁵Immune Deficiency Cellular Therapy Program, National Cancer Institute, NIH, Bethesda, MD
⁶Myeloid Malignancies Program, National Institutes of Health, Bethesda, MD
⁷Oncogenesis and Development Section, National Human Genome Research Institute, NIH, Bethesda
⁸4Translational Hepatology Section, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD
⁹Laboratory of Allergic Disease, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD

Alaina M Kelly, MD¹, Lauren G Banaszak, MD², Kelcy Smith-Simmer, MMSc, CGC^3*, Kyle Shoger^1*, Sarah M Donohue, MD^4*, Erin Lowery, MD, MS^1* and Jane E Churpek, MD, MS¹

¹Department of Medicine, The University of Wisconsin-Madison, Madison, WI
²Department of Medicine Division of Hematology, Medical Oncology and Palliative Care, University of Wisconsin–Madison, Madison, WI
³Oncology Genetics, The University of Wisconsin Carbone Cancer Center, Madison, WI
⁴Department of Medicine, Division of Rheumatology, The University of Wisconsin-Madison, Madison, WI