Bhavisha A. Patel, MD¹, Emma M. Groarke, MD², Ruba Shahloub^3*, Jennifer Lotter^4*, Jeanine Superata^5*, Joelle Khoriaty^6*, Kimberly McKernan^6*, Uzoamaka Okeke^6*, Olga Rios^1*, Colin O. Wu, PhD^7* and Neal S. Young, MD¹

¹Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
²Hematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD
³Office of Biostatistics Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda
⁴Hematology Branch, NHLBI, National Institutes of Health, Bethesda, MD
⁵Office of the Clinical Director, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
⁶Office of Clinical Research Support Services, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda
⁷Office of Biostatistics Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD

Alexandra Pike, MBBS, FRCPath, MRCP^1,2*, Natalie Fox, MSc^3*, Claire E McKinley, BSc^3*, Louise M Arnold, BSc (hons)^2*, Mark Harland, PhD^3*, Deborah Clarke, MSc^3*, Briony Forrest, BSc^2*, Nicola Houghton, BSc^2*, Nora Youngs, BSc^2*, Emily Charlton, BSc^2*, Tapiwa Zhakata, BSc^2*, Catherine Barnfield, BSc^2*, Ruth Harvey^4*, Mary Wu^4*, Caitlin Kavanagh^4*, Stephen John Richards, PhD, FRCPath^3*, Daniel Payne, MSc^2*, Abraham Mullasseril Varghese, MBBS, MRCP^5*, Sateesh Nagumantry, MBBS^6*, Talha Munir, MBBS, MRCP, FRCPath, PhD^2*, Petra Muus, MD², Morag Griffin, FRCPath, MRCP^2*, Darren Newton, PhD^7*, Peter Hillmen³ and Richard J Kelly, PhD^2,3*

¹Leeds Institute of Medical Research, University of Leeds, Wakefield, ENG, United Kingdom
²Department of Haematology, St James's University Hospital, Leeds, United Kingdom
³Leeds Institute of Medical Research, University of Leeds, Leeds, United Kingdom
⁴The Francis Crick Institute, London, United Kingdom
⁵Department of Haematology, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
⁶Peterborough City Hospital, Peterborough, United Kingdom
⁷Leeds Institute of Medical Research, University of Leeds, Leeds, ENG, United Kingdom

Caroline I Piatek, MD¹, Flore Sicre De Fontbrune^2*, Fahri Sahin^3*, Wolfgang Füreder^4*, Sandra Fatima Gualandro, MD, PhD^5*, Wilma Barcellini, MD^6*, Masayo Ogawa, MD^7*, Stephan Ortiz, RPh, PhD^7*, Ayca Ozol-Godfrey^7*, Jeff Szer, MBBS, FRACP⁸ and Mustafa Yenerel^9*

¹Jane Anne Nohl Divison of Hematology, Keck School of Medicine, University of Southern California, Los Angeles, CA
²Hematology and Transplant Unit, Saint Louis Hospital, APHP, Paris, France
³Division of Hematology, Department of Internal Medicine,, Ege University, Izmir, Turkey
⁴Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria
⁵Division of Haematology, University of São Paulo Medical School, Sao Paulo, Brazil
⁶Hematology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
⁷Alexion, AstraZeneca Rare Disease, Boston, MA
⁸Department of Clinical Haematology, Peter MacCallum Cancer Centre and the Royal Melbourne Hospital, Melbourne, VIC, Australia, Melbourne, VIC, Australia
⁹Division of Hematology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey, Istanbul, TUR

Austin Kulasekararaj, MD, MBBS, FRCPath, MRCP¹, Hubert Schrezenmeier, MD^2,3, Kensuke Usuki, MD, PhD⁴, Aleksander Kulagin^5*, Sandra Fatima Gualandro, MD, PhD^6*, Rosario Notaro^7,8*, Masayo Ogawa, MD^9*, Ji Yu^10*, Ami Patel, PhD^9*, Yogesh Patel^9*, Wolfgang Füreder^11*, Regis Peffault De Latour^12* and Jong-Wook Lee, MD¹³

¹Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, ENG, United Kingdom
²German Red Cross Blood Transfusion Service Baden-Württemberg-Hessen and University Hospital Ulm, Ulm, Germany
³University of Ulm, Ulm, Germany
⁴NTT Medical Center Tokyo, Tokyo, Japan
⁵5RM Gorbacheva Research Institute, Pavlov University, St Petersburg, RUS
⁶Division of Haematology, University of São Paulo Medical School, Sao Paulo, Brazil
⁷Istituto Per Studio, La Prevenzione E La Rete Oncologica (ISPRO), Florence, ITA
⁸Haematology, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
⁹Alexion, AstraZeneca Rare Disease, Boston, MA
¹⁰Alexion, AstraZeneca Rare Disease, Boston
¹¹Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria
¹²Hôpital Saint-Louis,, Paris, France
¹³Department of Hematology, Seoul St. Mary's Hospital Catholic University of Korea, Seoul, South Korea

Gi June Min¹, Sung-Soo Park^2*, Silvia Park^1*, Jae-Ho Yoon, MD², Seung-Hwan Shin^3*, Sung-Eun Lee, MD^4*, Byoung Sik Cho^1*, Ki-Seong Eom^2*, Yoo-Jin Kim², Seok Lee², Hee-Je Kim^5*, Chang-Ki Min^2*, Seok-Goo Cho^1* and Jong-Wook Lee, MD²

¹Department of Hematology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
²Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
³Department of Hematology, Eunpyeong St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
⁴Leukemia Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
⁵Catholic Hematology Hospital, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Seoul, Korea, Republic of (South)

Richard J. Kelly, BSc, MD^1*, Nicola Houghton, BSc^2*, Talha Munir, MBBS, MRCP, FRCPath, PhD^3*, Petra Muus, MD², Nora Youngs, BSc^2*, Lisa Aurand, MD⁴, Kosalai Mohan^4*, Brian Senk^4*, Rodrigo Pavani^4*, Lorah Perlee, PhD^4*, Amal Souttou^4* and Morag Griffin, FRCPath, MRCP^2*

¹Department of Haematology, St. James’s University Hospital, Leeds, United Kingdom
²Department of Haematology, St James's University Hospital, Leeds, United Kingdom
³Department of Haematology, St. James's University Hospital, Leeds, United Kingdom
⁴Regeneron Pharmaceuticals, Inc., Tarrytown, NY

Shichong Wang, MD^1*, Jiali Huo^2*, Yilin Liu^2*, Lingyun Chen^2*, Xiang Ren^2*, Xingxin Li^2*, Min Wang^2*, Peng Jin^2*, Jinbo Huang^2*, Neng Nie^2*, Jing Zhang^2*, Yingqi Shao^2*, Meili Ge^2*, Yingchang Mi, MD² and Yizhou Zheng^2*

¹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Tian Jin, China
²State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Tianjin, China

Zexing Sun^1,2*, Yilei Hong^1,2*, Wanzhi Jiang^1,2*, Yingying Shen^1*, Huijin Hu^1*, Tonglin Hu^1*, Qi Liu^1,2*, Zhenchao Zhuang^3*, Yuhong Zhou^1*, Baodong Ye, MD^4* and Dijiong Wu, MD, PhD¹

¹Department of Hematology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, China
²The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China
³Department of Clinical Laboratory, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, China
⁴The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China

Sukanya Gogoi, MD^1*, Jennifer Vidler, MBBS, MRCP, FRCPath^2*, Manujasri Wimalachandra, MD, FRCPath, MBBS, MRCP^3*, Wasanthi Wickramasinghe, MBBS, MRCP, FRCPath^3* and Austin Kulasekararaj, MD, MBBS, FRCPath, MRCP^4,5,6

¹Department of Haematological Medicine, King's College Hospital , King's College Hospital NHS Foundation Trust, London, ENG, United Kingdom
²Department of Haematological Medicine, King's College Hospital, King's College Hospital NHS Foundation Trust, London, United Kingdom
³Haematology, King's College Hospital, King's College Hospital NHS Foundation Trust, London, United Kingdom
⁴Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, ENG, United Kingdom
⁵National Institute for Health Research and Wellcome King's Clinical Research Facility, London, United Kingdom
⁶Department of Haematological Medicine, King's College Hospital, London, United Kingdom

Matthew P Connor, MD¹, Neeharika Prathapa, MBBS^1*, Noelle V. Frey, MD, MS¹, Saar Gill, MD, PhD¹, Elizabeth O Hexner, MD, MSTR¹, Ximena Jordan Bruno, MD¹, Catherine Lai, MD¹, Alison W Loren, MD¹, Selina M Luger, MD, FRCPC¹, Andrew H Matthews, MD^1*, Shannon R McCurdy, MD¹, Alexander Perl¹, David L. Porter, MD¹, Arlene Zeringue^2*, Joseph H. Oved, MD^3,4, Timothy S Olson, MD, PhD^4,5, Keith W Pratz, MD¹ and Daria V Babushok, MD, PhD^1,4

¹Division of Hematology/Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA
²Information Services, University of Pennsylvania, Philadelphia, PA
³Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York City, NY
⁴Comprehensive Bone Marrow Failure Center, Children's Hospital of Philadelphia, Philadelphia, PA
⁵Department of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA

Wenrui Yang^1*, Baohang Zhang^1*, Xiangrong Hu^1*, Li Zhang^1*, Liping Jing, MD^2*, Xin Zhao, md¹ and Fengkui Zhang^1*

¹Anemia Therapeutic Center, Institute of Hematology and Blood Diseases Hospital, CAMS & PUMC, Tianjin, China
²Anemia Therapeutic Center, Institute of Hematology and Blood Diseases Hospital, CAMS & PUMC, Tianjin, AL, China

Alexander Röth, MD¹, Christopher J. Patriquin^2*, Jeff Szer, MBBS, FRACP³, Louis Terriou^4*, Ami Patel, PhD^5*, Philippe Gustovic, MD, MSc^5*, Jun-Ichi Nishimura, MD, PhD⁶ and Robert A. Brodsky, MD⁷

¹Department of Hematology and Stem Cell Transplantation, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
²Division of Medical Oncology & Hematology, University Health Network, Toronto, Canada
³Department of Clinical Haematology, Peter MacCallum Cancer Centre and the Royal Melbourne Hospital, Melbourne, VIC, Australia, Melbourne, VIC, Australia
⁴Service de Médecine Interne et Immunologie Clinique, CHU Lille, Lille, France
⁵Alexion, AstraZeneca Rare Disease, Boston, MA
⁶Department of Hematology and Oncology, Osaka University Graduate School of Medicine, Osaka, Japan
⁷Division of Hematology, Johns Hopkins Medicine, Baltimore, MD

Robert Schmouder^1*, Noemi Kaetterer^2*, Kenneth Kulmatycki^3* and Prasanna Kumar Nidamarthy^4*

¹Novartis Pharmaceuticals Corporation, East Hanover, NJ
²Novartis Pharma AG, Basel, Switzerland
³Novartis Institutes of Biomedical Research, Cambridge, MA
⁴Novartis Healthcare Pvt. Ltd., Hyderabad, India

Hiroyuki Takamori, MD^1*, Yasutaka Ueda^2*, Yoshikazu Matsuoka, PhD^3*, Tatsuya Fujioka, MD, PhD^3*, Hideki Makishima, MD, PhD⁴, Yoshiko Murakami, MD, PhD^5*, Taroh Kinoshita, PhD⁵, Satoru Miyano, PhD^6*, Yuzuru Kanakura, MD, PhD², Jun-Ichi Nishimura, MD, PhD², Naoki Hosen, MD, PhD², Seishi Ogawa⁷ and Yasuhito Nannya, MD, PhD⁸

¹Division of Hematopoietic Disease Control, The Institute of Medical Science, The University of Tokyo, Minato-Ku, Japan
²Department of Hematology and Oncology, Osaka University Graduate School of Medicine, Osaka, Japan
³Department of iPS Stem Cell Regenerative Medicine, Kansai Medical University, Osaka, JPN
⁴Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
⁵Laboratory of Immunoglycobiology, Osaka University Rsrch. Inst. for Microbial Diseases, Osaka, JPN
⁶M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan
⁷Department of Pathology and Tumor Biology, Kyoto University Graduate School of Medicine, Sakyoku, KYO, Japan
⁸Division of Hematopoietic Disease Control, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

Meili Ge^*, Jiali Huo^*, Xiang Ren^*, Jinbo Huang^*, Min Wang^*, Neng Nie^*, Jing Zhang^*, Peng Jin^*, Yingchang Mi, MD, Yingqi Shao^* and Yizhou Zheng^*

State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Tianjin, China

Josaura Fernandez Sanchez, MD^1,2, Arushana Maknojia^3*, Enrico Moiso, PhD^4*, Nusrat Shaikh^5*, Hope Hendricks, MD^6*, Hannah Yan, BA, PhD^7*, Ritu Banerjee, MD, PhD^8*, Jeremy Schraw, PhD^2,9*, Megan Baldridge, MD, PhD^10* and Katherine Y. King, MD, PhD¹¹

¹Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, TX
²Texas Children’s Cancer and Hematology Centers, Houston, TX
³Immunology and Microbiology Program, Graduate School of Biomedical Sciences, Baylor College of Medicine, Houston, TX
⁴Koch Institute for Integrative Cancer research at MIT, Cambridge, MA
⁵Pediatrics Research Resources Office, Baylor College of Medicine, Houston, TX
⁶Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN
⁷Immunology Program, Graduate School of Biomedical Sciences, Baylor College of Medicine, Houston, TX
⁸Vanderbilt University Medical Center, Nashville, TN
⁹Center for Epidemiology and Population Health, Department of Pediatrics, Baylor College of Medicine, Houston, TX
¹⁰Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO
¹¹Pediatric Infectious Diseases, Baylor College of Medicine, Houston, TX

Jun Ho Jang, MD, PhD¹, Soo Min Lim^2*, Ciprian Tomuleasa^3,4,5*, Hanna Oliynyk^6*, Theerin Lanamtieng^7*, Jihye Park, DVM, BS^8*, Younsoo Kim^8*, Jinah Jung, MD, PhD^8* and Paola Russo, MD, PhD^8*

¹Division of Hematology-Oncology, Department of Internal Medicine, Samsung Medical Center, Seoul, Korea, Republic of (South)
²Sultanah Aminah Hospital, Johor, Malaysia
³Department of Hematology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
⁴Department of Hematology, Ion Chiricuta Clinical Cancer Center,, Cluj-Napoca, Romania
⁵Medfuture Research Center for Advanced Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
⁶Department of Hematology, Vinnytsia M I Pyrohov Regional Clinical Hospital, Vinnytsia, Ukraine, Vinnytsia, Ukraine
⁷Division of Hematology, Department of Internal Medicine, Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, Khon Kaen, Thailand
⁸Samsung Bioepis, Incheon, Korea, Republic of (South)