John Roy R Lozada, Atef Ali^*, Abderrahman Day^*, Jacob A Myers^*, Ella Boytim^*, Hannah Bergom^*, Nicholas Zorko, MD, PhD^*, Martin Felices, PhD^*, Jeffrey S Miller, MD, Justin Hwang, PhD^* and Frank Cichocki, PhD

Division of Hematology, Oncology, and Transplantation, University of Minnesota, Minneapolis, MN

Michelle P. Aranha, PhD^1,2,3*, Romanos Sklavenitis-Pistofidis, MD^1,2,3, Yoshinobu Konishi, MD, PhD^1,2,3, Ting Wu, MS^3*, Hong Yue, PhD^4,5*, Elizabeth D. Lightbody, PhD^1,2,3, Mahshid Rahmat, PhD^1,2,3*, Michael Timonian, MD^1,2,3*, Daniel L. Mallory, BS^2,3*, Michael P. Agius, PhD^1,2,3*, Shohreh Varmeh, PhD^2*, Nang Kham Su, MSc^2*, Jacqueline Perry, MPH^2*, Erica M. Horowitz, BA^2*, Maya Davis, BA^2*, Anna Justis, PhD^2*, Radosław P. Nowak, PhD^4,5*, Mark Hamilton, PhD^6*, Daniel Auclair, PhD^6,7*, Catherine R. Marinac, PhD², Eric Fischer, Ph.D.^4,5*, Gad Getz, PhD^3,8* and Irene M. Ghobrial, MD^1,2,3

¹Harvard Medical School, Boston, MA
²Dana-Farber Cancer Institute, Boston, MA
³Broad Institute of MIT and Harvard, Cambridge, MA
⁴Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA
⁵Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA
⁶Multiple Myeloma Research Foundation, Norwalk, CT
⁷Hematology R&D, AstraZeneca, Waltham, MA
⁸Department of Pathology, Massachusetts General Hospital Cancer Center, Boston, MA

Anneka Allman^1*, Brian Gaudette, PhD^1*, Samantha Kelly^1*, Nagham Alouche, PharmD, PhD^2*, Leolene Carrington, PhD^1*, Eric Perkey, MD, PhD^3*, Riley Outen^4*, Ashley Vanderbeck^1*, Katlyn Lederer^1*, Tanner F. Robertson, PhD^5*, Janis K. Burkhardt^5*, Anastasia N. Tikhonova, PhD⁶, Iannis Aifantis, PhD⁷, Ute Koch, PhD^8*, Freddy Radtke, PhD^9*, Burkhard Ludewig, DVM^10*, Lena Tveriakhina, PhD^11*, Achim Gossler, PhD^12*, Christian W. Siebel, PhD^13*, Daniela Gomez Atria, PhD^1*, Sanjiv Luther, PhD^2*, David Allman, PhD^1* and Ivan Maillard¹⁴

¹University of Pennsylvania, Philadelphia, PA
²University of Lausanne, Epalinges, Switzerland
³University of Michigan, Ann Arbor, MI
⁴University of Pennsylvania, Philadelphia
⁵Children's Hospital of Philadelphia, Philadelphia, PA
⁶Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
⁷Department of Pathology, NYU Grossman School of Medicine, New York, NY
⁸EPFL SV ISREC, Lausanne, Switzerland
⁹Ecole Polytechnique Fédlrale De Lausanne (EPFL), Lausanne, Switzerland
¹⁰Cantonal Hospital St.Gallen, St Gallen, Switzerland
¹¹Harvard Medical School, Boston, MA
¹²Hannover Medical School, Hannover, Germany
¹³Genentech, South San Francisco, CA
¹⁴Division of Hematology/Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA

Audrey Le Floch-Ramondou, PhD^*, George Scott^*, Wen-Chi Chen^*, Kirsten Nagashima^*, Andrew Murphy^*, Matthew Sleeman^* and Jamie Orengo^*

Regeneron Pharmaceuticals, Tarrytown, NY

Konstantinos Aliazis, PhD^1*, Anthos Christofides, MD^1,2*, Halil-Ibrahim Aksoylar, PhD^1*, Rushil Shah^1*, Rinku Pal, BS^1*, Nikolaos Patsoukis, PhD^1,3* and Vassiliki A Boussiotis, MD, PhD¹

¹Hematology-Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
²Medicine, Yale University, New Heaven, CT
³Simcere of America, Cambridge, MA

Arghavan Ashouri, PhD^1*, Pathum Kossinna^1*, Xuyao Li^1*, Jahin Kabir^1*, Jianfan Nie^1*, Artem Kushnirenko^1*, Ilham Abbasi^1*, Leandro Venturutti, PhD, BSc^2,3, Zahi Touma, MD, PhD^4,5* and Federico Gaiti, PhD^1,6

¹Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
²Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada
³BC CANCER, Vancouver, BC, Canada
⁴Division of Rheumatology, University of Toronto, Toronto, ON, Canada
⁵Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, ON, Canada
⁶Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada

Daria Vakula, MD, PhD^1*, Ashley Reiland, MS, APRN, FNP-C^2*, Ivan Kingyue Chinn, MD^3*, Sandra Andrea Salinas, PhD^4*, Alexander Patlan Nieto, PhD^3*, Lisa Forbes Satter, MD^5* and Carl E Allen, MD⁶

¹Department of Pediatrics, Texas Children’s Cancer and Hematology Centers, Houston, Baylor College of Medicine, Houston, TX
²Department of Pediatrics, Texas Children’s Hospital Center for Human Immunobiology, Baylor College of Medicine, Houston, TX
³Texas Children’s Hospital Center for Human Immunobiology, Baylor College of Medicine, Houston, TX
⁴Department of Pediatrics, Texas Children’s Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX
⁵Texas Children's Hospital/Baylor College of Medicine, Houston, TX
⁶Baylor College of Medicine, Houston, TX

Mohamed Khalil^1,2, Scott Terhune, PhD^1* and Subramaniam Malarkannan, PhD^1,2,3

¹Microbiology & Immunology, Medical College of Wisconsin, Milwaukee, WI
²Blood Research Institute, Milwaukee, WI
³Department of Medicine, Medical College of Wisconsin, Milwaukee, WI

Peyton E Conrey^1*, Jose Campos^1*, Andrea Mauracher, MD PhD^1*, Samir Sayed^1*, Jolan E. Walter, MD, PhD^2*, Helen Su, MD PhD^3*, Sara Barmettler, MD^4*, Jennifer W Leiding, MD^5*, Megan Cooper, MD PhD^6*, Suzanne P MacFarland, MD^7*, Melanie A Ruffner, MD PhD^1*, Jocelyn R Farmer, MD PhD^8*, V. Koneti Rao, MD⁹ and Sarah E Henrickson, MD PhD^1*

¹Department of Pediatrics, Allergy Immunology Division, Children's Hospital of Philadelphia, Philadelphia, PA
²Division of Allergy & Immunology, Department of Pediatrics, Morsani College of Medicine, University of South Florida at Johns Hopkins All Children’s Hospital, St. Petersburg, FL
³NIAID, NIH, Bethesda, MD
⁴Massachusetts General Hospital, Boston, MA
⁵Johns Hopkins University School of Medicine, Baltimore, MD
⁶Department of Pediatrics, Washington University, St. Louis
⁷Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA
⁸Lahey Health, Boston, MA
⁹NIAID National Institutes of Health, Bethesda, MD

Akira Nishimura^1*, Akihiro Hoshino^1*, Tsubasa Okano^1*, Kunihiko Moriya^2*, Yuichiro Otsuka^3*, Chikako Owada^4,5*, Kaori Kanda^6*, Keisuke Okuno^7*, Takako Miyamura⁸, Takahiro Kamiya^1*, Takeshi Isoda^1*, Hidenori Ohnishi^9*, Tomohiro Morio^1*, Hirokazu Kanegane^10*, Masatoshi Takagi, MD, PhD¹¹ and Kohsuke Imai^2*

¹Tokyo Medical and Dental University, Tokyo, Japan
²National Defense Medical College, Saitama, Japan
³Chiba Kaihin Municipal Hospital, Chiba, Japan
⁴Chiba University Hospital, Chiba, Japan
⁵International University of Health and Welfare, Narita, Japan
⁶Gifu Municipal Hospital, Gifu, Japan
⁷Tottori University, Yonago, Japan
⁸Department of Pediatrics, Osaka University, Osaka, JPN
⁹Gifu University, Gifu, JPN
¹⁰Tokyo Medical and Dental Universtiy (TMDU), Tokyo, JPN
¹¹Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan

Li Jun, MD^1*, Yi Liu^1*, Xia Wei^2*, Zhanshu Liu, MD^3*, Zailiang Yang, MD^4*, Ling Liu^5*, Meiyu Zhou^4*, Guofa Xu, MD^4*, Lanting Chen^3*, Yao Ding^1*, Haike Lei^6*, Zailin Yang^1*, Shuang Chen^1*, Xiaomei Zhang, PhD^1*, Yifeng Tang^1*, Yan Xiong^1*, Jueyin Liu^1*, Dehong Huang^1*, Chunyan Xiao^1*, Jun Liu^1*, Tao Yang^1*, Ying Xiang^1*, Qiying Li^1*, Yingyu Nan^1*, Jieping Li^1*, Yong Zhang, MD, PhD^2*, Yongzhong Wu, MD, PhD^7* and Yao Liu, PhD, MD¹

¹Department of Hematology-Oncology, Chongqing University Cancer Hospital, Chongqing, China
²Department of Hematology, the Third Affiliated Hospital of Chongqing Medical University, Chongqing, China
³Department of Hematology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China
⁴Department of Hematology and Medical Oncology, Chongqing University Fuling Hospital, Chongqing, China
⁵Department of Medical Laboratory, People’s Hospital of Chongqing Liang Jiang New Area, Chongqing, China
⁶Department of Chongqing Cancer Multi-omics Big Data Application Engineering Research Center, Chongqing University Cancer Hospital, Chongqing, China
⁷Department of Radiation Oncology, Chongqing University Cancer Hospital, Chongqing, China

Sizhou Feng^1*, Yuping Fan^2*, Sudong Zhang^3*, Xiaomeng Feng, MD^4*, Yuanfu Xu^5* and Erlie Jiang, PhD¹

¹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Tianjin, China
²State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, CAMS Key Laboratory for Prevention and Control of Hematological Disease Treatment Related Infection, Tianjin, AL, China
³State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, CAMS Key Laboratory for Prevention and Control of Hematological Disease Treatment Related Infection, Tianjin, China
⁴State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical Colleg, tianjin, China
⁵State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, CAMS Key Laboratory for Prevention and Control of Hematological Disease Treatment Related Infection, Tianjin, CHN