Ruochen Dong, PhD, BM¹, Hua Li^1*, Xi He, MD^1*, Anoja Perera^1*, Seth Malloy^1*, Jonathon Russell^1*, Wenting Li^1*, Kaitlyn Petentler^1*, Xinjian Mao, PhD¹, Zhe Yang^1*, Michael Epp^1*, Kate Hall^1*, Allison Scott^1*, Sarah Smith^1*, Mark Hembree^1*, Yongfu Wang^1*, Sean McKinney^1*, Jeff Haug^1*, Jay Unruh^1*, Brian Slaughter^1* and Linheng Li, PhD^2,3

¹Stowers Institute for Medical Research, Kansas City, MO
²Stowers Inst. for Med. Rsch., Kansas City, MO
³Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS

Kira A. Young, PhD¹, Maria A. Telpoukhovskaia, PhD^1*, Johanna Hofmann^2*, Konstantinos D. Kokkaliaris, PhD^2*, Jayna J. Mistry, PhD¹ and Jennifer J. Trowbridge, PhD¹

¹The Jackson Laboratory, Bar Harbor, ME
²University Hospital Frankfurt, Frankfurt, Germany

Teodora Diana Supeanu, PhD, DVM^*, Cristian Moldovan^*, Laura Palau, MD^*, Sergiu Pasca, MD^*, Patric Teodorescu, MD^*, Lukasz P. Gondek, MD, PhD and Gabriel Ghiaur, MD, PhD

Sidney Kimmel Comprehensive Cancer Center, Department of Oncology, Johns Hopkins University, Baltimore, MD

Anna Navarro Figueredo, MSc^1*, Wencke Walter, PhD^2*, Jennifer Rivière, PhD^1*, Marit Leilich, MD^1*, Siddhi Pawar, MSc^1*, Michèle Buck, PhD^1*, Judith S. Hecker, MD^1*, Marta Benegas Coll, MSc^3*, Carolina Monzó, PhD^4*, Maki Sakuma, MD^2,5*, Priyansh Srivastava, MSc^3*, Ana Conesa, PhD^3,4*, Torsten Haferlach, MD, PhD², Mark Van Der Garde, PhD^1* and Katharina S. Götze, MD¹

¹Department of Medicine III, Hematology and Oncology, Technical University of Munich School of Medicine, Munich, Germany
²MLL Munich Leukemia Laboratory, Munich, Germany
³BioBam Bioinformatics S.L., Valencia, Spain
⁴Institute for Integrative Systems Biology (CSIC-UV), Spanish National Research Council, Valencia, Spain
⁵Technical University Munich, Medical Graduate Center, Munich, Germany

Martha M. Zarou, PhD^1*, Amy Dawson, PhD^2*, Bodhayan Prasad, PhD^2*, Joana Bittencourt-Silvestre^3*, Désirée Zerbst^2*, Giovanny Rodriguez Blanco, PhD^4*, Mary Scott, PhD^2*, Karen Dunn^3*, Vaidehi Krishnan, PhD^5*, Mhairi Copland, PhD, MBBChir, FRCP, FRCPath³, David Vetrie, PhD^2*, Ravi Bhatia, MD⁶, Seth Coffelt, PhD^4*, S.Tiong Ong, MBBChir^5*, Helen Wheadon, PhD^3*, Sara Zanivan, PhD^4*, Kristina Kirschner, PhD^4* and G. Vignir Helgason, PhD²

¹Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, SCO, United Kingdom
²Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom
³Paul O’Gorman Leukaemia Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom
⁴Cancer Research UK Beatson Institute, Glasgow, United Kingdom
⁵Cancer & Stem Cell Biology Signature Research Programme, Duke-NUS Medical School, Singapore, Singapore
⁶University of Alabama, Birmingham, AL

Xianmin Song, phd¹, Qiaomei He^1*, Xi Sun^1*, Fang Zhang^2*, Pengran Wang^3* and Yan Zhang, PhD^4*

¹Department of Hematology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
²Shanghai Jiaotong University School of Medicine, Shanghai, China
³Department of Hematology, Shanghai, CHN
⁴Department of Hematology, Shanghai General Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, CHN

Itziar Cenzano, PhD^1*, Miguel Cocera^1*, Robert Lehmann, PhD^2*, Jin Ye^2*, Amaia Vilas-Zornoza^1*, Patxi San-Martin^1*, Paula Aguirre-Ruiz^3*, Diego Alignani^1*, Aitziber Lopez^1*, Bruno Paiva^1*, Marta Miñana Barrios, MD^4*, Ignacio Sancho Gonzalez, MD^5*, Javier Ruiz, MD^5*, Sarai Sarvide^1*, Purificacion Ripalda-Cemborain^3*, Laura Sudupe^2*, Emma Muiños-Lopez, PhD^1*, Vincenzo Lagani, PhD^2*, Jesper Tegner, PhD^2*, Borja Saez-Ochoa, PhD^3*, Isabel A Calvo, PhD^3*, David Gomez-Cabrero, PhD^2,6* and Felipe Prosper, MD, PhD^7,8,9

¹Hematology and Oncology Program, Centre for Applied Medical Research (CIMA), Instituto de Investigaciones Sanitarias de Navarra (IdiSNA), Cancer Center Clinica Universidad de Navarra (CCUN), Pamplona, Spain
²Bioscience Program, Biological and Environmental Sciences and Engineering Division (BESE), King Abdullah University of Science and Technology KAUST, Thuwal, Saudi Arabia
³Hematology and Oncology Program, Centre for Applied Medical Research (CIMA), Instituto de Investigaciones Sanitarias de Navarra (IdiSNA), Cancer Center Clinica Universidad de Navarra (CCUN), Pamplona, Spain, Pamplona, Spain
⁴Hospital Reina Sofía de Tudela, Tudela, Spain
⁵Hospital Universitario de Navarra, Pamplona, Spain
⁶Translational Bioinformatics Unit, Navarrabiomed, Universidad Pública de Navarra (UPNA), Pamplona, Spain
⁷Centro de Investigacion Biomedica en Red de Cancer (CIBERONC)., Madrid, Spain
⁸Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), IDISNA, CIBER-ONC number CB16/12/00369 and CB16/12/00489, Pamplona, Spain
⁹Hematology and Cell Therapy Department. Clinica Universidad de Navarra, IdiSNA., Pamplona, Spain

Elory Leonard^*, Lakshmi Sandhow, PhD^*, Huan Cai, PhD^* and Hong Qian, PhD^*

Center for Hematology and Regenerative Medicine (HERM), Department of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden

Stephanie Frenz-Wiessner^1*, Savannah Fairley^1*, Maximilian Buser^2*, Isabel Goek^1*, Kirill Salewskij^3*, Gustav Jonsson^3*, Benedicta zu Putlitz^1*, Daniel Petersheim^1*, David Illig^1*, Yue Li^1*, Pin-Hsuan Chen^1*, Martina Kalauz^1*, Raffaele Conca^1*, Michael Sterr^4*, Johanna Geuder^5*, Yoko Mizoguchi^6*, Daniel Kotlarz^1*, Martina Rudelius^7*, Josef M Penninger^3*, Carsten Marr^2* and Christoph Klein⁸

¹Department of Pediatrics, Dr. von Hauner Children’s Hospital, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany
²Institute of AI for Health, Helmholtz Munich – German Research Center for Environmental Health, Neuherberg, Germany
³Institute of Molecular Biotechnology Austria (IMBA), Vienna, Austria
⁴Institute of Diabetes and Regeneration Research, Helmholtz Diabetes Center, Helmholtz Center Munich, Neuherberg, Germany
⁵Anthropology and Human Genomics, Faculty of Biology, Ludwig-Maximilians-University Munich, Martinsried, Germany
⁶Department of Pediatrics, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan
⁷Institute of Pathology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany
⁸Department of Pediatrics, Dr. von Hauner Children’s Hospital, LMU University Hospital, LMU Munich, Munich, Germany

Laurence C Cheung, PhD, MBA^1,2,3, Sarah Trinder^4*, Anastasia Hughes^1*, Benjamin Mullin^5*, Sarah Rashid^5*, Jinbo Yuan^5*, Jiake Xu, PhD^5*, Owen Duncan^5*, Richard B. Lock, PhD^6,7,8, Sebastien Malinge^1*, Vincent Kuek^1* and Rishi Sury Kotecha, MB ChB, PhD^2,4,9,10*

¹Telethon Kids Institute, Perth, Australia
²Curtin Medical School, Curtin University, Perth, Australia
³Curtin Health Innovation Research Institute, Curtin University, Perth, Australia
⁴Department of Clinical Haematology, Oncology, Blood and Marrow Transplantation, Perth Children's Hospital, Perth, Australia
⁵The University of Western Australia, Perth, Australia
⁶Children’s Cancer Institute, Children's Cancer Inst. Australia Lowy Cancer Research Centre, Univ N.S.W., Randwick, NSW, Australia
⁷University of New South Wales Centre for Childhood Cancer Research, University of New South Wales, Sydney, Australia
⁸School of Women’s and Children’s Health, University of New South Wales, Sydney, Australia
⁹Leukaemia Translational Research Laboratory, Telethon Kids Cancer Centre, Telethon Kids Institute, University of Western Australia, Perth, Australia
¹⁰School of Medicine, University of Western Australia, Perth, Australia

Konur Oyman^1*, Donn Lee Calkins, BS^1*, Wantong Li², Daelynn Buelow, PhD^3*, Sharyn D. Baker, PharmD⁴ and Bradley Wayne Blaser, MD, PhD⁵

¹Division of Hematology, The Ohio State University Wexner Medical Center, Columbus, OH
²Division of Hematology, The Ohio State University, Columbus, OH
³Division of Pharmaceutics & Pharmacology, The Ohio State Univeristy, Lewis Center, OH
⁴Ohio State University, Columbus, OH
⁵Division of Hematology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH