Xu Han, PhD, Chih-Chia Su, PhD^*, Zhemin Zhang, PhD^*, Meinan Lyu, PhD^*, Edward Yu, PhD^* and Marvin T. Nieman, PhD

Department of Pharmacology, Case Western Reserve University, Cleveland, OH

Seema Bhatlekar, PhD^1*, Shancy Jacob^2*, Marina Tistao, PhD^1*, Molly Y Mollica, PhD^3*, Nicole Rhoads^4*, Lili Chen, PhD^4*, Bhanu Kanth Manne, PhD^2*, Darian Murray, B.S.^1*, Siqi Guo^1*, Sharon Celeste Morley^5*, Jesse W Rowley, PhD², Matthew T. Rondina, MD^6,7, Raymond Adili, MD⁴, Jose A. Lopez, M.D⁸ and Li Guo, MD, PhD^4,9

¹University of Utah, Salt Lake City, UT
²Molecular Medicine Program, University of Utah, Salt Lake City, UT
³University of Maryland, Baltimore County, Baltimore, MD
⁴Bloodworks Research Institute, Seattle, WA
⁵Washington University School of Medicine, St Louis, MT
⁶Department of Internal Medicine and Geriatric Research and Education Clinical Center, George E. Wahlen VAMC, Salt Lake City, UT
⁷Department of Pathology, University of Utah School of Medicine, University of Utah, Salt Lake City, UT
⁸University of Washington, Bloodworks Research Institute, Seattle, WA
⁹Division of Hematology and Oncology, University of Washington, Seattle, WA

Hyunjun Kim, MS^1*, Kiwon Lee^2*, Gavin Merschel^1* and Mortimer Poncz, MD³

¹Children's Hospital of Philadelphia, Philadelphia, PA
²Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA
³Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA

Yu Hou, PhD^1*, Lingjun Wang^2*, Haoyi Wang^2*, Lu Sun^2*, Ruting Wang^2*, Yubin Li^2* and Ming Hou^2*

¹Qilu Hospital of Shandong University, Jinan, China
²Qilu hospital of Shandong University, Jinan, China

Roberto Aiolfi, PhD¹, Jose A. Fernandez, MD, PhD^2*, Hiroshi Deguchi^1*, Xiao Xu^3*, Jeanine Ahmed^3*, Miriam Hauer-Jensen^3*, John H. Griffin, PhD², Juan Carlos de la Torre^3*, Hartmut Weiler, PhD⁴ and Laurent O. Mosnier, PhD²

¹The Scripps Research Institute, La Jolla, CA
²Scripps Research Institute, La Jolla, CA
³The Scripps Research Institute, La Jolla
⁴Thrombosis and Hemostasis, Versiti Blood Research Institute, Milwaukee, WI

Keiichi Nakata, MD^1,2*, Keigo Akuta, MD, PhD^1,3*, Takaya Endo, MD^1*, Midori Koike, MD^1,2*, Hisashi Kato, MD, PhD¹, Yoshiaki Tomiyama, MD, PhD¹, Naoki Hosen, MD, PhD¹ and Hirokazu Kashiwagi, MD^2*

¹Department of Hematology and Oncology, Osaka University Graduate School of Medicine, Suita, Japan
²Department of Blood Transfusion, Osaka University Hospital, Suita, Japan
³Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Suita, Japan

Nan Jiang^*, Ruxia Zhao^*, Xiang Hu^*, Shuwen Wang^*, Shaoqiu Leng^*, Qi Feng^* and Jun Peng^*

Qilu Hospital of Shandong University, Jinan, China

Chen Jia^1*, Ting Sun^1*, Renchi Yang, MD² and Lei Zhang, MD³

¹Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
²Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China
³State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Tianjin Key Laboratory of Gene Therapy for Blood Diseases, CAMS Key Laboratory of Gene Therapy for Blood Diseases, Tianjin, China

Guadalupe Rojas-Sanchez, PharmB, MSc, PhD¹, Jorge Calzada-Martinez, MSc^2*, Brandon McMahon, MD³, Orlando Esparza, MD^4*, Giovanny Hernandez, BA^4*, Dennis L Le, MBBS^4*, Eric Wartchow, PhD^5*, Tzu Phang, PhD^6*, Travis Nemkov, PhD^6*, Angelo D'Alessandro, PhD⁷, Paola Maycotte, PhD^8*, Andrew Thorburn, PhD^9*, Jose A. Lopez, M.D¹⁰ and Pavel Davizon-Castillo, MD¹¹

¹Bloodworks NW Research Institute, Seattle, WA
²Bloodworks Northwest, Seattle, WA
³University of Colorado School of Medicine, Aurora, CO
⁴Department of Pediatrics Hematology/Oncology and Bone Marrow Transplantation, University of Colorado Anschutz Medical Campus, Aurora, CO
⁵Electron Microscopy Department, Children’s Hospital Colorado, Aurora, CO
⁶University of Colorado Anschutz Medical Campus, Aurora, CO
⁷School of Medicine, University of Colorado Anschutz Campus, Aurora, CO
⁸Centro de Investigación Biomédica de Oriente, OOAD Puebla, IMSS, Puebla, PU, Mexico
⁹Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO
¹⁰University of Washington, Bloodworks Research Institute, Seattle, WA
¹¹1551 Eastlake Ave E #100, Bloodworks Northwest, Seattle, WA

Sruthi Thekke Veedu, phd, Meghna U Naik, MS, John C Kostyak, PhD^* and Ulhas P. Naik, PhD

Cardeza Center for Hemostasis, Thrombosis, and Vascular Biology, Cardeza Foundation for Hematologic Research, Department of Medicine, Thomas Jefferson University, Philadelphia, PA

Suresh Kumar, PhD^1*, Vittorio Pengo, MD^2* and Nicola Pozzi, PhD³

¹Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University, St. Louis, MO
²University of Padova, Padova, PD, ITA
³Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University, Saint Louis, MO

Quan Zhang^1*, Xiaohu Huang, Ph.D.^2*, Szumam Liu, Ph.D.¹, Noritaka Yada, M.D., Ph.D.^1*, Zhe Han, Ph.D.^2,3* and X. Long Zheng, MD, PhD^1,4

¹Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS
²Department of Medicine, University of Maryland School of Medicine, Baltimore, MD
³Center for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD
⁴Institute for Reproductive Medicine and Developmental Sciences, University of Kansas Medical Center, Kansas City, KS

Gowtham K Annarapu, PhD¹, Stefanie Taiclet^2*, Scott Hahn^3*, Deirdre Nolfi-Donegan, MD^4*, Michael Jurczak, Ph.D.^5*, Adam C Straub, PhD^6* and Sruti Shiva, PhD^3*

¹Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA
²University of Pittsburgh, Pittsburgh
³University of Pittsburgh, Pittsburgh, PA
⁴University of Pittsburgh Medical Center, Pittsburgh, PA
⁵Division of Endocrinology, University of Pittsburgh, pittsburgh
⁶Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA

Abigail Ballard^1*, Wolfgang Bergmeier², David Paul^3*, Robert Hugh Lee, PhD^2*, Nigel Mackman, PhD³, Matthew J. Flick, PhD^4*, Ellen O'Shaughnessy, PhD^2*, David Adalsteinsson^2* and Paul Kim^5*

¹University of North Carolina at Chapel Hill, Durham, NC
²University of North Carolina at Chapel Hill, Chapel Hill, NC
³University of North Carolina At Chapel Hill, Chapel Hill, NC
⁴UNC Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC
⁵McMaster University, Hamilton, ON, Canada

Kumar Subramani^1*, Rohan Varshney^1*, Sandeep Subramanian^2*, Jeffrey Bander^3*, Denys Babii^1* and Jasimuddin Ahamed, PhD²

¹Oklahoma Medical Research Foundation, Oklahoma City
²Oklahoma Medical Research Foundation, Oklahoma City, OK
³Mount Sinai Medical School, New York

Sharath Shankar Sarojini, phd, Meghna U Naik, MS, John C Kostyak, PhD^* and Ulhas P. Naik, PhD

Cardeza Center for Hemostasis, Thrombosis, and Vascular Biology, Cardeza Foundation for Hematology Research, Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA

Alexander B Pine, MD, PhD¹, Ayesha Butt, MD², Rolando Garcia-Milian, MLS, AHIP^3*, Sean X Gu, MD, PhD^4*, Valentina Restrepo, MD^5*, Yu Pei Chock, MD, MPH^6*, John Hwa, MD, PhD^7*, Christopher Tormey, MD^8*, Henry M Rinder, MD⁹, George Goshua, MD, MSc¹⁰, H Michael Belmont, MD^11*, Maria Bertolaccini^12*, David Ware Branch, MD^13*, Doruk Erhan, MD, MPH^14*, Nina Kello, MD^15*, Jason Knight^16*, Michelle Petri, MD, MPH^17*, Rohan Willis, MD^18*, Alfred I Lee, MD, PhD¹⁰ and Anish V Sharda, MBBS¹⁹

¹Department of Hematology, Yale University School of Medicine/Connecticut VA, West Haven, CT
²Section of Hematology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT
³Library, Bionformatics Hub, Yale School of Medicine, New Haven, CT
⁴Department of Laboratory Medicine, Yale University School of Medicine, North Haven, CT
⁵Section of Hematology, Yale University School of Medicine, New Haven, CT
⁶Yale School of Medicine, New Haven, CT
⁷Yale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT
⁸Yale University School of Medicine, New Haven, CT
⁹Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT
¹⁰Section of Hematology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT
¹¹Lupus Center, New York University Langone, New York, NY
¹²King's College London, London, GBR
¹³University of Utah, Salt Lake City, UT
¹⁴Barbara Volcker Center for Women and Rheumatic Diseases, Hospital for Special Surgery, New York, NY
¹⁵Rheumatology, Northwell Health, Great Neck, NY
¹⁶University of Michigan, Ann Arbor, MI
¹⁷Johns Hopkins, Johns Hopkins Hospital, MD
¹⁸Antiphospholipid Standardization Laboratory, University of Texas Medical Branch, Galveston, TX
¹⁹Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT

Jiansong Huang, PhD^1*, Xiangjie Lin, PhD^1*, Hanchen Gao^1*, Min Xin^2*, Jing Dai, PhD^2* and Jie Jin, MD¹

¹Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
²Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China