Jonas Bouhlal^1,2,3*, Petra Nygren^2,3,4*, Emmi Jokinen^1,2,3*, Essi Laajala, Ph.D.^1,2,3*, Aleksandr Ianevski^5*, Diogo Dias^1,3,6*, Jay Klievink, M.Sc.^1,2,3*, Hanna Lähteenmäki^1,2,3*, Hanna Duàn, M.Sc.^1,2,3*, Khalid Saeed^1,3*, Dean Anthony Lee, MD, PhD⁷, Tero Aittokallio, PhD^2,8,9,10*, Olli Dufva, M.D., Ph.D.^1,2,3* and Satu Mustjoki, MD, PhD^2,3,11

¹Hematology Research Unit Helsinki, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
²ICAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland
³Translational Immunology Research Program, University of Helsinki, Helsinki, Finland
⁴Hematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Ca, Helsinki, FIN
⁵Institute For Molecular Medicine Finland (FIMM), Helsinki, FIN
⁶Institute For Molecular Medicine Finland (FIMM), Helsinki, Finland
⁷Division of Hematology/Oncology/BMT, Nationwide Children's Hospital, Columbus, OH
⁸Institute for Cancer Research, Department of Cancer Genetics, Oslo University Hospital, Oslo, Norway
⁹Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland
¹⁰Centre for Biostatistics and Epidemiology (OCBE), Faculty of Medicine, University of Oslo, Oslo, Norway
¹¹Hematology Research Unit Helsinki, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland

Mike P. Agius, PhD^1*, Laura Hevenor, BS^1*, N Connor Payne^2,3*, Ralph Mazitschek^3*, Hyuk-Soo Seo^4*, Sirano Dhe-Paganon^4*, Jun Qi^4* and Irene M. Ghobrial, MD^5,6

¹Dana-Farber Cancer Institute, Boston, MA
²Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA
³Center for Systems Biology, Massachusetts General Hospital, Boston, MA
⁴Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA
⁵Broad Institute of MIT and Harvard, Cambridge, MA
⁶Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA

Yuqin Song, MD¹, Shuhua Yi, M.D^2*, Haiyan Yang³, Ru Feng^4*, Huiqiang Huang, MD, PhD^5*, Qingyuan Zhang^6*, Yanyan Liu^7*, Ye Guo^8*, Huilai Zhang^9*, Liling Zhang^10*, Yijiao Qian^11*, JianKun Zhu^11* and Jun Zhu, PhD¹²

¹Department of Lymphoma, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, BEIJING, China
²State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences&Peking Union Medical College, Tianjin, China
³Department of Lymphatic Oncology, Zhejiang Cancer Hospital, Hangzhou, China
⁴Department of Hematology, Nanfang Hospital of Southern Medical University, Guangzhou, China
⁵State Key Laboratory of Oncology in South China, Department of Medical Oncology, Sun Yat-sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China
⁶Department of Lymphoma and Hematology, Harbin Medical University Cancer Hospital, Harbin, China
⁷Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China
⁸Shanghai East Hospital, Shanghai, China
⁹Department of Lymphoma, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin's Clinical Research Center for Cancer, Tianjin, China
¹⁰Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
¹¹Oncology, Eli Lilly and Company, Shanghai, China
¹²Department of Lymphoma, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, Beijing, China

Rachel Cant^1*, Lucy Huitong Li, PhD^2*, May-Li Mackinnon, PhD^2*, Daniel H Wiseman, MBBChir, FRCPath, MRCP, PhD^3*, Kiran Batta, PhD⁴ and Sam Butterworth, PhD^2*

¹Division of Cancer Sciences, University of Manchester, Manchester, ENG, United Kingdom
²Division of Pharmacy and Optometry, University of Manchester, Manchester, United Kingdom
³Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom
⁴Division of Cancer Sciences, The University of Manchester, Manchester, ENG, United Kingdom

Taku Harada^1*, Monika Perez^1*, Jeremie Kalfon^2*, Rashad Batley^1*, Flora Dievenich Braes^1*, Stuart H Orkin, MD^3,4,5 and Maxim Pimkin, MD, PhD⁶

¹Boston Children's Hospital, Boston, MA
²Broad Institute, Cambridge, MA
³Dana-Farber Boston Children’s Cancer and Blood Disorders Center, Boston, MA
⁴Harvard Medical School, Boston, MA
⁵Howard Hughes Medical Institute, Boston
⁶Dana-Farber Cancer Institute, Brookline, MA

Yubin Kang, MD¹, Jian Wu, MD, PhD^1*, Xiaobei Wang, PhD^1*, Parker Mathews^2*, Shaima Jabbar, PhD^1*, George William Schaaf, DVM^3*, John Olson, MA^3*, Joel Ross, PhD^2*, Nelson J. Chao, MD⁴, Mark Cline, DVM, PhD^3* and Peter B. Heifetz, PhD^5*

¹Division of Hematologic Malignancies and Cellular Therapy, Duke University, Durham, NC
²Duke University, Durham, NC
³Wake Forest School of Medicine, Winston-Salem, NC
⁴Division of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University, Durham, NC
⁵OrPro Therapeutics, Inc, San Diego, CA

Ling-Ling Lee^1*, Cong Zhu^2*, Brianna Feldmeier^3*, Yao Chen^4*, Wenyu Li^5*, Yu Chen, MD, PhD⁶, Stephen P. Anthony, DO⁶, Yue Shen, PhD^7*, Fenlai Tan, MD, PhD², Yi Chen, PhD^6* and Bing Dai, PhD^6*

¹Newave Pharmaceutical Inc, Pleasanton, CA
²Guangzhou Lupeng Pharmaceutical Co. Ltd, Guangzhou, China
³Student at Amador Valley High School, internship at Newave Pharmaceutical Inc, Pleasanton, CA
⁴Student at The Quarry Lane School, internship at Newave Pharmaceutical Inc, Pleasanton
⁵Guangdong Provincial People's Hospital, Guangzhou, China
⁶Newave Pharmaceutical Inc., Pleasanton, CA
⁷Guangzhou Lupeng Pharmaceutical Co., Ltd., Guangzhou, China

Fernanda Marconi Roversi, PhD^1,2*, Maura Lima Pereira Bueno, UR^2*, Fernanda Soares Niemann, MSc^2*, Irene Santos, PhD^2*, Nádia Ghinelli Amôr, PhD^2*, Adriana Duarte da Silva Santos, PhD^2*, Audrey Bastos^2* and Sara Teresinha Olalla Saad, MD²

¹Department of Surgery, Emory University, Atlanta, Georgia, USA., Atlanta, GA, Brazil
²Hematology and Transfusion Medicine Center - University of Campinas/Hemocentro-UNICAMP, Campinas, São Paulo, Brazil

James J. Driscoll II, MD, PhD¹, Priyanka S. Rana^2*, Ehsan Malek, MD³ and James J. Ignatz-Hoover, MD, PhD^4*

¹University Hospitals Seidman Cancer Center, Cleveland, OH
²Case Western Reserve University, Cleveland, OH
³Roswell Park Comprehensive Cancer Center, Buffalo, NY
⁴Seidman Cancer Center, University Hospitals Cleveland Medical Center, Cleveland, OH