65th ASH Annual Meeting & Exposition: 711. Cell Collection and Processing: Poster I

Symposia: Cell Collection and Processing Oral and Poster Abstracts
Poster

Halls G-H (San Diego Convention Center)

Donor T Cell Infusions Limit Novel Immune Checkpoint Therapy in Pancreatic Cancer: Implications for Adoptive T Cell Therapy

Po-Chih Hsu, DMD, PhD^1,2^*, Edmund K. Waller, MD^3,4, Tenzin Passang⁵^*, Shuhua Wang, MD⁶^* and Jian-Ming Li, PhD³^*

¹Department of Oral and Maxillofacial Surgery, Taipei Tzu Chi Hospital, Taipei, Taiwan
²Winship Cancer Institute, Winship Cancer Institute, Emory University, Atalanta, GA
³Winship Cancer Institute, Winship Cancer Institute, Emory University, Atlanta, GA
⁴Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA
⁵Winship Cancer Institute of Emory University, Atlanta, GA
⁶Emory University School of Medicine, Atlanta, GA

2145

Prior Daratumumab Exposure and It's Correlation to Parameters Related to Apheresis Prior to Hematopoietic Stem Cell Transplantation in Multiple Myeloma

Graham D Unis, MD, MSc¹^*, Cesia Gudiel²^*, Ernest Philon, DO³^* and Laura E. Finn, MD⁴

¹Department of Hematology and Oncology, Ochsner Clinical Foundation, New Orleans, LA
²Department of Bone Marrow Transplantion, Ochsner Clinical Foundation, New Orleans, LA
³Ochsner Clinical Foundation, New Orleans, LA
⁴Ochsner Cancer Center, New Orleans, LA

2146

Automatic Generation of Alloreactivity-Reduced Donor Lymphocytes and Hematopoietic Stem Cells from the Same Mobilized Apheresis Product

Eliza Wiercinska, PhD^1,2^*, Patricia Quade-Lyssy^1,2^*, Christiane Hümmer^1,2^*, Josephine Beifuß^1,2^*, Karima Akarach^1,2^*, Carolin Poppe^1,2^*, Valeriya Olevska³^*, Heike Lahnor³^*, Julia Dzionek³^*, Andreas Bosio³^*, Eleni Papanikolaou, PhD^3,4 and Halvard Bonig^1,2,5

¹Faculty of Medicine, Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt, Germany
²Department of Cellular Therapeutics (GMP), German Red Cross Blood Service BaWü-He, Institute Frankfurt, Frankfurt, Germany
³Miltenyi Biotec, Bergisch Gladbach, Germany
⁴Medical School, National and Kapodistrian University of Athens, Athens, Greece
⁵Department of Medicine, Division of Hematology, University of Washington, Seattle, WA

2147

Comparing Phenotyping, Gene Expression, and Function of T Lymphocytes before Mobilization Chemotherapy Versus after Stem Cell Harvesting in Patients with B Cell Lymphoma and Multiple Myeloma

Sheng-Hsuan Chien^1,2^*, Xiuli Wang, PhD³, Wen-Chun Chen, MD⁴^* and Chun-Yu Liu⁵^*

¹Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan, Taipei, Taiwan
²Transfusion medicine, Taipei Veterans General Hospital, Tapei, Taiwan
³City of Hope, Beckman Research Institute, Duarte, CA
⁴Transfusion medicine, Taipei Veterans General Hospital, Taipei, Taiwan
⁵Transfusion Medicine, Taipei Veterans General Hospital, Taipei, Taiwan

2148

Factors Influencing Lymphocyte Collection Efficiency for the Manufacture of CAR-T Cells in Adults with B Cell Malignancies , a Single Center Experience

Safia Belbachir¹^*, Duncan Purtill, MBBS, FRACP, FRCPA¹^*, Paolo Chiappini²^*, Scott Clair¹^* and Allison A Barraclough, BSc, FRACP, FRCPA, MBBS¹

¹Haematology Department Fiona Stanley Hospital Murdoch, wa, Australia
²Pathwest Laboratory Medicine WA, Murdoch, AUS

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^*signifies non-member of ASH

711.P1.15 711. Cell Collection and Processing: Poster I